Investigational Drugs
Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.
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581 records.
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D480 | Guanabenz | Chemical drug | DB00629 | -- | -- | Under clinical trials | Details |
| D481 | HEC88473 | Chemical drug | -- | GLP-1 agonist; FGF21 agonist | -- | Under clinical trials | Details |
| D482 | Heme Oxygenase | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D484 | Idebenone | Chemical drug | DB09081 | -- | -- | Under clinical trials | Details |
| D485 | IMM 124-E | Supplement | -- | -- | -- | Under clinical trials | Details |
| D488 | LB-P6 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D489 | Leronlimab | Biological drug | DB05941 | -- | -- | Under clinical trials | Details |
| D491 | Methyl-D9-choline | Chemical drug | DB12628 | -- | -- | Under clinical trials | Details |
| D492 | EDP-297 | Chemical drug | -- | FXR agonist | Anti-fibrotic effects | Under clinical trials | Details |
| D493 | MET642 | Chemical drug | -- | FXR agonist | -- | Under clinical trials | Details |
| D494 | Mitoquinone mesylate | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D495 | MK-3655 | Chemical drug | -- | β-Klotho/FGFR1c agonist | -- | Under clinical trials | Details |
| D496 | Montelukast | Chemical drug | DB00471 | -- | -- | Under clinical trials | Details |
| D497 | Namodenoson | Chemical drug | -- | A3 adenosine receptor agonist | Anti-inflammatory | Under clinical trials | Details |
| D498 | NNC0194-0499 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D499 | NS-0200 | Combinatory | -- | -- | -- | Under clinical trials | Details |
| D500 | Ornithine Aspartic Acid Granules | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D502 | PF-07202954 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D503 | Silybin-phospholipids complex | Combinatory | -- | -- | -- | Under clinical trials | Details |
| D504 | Polyunsaturated Fatty Acids | Supplement | -- | -- | -- | Under clinical trials | Details |
| D505 | RXC007 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D506 | SNP-630 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D507 | Tilmanocept | Chemical drug | DB15373 | -- | -- | Under clinical trials | Details |
| D508 | Technetium Tc 99M Mebrofenin | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D510 | Trigonella Foenum-graecum Seed Extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D512 | VK2735 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D513 | VK2809 | Chemical drug | DB15137 | THR-β agonist | -- | Under clinical trials | Details |
| D514 | XW003 | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D515 | XZP-5610 | Chemical drug | -- | FXR agonist | -- | Under clinical trials | Details |
| D516 | XZP-6019 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D517 | LB-P8 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D518 | ALT-801 | Biological drug | DB15386 | -- | -- | Under clinical trials | Details |
| D519 | AstraZeneca | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D520 | BMS-963272 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D521 | BMS-986171 | Chemical drug | -- | Fibroblast growth factor replacements | Antifibrotics; Fibroblast growth factors; Hepatoprotectants | Under clinical trials | Details |
| D522 | Caffeic acid | Chemical drug | -- | STAT3 transcription factor inhibitor | -- | Under clinical trials | Details |
| D523 | Capparis Spinosa Fruit pickle | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D524 | Carom copticum | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D525 | Dava AL-balgham | Traditional medicine | -- | -- | anti-inflammatory; Anti Atherogenic; antioxidants | Under clinical trials | Details |
| D526 | DUR-928 | Chemical drug | -- | DNA methylation inhibitors; Inflammation mediator modulators; Lipid modulators | Anti-inflammatories; Antipsoriatics; Hepatoprotectants | Under clinical trials | Details |
| D527 | EPA/DHA | Supplement | DB11133 | -- | -- | Under clinical trials | Details |
| D529 | Gan-Jiang Ling-Zhu decoction | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D530 | GDD3898 | Chemical drug | -- | -- | Hepatoprotectants; Obesity therapies | Under clinical trials | Details |
| D531 | GLP-1 analogue | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D532 | Kashoos herbal syrup | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D533 | Lisinopril | Chemical drug | DB00722 | ACE inhibitor | -- | Under clinical trials | Details |
| D534 | Lepicol probiotic | Supplement | -- | -- | -- | Under clinical trials | Details |
| D535 | LM011 | Chemical drug | -- | -- | Hepatoprotectants | Under clinical trials | Details |
| D536 | Lycium barbarum polysaccharide supplementation | Supplement | -- | -- | -- | Under clinical trials | Details |
| D537 | Lycopene supplementation | Supplement | -- | -- | -- | Under clinical trials | Details |