Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12613 | 30363947 | Oxid Med Cell Longev | Treatment of NASH with Antioxidant Therapy: Beneficial Effect of Red Cabbage on Type 2 Diabetic Rats. | 2018 | Details |
| A12626 | 30360467 | Int J Mol Sci | Arachidonic Acid Metabolites in Cardiovascular and Metabolic Diseases. | 2018 | Details |
| A12627 | 30360449 | Int J Mol Sci | Novel Transcriptional Mechanisms for Regulating Metabolism by Thyroid Hormone. | 2018 | Details |
| A12631 | 30359371 | PLoS One | N-substituted phenylbenzamides of the niclosamide chemotype attenuate obesity related changes in high fat diet fed mice. | 2018 | Details |
| A12633 | 30358115 | Liver Transpl | Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. | 2019 | Details |
| A12635 | 30357769 | Semin Liver Dis | Unfolded Protein Response Sensors in Hepatic Lipid Metabolism and Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12640 | 30355361 | Lipids Health Dis | Sleeve gastrectomy attenuates high fat diet-induced non-alcoholic fatty liver disease. | 2018 | Details |
| A12641 | 30353682 | J Diabetes Investig | Serum 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid is associated with lipid profiles and might protect against non-alcoholic fatty liver disease in Chinese individuals. | 2018 | Details |
| A12645 | 30352176 | Dev Cell | Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. | 2018 | Details |
| A12657 | 30343673 | Biol Sex Differ | Tissue-specific pathways and networks underlying sexual dimorphism in non-alcoholic fatty liver disease. | 2018 | Details |
| A12659 | 30341767 | Hepatology | Liraglutide, Sitagliptin, and Insulin Glargine Added to Metformin: The Effect on Body Weight and Intrahepatic Lipid in Patients With Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12662 | 30340105 | Int Immunopharmacol | Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism. | 2018 | Details |
| A12677 | 30333571 | Sci Rep | Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver. | 2018 | Details |
| A12684 | 30328034 | Biol Trace Elem Res | Effect of Duration of Exposure to Fluoride and Type of Diet on Lipid Parameters and De Novo Lipogenesis. | 2018 | Details |
| A12693 | 30324559 | Cell Biochem Biophys | Melatonin Modulates lipid Metabolism in HepG2 Cells Cultured in High Concentrations of Oleic Acid: AMPK Pathway Activation may Play an Important Role. | 2018 | Details |
| A12714 | 30317781 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of stearoyl-CoA desaturase-1 on obesity and non-alcoholic fatty liver disease Abstract]. | 2018 | Details |
| A12716 | 30317775 | Zhonghua Gan Zang Bing Za Zhi | [Establishment of zebrafish model for non-alcoholic steatohepatitis]. | 2018 | Details |
| A12719 | 30316865 | EBioMedicine | Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice. | 2018 | Details |
| A12724 | 30315461 | Methods Mol Biol | Measuring Human Lipid Metabolism Using Deuterium Labeling: In Vivo and In Vitro Protocols. | 2019 | Details |
| A12732 | 30312631 | Toxicol Appl Pharmacol | Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes. | 2018 | Details |
| A12734 | 30312023 | Anat Rec (Hoboken) | Role of MicroRNAs in the Development of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12747 | 30305244 | Biochim Biophys Acta Mol Cell Biol Lipids | Intake of stigmasterol and β-sitosterol alters lipid metabolism and alleviates NAFLD in mice fed a high-fat western-style diet. | 2018 | Details |
| A12754 | 30300671 | Biochim Biophys Acta Mol Basis Dis | Vitamin E alleviates non-alcoholic fatty liver disease in phosphatidylethanolamine N-methyltransferase deficient mice. | 2018 | Details |
| A12756 | 30300287 | Transplantation | Nonalcoholic Fatty Liver Disease: Basic Pathogenetic Mechanisms in the Progression From NAFLD to NASH. | 2019 | Details |
| A12757 | 30300140 | J Clin Invest | Gα12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. | 2018 | Details |
| A12762 | 30298748 | Am J Chin Med | Beneficial Effects of Korean Red Ginseng in the Progression of Non-Alcoholic Steatohepatitis via FABP4 Modulation. | 2018 | Details |
