Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06279 | 32943747 | Sci Rep | Difference in lifestyle and metabolic profile of non-alcoholic fatty liver disease with raised alanine amino-transferases between obese and non-overweight subjects. | 2020 | Details |
| A06281 | 32943651 | Sci Rep | Punica granatum L.-derived omega-5 nanoemulsion improves hepatic steatosis in mice fed a high fat diet by increasing fatty acid utilization in hepatocytes. | 2020 | Details |
| A06284 | 32942044 | Cell Mol Gastroenterol Hepatol | Liver Pyruvate Kinase Promotes NAFLD/NASH in Both Mice and Humans in a Sex-Specific Manner. | 2020 | Details |
| A06292 | 32939643 | Biol Trace Elem Res | Zinc Supplementation and Strength Exercise in Rats with Type 2 Diabetes: Akt and PTP1B Phosphorylation in Nonalcoholic Fatty Liver. | 2020 | Details |
| A06297 | 32937194 | Mol Metab | Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis. | 2020 | Details |
| A06300 | 32936098 | J R Coll Physicians Edinb | Diagnosis and management of fatty liver. | 2020 | Details |
| A06301 | 32936063 | J Am Coll Nutr | Correlating Circulating Vitamin D3 with Aspects of the Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in Healthy Female Volunteers. | 2020 | Details |
| A06305 | 32934691 | Exp Ther Med | Abnormal metabolic processes involved in the pathogenesis of non-alcoholic fatty liver disease (Review). | 2020 | Details |
| A06309 | 32933722 | Tissue Cell | Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats. | 2020 | Details |
| A06314 | 32932529 | Exp Clin Endocrinol Diabetes | Liver Expressed Antimicrobial Peptide 2 is Associated with Steatosis in Mice and Humans. | 2020 | Details |
| A06316 | 32932174 | J Trace Elem Med Biol | The effects of zinc supplementation on metabolic profile and oxidative stress in overweight/obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
| A06318 | 32931733 | Cell | Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output. | 2020 | Details |
| A06319 | 32930860 | Wien Klin Wochenschr | Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease. | 2020 | Details |
| A06340 | 32923108 | Am J Cardiovasc Dis | Increased cardiovascular events and mortality in females with NAFLD: a meta-analysis. | 2020 | Details |
| A06347 | 32920973 | Mol Nutr Food Res | Dietary Rapeseed Oil Supplementation Reduces Hepatic Steatosis in Obese Men-A Randomized Controlled Trial. | 2020 | Details |
| A06354 | 32918763 | FASEB J | Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD. | 2020 | Details |
| A06360 | 32916379 | Nutrition | Pleiotropic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats. | 2020 | Details |
| A06362 | 32916011 | Liver Transpl | Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. | 2020 | Details |
| A06368 | 32910776 | Diabetes Care | Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes. | 2020 | Details |
| A06369 | 32910646 | J Med Chem | Discovery of PF-06835919: A Potent Inhibitor of Ketohexokinase (KHK) for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose. | 2020 | Details |
| A06376 | 32907986 | J Lipid Res | Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice. | 2020 | Details |
| A06382 | 32905826 | Toxicology | Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro. | 2020 | Details |
| A06394 | 32896622 | Biochim Biophys Acta Mol Cell Biol Lipids | 12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats. | 2020 | Details |
| A06403 | 32892365 | Aliment Pharmacol Ther | Circulating lipidomic alterations in obese and non-obese subjects with non-alcoholic fatty liver disease. | 2020 | Details |
| A06405 | 32891697 | Biochimie | Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury? | 2020 | Details |
| A06412 | 32888949 | Metabolism | Hrd1-mediated ACLY ubiquitination alleviate NAFLD in db/db mice. | 2020 | Details |
| A06413 | 32888948 | Physiol Behav | The effect of aerobic, resistance, and combined training on PPAR-α, SIRT1 gene expression, and insulin resistance in high-fat diet-induced NAFLD male rats. | 2020 | Details |
