Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
Article ID | PMID | Source | Title | Publish Year | |
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A05861 | 33097932 | J Nutr | Soy Food Intake Is Inversely Associated with Newly Diagnosed Nonalcoholic Fatty Liver Disease in the TCLSIH Cohort Study. | 2020 | Details |
A05863 | 33096235 | J Nutr Biochem | Nobiletin alleviates high-fat diet-induced nonalcoholic fatty liver disease by modulating AdipoR1 and gp91phox expression in rats. | 2020 | Details |
A05864 | 33096115 | Life Sci | The mother relationship between insulin resistance and non-alcoholic steatohepatitis: Glucosinolates hydrolysis products as a promising insulin resistance-modulator and fatty liver-preventer. | 2020 | Details |
A05866 | 33096076 | Metabolism | Pharmacological activation of REV-ERBα improves nonalcoholic steatohepatitis by regulating intestinal permeability. | 2020 | Details |
A05873 | 33093014 | Diabetes | ETV5 Regulates Hepatic Fatty Acid Metabolism Through PPAR Signaling Pathway. | 2020 | Details |
A05909 | 33078906 | FASEB J | Angiotensin-(1-7), the product of ACE2 ameliorates NAFLD by acting through its receptor Mas to regulate hepatic mitochondrial function and glycolipid metabolism. | 2020 | Details |
A05923 | 33075504 | Diabetes Metab | Lean non-alcoholic fatty liver disease and risk of incident diabetes in a euglycaemic population undergoing health check-ups: A cohort study. | 2020 | Details |
A05927 | 33073044 | Transl Gastroenterol Hepatol | Pathogenesis and pathways: nonalcoholic fatty liver disease & alcoholic liver disease. | 2020 | Details |
A05933 | 33071981 | Front Endocrinol (Lausanne) | Carotid Extra-Media Thickness in Children: Relationships With Cardiometabolic Risk Factors and Endothelial Function. | 2020 | Details |
A05946 | 33067533 | Sci Rep | HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. | 2020 | Details |
A05947 | 33066497 | J Pers Med | Genetic Ablation of MiR-22 Fosters Diet-Induced Obesity and NAFLD Development. | 2020 | Details |
A05952 | 33064664 | Endocr Connect | The hepatic lipidome and HNF4α and SHBG expression in human liver. | 2020 | Details |
A05953 | 33064150 | J Clin Endocrinol Metab | The PNPLA3-I148M Variant Confers an Antiatherogenic Lipid Profile in Insulin-resistant Patients. | 2021 | Details |
A05954 | 33063664 | Elife | Weight loss, insulin resistance, and study design confound results in a meta-analysis of animal models of fatty liver. | 2020 | Details |
A05958 | 33061754 | Turk Pediatri Ars | The association of lipid metabolism and non-alcoholic fatty liver disease in children with obesity. | 2020 | Details |
A05959 | 33061687 | Hepat Med | Efficacy of Glucagon-Like Peptide-1 Analogs in Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2020 | Details |
A05964 | 33060043 | Dig Liver Dis | Antioxidant activity of Hydroxytyrosol and Vitamin E reduces systemic inflammation in children with paediatric NAFLD. | 2020 | Details |
A05972 | 33057854 | Curr Diab Rep | Tissue-Specific Fructose Metabolism in Obesity and Diabetes. | 2020 | Details |
A05976 | 33053981 | Zhonghua Gan Zang Bing Za Zhi | [Physical activity intervention for non-alcoholic fatty liver disease in children]. | 2020 | Details |
A05986 | 33050482 | Int J Mol Sci | Early Pro-Inflammatory Remodeling of HDL Proteome in a Model of Diet-Induced Obesity: 2H2O-Metabolic Labeling-Based Kinetic Approach. | 2020 | Details |
A05997 | 33045675 | J Trace Elem Med Biol | A pilot study of the effects of chromium picolinate supplementation on serum fetuin-A, metabolic and inflammatory factors in patients with nonalcoholic fatty liver disease: A double-blind, placebo-controlled trial. | 2020 | Details |
A06003 | 33040692 | Trop Doct | Effects of anthropometric and metabolic parameters on transaminase levels and liver stiffness in patients with non-alcohol fatty liver disease. | 2020 | Details |
