| Trial ID: | L0635 |
| Source ID: | IRCT201301223140N6
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| Associated Drug: |
Probiotic
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| Title: |
The effects of probiotic, prebiotic and concomitant supplementation of probiotic, Prebiotic on the oxidative stress, inflammatory and insulin resistance indices, lipid profile and liver function in non-alcoholic fatty liver. patients.
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| Acronym: |
--
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| Status: |
Not Recruiting
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| Study Results: |
No Results Available
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| Results: |
--
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| Conditions: |
Non alcoholic fatty liver. <br>Other diseases of liver;Other diseases of liver
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| Interventions: |
Intervention 1: Intervention groups: Group1 treated with 1 gr of probiotic capcul (107 Bifidobacterium longum and Lactobacillus acidophilus) and 5 gr of prebiotic plasebo (multodextrose) twice a day for 3 months. Group 2 treated with 5 gr of prebiotic (in
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| Outcome Measures: |
AST. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;ALT. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;?GT. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;ALP. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;ALB. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;BIL. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;TC. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;TG. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;LDL. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;HDL. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;Hs-CRP. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;TNF-a. Timepoint: Befor and after intervention. Method of measurement: Serum of blood,ELISA.;IL-6. Timepoint: Befor and after intervention. Method of measurement: Serum of blood,ELISA.;MDA. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;TAC. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;Insulin. Timepoint: Befor and after intervention. Method of measurement: Serum of blood,ELISA.;FBS. Timepoint: Befor and after intervention. Method of measurement: serum of blood, by outoanalyzer.;HOMA-IR. Timepoint: Befor and after intervention. Method of measurement: srrum insulin*FBS/405.Body mass index. Timepoint: Befor and after intervention. Method of measurement: W/H2.;WRT. Timepoint: Befor and after intervention. Method of measurement: waist to hip ratio.;Intake micro and macro nutrients. Timepoint: Befor and after intervention. Method of measurement: Three days weighing food questionnaires.
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| Sponsor/Collaborators: |
Vice-chancellor for research-Tabriz University of Medical Science
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| Gender: |
All
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| Age: |
20 years60 years
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| Phases: |
Phase 2
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| Enrollment: |
88
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| Study Type: |
interventional
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| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment.
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| Start Date: |
16/01/2014
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| Completion Date: |
--
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| Results First Posted: |
--
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| Last Update Posted: |
22 February 2018
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| Locations: |
Iran (Islamic Republic of)
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| URL: |
http://en.irct.ir/trial/3178
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