| A06430 | 32883049 | Cells | A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology. | 2020 | Details |
| A06436 | 32882372 | J Hepatol | rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis. | 2020 | Details |
| A06437 | 32881925 | PLoS One | Exchanging dietary fat source with extra virgin olive oil does not prevent progression of diet-induced non-alcoholic fatty liver disease and insulin resistance. | 2020 | Details |
| A06440 | 32880477 | Arch Physiol Biochem | High sugar but not high fat diet consumption induces hepatic metabolic disruption and up-regulation of mitochondrial fission-associated protein Drp1 in a model of moderate obesity. | 2020 | Details |
| A06467 | 32868684 | Curr Opin Clin Nutr Metab Care | Dietary protein intake and obesity-associated cardiometabolic function. | 2020 | Details |
| A06468 | 32868653 | Eur J Gastroenterol Hepatol | Predictive markers of nonalcoholic fatty liver disease in lean patients. A multinomial regression model and a 2k factorial analysis. | 2021 | Details |
| A06479 | 32863886 | BioData Min | Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease. | 2020 | Details |
| A06480 | 32863329 | Tohoku J Exp Med | Hybrid Training System Improves Insulin Resistance in Patients with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Pilot Study. | 2020 | Details |
| A06483 | 32862731 | Int J Food Sci Nutr | Dietary calamondin supplementation slows the progression of non-alcoholic fatty liver disease in C57BL/6 mice fed a high-fat diet. | 2020 | Details |
| A06485 | 32861753 | Gastrointest Endosc | Improvement in insulin resistance and estimated hepatic steatosis and fibrosis after endoscopic sleeve gastroplasty. | 2020 | Details |
| A06490 | 32857176 | Eur J Nutr | Dietary intake of specific amino acids and liver status in subjects with nonalcoholic fatty liver disease: fatty liver in obesity (FLiO) study. | 2020 | Details |
| A06491 | 32856978 | J Med Food | Fisetin Alleviates Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice. | 2020 | Details |
| A06501 | 32850903 | Front Med (Lausanne) | Insights Into Extracellular Vesicles as Biomarker of NAFLD Pathogenesis. | 2020 | Details |
| A06506 | 32849314 | Front Endocrinol (Lausanne) | Fructose Consumption During Pregnancy Influences Milk Lipid Composition and Offspring Lipid Profiles in Guinea Pigs. | 2020 | Details |
| A06509 | 32849276 | Front Endocrinol (Lausanne) | Ceramide Synthases Are Attractive Drug Targets for Treating Metabolic Diseases. | 2020 | Details |
| A06523 | 32841326 | J Clin Endocrinol Metab | Nonalcoholic Fatty Liver Disease and Estimated Insulin Resistance in Obese Youth: A Mendelian Randomization Analysis. | 2020 | Details |
| A06535 | 32833701 | Curr Opin Clin Nutr Metab Care | Lifestyle interventions affecting hepatic fatty acid metabolism. | 2020 | Details |
| A06538 | 32833043 | Arch Toxicol | A novel model of non-alcoholic steatohepatitis with fibrosis and carcinogenesis in connexin 32 dominant-negative transgenic rats. | 2020 | Details |
| A06539 | 32832560 | J Diabetes Res | The Intricate Relationship between Type 2 Diabetes Mellitus (T2DM), Insulin Resistance (IR), and Nonalcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A06544 | 32832391 | J Clin Transl Hepatol | Effect of Exercise on NAFLD and Its Risk Factors: Comparison of Moderate versus Low Intensity Exercise. | 2020 | Details |
| A06545 | 32831555 | J Family Community Med | Prevalence and risk factors for nonalcoholic fatty liver disease in obese children in rural Punjab, India. | 2020 | Details |
| A06551 | 32828745 | Clin Res Hepatol Gastroenterol | Myosteatosis in nonalcoholic fatty liver disease: An exploratory study. | 2020 | Details |
| A06561 | 32824723 | Int J Mol Sci | Hypothyroidism-Induced Nonalcoholic Fatty Liver Disease (HIN): Mechanisms and Emerging Therapeutic Options. | 2020 | Details |
