Bioactive Compound Details
| Compound ID: | B139560 |
| Source ID: | CHEMBL4551344 |
| Source Type: | None |
| Compound Name: | A-1210227 |
| Synonyms: | -- |
| Molecular Formula: | C44H41ClF3N7O7S |
| SMILES: | O=C(NS(=O)(=O)c1ccc(NCC2CCOCC2)c([N+](=O)[O-])c1)c1ccc(N2CCN(Cc3ccc(C(F)(F)F)cc3-c3ccc(Cl)cc3)CC2)cc1Oc1cnc2[nH]ccc2c1 |
| Molecular Species: | ACID |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T14 | Mitogen-activated protein kinase kinase kinase 5 | MAP3K5 | inhibitor | Enzyme | Q99683 | M3K5_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T42 | Serine/threonine-protein kinase 17B | STK17B | inhibitor | Kinase | O94768 | ST17B_HUMAN | Details |
| T08 | Tumor necrosis factor | TNF | inhibitor | Cytokine | P01375 | TNFA_HUMAN | Details |
| T23 | Type-1 angiotensin II receptor | AGTR1 | antagonist | GPCR | P30556 | AGTR1_HUMAN | Details |