Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A12835 | 30261763 | Expert Rev Gastroenterol Hepatol | An update on the recent advances in antifibrotic therapy. | 2018 | Details |
| A12841 | 30259536 | Hepatology | Angiopoietin-2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A12845 | 30258096 | Lab Invest | Activation of brown adipose tissue enhances the efficacy of caloric restriction for treatment of nonalcoholic steatohepatitis. | 2018 | Details |
| A12846 | 30258086 | Exp Mol Med | Role of miR-223 in the pathophysiology of liver diseases. | 2018 | Details |
| A12849 | 30257633 | Med J Aust | The gut microbiota: cause and cure of gut diseases. | 2018 | Details |
| A12861 | 30252139 | Lipids | Folic Acid Supplementation Attenuates Chronic Hepatic Inflammation in High-Fat Diet Fed Mice. | 2018 | Details |
| A12866 | 30249972 | Diseases | The Role of Vitamin E in the Treatment of NAFLD. | 2018 | Details |
| A12877 | 30246507 | Helicobacter | Helicobacter pylori and non-alcoholic fatty liver disease: A new enigma? | 2018 | Details |
| A12886 | 30241896 | Cytokine | Role of hepatic stellate cell (HSC)-derived cytokines in hepatic inflammation and immunity. | 2018 | Details |
| A12891 | 30239004 | J Cell Physiol | Cholesterol burden in the liver induces mitochondrial dynamic changes and resistance to apoptosis. | 2018 | Details |
| A12895 | 30236852 | Biomed Pharmacother | Protective effects of Kangxian ruangan capsule against nonalcoholic fatty liver disease fibrosis in rats induced by MCD diet. | 2018 | Details |
| A12896 | 30235843 | Medicines (Basel) | Effects of Shugan-Jianpi Recipe on the Expression of the p38 MAPK/NF-κB Signaling Pathway in the Hepatocytes of NAFLD Rats. | 2018 | Details |
| A12897 | 30235828 | Nutrients | Non-Alcoholic Fatty Liver Disease in Overweight Children: Role of Fructose Intake and Dietary Pattern. | 2018 | Details |
| A12903 | 30233587 | Front Immunol | Mucosal-Associated Invariant T Cells Improve Nonalcoholic Fatty Liver Disease Through Regulating Macrophage Polarization. | 2018 | Details |
| A12905 | 30231595 | Nutrients | Soybean Oil-Derived Poly-Unsaturated Fatty Acids Enhance Liver Damage in NAFLD Induced by Dietary Cholesterol. | 2018 | Details |
| A12909 | 30230967 | Annu Rev Pathol | Innate Immune Signaling in Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases. | 2018 | Details |
| A12923 | 30225267 | J Diabetes Res | Rosiglitazone Elicits an Adiponectin-Mediated Insulin-Sensitizing Action at the Adipose Tissue-Liver Axis in Otsuka Long-Evans Tokushima Fatty Rats. | 2018 | Details |
| A12928 | 30221912 | Minerva Med | Beneficial effects of probiotic combination with omega-3 fatty acids in NAFLD: a randomized clinical study. | 2018 | Details |
| A12929 | 30221732 | Mol Med Rep | Inhibition of CCL19 benefits non‑alcoholic fatty liver disease by inhibiting TLR4/NF‑κB‑p65 signaling. | 2018 | Details |
| A12933 | 30219279 | J Control Release | Therapeutic inhibition of spleen tyrosine kinase in inflammatory macrophages using PLGA nanoparticles for the treatment of non-alcoholic steatohepatitis. | 2018 | Details |
| A12934 | 30219068 | Lipids Health Dis | Localization of fat depots and cardiovascular risk. | 2018 | Details |
| A12936 | 30218679 | J Hepatol | MicroRNA-378 promotes hepatic inflammation and fibrosis via modulation of the NF-κB-TNFα pathway. | 2018 | Details |
| A12939 | 30217048 | Nutrients | Aerobic Physical Activity and a Low Glycemic Diet Reduce the AA/EPA Ratio in Red Blood Cell Membranes of Patients with NAFLD. | 2018 | Details |
| A12947 | 30213555 | Gastroenterology | Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice. | 2018 | Details |
| A12949 | 30213101 | Int J Mol Sci | NLRP3 Inflammasome and IL-33: Novel Players in Sterile Liver Inflammation. | 2018 | Details |
| A12963 | 30206707 | Amino Acids | Regulation of glucose and lipid metabolism by the pancreatic and extra-pancreatic actions of taurine. | 2018 | Details |
| A12964 | 30206377 | Sci Rep | Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model. | 2018 | Details |
