Bioactive Compound Details
| Compound ID: | B124821 |
| Source ID: | CHEMBL3286797 |
| Source Type: | Small molecule |
| Compound Name: | PF-04418948 |
| Synonyms: | PF-04418948 |
| Molecular Formula: | C23H20FNO5 |
| SMILES: | COc1ccc2cc(OCC3(C(=O)O)CN(C(=O)c4ccc(F)cc4)C3)ccc2c1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T11 | Caspase-3 | CASP3 | inhibitor | Enzyme | P42574 | CASP3_HUMAN | Details |
| T14 | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 | inhibitor | Enzyme | Q99683 | M3K5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T42 | Serine/threonine-protein kinase 17B | STK17B | inhibitor | Kinase | O94768 | ST17B_HUMAN | Details |
| T08 | Tumor necrosis factor | TNF | inhibitor | Cytokine | P01375 | TNFA_HUMAN | Details |
| T23 | Type-1 angiotensin II receptor | AGTR1 | antagonist | GPCR | P30556 | AGTR1_HUMAN | Details |