Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A23378 | 23833274 | J Endocrinol | Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance. | 2013 | Details |
| A23381 | 23831119 | J Hepatol | Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells. | 2013 | Details |
| A23383 | 23829707 | Ups J Med Sci | Serum gamma glutamyl transferase and alanine transaminase concentrations predict endothelial dysfunction in patients with non-alcoholic steatohepatitis. | 2013 | Details |
| A23385 | 23828743 | Saudi J Gastroenterol | The role of endocannabinoids system in fatty liver disease and therapeutic potentials. | 2014 | Details |
| A23386 | 23827477 | Trends Endocrinol Metab | Non-alcoholic steatohepatitis: a microbiota-driven disease. | 2013 | Details |
| A23387 | 23826984 | Clin Sci (Lond) | Endothelial dysfunction in hyperandrogenic polycystic ovary syndrome is not explained by either obesity or ectopic fat deposition. | 2014 | Details |
| A23389 | 23826075 | PLoS One | Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice. | 2013 | Details |
| A23392 | 23820633 | Diabetologia | Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity. | 2013 | Details |
| A23396 | 23816341 | Diabetol Metab Syndr | Pleiotropic effects of rosuvastatin on the glucose metabolism and the subcutaneous and visceral adipose tissue behavior in C57Bl/6 mice. | 2013 | Details |
| A23397 | 23815500 | Antioxid Redox Signal | Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents? | 2013 | Details |
| A23398 | 23815295 | Aging Cell | Liver diseases and aging: friends or foes? | 2013 | Details |
| A23399 | 23814606 | Therap Adv Gastroenterol | Prospective histopathologic evaluation of lifestyle modification in nonalcoholic fatty liver disease: a randomized trial. | 2013 | Details |
| A23400 | 23813132 | Ann Hepatol | Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. | 2013 | Details |
| A23405 | 23808297 | Ter Arkh | [Metabolic correction of dyslipidemia in patients with nonalcoholic fatty liver disease as a new therapy policy]. | 2013 | Details |
| A23410 | 23805238 | PLoS One | High Fat Diet Induces Liver Steatosis and Early Dysregulation of Iron Metabolism in Rats. | 2013 | Details |
| A23417 | 23801829 | World J Gastroenterol | What about non-alcoholic fatty liver disease as a new criterion to define metabolic syndrome? | 2013 | Details |
| A23418 | 23800945 | J Gastroenterol | Bofutsushosan, a Japanese herbal (Kampo) medicine, attenuates progression of nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23423 | 23796801 | Gene | Associations of the PTEN -9C>G polymorphism with insulin sensitivity and central obesity in Chinese. | 2013 | Details |
| A23430 | 23792151 | Biochimie | Zonation of glucose and fatty acid metabolism in the liver: mechanism and metabolic consequences. | 2013 | Details |
| A23433 | 23790128 | J Hum Nutr Diet | Hypoadiponectinaemia in nonalcoholic fatty liver disease obese women is associated with infrequent intake of dietary sucrose and fatty foods. | 2013 | Details |
| A23440 | 23782071 | J Paediatr Child Health | Assessment of atherosclerosis in obese adolescents: positive correlation of mean platelet volume and carotid intima media thickness. | 2013 | Details |
| A23447 | 23772273 | World J Diabetes | Gastrointestinal complications of diabetes mellitus. | 2013 | Details |
| A23449 | 23770462 | Mol Cell Endocrinol | Hepatic energy metabolism in human diabetes mellitus, obesity and non-alcoholic fatty liver disease. | 2013 | Details |
| A23451 | 23770180 | J Am Coll Cardiol | Obstructive sleep apnea: a cardiometabolic risk in obesity and the metabolic syndrome. | 2013 | Details |
| A23459 | 23760677 | Diabetologia | A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid. | 2013 | Details |
| A23463 | 23758436 | Clin Sci (Lond) | Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice. | 2013 | Details |
| A23467 | 23754536 | Mol Med Rep | Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation. | 2013 | Details |
| A23470 | 23751754 | J Hepatol | From NAFLD in clinical practice to answers from guidelines. | 2013 | Details |