| A12967 | 30205811 | BMC Med | An exploratory study examining how nano-liquid chromatography-mass spectrometry and phosphoproteomics can differentiate patients with advanced fibrosis and higher percentage collagen in non-alcoholic fatty liver disease. | 2018 | Details |
| A12972 | 30201879 | Diseases | Potential Therapeutic Benefits of Herbs and Supplements in Patients with NAFLD. | 2018 | Details |
| A12975 | 30200724 | Zhongguo Zhong Yao Za Zhi | [Effect of traditional Chinese medicine in inhibiting obesity and inflammatory diseases by regulating gut microbiota]. | 2018 | Details |
| A12976 | 30200715 | Zhongguo Zhong Yao Za Zhi | [Effect of Fuzi Lizhong decoction in reducing liver injury of rats with non-alcoholic fatty liver via activating AMPK and suppressing NF-κBp65 pathway]. | 2018 | Details |
| A12988 | 30194708 | Aliment Pharmacol Ther | Review article: drug-induced liver injury in the context of nonalcoholic fatty liver disease - a physiopathological and clinical integrated view. | 2018 | Details |
| A12990 | 30193922 | J Hepatol | Dietary exacerbation of metabolic stress leads to accelerated hepatic carcinogenesis in glycogen storage disease type Ia. | 2018 | Details |
| A12992 | 30192782 | PLoS One | Utility and variability of three non-invasive liver fibrosis imaging modalities to evaluate efficacy of GR-MD-02 in subjects with NASH and bridging fibrosis during a phase-2 randomized clinical trial. | 2018 | Details |
| A13026 | 30175257 | Anim Nutr | Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in mice. | 2018 | Details |
| A13031 | 30172659 | Clin Nutr | Marine omega-3 fatty acid supplementation in non-alcoholic fatty liver disease: Plasma proteomics in the randomized WELCOME* trial. | 2018 | Details |
| A13055 | 30160281 | Food Funct | Freshwater clam extract reduces liver injury by lowering cholesterol accumulation, improving dysregulated cholesterol synthesis and alleviating inflammation in high-fat, high-cholesterol and cholic acid diet-induced steatohepatitis in mice. | 2018 | Details |
| A13090 | 30142454 | Free Radic Biol Med | Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state. | 2018 | Details |
| A13096 | 30140364 | Oxid Med Cell Longev | NLRP3 Inflammasome Formation and Activation in Nonalcoholic Steatohepatitis: Therapeutic Target for Antimetabolic Syndrome Remedy FTZ. | 2018 | Details |
| A13098 | 30139548 | Cytokine | The role of IFN in the development of NAFLD and NASH. | 2018 | Details |
| A13102 | 30138466 | PLoS One | Correction: Association of inflammatory genes in obstructive sleep apnea and non alcoholic fatty liver disease in Asian Indians residing in north India. | 2018 | Details |
| A13103 | 30137403 | J Clin Endocrinol Metab | Ghrelin Reduces TNF-α-Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD. | 2019 | Details |
| A13106 | 30135638 | Cent Eur J Immunol | Changes in the immune system - the key to diagnostics and therapy of patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A13108 | 30135326 | Biol Pharm Bull | Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation. | 2018 | Details |
| A13124 | 30128963 | Curr Nutr Rep | Nutritional Ketosis for Weight Management and Reversal of Metabolic Syndrome. | 2018 | Details |
| A13129 | 30125542 | Am J Pathol | Toll-Like Receptor-7 Signaling Promotes Nonalcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice. | 2018 | Details |
| A13131 | 30123057 | Int J Med Sci | Effects of Chinese Medicinal Formula BNG-1 on Phosphodiesterase 3B Expression, Hepatic Steatosis, and Insulin Resistance in High Fat Diet-induced NAFLD Mice. | 2018 | Details |
| A13149 | 30114411 | Life Sci | C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis. | 2018 | Details |
| A13165 | 30105078 | Evid Based Complement Alternat Med | Chaihu-Shugan-San Decoction Modulates Intestinal Microbe Dysbiosis and Alleviates Chronic Metabolic Inflammation in NAFLD Rats via the NLRP3 Inflammasome Pathway. | 2018 | Details |
| A13168 | 30103942 | Cell Immunol | Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA release. | 2018 | Details |
| A13172 | 30102772 | Hepatology | Macrophage-Specific Hypoxia-Inducible Factor-1α Contributes to Impaired Autophagic Flux in Nonalcoholic Steatohepatitis. | 2019 | Details |
