Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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apoptosis249 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0001 | DB00002 | approved | biotech | Cetuximab | Therapeutic strategy associated | Details |
| R0006 | DB00016 | approved | biotech | Erythropoietin | Therapeutic strategy associated | Details |
| R0008 | DB00022 | approved | biotech | Peginterferon alfa-2b | Therapeutic strategy associated | Details |
| R0020 | DB00065 | approved | biotech | Infliximab | Therapeutic strategy associated | Details |
| R0022 | DB00073 | approved | biotech | Rituximab | Therapeutic strategy associated | Details |
| R0024 | DB00081 | approved; investigational | biotech | Tositumomab | Therapeutic strategy associated | Details |
| R0028 | DB00098 | approved | biotech | Antithymocyte immunoglobulin (rabbit) | Therapeutic strategy associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0070 | DB00188 | approved; investigational | small molecule | Bortezomib | Therapeutic strategy associated | Details |
| R0088 | DB00227 | approved; investigational | small molecule | Lovastatin | Therapeutic strategy associated | Details |
| R0096 | DB00261 | approved | small molecule | Anagrelide | Therapeutic strategy associated | Details |
| R0104 | DB00282 | approved | small molecule | Pamidronic acid | Therapeutic strategy associated | Details |
| R0129 | DB00360 | approved; investigational | small molecule | Sapropterin | Therapeutic strategy associated | Details |
| R0130 | DB00361 | approved; investigational | small molecule | Vinorelbine | Therapeutic strategy associated | Details |
| R0141 | DB00399 | approved | small molecule | Zoledronic acid | Therapeutic strategy associated | Details |
| R0149 | DB00441 | approved | small molecule | Gemcitabine | Therapeutic strategy associated | Details |
| R0150 | DB00443 | approved; vet_approved | small molecule | Betamethasone | Therapeutic strategy associated | Details |
| R0163 | DB00480 | approved | small molecule | Lenalidomide | Therapeutic strategy associated | Details |
| R0164 | DB00481 | approved; investigational | small molecule | Raloxifene | Therapeutic strategy associated | Details |
| R0182 | DB00539 | approved; investigational | small molecule | Toremifene | Therapeutic strategy associated | Details |
| R0196 | DB00571 | approved; investigational | small molecule | Propranolol | Therapeutic strategy associated | Details |
| R0204 | DB00590 | approved | small molecule | Doxazosin | Therapeutic strategy associated | Details |
| R0208 | DB00596 | approved | small molecule | Ulobetasol | Therapeutic strategy associated | Details |
| R0211 | DB00603 | approved; investigational | small molecule | Medroxyprogesterone acetate | Therapeutic strategy associated | Details |
| R0218 | DB00619 | approved | small molecule | Imatinib | Therapeutic strategy associated | Details |
| R0223 | DB00630 | approved | small molecule | Alendronic acid | Therapeutic strategy associated | Details |
| R0224 | DB00631 | approved; investigational | small molecule | Clofarabine | Therapeutic strategy associated | Details |
| R0225 | DB00635 | approved; vet_approved | small molecule | Prednisone | Therapeutic strategy associated | Details |
| R0236 | DB00675 | approved | small molecule | Tamoxifen | Therapeutic strategy associated | Details |
| R0249 | DB00710 | approved; investigational | small molecule | Ibandronate | Therapeutic strategy associated | Details |
| R0254 | DB00724 | approved; investigational | small molecule | Imiquimod | Therapeutic strategy associated | Details |
| R0261 | DB00741 | approved; vet_approved | small molecule | Hydrocortisone | Therapeutic strategy associated | Details |
| R0269 | DB00762 | approved; investigational | small molecule | Irinotecan | Therapeutic strategy associated | Details |
| R0275 | DB00773 | approved | small molecule | Etoposide | Therapeutic strategy associated | Details |
| R0289 | DB00811 | approved | small molecule | Ribavirin | Therapeutic strategy associated | Details |
| R0293 | DB00820 | approved; investigational | small molecule | Tadalafil | Therapeutic strategy associated | Details |
| R0309 | DB00853 | approved; investigational | small molecule | Temozolomide | Therapeutic strategy associated | Details |
| R0311 | DB00860 | approved; vet_approved | small molecule | Prednisolone | Therapeutic strategy associated | Details |