| A23474 | 23747246 | Cell Metab | Innate immune receptors: key regulators of metabolic disease progression. | 2013 | Details |
| A23475 | 23746214 | Clin Endocrinol (Oxf) | A comparison of cardiovascular risk indices in patients with polycystic ovary syndrome with and without coexisting nonalcoholic fatty liver disease. | 2013 | Details |
| A23476 | 23745619 | Metab Syndr Relat Disord | Nonalcoholic fatty liver disease and reduced serum vitamin D(3) levels. | 2013 | Details |
| A23479 | 23744740 | Am J Physiol Gastrointest Liver Physiol | CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism. | 2013 | Details |
| A23481 | 23742138 | J Agric Food Chem | Altered hepatic gene expression profiles associated with improved fatty liver, insulin resistance, and intestinal permeability after hydroxypropyl methylcellulose (HPMC) supplementation in diet-induced obese mice. | 2013 | Details |
| A23482 | 23740679 | J Pediatr Endocrinol Metab | Evaluation of serum neopterin levels and its relationship with adipokines in pediatric obesity-related nonalcoholic fatty liver disease and healthy adolescents. | 2013 | Details |
| A23484 | 23739675 | Int J Mol Sci | In vitro and in vivo models of non-alcoholic fatty liver disease (NAFLD). | 2013 | Details |
| A23490 | 23734760 | Metab Syndr Relat Disord | Genetic variation in the patatin-like phospholipase domain-containing protein-3 (PNPLA-3) gene in Asian Indians with nonalcoholic fatty liver disease. | 2013 | Details |
| A23496 | 23727264 | Gastroenterology | Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease. | 2013 | Details |
| A23500 | 23721173 | J Transl Med | Molecular signature of adipose tissue in patients with both non-alcoholic fatty liver disease (NAFLD) and polycystic ovarian syndrome (PCOS). | 2013 | Details |
| A23504 | 26201791 | Hepatol Int | Insulin resistance, inflammation, and nonalcoholic fatty liver disease in non-obese adults without metabolic syndrome components. | 2012 | Details |
| A23505 | 26201789 | Hepatol Int | Impact of combined therapy with alpha-lipoic and ursodeoxycolic acid on nonalcoholic fatty liver disease: double-blind, randomized clinical trial of efficacy and safety. | 2012 | Details |
| A23508 | 26201775 | Hepatol Int | Should visceral fat, strictly linked to hepatic steatosis, be depleted to improve survival? | 2012 | Details |
| A23511 | 25755484 | J Clin Exp Hepatol | The future liver of the Asia pacific: fatter and firmer from more fructose and fortune? | 2012 | Details |
| A23514 | 23718963 | J Mol Endocrinol | Molecular pathways involved in the improvement of non-alcoholic fatty liver disease. | 2013 | Details |
| A23516 | 23717739 | World J Hepatol | Nonalcoholic steatohepatitis in nonalcoholic fatty liver disease patients of Bangladesh. | 2013 | Details |
| A23519 | 23715726 | Am J Physiol Endocrinol Metab | Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet. | 2013 | Details |
| A23522 | 23711137 | Am J Chin Med | Triterpenoid-rich fraction from Ilex hainanensis Merr. attenuates non-alcoholic fatty liver disease induced by high fat diet in rats. | 2013 | Details |
| A23529 | 23703888 | Am J Epidemiol | Prevalence of nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition Examination Survey, 1988-1994. | 2013 | Details |
| A23530 | 23703776 | Hepatology | Importance of cardiometabolic risk factors in the association between nonalcoholic fatty liver disease and arterial stiffness in adolescents. | 2013 | Details |
| A23535 | 23702383 | Metabolism | Artemisia scoparia extract attenuates non-alcoholic fatty liver disease in diet-induced obesity mice by enhancing hepatic insulin and AMPK signaling independently of FGF21 pathway. | 2013 | Details |
| A23536 | 23702094 | BMC Pediatr | Omega-3 fatty acids for treatment of non-alcoholic fatty liver disease: design and rationale of randomized controlled trial. | 2013 | Details |
| A23539 | 23700488 | PLoS One | Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH. | 2013 | Details |
| A23542 | 23696823 | PLoS One | Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis. | 2013 | Details |
