Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A46227 | 20185740 | Diabetes Care | Effect of ezetimibe on hepatic fat, inflammatory markers, and apolipoprotein B-100 kinetics in insulin-resistant obese subjects on a weight loss diet. | 2010 | Details |
| A46230 | 20159747 | Orv Hetil | [Patomechanisms of hepatic steatosis]. | 2010 | Details |
| A46235 | 20137582 | Chin Med J (Engl) | Sleep apnea hypopnea syndrome and liver injury. | 2010 | Details |
| A46242 | 20080361 | Med Hypotheses | Adipocytokines in insulin resistance and non-alcoholic fatty liver disease: the two sides of the same coin. | 2010 | Details |
| A46244 | 20060143 | Metabolism | Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model. | 2010 | Details |
| A46246 | 20047129 | Swiss Med Wkly | Insulin resistance in chronic hepatitis C: mechanisms and clinical relevance. | 2009 | Details |
| A46248 | 20034933 | J Biol Chem | A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis. | 2009 | Details |
| A46257 | 19958653 | Zhonghua Gan Zang Bing Za Zhi | [Relationship between carotid atherosclerosis and nonalcoholic fatty liver disease]. | 2009 | Details |
| A46262 | 19945406 | Cell Metab | Prevention of steatosis by hepatic JNK1. | 2009 | Details |
| A46269 | 19913850 | Metabolism | The possible role of liver steatosis in defining metabolic syndrome in prepubertal children. | 2009 | Details |
| A46274 | 19849765 | Intern Med J | Non-alcoholic fatty liver disease and microalbuminuria in non-diabetic patients: role of insulin resistance. | 2009 | Details |
| A46276 | 19838201 | Nat Med | Foxo1 integrates insulin signaling with mitochondrial function in the liver. | 2009 | Details |
| A46278 | 19822488 | Hepatobiliary Pancreat Dis Int | Diabetes mellitus: a "true" independent risk factor for hepatocellular carcinoma? | 2009 | Details |
| A46283 | 19783528 | J Lipid Res | A subset of dysregulated metabolic and survival genes is associated with severity of hepatic steatosis in obese Zucker rats. | 2009 | Details |
| A46284 | 19772998 | J Pediatr | Pediatric nonalcoholic fatty liver disease in 2009. | 2009 | Details |
| A46304 | 19637289 | Hepatology | Aerobic exercise training reduces hepatic and visceral lipids in obese individuals without weight loss. | 2009 | Details |
| A46306 | 19616615 | Free Radic Biol Med | SREBP-1c in nonalcoholic fatty liver disease induced by Western-type high-fat diet plus fructose in rats. | 2009 | Details |
| A46310 | 19585655 | Hepatology | Adipokines in liver diseases. | 2009 | Details |
| A46312 | 19576817 | J Pediatr Adolesc Gynecol | The prevalence of abnormal liver enzymes and metabolic syndrome in obese adolescent females with polycystic ovary syndrome. | 2009 | Details |
| A46316 | 19561788 | Hippokratia | The multi-hit process and the antagonistic roles of tumor necrosis factor-alpha and adiponectin in non alcoholic fatty liver disease. | 2009 | Details |
| A46325 | 19541924 | Am J Physiol Gastrointest Liver Physiol | Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet. | 2009 | Details |
| A46328 | 19506316 | ILAR J | Metabolic consequences of sleep-disordered breathing. | 2009 | Details |
| A46332 | 19475679 | Hepatology | The gut-liver axis in nonalcoholic fatty liver disease: Another pathway to insulin resistance? | 2009 | Details |
| A46340 | 19444870 | Hepatology | Independent effects of physical activity in patients with nonalcoholic fatty liver disease. | 2009 | Details |
| A46343 | 19426389 | J Dig Dis | Bile acids and insulin resistance: implications for treating nonalcoholic fatty liver disease. | 2009 | Details |
| A46345 | 19403641 | Am J Clin Nutr | Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes. | 2009 | Details |
| A46354 | 19346774 | Nestle Nutr Workshop Ser Pediatr Program | Obesity, inflammation, and macrophages. | 2009 | Details |
| A46358 | 19333209 | Med Sci Monit | Dipeptidyl peptidase IV inhibitors: therapeutic potential in nonalcoholic fatty liver disease. | 2009 | Details |
| A46362 | 19307976 | Eur J Gastroenterol Hepatol | Overexpression of liver-specific cytochrome P4502E1 impairs hepatic insulin signaling in a transgenic mouse model of nonalcoholic fatty liver disease. | 2009 | Details |
| A46363 | 19303970 | Metabolism | Association between leptin and transaminases: 1-year follow-up study in 180 overweight children. | 2009 | Details |
| A46366 | 19284314 | Metab Syndr Relat Disord | Metabolic syndrome and cancer. | 2009 | Details |
| A46369 | 19262374 | Curr Opin Endocrinol Diabetes Obes | Nonalcoholic fatty liver disease in type 2 diabetes mellitus. | 2009 | Details |
| A46373 | 19232511 | Arch Biochem Biophys | Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion. | 2009 | Details |
| A46382 | 19155012 | Atherosclerosis | Iron, metabolic syndrome, nonalcoholic fatty liver disease and carotid atherosclerosis. | 2008 | Details |
