Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A48114 | 22955269 | J Biol Chem | Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β. | 2012 | Details |
| A48129 | 22248781 | Pediatr Endocrinol Diabetes Metab | [Insulin resistance in children]. | 2011 | Details |
| A48143 | 21519236 | Curr Opin Clin Nutr Metab Care | Osteocalcin: a new link between bone and energy metabolism. Some evolutionary clues. | 2011 | Details |
| A48150 | 21239437 | Endocrinology | Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats. | 2011 | Details |
| A48157 | 21107605 | Eur J Pediatr | Obesity, metabolic syndrome, and insulin dynamics in children after craniopharyngioma surgery. | 2010 | Details |
| A48161 | 20953409 | Vet Med Int | Lycopene prevents development of steatohepatitis in experimental nonalcoholic steatohepatitis model induced by high-fat diet. | 2010 | Details |
| A48164 | 20861239 | Endocrinology | Caloric restriction reverses hepatic insulin resistance and steatosis in rats with low aerobic capacity. | 2010 | Details |
| A48181 | 20530928 | Nihon Shokakibyo Gakkai Zasshi | A case of systemic lupus erythematosus with liver damage. | 2010 | Details |
| A48191 | 20105583 | J Pediatr Surg | A prospective trial for laparoscopic adjustable gastric banding in morbidly obese adolescents: an interim report of weight loss, metabolic and quality of life outcomes. | 2010 | Details |
| A48212 | 19549744 | J Clin Endocrinol Metab | Thyroid hormone-related regulation of gene expression in human fatty liver. | 2009 | Details |
| A48219 | 19407661 | J Clin Gastroenterol | Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects. | 2010 | Details |
| A48223 | 19346786 | Korean J Hepatol | [The value of serum retinol-binding protein 4 levels for determining disease severity in patients with chronic liver disease]. | 2009 | Details |
| A48227 | 19183340 | Aliment Pharmacol Ther | Mechanism of action of metformin in nonalcoholic steatohepatitis. | 2009 | Details |
| A48252 | 18563498 | Obes Surg | Metabolic syndrome is related to nonalcoholic steatohepatitis in severely obese subjects. | 2008 | Details |
| A48254 | 18408454 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2008 | Details |
| A48257 | 18316359 | Diabetes | Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis. | 2008 | Details |
| A48270 | 17940115 | J Clin Endocrinol Metab | Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy. | 2007 | Details |
| A48273 | 17845546 | Liver Int | Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis. | 2007 | Details |
| A48277 | 17659597 | Hepatology | Metabolic correlates of nonalcoholic fatty liver in women and men. | 2007 | Details |
| A48281 | 17476199 | Med Sci Monit | Cirrhosis in Werner's syndrome: an unusual presentation of premature aging. | 2007 | Details |
| A48292 | 17241893 | Gastroenterology | Insulin resistance: cause or consequence of nonalcoholic steatohepatitis? | 2007 | Details |
| A48294 | 17135591 | N Engl J Med | Thiazolidinediones for nonalcoholic steatohepatitis--promising but not ready for prime time. | 2006 | Details |
| A48295 | 17135584 | N Engl J Med | A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. | 2006 | Details |
| A48298 | 17037330 | Nihon Naika Gakkai Zasshi | [Diagnosis of and therapy for nonalcoholic steatohepatitis]. | 2006 | Details |
| A48306 | 16998299 | Korean J Hepatol | [Nonalcoholic steatohepatitis]. | 2006 | Details |
| A48317 | 30290456 | Expert Rev Endocrinol Metab | Obesity, insulin resistance, Type 2 diabetes and free fatty acids. | 2006 | Details |
| A48319 | 16772767 | Am J Ther | Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk. | 2006 | Details |
| A48325 | 16522283 | Curr Diab Rep | Metabolic syndrome in the elderly. | 2006 | Details |
| A48330 | 16378280 | Turk J Gastroenterol | Obesity and related parameters of non-alcoholic steatohepatitis. | 2002 | Details |
| A48334 | 16256425 | Hepatol Res | Nonalcoholic steatohepatitis in Asia-Oceania. | 2005 | Details |
| A48338 | 16181372 | Am J Gastroenterol | Hepatic steatosis in Dunnigan-type familial partial lipodystrophy. | 2005 | Details |
| A48341 | 16128278 | Pol Arch Med Wewn | [Effect of high-fat diet, rosiglitazone on lipid profile, insulin resistance and liver steatosis development]. | 2005 | Details |
| A48345 | 15835633 | Ned Tijdschr Geneeskd | [Nonalcoholic steatohepatitis: diagnosis, pathogenesis, treatment and prognosis]. | 2005 | Details |
| A48351 | 15625648 | Clin Gastroenterol Hepatol | Treatment of nonalcoholic steatohepatitis: antioxidants or insulin sensitizers? | 2004 | Details |
| A48354 | 15570868 | Nihon Shokakibyo Gakkai Zasshi | [Treatment of nonalcoholic steatohepatitis (NASH)]. | 2004 | Details |
