Bioactive Compound Details
| Compound ID: | B145833 |
| Source ID: | CHEMBL964 |
| Source Type: | Small molecule |
| Compound Name: | DISULFIRAM |
| Synonyms: | Antabuse|DISULFIRAM|Disulfiram|ESPERAL|NSC-25953|ORA-102|ORA102 |
| Molecular Formula: | C10H20N2S4 |
| SMILES: | CCN(CC)C(=S)SSC(=S)N(CC)CC |
| Molecular Species: | None |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T15 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | HMGCR | inhibitor | Enzyme | P04035 | HMDH_HUMAN | Details |
| T10 | Caspase-1 | CASP1 | inhibitor | Enzyme | P29466 | CASP1_HUMAN | Details |
| T24 | C-C chemokine receptor type 2 | CCR2 | antagonist | GPCR | P41597 | CCR2_HUMAN | Details |
| T25 | C-C chemokine receptor type 5 | CCR5 | antagonist | GPCR | P51681 | CCR5_HUMAN | Details |
| T30 | Lysyl oxidase homolog 2 | LOXL2 | antibody | Enzyme | Q9Y4K0 | LOXL2_HUMAN | Details |
| T23 | Type-1 angiotensin II receptor | AGTR1 | antagonist | GPCR | P30556 | AGTR1_HUMAN | Details |
| T45 | Arachidonate 12-lipoxygenase | ALOX12 | inhibitor | Enzyme | P18054 | LOX12_HUMAN | Details |