Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
Search for:
Diabetes mellitus85 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0015 | DB00046 | approved | biotech | Insulin lispro | Indication associated | Details |
| R0021 | DB00071 | approved | biotech | Insulin pork | Indication associated | Details |
| R0065 | DB00178 | approved | small molecule | Ramipril | Therapeutic strategy associated | Details |
| R0088 | DB00227 | approved; investigational | small molecule | Lovastatin | Therapeutic strategy associated | Details |
| R0144 | DB00414 | approved; investigational; withdrawn | small molecule | Acetohexamide | Indication associated | Details |
| R0168 | DB00489 | approved | small molecule | Sotalol | Indication associated | Details |
| R0169 | DB00491 | approved | small molecule | Miglitol | Indication associated | Details |
| R0170 | DB00492 | approved | small molecule | Fosinopril | Indication associated | Details |
| R0175 | DB00519 | approved | small molecule | Trandolapril | Indication associated | Details |
| R0227 | DB00641 | approved | small molecule | Simvastatin | Therapeutic strategy associated | Details |
| R0257 | DB00731 | approved; investigational | small molecule | Nateglinide | Target associated | Details |
| R0259 | DB00738 | approved; investigational | small molecule | Pentamidine | Indication associated | Details |
| R0300 | DB00834 | approved; investigational | small molecule | Mifepristone | Indication associated | Details |
| R0303 | DB00839 | approved; investigational | small molecule | Tolazamide | Indication associated | Details |
| R0330 | DB00912 | approved; investigational | small molecule | Repaglinide | Target associated | Details |
| R0331 | DB00914 | approved; investigational; withdrawn | small molecule | Phenformin | Indication associated | Details |
| R0371 | DB01016 | approved | small molecule | Glyburide | Indication associated | Details |
| R0391 | DB01067 | approved; investigational | small molecule | Glipizide | Therapeutic strategy associated | Details |
| R0415 | DB01124 | approved; investigational | small molecule | Tolbutamide | Indication associated | Details |
| R0429 | DB01156 | approved | small molecule | Bupropion | Indication associated | Details |
| R0467 | DB01251 | approved; investigational | small molecule | Gliquidone | Indication associated | Details |
| R0476 | DB01278 | approved; investigational | small molecule | Pramlintide | Therapeutic strategy associated | Details |
| R0480 | DB01289 | investigational | small molecule | Glisoxepide | Indication associated | Details |
| R0485 | DB01306 | approved | biotech | Insulin aspart | Indication associated | Details |
| R0486 | DB01307 | approved | biotech | Insulin detemir | Indication associated | Details |
| R0487 | DB01309 | approved | biotech | Insulin glulisine | Indication associated | Details |
| R0507 | DB01382 | approved; investigational | small molecule | Glymidine | Indication associated | Details |
| R0637 | DB04878 | investigational | small molecule | Voglibose | Indication associated | Details |
| R0655 | DB04936 | investigational | small molecule | Tagatose | Indication associated | Details |
| R0663 | DB04963 | investigational | biotech | rhGAD65 | Indication associated | Details |
| R0664 | DB04971 | investigational | small molecule | Reglitazar | Target associated | Details |
| R0673 | DB05001 | investigational | small molecule | PSN9301 | Therapeutic strategy associated | Details |
| R0678 | DB05025 | investigational | small molecule | Arimoclomol | Indication associated | Details |
| R0682 | DB05044 | investigational | small molecule | PSN357 | Indication associated | Details |
| R0687 | DB05053 | investigational | small molecule | MB-07803 | Indication associated | Details |
| R0690 | DB05064 | investigational | small molecule | INCB13739 | Therapeutic strategy associated | Details |
| R0704 | DB05115 | investigational | small molecule | NN344 | Indication associated | Details |
| R0706 | DB05119 | investigational | small molecule | Rilapladib | Indication associated | Details |
| R0707 | DB05120 | investigational | small molecule | AT1391 | Indication associated | Details |
| R0718 | DB05145 | investigational | biotech | TH0318 | Indication associated | Details |
| R0722 | DB05166 | investigational | small molecule | APD668 | Indication associated | Details |
| R0783 | DB05399 | investigational | small molecule | Succinobucol | Therapeutic strategy associated | Details |
