| Trial ID: | L0792 |
| Source ID: | IRCT20170430033730N2
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| Associated Drug: |
Silybum marianum
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| Title: |
The Combined Effect of Silybum marianum, Cynara scolymus, Curcuma longa and Taraxacum officinale extracts on metabolic parameters, oxidative stress biomarkers and inflammation in patients with Non-alcoholic fatty liver disease
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| Acronym: |
--
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| Status: |
Not Recruiting
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| Study Results: |
No Results Available
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| Results: |
--
|
| Conditions: |
Non-alcoholic fatty liver. <br>Fatty (change of) liver, not elsewhere classified
|
| Interventions: |
Intervention 1: Intervention group: Two capsules of 275 mg of combined extract were taken twice daily for twelve weeks. Intervention 2: Control group: Two capsules of 275 mg of placebo were taken twice a day for 12 weeks.
|
| Outcome Measures: |
FBS. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;Insulin. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: ELISA.TG. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;Cholesterol. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;HDL. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;LDL. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;AST. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;ALT. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;Glutathion. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;MDA. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: Spectrophotometry.;IL-1. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: ELISA.;TNF-a. Timepoint: At the beginning of the study and 12 weeks after the intervention. Method of measurement: ELISA.
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| Sponsor/Collaborators: |
Qazvin University of Medical Sciences
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| Gender: |
All
|
| Age: |
30 years70 years
|
| Phases: |
Not applicable
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| Enrollment: |
60
|
| Study Type: |
interventional
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| Study Designs: |
Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: Simple randomization, Blinding description: A placebo was used to blind. Researchers and Patients will be blinded by t
|
| Start Date: |
02/07/2018
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| Completion Date: |
--
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| Results First Posted: |
--
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| Last Update Posted: |
11 September 2018
|
| Locations: |
Iran (Islamic Republic of)
|
| URL: |
http://en.irct.ir/trial/32012
|