| A48361 | 15240593 | J Clin Endocrinol Metab | Proteinuric nephropathy in acquired and congenital generalized lipodystrophy: baseline characteristics and course during recombinant leptin therapy. | 2004 | Details |
| A48363 | 15199412 | J Clin Invest | Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. | 2004 | Details |
| A48376 | 14557475 | J Clin Endocrinol Metab | Body fat distribution and cortisol metabolism in healthy men: enhanced 5beta-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver. | 2003 | Details |
| A48383 | 12866461 | Nihon Naika Gakkai Zasshi | [Recent topics on nonalcoholic steatohepatitis]. | 2003 | Details |
| A48388 | 12768401 | J Gastroenterol | "Insufficient" leptin production for the fat mass: a risk factor for nonalcoholic steatohepatitis in obese patients? | 2003 | Details |
| A48392 | 12663460 | Diabetes | Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma. | 2003 | Details |
| A48400 | 12464976 | Can J Gastroenterol | Serum levels of triglyceride and insulin resistance in patients with nonalcoholic steatohepatitis. | 2002 | Details |
| A48403 | 12364344 | Hypertension | Obesity hypertension in children: a problem of epidemic proportions. | 2002 | Details |
| A48418 | 11866302 | Am J Gastroenterol | Hyperinsulinemia in nondiabetic, both obese and nonobese patients with nonalcoholic steatohepatitis. | 2002 | Details |
| A48423 | 11557505 | Am J Physiol Gastrointest Liver Physiol | Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription. | 2001 | Details |
| A48429 | 11232664 | Am J Gastroenterol | Insulin resistance and nonalcoholic steatohepatitis: fat or fiction? | 2001 | Details |
| A48437 | 10990076 | Diabetologia | Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with type II diabetes. | 2000 | Details |
| A48439 | 10945719 | Curr Opin Lipidol | Serum triglycerides, the liver and the pancreas. | 2000 | Details |
| A48467 | 9346736 | Liver Transpl Surg | Recurrence of nonalcoholic steatohepatitis after liver transplantation. | 1997 | Details |
| A48473 | 8581074 | Int J Obes Relat Metab Disord | Liver disturbances in obesity and diabetes mellitus. | 1995 | Details |
| A48481 | 8234924 | Recent Dev Alcohol | Recent developments in alcoholism:the liver. | 1993 | Details |
| A48482 | 2227807 | Hepatology | Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors. | 1990 | Details |
| A48526 | 34774873 | Life Sci | GPR40 agonist inhibits NLRP3 inflammasome activation via modulation of nuclear factor-κB and sarco/endoplasmic reticulum Ca2+-ATPase. | 2021 | Details |
| A48530 | 34647189 | Diabetes Ther | Are the Protean Effects of Pentoxifylline in the Therapy of Diabetes and Its Complications Still Relevant? | 2021 | Details |
| A48533 | 34616107 | J Clin Biochem Nutr | Spirulina platensis and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis model. | 2021 | Details |
| A48544 | 34364773 | Nutr Metab Cardiovasc Dis | Hepatic fibrosis of any origin in a large population of type 2 diabetes patients. | 2021 | Details |
| A48573 | 33815359 | Front Immunol | Adipocyte Fatty Acid-Binding Protein, Cardiovascular Diseases and Mortality. | 2021 | Details |
| A48582 | 33659253 | Front Cell Dev Biol | Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research. | 2021 | Details |
| A48597 | 33387847 | Cell Calcium | Role of mitochondria in liver metabolic health and diseases. | 2020 | Details |
| A48612 | 33113429 | Biomed Pharmacother | Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review. | 2020 | Details |
| A48631 | 32651404 | Sci Rep | Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects. | 2020 | Details |
| A48639 | 32592089 | J Physiol Biochem | Lactosylceramide induced by elastin-derived peptides decreases adipocyte differentiation. | 2020 | Details |
| A48656 | 32195457 | JHEP Rep | miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction. | 2020 | Details |
| A48672 | 31823815 | Hum Genomics | Investigating RNA expression profiles altered by nicotinamide mononucleotide therapy in a chronic model of alcoholic liver disease. | 2019 | Details |
| A48677 | 31680948 | Front Pharmacol | Characterization of the Therapeutic Profile of Albiflorin for the Metabolic Syndrome. | 2019 | Details |
| A48696 | 31368881 | Endocr Metab Immune Disord Drug Targets | Key Relevance of Epigenetic Programming of Adiponectin Gene in Pathogenesis of Metabolic Disorders. | 2020 | Details |
| A48704 | 31089967 | Obes Surg | Quantification of Liver, Subcutaneous, and Visceral Adipose Tissues by MRI Before and After Bariatric Surgery. | 2019 | Details |
| A48710 | 31000363 | J Hepatol | Clinical utility of genomic analysis in adults with idiopathic liver disease. | 2019 | Details |
| A48713 | 30917505 | Int J Mol Sci | Role of SIRT-3, p-mTOR and HIF-1α in Hepatocellular Carcinoma Patients Affected by Metabolic Dysfunctions and in Chronic Treatment with Metformin. | 2019 | Details |