| A13185 | 30096384 | Life Sci | Gut inflammation exacerbates hepatic injury in the high-fat diet induced NAFLD mouse: Attention to the gut-vascular barrier dysfunction. | 2018 | Details |
| A13186 | 30096092 | Eur J Gastroenterol Hepatol | Rifaximin in nonalcoholic fatty liver disease: hit multiple targets with a single shot. | 2018 | Details |
| A13193 | 30092591 | Cell Physiol Biochem | Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice. | 2018 | Details |
| A13194 | 30091925 | J Proteome Res | Ron Receptor Signaling Ameliorates Hepatic Fibrosis in a Diet-Induced Nonalcoholic Steatohepatitis Mouse Model. | 2018 | Details |
| A13199 | 30089858 | Lab Invest | Iso-alpha acids from hops (Humulus lupulus) inhibit hepatic steatosis, inflammation, and fibrosis. | 2018 | Details |
| A13204 | 30086613 | Clin Mol Hepatol | Recent research trends and updates on nonalcoholic fatty liver disease. | 2018 | Details |
| A13205 | 30085339 | Int J Mol Med | Markers of activated inflammatory cells are associated with disease severity and intestinal microbiota in adults with non‑alcoholic fatty liver disease. | 2018 | Details |
| A13208 | 30083134 | Front Endocrinol (Lausanne) | Association of Nonalcoholic Fatty Liver Disease With Osteoporotic Fractures: A Cross-Sectional Retrospective Study of Chinese Individuals. | 2018 | Details |
| A13209 | 30083132 | Front Endocrinol (Lausanne) | Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis. | 2018 | Details |
| A13237 | 30070430 | Mol Nutr Food Res | Soyasaponins Reduce Inflammation and Improve Serum Lipid Profiles and Glucose Homeostasis in High Fat Diet-Induced Obese Mice. | 2018 | Details |
| A13244 | 30066228 | Infection | Endotoxinemia contributes to steatosis, insulin resistance and atherosclerosis in chronic hepatitis C: the role of pro-inflammatory cytokines and oxidative stress. | 2018 | Details |
| A13254 | 30063256 | Hepatology | Dual-Specificity Phosphatase 9 Protects Against Nonalcoholic Fatty Liver Disease in Mice Through ASK1 Suppression. | 2018 | Details |
| A13257 | 30060948 | Biochem Biophys Res Commun | Saxagliptin regulates M1/M2 macrophage polarization via CaMKKβ/AMPK pathway to attenuate NAFLD. | 2018 | Details |
| A13261 | 30060508 | Int J Mol Sci | Harmful Effects and Potential Benefits of Anti-Tumor Necrosis Factor (TNF)-α on the Liver. | 2018 | Details |
| A13270 | 30058778 | Hepatol Res | Clinicopathological investigation of steatohepatitic hepatocellular carcinoma: A multicenter study using immunohistochemical analysis of adenoma-related markers. | 2018 | Details |
| A13274 | 30056271 | Redox Biol | Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy. | 2018 | Details |
| A13275 | 30055803 | Biochem Biophys Res Commun | Autophagy is involved in acetylshikonin ameliorating non-alcoholic steatohepatitis through AMPK/mTOR pathway. | 2018 | Details |
| A13278 | 30054551 | Sci Rep | Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin. | 2018 | Details |
| A13279 | 30053055 | J Clin Endocrinol Metab | CXC Motif Ligand 16 Promotes Nonalcoholic Fatty Liver Disease Progression via Hepatocyte-Stellate Cell Crosstalk. | 2018 | Details |
| A13300 | 30042374 | Int J Mol Sci | Silibinin Ameliorates O-GlcNAcylation and Inflammation in a Mouse Model of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13305 | 30039136 | Food Funct | trans-Chalcone prevents insulin resistance and hepatic inflammation and also promotes hepatic cholesterol efflux in high-fat diet-fed rats: modulation of miR-34a-, miR-451-, and miR-33a-related pathways. | 2018 | Details |
| A13307 | 30038487 | Drug Des Devel Ther | Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis. | 2018 | Details |
| A13312 | 30037080 | Nutrients | Understanding the Impact of Dietary Cholesterol on Chronic Metabolic Diseases through Studies in Rodent Models. | 2018 | Details |
| A13314 | 30036865 | Cell Physiol Biochem | Cangju Qinggan Jiangzhi Decoction Reduces the Development of NonAlcoholic Steatohepatitis and Activation of Kupffer Cells. | 2018 | Details |
