Bioactive Compound Details
| Compound ID: | B145016 |
| Source ID: | CHEMBL64894 |
| Source Type: | Small molecule |
| Compound Name: | GENTIAN VIOLET |
| Synonyms: | BASIC VIOLET 1|BASIC VIOLET 3|C.I. 42535|C.I. BASIC VIOLET 1|C.I. BASIC VIOLET 3|CI 42535|CRYSTAL VIOLET|GENAPAX|GENTIAN VIOLET|GNF-Pf-880|GV 11|LOWACRYL VIOLET 1|METHYL VIOLET|METHYL VIOLET 10B|METHYLROSANILINE CHLORIDE|METHYLROSANILINII CHLORIDUM|METHYLROSANILINIUM CHLORIDE|Methylrosaniline Cl|Methylrosanilinium Cl|NSC-3090|Pyoktanin|Viocid |
| Molecular Formula: | C25H30ClN3 |
| SMILES: | CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1.[Cl-] |
| Molecular Species: | NEUTRAL |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T07 | Bile acid receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T17 | Farnesoid X-activated receptor | NR1H4 | agonist | Nuclear hormone receptor | Q96RI1 | NR1H4_HUMAN | Details |
| T04 | Peroxisome proliferator-activated receptor delta | PPARD | agonist | Nuclear hormone receptor | Q03181 | PPARD_HUMAN | Details |
| T05 | Peroxisome proliferator-activated receptor gamma | PPARG | agonist | Nuclear hormone receptor | P37231 | PPARG_HUMAN | Details |
| T26 | Thyroid hormone receptor beta | THRB | agonist | Nuclear hormone receptor | P10828 | THB_HUMAN | Details |
| T08 | Tumor necrosis factor | TNF | inhibitor | Cytokine | P01375 | TNFA_HUMAN | Details |
| T45 | Arachidonate 12-lipoxygenase | ALOX12 | inhibitor | Enzyme | P18054 | LOX12_HUMAN | Details |