A06020 | 33037249 | Sci Rep | Pathophysiology of high fat diet induced obesity: impact of probiotic banana juice on obesity associated complications and hepatosteatosis. | 2020 | Details |
A06034 | 33033564 | World J Hepatol | Clinical implications, diagnosis, and management of diabetes in patients with chronic liver diseases. | 2020 | Details |
A06038 | 33032263 | J Endocrinol | Lactobacillus pentosus strain S-PT84 improves steatohepatitis by maintaining gut permeability. | 2020 | Details |
A06040 | 33031969 | Ann Hepatol | Non-invasive diagnosis of non-alcoholic fatty liver disease using an algorithm combining clinical indexes and ultrasonographic measures. | 2020 | Details |
A06049 | 33028338 | Lipids Health Dis | The triglyceride-glucose index is associated with the severity of hepatic steatosis and the presence of liver fibrosis in non-alcoholic fatty liver disease: a cross-sectional study in Chinese adults. | 2020 | Details |
A06058 | 33025629 | NMR Biomed | In vivo absolute quantification of hepatic γ-ATP concentration in mice using 31 P MRS at 11.7 T. | 2020 | Details |
A06074 | 33015726 | Curr Diab Rep | Role of Agents for the Treatment of Diabetes in the Management of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A06081 | 33013688 | Front Endocrinol (Lausanne) | Abdominal Adiposity and Total Body Fat as Predictors of Cardiometabolic Health in Children and Adolescents With Obesity. | 2020 | Details |
A06089 | 33010471 | Mol Metab | Dysregulated lipid metabolism links NAFLD to cardiovascular disease. | 2020 | Details |
A06097 | 33008924 | J Lipid Res | Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition. | 2020 | Details |
A06099 | 33007695 | Food Chem | Polyphenols of cambuci (Campomanesia phaea (O. Berg.)) fruit ameliorate insulin resistance and hepatic steatosis in obese mice. | 2020 | Details |
A06109 | 33004402 | BMJ Open Diabetes Res Care | Metabolic and energetic benefits of microRNA-22 inhibition. | 2020 | Details |
A06112 | 33002297 | Mol Nutr Food Res | Huangjinya Black Tea Alleviates Obesity and Insulin Resistance via Modulating Fecal Metabolome in High-Fat Diet-Fed Mice. | 2020 | Details |
A06113 | 33002003 | PLoS One | REV-ERB agonism improves liver pathology in a mouse model of NASH. | 2020 | Details |
A06122 | 32998095 | Diabetes Metab Syndr | Pathophysiological mechanisms underlying MAFLD. | 2020 | Details |
A06130 | 32994765 | Postepy Dermatol Alergol | Non-alcoholic fatty liver disease in patients with psoriasis: therapeutic implications. | 2019 | Details |
A06139 | 32992082 | Phytomedicine | Integrated omics analysis unraveled the microbiome-mediated effects of Yijin-Tang on hepatosteatosis and insulin resistance in obese mouse. | 2020 | Details |
A06140 | 32991990 | J Steroid Biochem Mol Biol | Involvement of endogenous testosterone in hepatic steatosis in women with polycystic ovarian syndrome. | 2020 | Details |
A06144 | 32990607 | Asia Pac J Clin Nutr | Impact of a low-carbohydrate and high-fiber diet on nonalcoholic fatty liver disease. | 2020 | Details |
A06155 | 32984791 | JHEP Rep | Association between remnant lipoprotein cholesterol levels and non-alcoholic fatty liver disease in adolescents. | 2020 | Details |
A06156 | 32984364 | Front Med (Lausanne) | Disturbances in Cholesterol Homeostasis and Non-alcoholic Fatty Liver Diseases. | 2020 | Details |
A06165 | 32981283 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | [Effects of liraglutide combined with vitamin D on non-alcoholic fatty liver induced by high fat in mice and its mechanism]. | 2020 | Details |
A06172 | 32979184 | Obes Surg | Prevalence and Factors Associated with Hepatic Iron Overload in Obese Individuals Undergoing Bariatric Surgery: a Cross-Sectional Study. | 2020 | Details |
A06178 | 32978491 | Sci Rep | FIB-4 index is a marker for a subsequent decrease in insulin secretion in a non-diabetic Japanese population. | 2020 | Details |
A06182 | 32977558 | Molecules | Distinct Influence of Hypercaloric Diets Predominant with Fat or Fat and Sucrose on Adipose Tissue and Liver Inflammation in Mice. | 2020 | Details |