| A12770 | 30295789 | Endocrinology | Adult-Onset Hepatocyte GH Resistance Promotes NASH in Male Mice, Without Severe Systemic Metabolic Dysfunction. | 2018 | Details |
| A12772 | 30294300 | Front Endocrinol (Lausanne) | Developmental Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether Permanently Alters Blood-Liver Balance of Lipids in Male Mice. | 2018 | Details |
| A12784 | 30288689 | J Physiol Biochem | Agaricus bisporus supplementation reduces high-fat diet-induced body weight gain and fatty liver development. | 2018 | Details |
| A12802 | 30282694 | Sci Transl Med | An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo. | 2018 | Details |
| A12803 | 30281809 | Hepatology | LXRα Promotes Hepatosteatosis in Part Through Activation of MicroRNA-378 Transcription and Inhibition of Ppargc1β Expression. | 2019 | Details |
| A12806 | 30275422 | Int J Mol Sci | Hepatoprotective Effect of Loquat Leaf Flavonoids in PM2.5-Induced Non-Alcoholic Fatty Liver Disease via Regulation of IRs-1/Akt and CYP2E1/JNK Pathways. | 2018 | Details |
| A12815 | 30271746 | J Clin Transl Hepatol | The Genetics of Clinical Liver Diseases: Insight into the TM6SF2 E167K Variant. | 2018 | Details |
| A12827 | 30266038 | Br J Pharmacol | Diethyldithiocarbamate, an anti-abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress. | 2018 | Details |
| A12833 | 30262292 | J Trace Elem Med Biol | Low hair copper concentration is related to a high risk of nonalcoholic fatty liver disease in adults. | 2018 | Details |
| A12836 | 30261661 | Int J Mol Sci | Fc Gamma Receptor IIb Expressed in Hepatocytes Promotes Lipid Accumulation and Gluconeogenesis. | 2018 | Details |
| A12838 | 30261289 | Biochim Biophys Acta Mol Basis Dis | Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans. | 2018 | Details |
| A12840 | 30260782 | Turk J Gastroenterol | Can pancreatic steatosis affect exocrine functions of pancreas? | 2018 | Details |
| A12854 | 30256948 | Hum Mol Genet | Bezafibrate induces autophagy and improves hepatic lipid metabolism in glycogen storage disease type Ia. | 2019 | Details |
| A12856 | 30254132 | Dis Model Mech | A nonalcoholic fatty liver disease model in human induced pluripotent stem cell-derived hepatocytes, created by endoplasmic reticulum stress-induced steatosis. | 2018 | Details |
| A12870 | 30248445 | Free Radic Biol Med | Maternal perinatal calorie restriction temporally regulates the hepatic autophagy and redox status in male rat. | 2018 | Details |
| A12872 | 30248234 | Liver Int | Hepatic fat as clinical outcome and therapeutic target for nonalcoholic fatty liver disease. | 2018 | Details |
| A12877 | 30246507 | Helicobacter | Helicobacter pylori and non-alcoholic fatty liver disease: A new enigma? | 2018 | Details |
| A12880 | 30244573 | J Agric Food Chem | Black Sesame Seeds Ethanol Extract Ameliorates Hepatic Lipid Accumulation, Oxidative Stress, and Insulin Resistance in Fructose-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12883 | 30242180 | Sci Rep | HIF-1-dependent lipin1 induction prevents excessive lipid accumulation in choline-deficient diet-induced fatty liver. | 2018 | Details |
| A12885 | 30241944 | Biochem Biophys Res Commun | Spermidine ameliorates non-alcoholic fatty liver disease through regulating lipid metabolism via AMPK. | 2018 | Details |
| A12899 | 30235452 | Cell Physiol Biochem | Fisetin Protects Against Hepatic Steatosis Through Regulation of the Sirt1/AMPK and Fatty Acid β-Oxidation Signaling Pathway in High-Fat Diet-Induced Obese Mice. | 2018 | Details |
| A12930 | 30221679 | Int J Mol Med | Anti-obesity and fatty liver-preventing activities of Lonicera caerulea in high-fat diet-fed mice. | 2018 | Details |
| A12938 | 30217154 | BMC Endocr Disord | Estrogen receptor 1 gene polymorphisms are associated with metabolic syndrome in postmenopausal women in China. | 2018 | Details |
| A12956 | 30209324 | Sci Rep | Systems pharmacology-based exploration reveals mechanisms of anti-steatotic effects of Jiang Zhi Granule on non-alcoholic fatty liver disease. | 2018 | Details |
