Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A51765 | 34279029 | J Clin Endocrinol Metab | Circulating Bile Acid Profiles: A Need for Further Examination. | 2021 | Details |
| A51769 | 34264866 | JCI Insight | Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. | 2021 | Details |
| A51771 | 34236076 | Clin Sci (Lond) | Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress. | 2021 | Details |
| A51773 | 34222458 | World J Clin Cases | Growth hormone cocktail improves hepatopulmonary syndrome secondary to hypopituitarism: A case report. | 2021 | Details |
| A51777 | 34143451 | FASEB J | Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice. | 2021 | Details |
| A51782 | 34116189 | J Ethnopharmacol | Danning tablets alleviate high fat diet-induced obesity and fatty liver in mice via modulating SREBP pathway. | 2021 | Details |
| A51784 | 34082137 | Mol Metab | Hemostatic alterations linked to body fat distribution, fatty liver, and insulin resistance. | 2021 | Details |
| A51785 | 34079069 | Int J Obes (Lond) | Effects of a novel polyphenol-rich plant extract on body composition, inflammation, insulin sensitivity, and glucose homeostasis in obese mice. | 2021 | Details |
| A51789 | 34064308 | Nutrients | Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats. | 2021 | Details |
| A51798 | 34019585 | PLoS One | FGF21 serum levels are related to insulin resistance, metabolic changes and obesity in Mexican people living with HIV (PLWH). | 2021 | Details |
| A51809 | 33957191 | Mol Cell Endocrinol | Retinol-binding protein 4 in obesity and metabolic dysfunctions. | 2021 | Details |
| A51813 | 33947390 | Cardiovasc Diabetol | Effects of pemafibrate on glucose metabolism markers and liver function tests in patients with hypertriglyceridemia: a pooled analysis of six phase 2 and phase 3 randomized double-blind placebo-controlled clinical trials. | 2021 | Details |
| A51814 | 33946738 | Cells | Hepatic Wnt1 Inducible Signaling Pathway Protein 1 (WISP-1/CCN4) Associates with Markers of Liver Fibrosis in Severe Obesity. | 2021 | Details |
| A51817 | 33941552 | BMJ Open Diabetes Res Care | Antidiabetic E4orf1 protein prevents hepatic steatosis and reduces markers of aging-related cellular damage in high fat fed older mice. | 2021 | Details |
| A51823 | 33923230 | Nutrients | High Choline Intake during Pregnancy Reduces Characteristics of the Metabolic Syndrome in Male Wistar Rat Offspring Fed a High Fat But Not a Normal Fat Post-Weaning Diet. | 2021 | Details |
| A51827 | 33894105 | Liver Int | Maternal nicotine exposure aggravates metabolic associated fatty liver disease via PI3K/Akt signaling in adult offspring mice. | 2021 | Details |
| A51834 | 33833481 | World J Gastroenterol | Metabolic complications of hepatitis C virus infection. | 2021 | Details |
| A51836 | 33812885 | Eur J Pharmacol | JNK signaling pathway in metabolic disorders: An emerging therapeutic target. | 2021 | Details |
| A51837 | 33809061 | Cells | Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge. | 2021 | Details |
| A51848 | 33746902 | Front Endocrinol (Lausanne) | The Impact of Gut Microbiome on Metabolic Disorders During Catch-Up Growth in Small-for-Gestational-Age. | 2021 | Details |
| A51859 | 33631318 | Cell Signal | Sphingosine 1-phosphate metabolism and insulin signaling. | 2021 | Details |
| A51866 | 33577395 | Metab Syndr Relat Disord | Usefulness of Triglyceride to High-Density Lipoprotein Ratio and Alanine Aminotransferase for Predicting Insulin Resistance and Metabolic Syndrome in the Japanese Population. | 2021 | Details |
| A51867 | 33575433 | Mol Ther Methods Clin Dev | Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice. | 2020 | Details |
| A51868 | 33568150 | Cancer Cell Int | The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers. | 2021 | Details |
| A51869 | 33556473 | Mol Cell Endocrinol | Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome. | 2021 | Details |
| A51872 | 33538983 | Obes Surg | Decrease of dipeptidyl peptidase 4 activity is associated with weight loss after bariatric surgery. | 2021 | Details |
| A51875 | 33514384 | Lipids Health Dis | The effects of canola and olive oils consumption compared to sunflower oil, on lipid profile and hepatic steatosis in women with polycystic ovarian syndrome: a randomized controlled trial. | 2021 | Details |
| A51878 | 33499061 | J Clin Med | Detection and Characterization of Phosphorylation, Glycosylation, and Fatty Acid Bound to Fetuin A in Human Blood. | 2021 | Details |
| A51883 | 33484562 | J Clin Endocrinol Metab | Adipose Insulin Resistance and Decreased Adiponectin Are Correlated With Metabolic Abnormalities in Nonobese Men. | 2021 | Details |
| A51886 | 33455774 | J Dairy Sci | Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. | 2021 | Details |
| A51887 | 33454435 | Biochim Biophys Acta Mol Cell Biol Lipids | Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats. | 2021 | Details |
| A51888 | 33449293 | Endocrine | Glucocorticoid signaling and lipid metabolism disturbances in the liver of rats treated with 5α-dihydrotestosterone in an animal model of polycystic ovary syndrome. | 2021 | Details |
| A51895 | 33384967 | Front Cell Infect Microbiol | Shifts in the Bacterial Community of Supragingival Plaque Associated With Metabolic-Associated Fatty Liver Disease. | 2020 | Details |
| A51897 | 33370494 | Am J Transplant | Uninephrectomy and class II PI3K-C2β inactivation synergistically protect against obesity, insulin resistance and liver steatosis in mice. | 2021 | Details |
| A51900 | 33356916 | Physiol Rev | Lipodistrophy: a paradigm for understanding the consequences of "overloading" adipose tissue. | 2020 | Details |
| A51901 | 33347566 | J Clin Endocrinol Metab | Plasma Bile Acids More Closely Align With Insulin Resistance, Visceral and Hepatic Adiposity Than Total Adiposity. | 2021 | Details |
| A51904 | 33323476 | Diabetes Care | Presence of Liver Steatosis Is Associated With Greater Diabetes Remission After Gastric Bypass Surgery. | 2020 | Details |
| A51905 | 33317050 | Int J Mol Sci | Adiponectin in Chronic Kidney Disease. | 2020 | Details |
| A51914 | 33273564 | Sci Rep | Short-term Cudrania tricuspidata fruit vinegar administration attenuates obesity in high-fat diet-fed mice by improving fat accumulation and metabolic parameters. | 2020 | Details |
| A51915 | 33273482 | Sci Rep | NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet. | 2020 | Details |
| A51916 | 33264641 | Cancer Lett | FGF21 in obesity and cancer: New insights. | 2020 | Details |
| A51917 | 33257902 | Int J Endocrinol Metab | Association of Maternal Dietary Components During Pregnancy and/or Lactation with Insulin-Dependent Diabetes Mellitus. | 2020 | Details |
| A51920 | 33233602 | Int J Mol Sci | Lipodystrophies-Disorders of the Fatty Tissue. | 2020 | Details |
| A51929 | 33144503 | Proc Natl Acad Sci U S A | Curtailing FGF19's mitogenicity by suppressing its receptor dimerization ability. | 2020 | Details |
| A51935 | 33083279 | Liver Cancer | Dietary Restriction Suppresses Steatosis-Associated Hepatic Tumorigenesis in Hepatitis C Virus Core Gene Transgenic Mice. | 2020 | Details |
| A51940 | 33049402 | Prostaglandins Other Lipid Mediat | Enalapril improves obesity associated liver injury ameliorating systemic metabolic markers by modulating Angiotensin Converting Enzymes ACE/ACE2 expression in high-fat feed mice. | 2020 | Details |
| A51943 | 33030294 | Obes Rev | Eating behaviour in contrasting adiposity phenotypes: Monogenic obesity and congenital generalized lipodystrophy. | 2020 | Details |
| A51946 | 33006467 | Minerva Endocrinol | Insulin resistance and hepatic steatosis in type 1 diabetes mellitus and their association with diabetic chronic complications. | 2020 | Details |
| A51957 | 32915147 | Turk J Gastroenterol | Magnetic resonance spectroscopy to assess hepatic steatosis in patients with lipodystrophy. | 2020 | Details |
| A51960 | 32879342 | Sci Rep | Impaired brain homeostasis and neurogenesis in diet-induced overweight zebrafish: a preventive role from A. borbonica extract. | 2020 | Details |
| A51968 | 32814419 | Endocrinol Metab (Seoul) | Metabolically Healthy and Unhealthy Normal Weight and Obesity. | 2020 | Details |
| A51982 | 32631703 | Nutr Metab Cardiovasc Dis | The increased amount of coffee consumption lowers the incidence of fatty liver disease in Korean men. | 2020 | Details |
| A51983 | 32628084 | Physiol Genomics | Hyperketonemia GWAS and parity-dependent SNP associations in Holstein dairy cows intensively sampled for blood β-hydroxybutyrate concentration. | 2020 | Details |
| A51984 | 32622204 | Theriogenology | Metabolic markers for purulent vaginal discharge and subclinical endometritis in dairy cows. | 2020 | Details |
| A51986 | 32611548 | Diabetes | A Small Molecule, UAB126, Reverses Diet-Induced Obesity and its Associated Metabolic Disorders. | 2020 | Details |
| A51991 | 32548470 | ACS Omega | Effects of Inulin Propionate Ester on Obesity-Related Metabolic Syndrome and Intestinal Microbial Homeostasis in Diet-Induced Obese Mice. | 2020 | Details |
| A51996 | 32512788 | Antioxidants (Basel) | Cold-Pressed Nigella Sativa Oil Standardized to 3% Thymoquinone Potentiates Omega-3 Protection against Obesity-Induced Oxidative Stress, Inflammation, and Markers of Insulin Resistance Accompanied with Conversion of White to Beige Fat in Mice. | 2020 | Details |
| A51999 | 32483543 | Pediatr Gastroenterol Hepatol Nutr | Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome. | 2020 | Details |
| A52005 | 32432943 | Autophagy | Discovery of a potent SCAP degrader that ameliorates HFD-induced obesity, hyperlipidemia and insulin resistance via an autophagy-independent lysosomal pathway. | 2020 | Details |
| A52007 | 32408016 | Mol Metab | Suppressing adipocyte inflammation promotes insulin resistance in mice. | 2020 | Details |
| A52009 | 32359213 | Mol Nutr Food Res | Novel Strategies to Prevent Total Parenteral Nutrition-Induced Gut and Liver Inflammation, and Adverse Metabolic Outcomes. | 2020 | Details |
| A52013 | 32294657 | Ann Nutr Metab | The rs11187533 C>T Variant of the FFAR4 Gene Is Associated with Lower Levels of Fasting Glucose and Decreases in Markers of Liver Injury in Children with Obesity. | 2020 | Details |
| A52015 | 32290082 | Int J Mol Sci | Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities. | 2020 | Details |
| A52017 | 32282852 | PLoS One | Early prevention of diabetes microvascular complications in people with hyperglycaemia in Europe. ePREDICE randomized trial. Study protocol, recruitment and selected baseline data. | 2020 | Details |
| A52018 | 32245824 | BMJ Open Diabetes Res Care | Relationship of obesity to adipose tissue insulin resistance. | 2020 | Details |
| A52020 | 32229290 | Clin Immunol | Comorbidities associated with psoriatic arthritis: Review and update. | 2020 | Details |
| A52022 | 32218769 | Front Endocrinol (Lausanne) | A Novel Indoline Derivative Ameliorates Diabesity-Induced Chronic Kidney Disease by Reducing Metabolic Abnormalities. | 2020 | Details |
| A52024 | 32198195 | Diabetes | Exercise Combats Hepatic Steatosis: Potential Mechanisms and Clinical Implications. | 2020 | Details |
| A52025 | 32193201 | BMJ Open Diabetes Res Care | Incidence of type 2 diabetes in familial combined hyperlipidemia. | 2020 | Details |
| A52028 | 32168920 | Int J Environ Res Public Health | Prevalence and Risk Factors of Metabolic Associated Fatty Liver Disease in Xinxiang, China. | 2020 | Details |
| A52029 | 32151973 | iScience | FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism. | 2020 | Details |
| A52030 | 32128655 | Rev Endocr Metab Disord | Type 2 diabetes - unmet need, unresolved pathogenesis, mTORC1-centric paradigm. | 2020 | Details |
| A52032 | 32120465 | Ceylon Med J | Association of Serum Uric acid and Gamma-glutamyltransferase with Obesity Related Metabolic Derangements in a Cohort of Children with Obesity in Sri Lanka | 2019 | Details |
| A52033 | 32110817 | Horm Metab Res | Association of Apolipoprotein C3 Levels and Hepatic Steatosis: A Follow-Up Study. | 2020 | Details |