A06184 | 32977263 | J Affect Disord | Association between depression and nonalcoholic fatty liver disease: Contributions of insulin resistance and inflammation. | 2020 | Details |
A06195 | 32973925 | Therap Adv Gastroenterol | The role of the gut microbiome and exercise in non-alcoholic fatty liver disease. | 2020 | Details |
A06196 | 32973715 | Front Microbiol | Constant Light Exposure Alters Gut Microbiota and Promotes the Progression of Steatohepatitis in High Fat Diet Rats. | 2020 | Details |
A06210 | 32966467 | Food Funct | Vitamin D and non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2020 | Details |
A06218 | 32964054 | J Diabetes Res | Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. | 2020 | Details |
A06219 | 32963741 | Iran J Basic Med Sci | The role of acylated ghrelin and unacylated ghrelin in the blood and hypothalamus and their interaction with nonalcoholic fatty liver disease. | 2020 | Details |
A06220 | 32963510 | PPAR Res | Diet Modifies Pioglitazone's Influence on Hepatic PPARγ-Regulated Mitochondrial Gene Expression. | 2020 | Details |
A06227 | 32961669 | Nutrients | Effects of Dietary and Lifestyle Interventions on Liver, Clinical and Metabolic Parameters in Children and Adolescents with Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2020 | Details |
A06228 | 32961610 | J Diabetes Investig | Prevalence of non-alcoholic fatty liver disease and factors associated with it in Indian women with a history of gestational diabetes mellitus. | 2020 | Details |
A06232 | 32961235 | Life Sci | Liraglutide modulates gut microbiome and attenuates nonalcoholic fatty liver in db/db mice. | 2020 | Details |
A06235 | 32959866 | Food Funct | Two polyphenol-rich Brazilian fruit extracts protect from diet-induced obesity and hepatic steatosis in mice. | 2020 | Details |
A06238 | 32958032 | Orphanet J Rare Dis | Consensus clinical management guidelines for Alström syndrome. | 2020 | Details |
A06243 | 32953932 | Mol Ther Methods Clin Dev | Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes. | 2020 | Details |
A06251 | 32952340 | World J Gastroenterol | Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice. | 2020 | Details |
A06255 | 32951743 | Complement Ther Med | Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial. | 2020 | Details |
A06256 | 32951715 | Complement Ther Med | The effect of melatonin on treatment of patients with non-alcoholic fatty liver disease: a randomized double blind clinical trial. | 2020 | Details |
A06258 | 32951410 | Clin Mol Hepatol | Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases. | 2020 | Details |
A06274 | 32945071 | Diabetes Obes Metab | A look to the future in non-alcoholic fatty liver disease: Are glucagon-like peptide-1 analogues or sodium-glucose co-transporter-2 inhibitors the answer? | 2020 | Details |
A06279 | 32943747 | Sci Rep | Difference in lifestyle and metabolic profile of non-alcoholic fatty liver disease with raised alanine amino-transferases between obese and non-overweight subjects. | 2020 | Details |
A06281 | 32943651 | Sci Rep | Punica granatum L.-derived omega-5 nanoemulsion improves hepatic steatosis in mice fed a high fat diet by increasing fatty acid utilization in hepatocytes. | 2020 | Details |
A06284 | 32942044 | Cell Mol Gastroenterol Hepatol | Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner. | 2020 | Details |
A06292 | 32939643 | Biol Trace Elem Res | Zinc Supplementation and Strength Exercise in Rats with Type 2 Diabetes: Akt and PTP1B Phosphorylation in Nonalcoholic Fatty Liver. | 2020 | Details |
A06297 | 32937194 | Mol Metab | Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis. | 2020 | Details |
A06300 | 32936098 | J R Coll Physicians Edinb | Diagnosis and management of fatty liver. | 2020 | Details |
A06301 | 32936063 | J Am Coll Nutr | Correlating Circulating Vitamin D3 with Aspects of the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in Healthy Female Volunteers. | 2020 | Details |