| A12958 | 30208604 | Molecules | Hexanoic, Octanoic and Decanoic Acids Promote Basal and Insulin-Induced Phosphorylation of the Akt-mTOR Axis and a Balanced Lipid Metabolism in the HepG2 Hepatoma Cell Line. | 2018 | Details |
| A12960 | 30208301 | Food Chem Toxicol | Trigonelline prevents high cholesterol and high fat diet induced hepatic lipid accumulation and lipo-toxicity in C57BL/6J mice, via restoration of hepatic autophagy. | 2018 | Details |
| A12963 | 30206707 | Amino Acids | Regulation of glucose and lipid metabolism by the pancreatic and extra-pancreatic actions of taurine. | 2018 | Details |
| A12964 | 30206377 | Sci Rep | Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. | 2018 | Details |
| A12983 | 30197273 | J Clin Lipidol | Effects of free omega-3 carboxylic acids and fenofibrate on liver fat content in patients with hypertriglyceridemia and non-alcoholic fatty liver disease: A double-blind, randomized, placebo-controlled study. | 2018 | Details |
| A12985 | 30196282 | Cell Physiol Biochem | Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF. | 2018 | Details |
| A12991 | 30193066 | J Agric Food Chem | Insecticide Exposure and Development of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12993 | 30191499 | Dig Dis Sci | Silybin Alleviates Hepatic Steatosis and Fibrosis in NASH Mice by Inhibiting Oxidative Stress and Involvement with the Nf-κB Pathway. | 2018 | Details |
| A13020 | 30178600 | Diabetes Obes Metab | Evaluation of the effects of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on hepatic steatosis and fibrosis using transient elastography in patients with type 2 diabetes and non-alcoholic fatty liver disease. | 2018 | Details |
| A13034 | 30171718 | J Cell Biochem | PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes. | 2018 | Details |
| A13037 | 30171034 | Dis Model Mech | Idebenone and coenzyme Q10 are novel PPARα/γ ligands, with potential for treatment of fatty liver diseases. | 2018 | Details |
| A13042 | 30168806 | J Clin Invest | Mitochondrial role in the neonatal predisposition to developing nonalcoholic fatty liver disease. | 2018 | Details |
| A13049 | 31807367 | Liver Res | Regulation of the homeostasis of hepatic endoplasmic reticulum and cytochrome P450 enzymes by autophagy. | 2018 | Details |
| A13055 | 30160281 | Food Funct | Freshwater clam extract reduces liver injury by lowering cholesterol accumulation, improving dysregulated cholesterol synthesis and alleviating inflammation in high-fat, high-cholesterol and cholic acid diet-induced steatohepatitis in mice. | 2018 | Details |
| A13059 | 30158201 | J Lipid Res | Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice. | 2018 | Details |
| A13065 | 30154499 | Sci Rep | The PPARα Agonist Fenofibrate Prevents Formation of Protein Aggregates (Mallory-Denk bodies) in a Murine Model of Steatohepatitis-like Hepatotoxicity. | 2018 | Details |
| A13066 | 30154417 | Cell Death Dis | JAZF1 ameliorates age and diet-associated hepatic steatosis through SREBP-1c -dependent mechanism. | 2018 | Details |
| A13067 | 30154382 | Int J Mol Sci | Flavonones from Penthorum chinense Ameliorate Hepatic Steatosis by Activating the SIRT1/AMPK Pathway in HepG2 Cells. | 2018 | Details |
| A13069 | 30153476 | Free Radic Biol Med | Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration. | 2018 | Details |
| A13073 | 30150602 | Molecules | Deoxyschizandrin Loaded Liposomes on the Suppression Lipid Accumulation in 3T3-L1 Adipocytes. | 2018 | Details |
| A13079 | 30145577 | Ann Hepatol | Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats. | 2018 | Details |
| A13095 | 30140371 | Oxid Med Cell Longev | Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway. | 2018 | Details |
| A13096 | 30140364 | Oxid Med Cell Longev | NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ. | 2018 | Details |
| A13108 | 30135326 | Biol Pharm Bull | Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation. | 2018 | Details |
| A13137 | 30120929 | Toxicology | Modulation of xenobiotic nuclear receptors in high-fat diet induced non-alcoholic fatty liver disease. | 2018 | Details |