| R0798 | DB05433 | investigational | small molecule | rGLP-1 | Therapeutic strategy associated | Details |
| R0807 | DB05464 | investigational | small molecule | NOX-700 | Indication associated | Details |
| R0816 | DB05490 | investigational | small molecule | AMG-131 | Target associated | Details |
| R0818 | DB05496 | investigational | biotech | Otelixizumab | Indication associated | Details |
| R0821 | DB05506 | investigational | small molecule | ISIS 113715 | Therapeutic strategy associated | Details |
| R0826 | DB05518 | investigational | small molecule | Managlinat dialanetil | Indication associated | Details |
| R0838 | DB05631 | investigational | small molecule | ALT-2074 | Indication associated | Details |
| R0840 | DB05645 | investigational | small molecule | Larazotide | Indication associated | Details |
| R0844 | DB05667 | approved; investigational | small molecule | Levoketoconazole | Indication associated | Details |
| R0870 | DB05775 | investigational | small molecule | CRx-401 | Indication associated | Details |
| R0878 | DB05819 | investigational | biotech | NBI-6024 | Indication associated | Details |
| R0886 | DB05854 | investigational | small molecule | CLX-0921 | Target associated | Details |
| R0914 | DB06011 | investigational | small molecule | AMG-222 | Indication associated | Details |
| R0927 | DB06111 | experimental | small molecule | AB192 | Indication associated | Details |
| R0928 | DB06127 | investigational | small molecule | Bisegliptin | Indication associated | Details |
| R0938 | DB06190 | investigational | small molecule | Solabegron | Indication associated | Details |
| R0942 | DB06203 | approved | small molecule | Alogliptin | Indication associated | Details |
| R0959 | DB06253 | investigational | small molecule | Thioctic acid tromethamine | Indication associated | Details |
| R0984 | DB06333 | investigational | small molecule | Trodusquemine | Therapeutic strategy associated | Details |
| R0985 | DB06335 | approved | small molecule | Saxagliptin | Indication associated | Details |
| R1034 | DB06510 | investigational | small molecule | Muraglitazar | Target associated | Details |
| R1037 | DB06519 | investigational | small molecule | Edaglitazone | Indication associated | Details |
| R1038 | DB06521 | investigational | small molecule | Ertiprotafib | Target associated | Details |
| R1041 | DB06533 | investigational | small molecule | Ragaglitazar | Target associated | Details |
| R1042 | DB06536 | investigational | small molecule | Tesaglitazar | Target associated | Details |
| R1058 | DB06606 | investigational | biotech | Teplizumab | Indication associated | Details |
| R1070 | DB06651 | investigational | small molecule | DiaPep 277 | Indication associated | Details |
| R1107 | DB06824 | approved; investigational | small molecule | Triethylenetetramine | Therapeutic strategy associated | Details |
| R1161 | DB08822 | approved; investigational | small molecule | Azilsartan medoxomil | Target associated | Details |
| R1168 | DB08842 | approved; investigational | small molecule | Acetylcarnitine | Therapeutic strategy associated | Details |
| R1200 | DB09043 | approved | biotech | Albiglutide | Target associated | Details |
| R1275 | DB09265 | approved | small molecule | Lixisenatide | Target associated | Details |
| R1318 | DB09564 | approved | biotech | Insulin degludec | Indication associated | Details |
| R1322 | DB10770 | approved | biotech | Foreskin fibroblast (neonatal) | Target associated | Details |
| R1383 | DB11605 | approved | small molecule | Myrrh | Therapeutic strategy associated | Details |
| R1410 | DB11827 | approved; investigational | small molecule | Ertugliflozin | Target associated | Details |
| R1413 | DB11842 | approved; investigational | small molecule | Angiotensin II | Target associated | Details |
| R1427 | DB12007 | experimental | small molecule | Isoflavone | Therapeutic strategy associated | Details |
| R1459 | DB12662 | investigational | small molecule | Naveglitazar | Target associated | Details |
| R1485 | DB13174 | experimental | small molecule | Rhein | Therapeutic strategy associated | Details |
| R1557 | DB15226 | approved; investigational | biotech | Dasiglucagon | Indication associated | Details |
| R1568 | DB15661 | investigational | small molecule | Molnupiravir | Indication associated | Details |
| R1590 | DB16165 | approved; investigational | small molecule | Finerenone | Therapeutic strategy associated | Details |