Therapeutic Targets
Therapeutic targets for NAFLD are manually extracted from research articles. For each target, reference researches are provided, and target details are derived from UniProt. Related drugs and repositioning candidates in NAFLDkb are presented with knowledge graphs.
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45 records.
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name | |
|---|---|---|---|---|---|---|---|
| T42 | Serine/threonine-protein kinase 17B | STK17B | inhibitor | Kinase | O94768 | ST17B_HUMAN | Details |
| T43 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | TAB1 | inhibitor | Kinase | Q15750 | TAB1_HUMAN | Details |
| T44 | Amine oxidase, copper containing | AOC3 | inhibitor | Enzyme | Q16853 | AOC3_HUMAN | Details |
| T45 | Arachidonate 12-lipoxygenase | ALOX12 | inhibitor | Enzyme | P18054 | LOX12_HUMAN | Details |
| T46 | ATP-citrate synthase | ACLY | inhibitor | Transferase | P53396 | ACLY_HUMAN | Details |