| A46383 | 19145879 | Eksp Klin Gastroenterol | [Nonalcoholic fatty liver disease and insulin resistance: clinical, biochemical, and morphological parallels]. | 2008 | Details |
| A46386 | 19131468 | Diabetes Care | Synergy between adiposity, insulin resistance, metabolic risk factors, and inflammation in adolescents. | 2009 | Details |
| A46387 | 19120938 | Liver Int | Propensity for non-alcoholic fatty liver disease: more evidence for ethnic susceptibility. | 2009 | Details |
| A46389 | 19111006 | Hepatology | c-Jun N-terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease: Multiple roles in multiple steps. | 2009 | Details |
| A46390 | 19105205 | Hepatology | Ethnic differences in hepatic steatosis: an insulin resistance paradox? | 2009 | Details |
| A46393 | 19086170 | Scand J Gastroenterol | Reduced hepatic expression of adipose tissue triglyceride lipase and CGI-58 may contribute to the development of non-alcoholic fatty liver disease in patients with insulin resistance. | 2008 | Details |
| A46394 | 19072357 | Expert Rev Gastroenterol Hepatol | Impact of body weight, diet and lifestyle on nonalcoholic fatty liver disease. | 2008 | Details |
| A46395 | 19062531 | Genetika | [Adipokine genetics: unbalanced protein secretion by human adipose tissue as a cause of the metabolic syndrome]. | 2008 | Details |
| A46396 | 19053049 | Hepatology | Orlistat for overweight subjects with nonalcoholic steatohepatitis: A randomized, prospective trial. | 2009 | Details |
| A46407 | 19027012 | Gastroenterology | Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. | 2008 | Details |
| A46408 | 19000676 | Gastroenterology | The natural history of nonalcoholic fatty liver disease: insights from children and mice. | 2008 | Details |
| A46411 | 18972440 | Hepatology | Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. | 2008 | Details |
| A46412 | 18971485 | Endocr Rev | The metabolic syndrome. | 2008 | Details |
| A46415 | 18830789 | Obes Surg | Retinol and alpha-tocopherol in morbid obesity and nonalcoholic fatty liver disease. | 2008 | Details |
| A46416 | 18827582 | Curr Opin Clin Nutr Metab Care | Nonalcoholic fatty liver disease: the potential role of nutritional management. | 2008 | Details |
| A46418 | 20209757 | Rev Med Chir Soc Med Nat Iasi | [Adipocitokines and nonalcoholic steatohepatitis]. | 2010 | Details |
| A46420 | 18794597 | Eur J Gastroenterol Hepatol | Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease. | 2008 | Details |
| A46421 | 18792129 | Hepatology | Does the hormone of eternal youth protect against nonalcoholic steatohepatitis? | 2008 | Details |
| A46423 | 18787467 | Eur J Gastroenterol Hepatol | Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis. | 2008 | Details |
| A46425 | 18772330 | Am J Pathol | Prevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis. | 2008 | Details |
| A46432 | 18685459 | Curr Opin Clin Nutr Metab Care | Nutrition in pathophysiology and treatment of nonalcoholic fatty liver disease. | 2008 | Details |
| A46439 | 18666225 | Hepatology | Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis. | 2008 | Details |
| A46440 | 18664869 | J Pediatr Gastroenterol Nutr | Association of raised liver transaminases with physical inactivity, increased waist-hip ratio, and other metabolic morbidities in severely obese children. | 2008 | Details |
| A46442 | 18627005 | Hepatology | Peroxisome proliferator-activated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. | 2008 | Details |
| A46443 | 18626435 | Ann Hepatol | Clinical update on non-alcoholic fatty liver disease and steatohepatitis. | 2008 | Details |
| A46445 | 18611188 | Aliment Pharmacol Ther | Adipokines and cytokines in non-alcoholic fatty liver disease. | 2008 | Details |
| A46452 | 18542010 | Curr Opin Clin Nutr Metab Care | Role of dietary carbohydrates and macronutrients in the pathogenesis of nonalcoholic fatty liver disease. | 2008 | Details |
| A46456 | 18510615 | Am J Gastroenterol | In search of an ideal biomarker for nonalcoholic fatty liver disease. | 2008 | Details |
| A46460 | 18460922 | Curr Opin Lipidol | Hepatic triglyceride synthesis and nonalcoholic fatty liver disease. | 2008 | Details |
| A46461 | 18458848 | J Gastroenterol | High-sensitivity C-reactive protein and metabolic syndrome (insulin resistance syndrome), including nonalcoholic steatohepatitis. | 2008 | Details |
| A46470 | 18408460 | Curr Opin Gastroenterol | Recent advances in nonalcholic fatty liver disease. | 2008 | Details |
| A46480 | 18370731 | Metab Syndr Relat Disord | Non-alcoholic Fatty liver disease and malignancy as complications of insulin resistance. | 2005 | Details |
| A46482 | 18367000 | Curr Diab Rep | Fatty liver, insulin resistance, and dyslipidemia. | 2008 | Details |