| A06564 | 32824337 | Int J Mol Sci | History of Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06566 | 32824177 | Nutrients | Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review. | 2020 | Details |
| A06569 | 32823621 | Nutrients | Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease-A Meta-Analysis. | 2020 | Details |
| A06577 | 32821738 | J Lipid Atheroscler | Hepatic Expression of the Serine Palmitoyltransferase Subunit Sptlc2 Reduces Lipid Droplets in the Liver by Activating VLDL Secretion. | 2020 | Details |
| A06578 | 32821721 | J Lipid Atheroscler | Ceramides: Nutrient Signals that Drive Hepatosteatosis. | 2019 | Details |
| A06581 | 32821071 | World J Gastroenterol | Helicobacter pylori infection: Beyond gastric manifestations. | 2020 | Details |
| A06586 | 32819566 | Biochem Biophys Res Commun | Genetic ablation of Fas-activated serine/threonine kinase ameliorates obesity-related hepatic glucose and lipid metabolic disorders via sirtuin-1 signaling. | 2020 | Details |
| A06592 | 32815965 | Food Funct | A multi-targeting strategy to ameliorate high-fat-diet- and fructose-induced (western diet-induced) non-alcoholic fatty liver disease (NAFLD) with supplementation of a mixture of legume ethanol extracts. | 2020 | Details |
| A06600 | 32812775 | Am J Physiol Gastrointest Liver Physiol | Duodenal-jejunal bypass improves nonalcoholic fatty liver disease independently of weight loss in rodents with diet-induced obesity. | 2020 | Details |
| A06604 | 32810900 | Liver Int | Liver steatosis is highly prevalent and is associated with metabolic risk factors and liver fibrosis in adult patients with type 1 Gaucher disease. | 2020 | Details |
| A06608 | 32810487 | Metabolism | Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease. | 2020 | Details |
| A06612 | 32808824 | Can J Physiol Pharmacol | Intricacies of the endothelin system in human obesity: role in the development of complications and potential as a therapeutic target. | 2020 | Details |
| A06613 | 32808114 | J Physiol Biochem | Potential roles of bone morphogenetic protein-9 in glucose and lipid homeostasis. | 2020 | Details |
| A06619 | 32805210 | Chem Biol Interact | High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms. | 2020 | Details |
| A06631 | 32800834 | Life Sci | High fructose intake and the route towards cardiometabolic diseases. | 2020 | Details |
| A06649 | 32795119 | Metab Syndr Relat Disord | Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06653 | 32792584 | Sci Rep | Administration of small-molecule guanabenz acetate attenuates fatty liver and hyperglycemia associated with obesity. | 2020 | Details |
| A06654 | 32791802 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of non-alcoholic fatty liver disease in postmenopausal women]. | 2020 | Details |
| A06658 | 32791578 | Clin Mol Hepatol | Beneficial effect of anti-diabetic drugs for nonalcoholic fatty liver disease. | 2020 | Details |
| A06660 | 32791310 | Diabetes Metab | Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes. | 2020 | Details |
| A06662 | 32790863 | Endocrinology | DPP-4 Inhibition with Anagliptin Reduces Lipotoxicity-Induced Insulin Resistance and Steatohepatitis in Male Mice. | 2020 | Details |
| A06667 | 32788075 | Surg Obes Relat Dis | Prevalence of NASH/NAFLD in people with obesity who are currently classified as metabolically healthy. | 2020 | Details |
| A06672 | 32785111 | J Clin Med | Metabolic Footprint, towards Understanding Type 2 Diabetes beyond Glycemia. | 2020 | Details |
| A06675 | 32785012 | Int J Mol Sci | Glucagon-Like Peptide-1 Receptor Agonist Prevented the Progression of Hepatocellular Carcinoma in a Mouse Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06676 | 32784205 | BMJ Open Gastroenterol | Association of non-alcoholic fatty liver disease and polycystic ovarian syndrome. | 2020 | Details |
| A06682 | 32781739 | Nutrients | The Root of Polygonum multiflorum Thunb. Alleviates Non-Alcoholic Steatosis and Insulin Resistance in High Fat Diet-Fed Mice. | 2020 | Details |