| A13147 | 30115876 | Molecules | Hepatoprotective Effects of MHY3200 on High-Fat, Diet-Induced, Non-Alcoholic Fatty Liver Disease in Rats. | 2018 | Details |
| A13161 | 30109054 | R Soc Open Sci | Synergistic effect of eicosapentaenoic acid-enriched phospholipids and sea cucumber saponin on orotic acid-induced non-alcoholic fatty liver disease in rats. | 2018 | Details |
| A13164 | 30105660 | Obes Surg | Small Intestinal Length Associates with Serum Triglycerides Before and After LRYGB. | 2018 | Details |
| A13169 | 30103390 | Nutrients | Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice. | 2018 | Details |
| A13174 | 30100243 | Mol Metab | Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context. | 2018 | Details |
| A13177 | 30099414 | Wiad Lek | Pathogenesis of insulin resistance in pregnant women with obesity. | 2018 | Details |
| A13181 | 30098126 | Diabetes Obes Metab | The effects of dietary supplementation with inulin and inulin-propionate ester on hepatic steatosis in adults with non-alcoholic fatty liver disease. | 2018 | Details |
| A13199 | 30089858 | Lab Invest | Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis. | 2018 | Details |
| A13215 | 30079055 | Front Microbiol | Genetically Obese Human Gut Microbiota Induces Liver Steatosis in Germ-Free Mice Fed on Normal Diet. | 2018 | Details |
| A13230 | 30073766 | Diabetes Obes Metab | Liraglutide treatment improves postprandial lipid metabolism and cardiometabolic risk factors in humans with adequately controlled type 2 diabetes: A single-centre randomized controlled study. | 2018 | Details |
| A13234 | 30071259 | Biochimie | Sphingolipid metabolism in non-alcoholic fatty liver diseases. | 2018 | Details |
| A13239 | 30068869 | Biol Pharm Bull | Molybdate Attenuates Lipid Accumulation in the Livers of Mice Fed a Diet Deficient in Methionine and Choline. | 2018 | Details |
| A13258 | 30060808 | Adv Cancer Res | Sphingolipids at the Crossroads of NAFLD and Senescence. | 2018 | Details |
| A13262 | 30060507 | Nutrients | Luteolin-Enriched Artichoke Leaf Extract Alleviates the Metabolic Syndrome in Mice with High-Fat Diet-Induced Obesity. | 2018 | Details |
| A13265 | 31949816 | Int J Clin Exp Pathol | HCMV-encoded IE2 promotes NAFLD progression by up-regulation of SREBP1c expression in UL122 genetically modified mice. | 2018 | Details |
| A13266 | 30060179 | J Clin Endocrinol Metab | Hepatic Steatosis Is Associated With Adverse Molecular Signatures in Subjects Without Diabetes. | 2018 | Details |
| A13271 | 30057681 | Oxid Med Cell Longev | Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT. | 2018 | Details |
| A13276 | 30055626 | Lipids Health Dis | Resveratrol ameliorates maternal and post-weaning high-fat diet-induced nonalcoholic fatty liver disease via renin-angiotensin system. | 2018 | Details |
| A13283 | 30051965 | Mol Nutr Food Res | Galactomannan More than Pectin Exacerbates Liver Injury in Mice Fed with High-Fat, High-Cholesterol Diet. | 2018 | Details |
| A13293 | 30047462 | Chin J Nat Med | Mori Cortex extract ameliorates nonalcoholic fatty liver disease (NAFLD) and insulin resistance in high-fat-diet/streptozotocin-induced type 2 diabetes in rats. | 2018 | Details |
| A13301 | 30042157 | J Lipid Res | Mitochondrial dysfunction-related lipid changes occur in nonalcoholic fatty liver disease progression. | 2018 | Details |
| A13307 | 30038487 | Drug Des Devel Ther | Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis. | 2018 | Details |
| A13308 | 30038464 | World J Gastroenterol | Pathogenesis of non-alcoholic fatty liver disease in children and adolescence: From "two hit theory" to "multiple hit model". | 2018 | Details |
| A13310 | 30037134 | Int J Mol Sci | High-Content Screening of a Taiwanese Indigenous Plant Extract Library Identifies Syzygium simile leaf Extract as an Inhibitor of Fatty Acid Uptake. | 2018 | Details |
| A13311 | 30037123 | Nutrients | Dietary Fibre as a Unifying Remedy for the Whole Spectrum of Obesity-Associated Cardiovascular Risk. | 2018 | Details |