Bioactive Compound Details
| Compound ID: | B143787 |
| Source ID: | CHEMBL572 |
| Source Type: | Small molecule |
| Compound Name: | NITROFURANTOIN |
| Synonyms: | BERKFURIN|CEDURAN|Dantafur|FURALAN|Furadantin|GENFURA|Ivadantin|MACROBID|Macrodantin|NITROFURANTOIN|NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS)|NITROFURANTOIN ANHYDROUS|NITROFURANTOIN MACROCRYSTAL|NITROFURANTOIN MACROCRYSTALLINE|NITROFURANTOIN, MACROCRYSTALLINE|NITROFURANTOIN, MACROCRYSTALS|NITROFURANTOINUM ANHYDROUS|NSC-2107|NSC-44150|Nitrofurantoin |
| Molecular Formula: | C8H6N4O5 |
| SMILES: | O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1 |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T12 | Caspase-7 | CASP7 | inhibitor | Enzyme | P55210 | CASP7_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |