Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52761 | 22350143 | J Nat Med | Puerariae flos alleviates metabolic diseases in Western diet-loaded, spontaneously obese type 2 diabetic model mice. | 2012 | Details |
| A52764 | 22318315 | Obesity (Silver Spring) | Adropin deficiency is associated with increased adiposity and insulin resistance. | 2012 | Details |
| A52768 | 22276255 | Indian J Endocrinol Metab | Metabolic syndrome in the Mediterranean region: Current status. | 2012 | Details |
| A52774 | 22185842 | Am J Physiol Endocrinol Metab | Generation and characterization of a mouse model of the metabolic syndrome: apolipoprotein E and aromatase double knockout mice. | 2011 | Details |
| A52776 | 22158268 | Int J Obes (Lond) | Impact of BMI on the incidence of metabolic abnormalities in metabolically healthy men. | 2011 | Details |
| A52778 | 22074439 | Curr Pharm Des | Evaluation of the possible contribution of antioxidants administration in metabolic syndrome. | 2011 | Details |
| A52782 | 22014839 | J Am Soc Echocardiogr | Epicardial adipose tissue relating to anthropometrics, metabolic derangements and fatty liver disease independently contributes to serum high-sensitivity C-reactive protein beyond body fat composition: a study validated with computed tomography. | 2011 | Details |
| A52783 | 22005032 | Biochim Biophys Acta | Hypertriglyceridemia secondary to obesity and diabetes. | 2011 | Details |
| A52784 | 21979150 | Biochim Biophys Acta | Fatty acid transport proteins, implications in physiology and disease. | 2011 | Details |
| A52786 | 21934202 | Indian J Pathol Microbiol | Steatosis in chronic hepatitis B: prevalence and correlation with biochemical, histologic, viral, and metabolic parameters. | 2012 | Details |
| A52787 | 21932846 | J Agric Food Chem | Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice. | 2011 | Details |
| A52788 | 21923735 | Diabetes Obes Metab | The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects. | 2011 | Details |
| A52790 | 21900826 | Eur J Gastroenterol Hepatol | Sex and race differences in the prevalence of fatty liver disease as measured by computed tomography liver attenuation in European American and African American participants of the NHLBI family heart study. | 2012 | Details |
| A52791 | 21892913 | Clin Chem Lab Med | New insights into adipose tissue dysfunction in insulin resistance. | 2011 | Details |
| A52793 | 21852815 | Obesity (Silver Spring) | Intestinal permeability is associated with visceral adiposity in healthy women. | 2011 | Details |
| A52794 | 21849896 | Curr Opin Clin Nutr Metab Care | Origins of metabolic complications in obesity: adipose tissue and free fatty acid trafficking. | 2011 | Details |
| A52796 | 21817098 | Arterioscler Thromb Vasc Biol | CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. | 2011 | Details |
| A52798 | 21756316 | Cardiovasc Diabetol | Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs. | 2011 | Details |
| A52800 | 21725989 | Hepatology | Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice. | 2011 | Details |
| A52801 | 21723507 | Cell Metab | Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome. | 2011 | Details |
| A52802 | 21613559 | Am J Clin Nutr | Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. | 2011 | Details |
| A52804 | 21549160 | Regul Pept | GLP-1-derived nonapeptide GLP-1(28-36)amide inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A52805 | 21536228 | Gend Med | Relations of adiponectin to levels of metabolic parameters and sexual hormones in elderly type 2 diabetic patients. | 2011 | Details |
| A52808 | 21490364 | Am J Physiol Regul Integr Comp Physiol | Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity. | 2011 | Details |
| A52809 | 21488080 | Hepatology | Fatty liver index and mortality: the Cremona study in the 15th year of follow-up. | 2011 | Details |
| A52810 | 21473944 | N Biotechnol | Antibodies in metabolic diseases. | 2011 | Details |
| A52812 | 21453770 | Biochim Biophys Acta | Cross-regulation of hepatic glucose metabolism via ChREBP and nuclear receptors. | 2011 | Details |
| A52813 | 21429276 | Br J Nutr | Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. | 2011 | Details |
| A52814 | 21406612 | Am J Physiol Endocrinol Metab | Dietary manipulation reveals an unexpected inverse relationship between fat mass and adipose 11β-hydroxysteroid dehydrogenase type 1. | 2011 | Details |
| A52815 | 21386801 | Int J Obes (Lond) | Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. | 2011 | Details |
| A52816 | 21382161 | Liver Int | Hepatic steatosis and insulin resistance are associated with severe fibrosis in patients with chronic hepatitis caused by HBV or HCV infection. | 2011 | Details |
| A52820 | 21318871 | Methods Mol Biol | Transgenic rodents with altered SSAT expression as models of pancreatitis and altered glucose and lipid metabolism. | 2011 | Details |
| A52821 | 21310864 | J Nutr | Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. | 2011 | Details |
| A52823 | 21270262 | Diabetes | Hypoxia-induced intrauterine growth restriction increases the susceptibility of rats to high-fat diet-induced metabolic syndrome. | 2011 | Details |
| A52824 | 21258310 | Med Glas (Zenica) | Increased P wave dispersion in patients with liver steatosis. | 2010 | Details |
| A52826 | 21250778 | Arch Physiol Biochem | Soluble CD36- a marker of the (pathophysiological) role of CD36 in the metabolic syndrome? | 2011 | Details |
| A52827 | 21199519 | J Gastroenterol Hepatol | Hepatic steatosis and hepatitis C: Still unhappy bedfellows? | 2011 | Details |
| A52828 | 21194577 | Am J Med | Initial combination therapy for type 2 diabetes mellitus: is it ready for prime time? | 2011 | Details |
| A52829 | 21205225 | Basic Clin Pharmacol Toxicol | Monosodium glutamate neonatal intoxication associated with obesity in adult stage is characterized by chronic inflammation and increased mRNA expression of peroxisome proliferator-activated receptors in mice. | 2011 | Details |
| A52831 | 21178610 | Curr Opin Clin Nutr Metab Care | Fatty acid regulation of hepatic lipid metabolism. | 2011 | Details |
| A52832 | 21151924 | PLoS One | Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice. | 2010 | Details |
| A52833 | 21145849 | J Hepatol | Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. | 2010 | Details |
| A52834 | 21112030 | Best Pract Res Clin Endocrinol Metab | Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. | 2010 | Details |
| A52839 | 21060311 | Int J Obes (Lond) | Perinatal nutrient restriction induces long-lasting alterations in the circadian expression pattern of genes regulating food intake and energy metabolism. | 2010 | Details |
| A52840 | 21036943 | Hum Mol Genet | Npc1 haploinsufficiency promotes weight gain and metabolic features associated with insulin resistance. | 2010 | Details |
| A52841 | 20980637 | J Nutr | Chronic parenteral nutrition induces hepatic inflammation, steatosis, and insulin resistance in neonatal pigs. | 2010 | Details |
| A52842 | 20965707 | Exp Toxicol Pathol | Diet modification and its influence on metabolic and related pathological alterations in the SHR/NDmcr-cp rat, an animal model of the metabolic syndrome. | 2010 | Details |
| A52843 | 20961644 | J Hepatol | Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease. | 2010 | Details |
| A52844 | 20876715 | Diabetes | Iron overload and diabetes risk: a shift from glucose to Fatty Acid oxidation and increased hepatic glucose production in a mouse model of hereditary hemochromatosis. | 2010 | Details |
| A52845 | 20835701 | Diabetologia | Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. | 2010 | Details |
| A52846 | 20832799 | Atherosclerosis | High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits. | 2010 | Details |
| A52847 | 20824098 | PLoS One | Myeloid differentiation factor 88 (MyD88)-deficiency increases risk of diabetes in mice. | 2010 | Details |
| A52848 | 20725711 | J Mol Med (Berl) | Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. | 2010 | Details |
| A52850 | 20699090 | Clin Chim Acta | Triglycerides and gallstone formation. | 2010 | Details |
| A52851 | 20685656 | J Biol Chem | SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells. | 2010 | Details |
| A52853 | 20670429 | Lipids Health Dis | Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. | 2010 | Details |
| A52854 | 20649581 | Br J Pharmacol | Irbesartan treatment up-regulates hepatic expression of PPARalpha and its target genes in obese Koletsky (fa(k)/fa(k)) rats: a link to amelioration of hypertriglyceridaemia. | 2010 | Details |
| A52855 | 20625970 | Horm Metab Res | Combination therapy with nateglinide and vildagliptin improves postprandial metabolic derangements in Zucker fatty rats. | 2010 | Details |
| A52857 | 20592272 | Endocr Rev | Gut microbiota, lipopolysaccharides, and innate immunity in the pathogenesis of obesity and cardiovascular risk. | 2010 | Details |
| A52862 | 20536513 | Diabet Med | Do high ferritin levels confer lower cardiovascular risk in men with Type 2 diabetes? | 2010 | Details |
| A52865 | 20495737 | Rom J Morphol Embryol | Hepatocyte steatosis in patients infected with genotype 1 hepatitis C virus. | 2010 | Details |
| A52867 | 20480550 | Curr Opin Lipidol | Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein. | 2010 | Details |
| A52871 | 20392876 | Mol Endocrinol | Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease. | 2010 | Details |
| A52873 | 20376319 | PLoS One | The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity. | 2010 | Details |
| A52874 | 20361178 | Diabetologia | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. | 2010 | Details |
| A52875 | 20340066 | Horm Metab Res | Leptin treatment during lactation programs leptin synthesis, intermediate metabolism, and liver microsteatosis in adult rats. | 2010 | Details |
| A52876 | 20336705 | Hepatology | Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. | 2010 | Details |
| A52882 | 20110573 | Arterioscler Thromb Vasc Biol | Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice. | 2010 | Details |
| A52886 | 20021538 | J Clin Hypertens (Greenwich) | Pathogenesis and pathophysiology of the cardiometabolic syndrome. | 2009 | Details |
| A52891 | 19920214 | Am J Physiol Endocrinol Metab | Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERalpha-deficient mice. | 2009 | Details |
| A52892 | 19875992 | Obesity (Silver Spring) | The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. | 2009 | Details |
| A52893 | 19859993 | World J Gastroenterol | Steatosis and insulin resistance in hepatitis C: a way out for the virus? | 2009 | Details |
| A52896 | 19850541 | An Pediatr (Barc) | [Fatty liver disease, insulin resistance and adiponectin in an obese pediatric population]. | 2009 | Details |
| A52897 | 19844213 | Int J Obes (Lond) | Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent. | 2009 | Details |
| A52898 | 19822001 | Lipids Health Dis | A high oleic sunflower oil fatty acid esters of plant sterols mixed with dietary diacylglycerol reduces plasma insulin and body fat accumulation in Psammomys obesus. | 2009 | Details |
| A52899 | 19809411 | Am J Gastroenterol | Interaction of adipokines and hepatitis B virus on histological liver injury in the Chinese. | 2009 | Details |
| A52901 | 19796990 | Curr Opin Pharmacol | The role of mitochondria in health and disease. | 2009 | Details |
| A52902 | 19796707 | Biochim Biophys Acta | Hypothalamic lipotoxicity and the metabolic syndrome. | 2009 | Details |
| A52903 | 19796705 | Biochim Biophys Acta | Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome. | 2009 | Details |
| A52904 | 19773738 | Int J Obes (Lond) | Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. | 2009 | Details |
| A52907 | 19729476 | Am J Pathol | Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells. | 2009 | Details |
| A52908 | 19706383 | Proc Natl Acad Sci U S A | Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. | 2009 | Details |
| A52909 | 19690766 | Rom J Morphol Embryol | Role of oxidative stress in the pathogenesis of chronic hepatitis C (CHC). | 2009 | Details |
| A52912 | 19632092 | Nutrition | Bile duct obstruction is associated with early postoperative upregulation of liver uncoupling protein-2 and reduced circulating glucose concentration in the rat. | 2009 | Details |
| A52913 | 19631025 | Br J Nutr | Experimental rat models to study the metabolic syndrome. | 2009 | Details |
| A52914 | 19623253 | PLoS One | Humanin: a novel central regulator of peripheral insulin action. | 2009 | Details |
| A52915 | 19584878 | Obesity (Silver Spring) | Metabolic implications of dietary trans-fatty acids. | 2009 | Details |
| A52916 | 19564844 | Lab Invest | Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice. | 2009 | Details |
| A52921 | 19509184 | Am J Physiol Endocrinol Metab | Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. | 2009 | Details |
| A52922 | 19501581 | Clin Biochem | Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. | 2009 | Details |
| A52923 | 19500808 | Metabolism | A herbal extract with acetyl-coenzyme A carboxylase inhibitory activity and its potential for treating metabolic syndrome. | 2009 | Details |
| A52927 | 19421860 | Apoptosis | Diabetes and apoptosis: lipotoxicity. | 2009 | Details |
| A52932 | 19358089 | Exp Clin Endocrinol Diabetes | Adipose tissue dysfunction in obesity. | 2009 | Details |
| A52933 | 19357846 | Semin Immunopathol | The emerging role of the endocannabinoid system in cardiovascular disease. | 2009 | Details |
| A52934 | 19349323 | Circulation | Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus. | 2009 | Details |
| A52935 | 19318113 | Pharmacol Ther | Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease. | 2009 | Details |
| A52936 | 19292832 | Aliment Pharmacol Ther | Influence of insulin resistance on hepatic fibrosis and steatosis in hepatitis C virus (HCV) mono-infected compared with HIV-HCV co-infected patients. | 2009 | Details |
| A52937 | 19277603 | Diabetologia | Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy. | 2009 | Details |
| A52940 | 19259639 | J Mol Med (Berl) | Elovl6: a new player in fatty acid metabolism and insulin sensitivity. | 2009 | Details |
| A52941 | 19148799 | J Gastroenterol | Steatosis, liver injury, and hepatocarcinogenesis in hepatitis C viral infection. | 2009 | Details |