| A52034 | 32079675 | J Biol Chem | Hepatic HAX-1 inactivation prevents metabolic diseases by enhancing mitochondrial activity and bile salt export. | 2020 | Details |
| A52035 | 32069304 | PLoS One | Irisin and markers of metabolic derangement in non-diabetic Caucasian subjects with stage I-II obesity during early aging. | 2020 | Details |
| A52040 | 31988048 | Biochim Biophys Acta Mol Cell Biol Lipids | Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice. | 2020 | Details |
| A52041 | 31984308 | Nat Metab | Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity. | 2019 | Details |
| A52042 | 31972148 | Clin Biochem | Circulating PCSK9 is associated with liver biomarkers and hepatic steatosis. | 2020 | Details |
| A52043 | 31944172 | Autophagy | Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells. | 2020 | Details |
| A52044 | 31935236 | PLoS One | OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model. | 2020 | Details |
| A52046 | 31924743 | Proc Natl Acad Sci U S A | Metabolic dysregulation in the Atp7b -/- Wilson's disease mouse model. | 2020 | Details |
| A52051 | 31888144 | Int J Mol Sci | Altered Metabolic Profile and Adipocyte Insulin Resistance Mark Severe Liver Fibrosis in Patients with Chronic Liver Disease. | 2019 | Details |
| A52052 | 31888081 | Nutrients | Yarrow Supercritical Extract Ameliorates the Metabolic Stress in a Model of Obesity Induced by High-Fat Diet. | 2019 | Details |
| A52056 | 31822562 | J Biol Chem | Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in nonobese diabetic mice. | 2019 | Details |
| A52060 | 31752080 | Nutrients | Genetic Deletion of Syndecan-4 Alters Body Composition, Metabolic Phenotypes, and the Function of Metabolic Tissues in Female Mice Fed A High-Fat Diet. | 2019 | Details |
| A52061 | 31746186 | Environ Sci Technol | Exposure to Persistent Organic Pollutants (POPs) and Their Relationship to Hepatic Fat and Insulin Insensitivity among Asian Indian Immigrants in the United States. | 2019 | Details |
| A52064 | 31706843 | Biochem Pharmacol | Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity. | 2019 | Details |
| A52065 | 31698809 | J Clin Med | Insulin Resistance Associated Disorders Pivoting Long-Term Hepatitis B Surface Antigen Decline During Entecavir Therapy. | 2019 | Details |
| A52069 | 31676981 | Diabetologia | Circulating palmitoleic acid is an independent determinant of insulin sensitivity, beta cell function and glucose tolerance in non-diabetic individuals: a longitudinal analysis. | 2019 | Details |
| A52075 | 31656583 | F1000Res | Recent advances in understanding lipodystrophy: a focus on lipodystrophy-associated cardiovascular disease and potential effects of leptin therapy on cardiovascular function. | 2019 | Details |
| A52078 | 31592400 | Diabetol Int | Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity. | 2019 | Details |
| A52079 | 31577934 | Cell Metab | Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins. | 2019 | Details |
| A52080 | 31573846 | Am J Physiol Endocrinol Metab | The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation. | 2019 | Details |
| A52081 | 31565213 | Ther Adv Endocrinol Metab | Update on the synergistic effect of HSL and insulin in the treatment of metabolic disorders. | 2019 | Details |
| A52082 | 31559327 | GE Port J Gastroenterol | Fatty Liver and Autoimmune Hepatitis: Two Forms of Liver Involvement in Lipodystrophies. | 2019 | Details |
| A52083 | 31557503 | Biochimie | Protocatechuic acid exhibits hepatoprotective, vasculoprotective, antioxidant and insulin-like effects in dexamethasone-induced insulin-resistant rats. | 2019 | Details |
| A52087 | 31467335 | Sci Rep | Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig. | 2019 | Details |
| A52088 | 31464373 | Mol Syst Biol | High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network. | 2019 | Details |
| A52091 | 31357412 | Int J Mol Sci | Adipogenesis: A Necessary but Harmful Strategy. | 2019 | Details |