| A06690 | 32779505 | J Am Heart Assoc | Effects of Epeleuton, a Novel Synthetic Second-Generation n-3 Fatty Acid, on Non-Alcoholic Fatty Liver Disease, Triglycerides, Glycemic Control, and Cardiometabolic and Inflammatory Markers. | 2020 | Details |
| A06694 | 32777482 | Biochim Biophys Acta Mol Cell Biol Lipids | Angiopoietin-like protein 3, an emerging cardiometabolic therapy target with systemic and cell-autonomous functions. | 2020 | Details |
| A06704 | 32775098 | Cureus | Vitamin E as an Adjuvant Treatment for Non-alcoholic Fatty Liver Disease in Adults: A Systematic Review of Randomized Controlled Trials. | 2020 | Details |
| A06709 | 32774148 | Mediators Inflamm | Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways. | 2020 | Details |
| A06710 | 32773176 | HPB (Oxford) | Cholecystectomy as a risk factor for non-alcoholic fatty liver disease development. | 2020 | Details |
| A06713 | 32772909 | Comb Chem High Throughput Screen | Evaluation of Insulin Resistance Induced Brain Tissue Dysfunction in Obese Dams and their Neonates: Role of Ipriflavone Amelioration. | 2021 | Details |
| A06715 | 32772323 | J Endocrinol Invest | Testosterone treatment is associated with reduced adipose tissue dysfunction and nonalcoholic fatty liver disease in obese hypogonadal men. | 2020 | Details |
| A06716 | 32771802 | Atherosclerosis | Serum lipoprotein(a) levels and insulin resistance have opposite effects on fatty liver disease. | 2020 | Details |
| A06717 | 32771373 | Peptides | Liraglutide ameliorates lipotoxicity-induced inflammation through the mTORC1 signalling pathway. | 2020 | Details |
| A06722 | 32769877 | Medicine (Baltimore) | Protective effect of probiotics in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06725 | 32768394 | Ann Endocrinol (Paris) | Impact of aerobic training with and without whole-body vibration training on metabolic features and quality of life in non-alcoholic fatty liver disease patients. | 2020 | Details |
| A06731 | 32766474 | Hepatol Commun | Mortality of NAFLD According to the Body Composition and Presence of Metabolic Abnormalities. | 2020 | Details |
| A06733 | 32766472 | Hepatol Commun | Genome-Wide Association Study of Liver Fat: The Multiethnic Cohort Adiposity Phenotype Study. | 2020 | Details |
| A06747 | 32762395 | J Int Med Res | Circulating IGFBP-2 levels are inversely associated with the incidence of nonalcoholic fatty liver disease: A cohort study. | 2020 | Details |
| A06751 | 32759940 | Nutr Diabetes | Neohesperidin enhances PGC-1α-mediated mitochondrial biogenesis and alleviates hepatic steatosis in high fat diet fed mice. | 2020 | Details |
| A06752 | 32759852 | Int J Mol Sci | Effective Combination Therapy of Angiotensin-II Receptor Blocker and Rifaximin for Hepatic Fibrosis in Rat Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06756 | 32758573 | Eur J Pharmacol | Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways. | 2020 | Details |
| A06759 | 32757283 | Fundam Clin Pharmacol | Protective effect of fenofibrate against high-fat-high-fructose diet induced non-obese NAFLD in rats. | 2020 | Details |
| A06762 | 32756704 | Food Funct | Recombinant human lactoferrin attenuates the progression of hepatosteatosis and hepatocellular death by regulating iron and lipid homeostasis in ob/ob mice. | 2020 | Details |
| A06764 | 32756082 | Medicine (Baltimore) | Efficacy of vitamin D supplement in children with nonalcoholic fatty liver disease: A protocol for systematic review and meta-analysis. | 2020 | Details |
| A06766 | 32755310 | Am J Physiol Gastrointest Liver Physiol | The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2020 | Details |
| A06767 | 32754976 | Mol Nutr Food Res | Metabolic Inflammation in Obesity-At the Crossroads between Fatty Acid and Cholesterol Metabolism. | 2020 | Details |
| A06775 | 32751794 | Int J Mol Sci | Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice. | 2020 | Details |
| A06776 | 32751772 | Nutrients | Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity. | 2020 | Details |