| A23544 | 23695216 | Am J Physiol Endocrinol Metab | Interferon regulatory factor 7 deficiency prevents diet-induced obesity and insulin resistance. | 2013 | Details |
| A23546 | 23692373 | Diabet Med | Late effects of childhood cancer treatment: severe hypertriglyceridaemia, central obesity, non alcoholic fatty liver disease and diabetes as complications of childhood total body irradiation. | 2013 | Details |
| A23549 | 23691267 | Oxid Med Cell Longev | Increased nitroxidative stress promotes mitochondrial dysfunction in alcoholic and nonalcoholic fatty liver disease. | 2013 | Details |
| A23551 | 23690766 | Int J Endocrinol | Independent Association between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: A Systematic Review and Meta-Analysis. | 2013 | Details |
| A23552 | 23688357 | Cardiovasc Diabetol | Association between non-alcoholic fatty pancreatic disease (NAFPD) and the metabolic syndrome: case-control retrospective study. | 2013 | Details |
| A23553 | 23688034 | BMC Med Genet | Risk interaction of obesity, insulin resistance and hormone-sensitive lipase promoter polymorphisms (LIPE-60 C > G) in the development of fatty liver. | 2013 | Details |
| A23558 | 23678860 | J Dig Dis | Prevalence and predictors of alanine aminotransferase elevation among normal weight, overweight and obese youth in Mexico. | 2013 | Details |
| A23559 | 23676586 | Intern Med | Effects of liraglutide, a human glucagon-like peptide-1 analogue, on body weight, body fat area and body fat-related markers in patients with type 2 diabetes mellitus. | 2013 | Details |
| A23563 | 23671723 | World J Hepatol | CD14 upregulation as a distinct feature of non-alcoholic fatty liver disease after pancreatoduodenectomy. | 2013 | Details |
| A23565 | 23671610 | PLoS One | The association between nonalcoholic fatty pancreas disease and diabetes. | 2013 | Details |
| A23567 | 23668723 | Proc Nutr Soc | Ectopic fat, insulin resistance and non-alcoholic fatty liver disease. | 2013 | Details |
| A23569 | 23666091 | Nutrients | Non-alcoholic fatty liver disease (NAFLD) and its connection with insulin resistance, dyslipidemia, atherosclerosis and coronary heart disease. | 2013 | Details |
| A23570 | 23665288 | J Hepatol | A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver. | 2013 | Details |
| A23574 | 23663767 | Zhonghua Gan Zang Bing Za Zhi | [Effects of quercetin on serum levels of resistin and IL-18 and on insulin resistance in nonalcoholic fatty liver disease rats]. | 2013 | Details |
| A23580 | 23659066 | Klin Med (Mosk) | [Low and very low density lipoproteins: pathogenetic and clinical significance]. | 2013 | Details |
| A23584 | 23656726 | Br J Nutr | Effects of long-term administration of saturated and n-3 fatty acid-rich diets on lipid utilisation and oxidative stress in rat liver and muscle tissues. | 2013 | Details |
| A23586 | 23656177 | Liver Int | Non-alcoholic fatty liver disease independently predicts prediabetes during a 7-year prospective follow-up. | 2013 | Details |
| A23588 | 23653642 | Int J Endocrinol | Nonalcoholic Fatty liver disease, diabetes mellitus and cardiovascular disease: newer data. | 2013 | Details |
| A23593 | 23651850 | Am J Physiol Endocrinol Metab | Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. | 2013 | Details |
| A23598 | 23643404 | Metabolism | Liver enzymes and vitamin D levels in metabolically healthy but obese individuals: Korean National Health and Nutrition Examination Survey. | 2013 | Details |
| A23599 | 23642511 | Am J Cardiol | Left ventricular function by echocardiography, tissue Doppler imaging, and carotid intima-media thickness in obese adolescents with nonalcoholic fatty liver disease. | 2013 | Details |
| A23604 | 23634670 | Diabetes Technol Ther | Obesity and diabetes: newer concepts in imaging. | 2013 | Details |
| A23606 | 23633195 | J Clin Endocrinol Metab | Association of glypican-4 with body fat distribution, insulin resistance, and nonalcoholic fatty liver disease. | 2013 | Details |
| A23607 | 23630437 | Int J Med Sci | Status of essential trace minerals and oxidative stress in viral hepatitis C patients with nonalcoholic fatty liver disease. | 2013 | Details |