| A48717 | 30817309 | Rev Neurosci | The effects of dietary methionine restriction on the function and metabolic reprogramming in the liver and brain - implications for longevity. | 2019 | Details |
| A48736 | 30305645 | Sci Rep | Hesperidin and capsaicin, but not the combination, prevent hepatic steatosis and other metabolic syndrome-related alterations in western diet-fed rats. | 2018 | Details |
| A48755 | 29611411 | Yonsei Med J | Erratum to "Pathologic Impact of Insulin Resistance and Sensitivity on the Severity of Liver Histopathology in Pediatric Non-Alcoholic Steatohepatitis" by Park BH, et al. (Yonsei Med J 2017;58:756-762.). | 2018 | Details |
| A48770 | 29293679 | PLoS One | Functional role of ADAMTS5 in adiposity and metabolic health. | 2018 | Details |
| A48789 | 28711599 | Biochim Biophys Acta Mol Basis Dis | Arachidonic acid sex-dependently affects obesity through linking gut microbiota-driven inflammation to hypothalamus-adipose-liver axis. | 2017 | Details |
| A48811 | 27775791 | Eur Rev Med Pharmacol Sci | Association between irisin and major chronic diseases: a review. | 2016 | Details |
| A48819 | 27639537 | Lancet Diabetes Endocrinol | Clinical relevance of the bile acid receptor TGR5 in metabolism. | 2016 | Details |
| A48821 | 27618008 | Int J Mol Sci | Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations. | 2016 | Details |
| A48826 | 27467521 | PLoS One | Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice. | 2016 | Details |
| A48836 | 27003699 | Obes Surg | The Effect of Roux-en-Y vs. Omega-Loop Gastric Bypass on Liver, Metabolic Parameters, and Weight Loss. | 2016 | Details |
| A48842 | 26797127 | J Biol Chem | Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21. | 2016 | Details |
| A48850 | 26680665 | Physiol Res | Fasting and nonfasting triglycerides in cardiovascular and other diseases. | 2015 | Details |
| A48910 | 24804175 | Liver Cancer | Hepatic iron overload and hepatocellular carcinoma. | 2014 | Details |
| A48932 | 24090942 | Best Pract Res Clin Gastroenterol | Liver abnormalities and endocrine diseases. | 2013 | Details |
| A48933 | 24068196 | Int J Mol Med | Metformin decreases high-fat diet-induced renal injury by regulating the expression of adipokines and the renal AMP-activated protein kinase/acetyl-CoA carboxylase pathway in mice. | 2013 | Details |
| A48934 | 24032513 | Mini Rev Med Chem | Triglyceride Metabolism and Hepatic Diseases. | 2013 | Details |
| A48942 | 23700549 | Adipocyte | Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice. | 2013 | Details |
| A48964 | 23027617 | Carcinogenesis | Preventive effects of branched-chain amino acid supplementation on the spontaneous development of hepatic preneoplastic lesions in C57BL/KsJ-db/db obese mice. | 2012 | Details |
| A48971 | 22801434 | Panminerva Med | Metabolic derangements mediate cognitive impairment and Alzheimer's disease: role of peripheral insulin-resistance diseases. | 2012 | Details |
| A48972 | 22721876 | Nutrition | Caffeine attenuates metabolic syndrome in diet-induced obese rats. | 2012 | Details |
| A48981 | 22412843 | PLoS One | Prolyl isomerase Pin1 regulates mouse embryonic fibroblast differentiation into adipose cells. | 2012 | Details |
| A48984 | 22337830 | J Alzheimers Dis | Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewed. | 2012 | Details |
| A48991 | 22182059 | Scand J Gastroenterol | Circulating vaspin and its relationship with insulin sensitivity, adiponectin and liver histology in subjects with non-alcoholic steatohepatitis. | 2011 | Details |
| A49000 | 21951092 | Dig Endosc | Non-alcoholic steatohepatitis mimicking liver metastasis in obesity surgery. | 2011 | Details |
| A49009 | 21466434 | Curr Pharm Biotechnol | Silymarin in the prevention and treatment of liver diseases and primary liver cancer. | 2012 | Details |
| A49013 | 21329534 | Ned Tijdschr Geneeskd | [Diabetes mellitus and cirrhosis of the liver: a prognostically unfavourable combination]. | 2011 | Details |
| A49022 | 21112115 | J Hepatol | Insulin resistance and oxidative stress: two therapeutic targets in non-alcoholic steatohepatitis. | 2010 | Details |
| A49023 | 21103235 | Case Rep Gastroenterol | Non-Alcoholic Steatohepatitis in Myotonic Dystrophy: DMPK Gene Mutation, Insulin Resistance and Development of Steatohepatitis. | 2010 | Details |
| A49026 | 20977462 | Br J Pharmacol | Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase. | 2010 | Details |
| A49028 | 20953861 | Diabetologia | Targeting energy expenditure via fuel switching and beyond. | 2010 | Details |
| A49036 | 20570793 | Orv Hetil | [Role of environmental factors in the etiology of hepatocellular carcinoma]. | 2010 | Details |