| A46483 | 18366995 | Curr Diab Rep | Nonalcoholic fatty liver disease: diagnosis and relation to metabolic syndrome and approach to treatment. | 2008 | Details |
| A46486 | 18355813 | Gastroenterology | Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. | 2008 | Details |
| A46489 | 18344805 | Medicine (Baltimore) | Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity. | 2008 | Details |
| A46492 | 18277910 | J Clin Gastroenterol | Therapy for nonalcoholic fatty liver disease. | 2008 | Details |
| A46493 | 18277391 | Obesity (Silver Spring) | Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance. | 2008 | Details |
| A46495 | 18227502 | Diabetes Care | Metabolic complications of childhood obesity: identifying and mitigating the risk. | 2008 | Details |
| A46496 | 18268061 | Gut | Differential relationships between basal and post-load insulin resistance indices and hepatic fibrosis in chronic hepatitis C and in non-alcoholic fatty liver disease. | 2008 | Details |
| A46499 | 18245813 | Am J Pathol | Iron depletion by deferoxamine up-regulates glucose uptake and insulin signaling in hepatoma cells and in rat liver. | 2008 | Details |
| A46500 | 18235842 | Mol Med | Inflammatory mechanisms in the regulation of insulin resistance. | 2008 | Details |
| A46508 | 18187076 | Am J Med | Carotid artery intima-media thickness in nonalcoholic fatty liver disease. | 2008 | Details |
| A46510 | 30743783 | Expert Rev Endocrinol Metab | Inflammatory biomarkers associated with obesity and insulin resistance: a focus on lipocalin-2 and adipocyte fatty acid-binding protein. | 2008 | Details |
| A46512 | 18161723 | Hepatology | Nonalcoholic fatty liver disease (NAFLD) and cardiac lipotoxicity: Another piece of the puzzle. | 2008 | Details |
| A46514 | 18082476 | Dig Liver Dis | Relationship between nonalcoholic fatty liver disease prevalence and visceral fat in obese adolescents. | 2007 | Details |
| A46516 | 18068003 | Arch Med Res | Influence of insulin resistance and adipocytokines on elevated serum alanine aminotransferase in obese patients. | 2007 | Details |
| A46517 | 18054848 | Dig Liver Dis | Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease. | 2007 | Details |
| A46521 | 18008034 | J Gastroenterol | The impact of visceral fat in nonalcoholic fatty liver disease: cross-sectional and longitudinal studies. | 2007 | Details |
| A46522 | 17979073 | Semin Liver Dis | Endoplasmic reticulum stress and liver injury. | 2007 | Details |
| A46524 | 17965308 | Diabetes Care | Intrauterine growth retardation, insulin resistance, and nonalcoholic fatty liver disease in children: response to Nobili et al. | 2007 | Details |
| A46530 | 17904449 | Am J Med | Impact of diabetes on the severity of liver disease. | 2007 | Details |
| A46536 | 17720354 | Am J Med | Abdominal adiposity and cardiometabolic risk: do we have all the answers? | 2007 | Details |
| A46547 | 17691941 | Curr Med Chem | Hepatobiliary diseases and insulin resistance. | 2007 | Details |
| A46561 | 17578885 | Am J Physiol Endocrinol Metab | Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity. | 2007 | Details |
| A46568 | 17536073 | Diabetes Care | Intrauterine growth retardation, insulin resistance, and nonalcoholic fatty liver disease in children. | 2007 | Details |
| A46569 | 17526824 | Diabetes Care | Nonalcoholic fatty liver disease and insulin resistance in youth. | 2007 | Details |
| A46574 | 17512312 | Metabolism | Persistent elevation of liver function enzymes within the reference range is associated with increased cardiovascular risk in young adults: the Bogalusa Heart Study. | 2007 | Details |
| A46575 | 17498512 | Gastroenterology | Abnormal lipid and glucose metabolism in obesity: implications for nonalcoholic fatty liver disease. | 2007 | Details |
| A46576 | 17498510 | Gastroenterology | Obesity, inflammation, and insulin resistance. | 2007 | Details |
| A46594 | 17396083 | Gastroenterol Clin Biol | [Carbohydrate metabolism dysregulation in cirrhosis: pathophysiology, prognostic impact and therapeutic implications]. | 2007 | Details |
| A46603 | 17354303 | N Engl J Med | Pioglitazone in nonalcoholic steatohepatitis. | 2007 | Details |
| A46607 | 17324347 | Curr Infect Dis Rep | Mechanisms of glucose intolerance in patients with chronic hepatitis C: implications for treatment. | 2007 | Details |
| A46608 | 17318260 | J Clin Invest | Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. | 2007 | Details |
| A46609 | 17306008 | Acta Paediatr | MRI and ultrasound for hepatic fat quantification:relationships to clinical and metabolic characteristics of pediatric nonalcoholic fatty liver disease. | 2007 | Details |
| A46614 | 17278239 | World J Gastroenterol | Indian patients with nonalcoholic fatty liver disease presenting with raised transaminases are different at presentation. | 2007 | Details |