| A23609 | 23627940 | Curr Med Chem | Pharmacological inhibition of protein tyrosine phosphatase 1B: a promising strategy for the treatment of obesity and type 2 diabetes mellitus. | 2013 | Details |
| A23613 | 23626730 | PLoS One | Influence of non-alcoholic fatty liver disease on autonomic changes evaluated by the time domain, frequency domain, and symbolic dynamics of heart rate variability. | 2013 | Details |
| A23614 | 23626003 | J Clin Endocrinol Metab | Circulating levels of FGF-21 in obese youth: associations with liver fat content and markers of liver damage. | 2013 | Details |
| A23616 | 23625197 | Curr Diab Rep | The future of thiazolidinedione therapy in the management of type 2 diabetes mellitus. | 2013 | Details |
| A23627 | 23618531 | J Nutr Biochem | Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice. | 2013 | Details |
| A23629 | 23616151 | J Clin Endocrinol Metab | Improved hepatic lipid composition following short-term exercise in nonalcoholic fatty liver disease. | 2013 | Details |
| A23630 | 23613622 | World J Gastroenterol | Dipeptidyl peptidase-4: a key player in chronic liver disease. | 2013 | Details |
| A23637 | 23607320 | Hepatol Res | Liver damage is not reversed during the lean period in diet-induced weight cycling in mice. | 2013 | Details |
| A23638 | 23607264 | Hepatol Res | Efficacy of probucol for the treatment of non-alcoholic steatohepatitis with dyslipidemia: An open-label pilot study. | 2013 | Details |
| A23640 | 23603008 | Food Chem Toxicol | Taraxacum official (dandelion) leaf extract alleviates high-fat diet-induced nonalcoholic fatty liver. | 2013 | Details |
| A23642 | 23602473 | Arch Med Res | Relationship between visceral adipose tissue and adiponectin, inflammatory markers and thyroid hormones in obese males with hepatosteatosis and insulin resistance. | 2013 | Details |
| A23643 | 23601769 | Clin Imaging | Importance of the liver ultrasound scores in pubertal obese children with nonalcoholic fatty liver disease. | 2012 | Details |
| A23644 | 23601740 | Med Clin (Barc) | [Risk factors associated with non-alcoholic fatty liver disease: a case-control study]. | 2013 | Details |
| A23645 | 23600632 | Metab Syndr Relat Disord | Relationship of serum fetuin-A levels with coronary atherosclerotic burden and NAFLD in patients undergoing elective coronary angiography. | 2013 | Details |
| A23647 | 23600144 | Yao Xue Xue Bao | [Effects of pomegranate flowers polyphenols on liver PON expression of diabetes combining non-alcoholic fat liver diseases rats]. | 2013 | Details |
| A23649 | 23597944 | Ann Endocrinol (Paris) | Relationship between hepatocellular carcinoma, metabolic syndrome and non-alcoholic fatty liver disease: which clinical arguments? | 2013 | Details |
| A23651 | 23597726 | Gastroenterology | Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. | 2013 | Details |
| A23656 | 23593497 | PLoS One | Neuroendocrine regulation and metabolism of glucose and lipids in primary chronic insomnia: a prospective case-control study. | 2013 | Details |
| A23665 | 23585904 | PLoS One | Fructus Xanthii attenuates hepatic steatosis in rats fed on high-fat diet. | 2013 | Details |
| A23666 | 23584921 | High Blood Press Cardiovasc Prev | Non-alcoholic fatty liver disease is not associated with vitamin D deficiency in essential hypertension. | 2013 | Details |
| A23667 | 23583988 | Intern Med | An increased circulating angiotensin II concentration is associated with hypoadiponectinemia and postprandial hyperglycemia in men with nonalcoholic fatty liver disease. | 2013 | Details |
| A23670 | 23578884 | J Hepatol | Sleep duration and quality in relation to non-alcoholic fatty liver disease in middle-aged workers and their spouses. | 2013 | Details |
| A23674 | 23576902 | ScientificWorldJournal | Current concepts and management approaches in nonalcoholic fatty liver disease. | 2013 | Details |
| A23677 | 23569998 | Asian Pac J Trop Biomed | Elevated alanine aminotransferase activity is not associated with dyslipidemias, but related to insulin resistance and higher disease grades in non-diabetic non-alcoholic fatty liver disease. | 2012 | Details |