A06305 | 32934691 | Exp Ther Med | Abnormal metabolic processes involved in the pathogenesis of non-alcoholic fatty liver disease (Review). | 2020 | Details |
A06309 | 32933722 | Tissue Cell | Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats. | 2020 | Details |
A06316 | 32932174 | J Trace Elem Med Biol | The effects of zinc supplementation on metabolic profile and oxidative stress in overweight/obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
A06318 | 32931733 | Cell | Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output. | 2020 | Details |
A06319 | 32930860 | Wien Klin Wochenschr | Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease. | 2020 | Details |
A06340 | 32923108 | Am J Cardiovasc Dis | Increased cardiovascular events and mortality in females with NAFLD: a meta-analysis. | 2020 | Details |
A06347 | 32920973 | Mol Nutr Food Res | Dietary Rapeseed Oil Supplementation Reduces Hepatic Steatosis in Obese Men-A Randomized Controlled Trial. | 2020 | Details |
A06354 | 32918763 | FASEB J | Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD. | 2020 | Details |
A06360 | 32916379 | Nutrition | Pleiotropic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats. | 2020 | Details |
A06362 | 32916011 | Liver Transpl | Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. | 2020 | Details |
A06368 | 32910776 | Diabetes Care | Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes. | 2020 | Details |
A06369 | 32910646 | J Med Chem | Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose. | 2020 | Details |
A06376 | 32907986 | J Lipid Res | Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice. | 2020 | Details |
A06382 | 32905826 | Toxicology | Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro. | 2020 | Details |
A06394 | 32896622 | Biochim Biophys Acta Mol Cell Biol Lipids | 12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats. | 2020 | Details |
A06403 | 32892365 | Aliment Pharmacol Ther | Circulating lipidomic alterations in obese and non-obese subjects with non-alcoholic fatty liver disease. | 2020 | Details |
A06405 | 32891697 | Biochimie | Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury? | 2020 | Details |
A06412 | 32888949 | Metabolism | Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice. | 2020 | Details |
A06413 | 32888948 | Physiol Behav | The effect of aerobic, resistance, and combined training on PPAR-α, SIRT1 gene expression, and insulin resistance in high-fat diet-induced NAFLD male rats. | 2020 | Details |
A06430 | 32883049 | Cells | A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology. | 2020 | Details |
A06437 | 32881925 | PLoS One | Exchanging dietary fat source with extra virgin olive oil does not prevent progression of diet-induced non-alcoholic fatty liver disease and insulin resistance. | 2020 | Details |
A06468 | 32868653 | Eur J Gastroenterol Hepatol | Predictive markers of nonalcoholic fatty liver disease in lean patients. A multinomial regression model and a 2k factorial analysis. | 2021 | Details |
A06479 | 32863886 | BioData Min | Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease. | 2020 | Details |
A06480 | 32863329 | Tohoku J Exp Med | Hybrid Training System Improves Insulin Resistance in Patients with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Pilot Study. | 2020 | Details |
A06485 | 32861753 | Gastrointest Endosc | Improvement in insulin resistance and estimated hepatic steatosis and fibrosis after endoscopic sleeve gastroplasty. | 2020 | Details |
A06490 | 32857176 | Eur J Nutr | Dietary intake of specific amino acids and liver status in subjects with nonalcoholic fatty liver disease: fatty liver in obesity (FLiO) study. | 2020 | Details |
A06491 | 32856978 | J Med Food | Fisetin Alleviates Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice. | 2020 | Details |
A06501 | 32850903 | Front Med (Lausanne) | Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis. | 2020 | Details |