| A13315 | 30036479 | Mol Pharm | Diammonium Glycyrrhizinate Protects against Nonalcoholic Fatty Liver Disease in Mice through Modulation of Gut Microbiota and Restoration of Intestinal Barrier. | 2018 | Details |
| A13317 | 30034912 | Liver Res | FOXO transcription factors in non-alcoholic fatty liver disease. | 2017 | Details |
| A13318 | 30034633 | Oncotarget | Toll-like receptor 4: a target for chemoprevention of hepatocellular carcinoma in obesity and steatohepatitis. | 2018 | Details |
| A13319 | 30033779 | Expert Rev Gastroenterol Hepatol | Health benefits of Mediterranean diet in nonalcoholic fatty liver disease. | 2018 | Details |
| A13322 | 30032465 | Sleep Breath | Non-alcoholic fatty liver disease is an independent risk factor for inflammation in obstructive sleep apnea syndrome in obese Asian Indians. | 2018 | Details |
| A13325 | 30030460 | Sci Rep | Uncaria tomentosa improves insulin sensitivity and inflammation in experimental NAFLD. | 2018 | Details |
| A13330 | 30027532 | Hepatol Int | Linking the gut and liver: crosstalk between regulatory T cells and mucosa-associated invariant T cells. | 2018 | Details |
| A13334 | 30026731 | Front Endocrinol (Lausanne) | Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. | 2018 | Details |
| A13342 | 30024933 | PLoS One | miR-122 inhibition in a human liver organoid model leads to liver inflammation, necrosis, steatofibrosis and dysregulated insulin signaling. | 2018 | Details |
| A13348 | 30019185 | J Physiol Biochem | Cathepsin B inhibition ameliorates the non-alcoholic steatohepatitis through suppressing caspase-1 activation. | 2018 | Details |
| A13350 | 30018721 | Am J Transl Res | Activation of the CXCL16/CXCR6 pathway promotes lipid deposition in fatty livers of apolipoprotein E knockout mice and HepG2 cells. | 2018 | Details |
| A13358 | 30016770 | Dig Dis | Hepatoprotection by L-Ornithine L-Aspartate in Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
| A13363 | 30015859 | Int J Mol Med | Effect of celastrol on toll‑like receptor 4‑mediated inflammatory response in free fatty acid‑induced HepG2 cells. | 2018 | Details |
| A13364 | 30015675 | Curr Opin Lipidol | Non-parenchymal hepatic cell lipotoxicity and the coordinated progression of non-alcoholic fatty liver disease and atherosclerosis. | 2018 | Details |
| A13370 | 30013757 | Middle East J Dig Dis | Correlation between Serum Ferritin Level and Histopathological Disease Severity in Non-alcoholic Fatty Liver Disease. | 2018 | Details |
| A13376 | 30011790 | Int J Mol Sci | New Aspects of Lipotoxicity in Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13381 | 30009570 | Physiol Rep | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | 2018 | Details |
| A13382 | 30009361 | Folia Morphol (Warsz) | The differential effects of high-fat and high- -fructose diets on the liver of male albino rat and the proposed underlying mechanisms. | 2018 | Details |
| A13384 | 30006580 | Int J Obes (Lond) | Zinc alpha2 glycoprotein protects against obesity-induced hepatic steatosis. | 2018 | Details |
| A13391 | 30002817 | F1000Res | Recent advances in understanding liver fibrosis: bridging basic science and individualized treatment concepts. | 2018 | Details |
| A13396 | 30001365 | PLoS One | Association of inflammatory genes in obstructive sleep apnea and non alcoholic fatty liver disease in Asian Indians residing in north India. | 2018 | Details |
| A13406 | 29992631 | J Eur Acad Dermatol Venereol | Position statement for the management of comorbidities in psoriasis. | 2018 | Details |
| A13415 | 29989851 | Am J Physiol Endocrinol Metab | Saturated fatty acid combined with lipopolysaccharide stimulates a strong inflammatory response in hepatocytes in vivo and in vitro. | 2018 | Details |
| A13448 | 29969718 | Free Radic Biol Med | IRE1α aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells. | 2018 | Details |
| A13461 | 29961332 | J Agric Food Chem | Sodium Butyrate Ameliorates High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease through Peroxisome Proliferator-Activated Receptor α-Mediated Activation of β Oxidation and Suppression of Inflammation. | 2018 | Details |