Therapeutic Targets

Therapeutic targets for NAFLD are manually extracted from research articles. For each target, reference researches are provided, and target details are derived from UniProt. Related drugs and repositioning candidates in NAFLDkb are presented with knowledge graphs.

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     fibrosis
8 records.
Target ID Target Name GENE Action Class UniProtKB ID Entry Name
T01 5'-AMP-activated protein kinase subunit beta-1 PRKAB1 activator Kinase Q9Y478 AAKB1_HUMAN Details
T07 Bile acid receptor NR1H4 agonist Nuclear hormone receptor Q96RI1 NR1H4_HUMAN Details
T09 Toll-like receptor 4 TLR4 antagonist Membrane receptor O00206 TLR4_HUMAN Details
T10 Caspase-1 CASP1 inhibitor Enzyme P29466 CASP1_HUMAN Details
T11 Caspase-3 CASP3 inhibitor Enzyme P42574 CASP3_HUMAN Details
T13 Apoptosis Signal-regulating Kinase 1 ASK1 inhibitor Enzyme Q99683 M3K5_HUMAN Details
T23 Type-1 angiotensin II receptor AGTR1 antagonist GPCR P30556 AGTR1_HUMAN Details
T38 Caspase-4 Casp4 inhibitor Enzyme P49662 CASP4_HUMAN Details