| R0324 | DB00884 | approved; investigational | small molecule | Risedronic acid | Therapeutic strategy associated | Details |
| R0345 | DB00959 | approved; vet_approved | small molecule | Methylprednisolone | Therapeutic strategy associated | Details |
| R0354 | DB00982 | approved | small molecule | Isotretinoin | Therapeutic strategy associated | Details |
| R0357 | DB00993 | approved | small molecule | Azathioprine | Therapeutic strategy associated | Details |
| R0359 | DB00995 | approved; investigational | small molecule | Auranofin | Therapeutic strategy associated | Details |
| R0365 | DB01008 | approved; investigational | small molecule | Busulfan | Therapeutic strategy associated | Details |
| R0368 | DB01013 | approved | small molecule | Clobetasol propionate | Therapeutic strategy associated | Details |
| R0378 | DB01030 | approved; investigational | small molecule | Topotecan | Therapeutic strategy associated | Details |
| R0380 | DB01034 | experimental | small molecule | Cerulenin | Therapeutic strategy associated | Details |
| R0385 | DB01050 | approved | small molecule | Ibuprofen | Target associated | Details |
| R0388 | DB01055 | experimental | small molecule | Mimosine | Therapeutic strategy associated | Details |
| R0403 | DB01097 | approved; investigational | small molecule | Leflunomide | Therapeutic strategy associated | Details |
| R0407 | DB01110 | approved; investigational; vet_approved | small molecule | Miconazole | Therapeutic strategy associated | Details |
| R0417 | DB01126 | approved; investigational | small molecule | Dutasteride | Therapeutic strategy associated | Details |
| R0424 | DB01143 | approved; investigational | small molecule | Amifostine | Therapeutic strategy associated | Details |
| R0431 | DB01162 | approved | small molecule | Terazosin | Therapeutic strategy associated | Details |
| R0432 | DB01169 | approved; investigational | small molecule | Arsenic trioxide | Therapeutic strategy associated | Details |
| R0443 | DB01196 | approved; investigational | small molecule | Estramustine | Therapeutic strategy associated | Details |
| R0453 | DB01222 | approved | small molecule | Budesonide | Therapeutic strategy associated | Details |
| R0458 | DB01229 | approved; vet_approved | small molecule | Paclitaxel | Therapeutic strategy associated | Details |
| R0460 | DB01234 | approved; investigational; vet_approved | small molecule | Dexamethasone | Therapeutic strategy associated | Details |
| R0465 | DB01248 | approved; investigational | small molecule | Docetaxel | Therapeutic strategy associated | Details |
| R0471 | DB01269 | approved; investigational | biotech | Panitumumab | Therapeutic strategy associated | Details |
| R0477 | DB01280 | approved; investigational | small molecule | Nelarabine | Therapeutic strategy associated | Details |
| R0505 | DB01380 | approved; investigational | small molecule | Cortisone acetate | Therapeutic strategy associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0536 | DB01590 | approved | small molecule | Everolimus | Therapeutic strategy associated | Details |
| R0566 | DB02546 | approved; investigational | small molecule | Vorinostat | Therapeutic strategy associated | Details |
| R0573 | DB03010 | experimental; investigational | small molecule | Patupilone | Therapeutic strategy associated | Details |
| R0585 | DB03496 | experimental; investigational | small molecule | Alvocidib | Therapeutic strategy associated | Details |
| R0596 | DB04209 | approved; investigational | small molecule | Dequalinium | Therapeutic strategy associated | Details |
| R0600 | DB04339 | approved; investigational | small molecule | Carbocisteine | Therapeutic strategy associated | Details |
| R0612 | DB04690 | experimental | small molecule | Camptothecin | Therapeutic strategy associated | Details |
| R0635 | DB04874 | investigational | small molecule | Picoplatin | Therapeutic strategy associated | Details |
| R0642 | DB04900 | investigational | biotech | Thymalfasin | Therapeutic strategy associated | Details |
| R0644 | DB04915 | investigational | small molecule | Idronoxil | Therapeutic strategy associated | Details |
| R0656 | DB04944 | investigational | small molecule | Acadesine | Therapeutic strategy associated | Details |
| R0657 | DB04949 | investigational | biotech | Pexelizumab | Therapeutic strategy associated | Details |
| R0665 | DB04974 | investigational | small molecule | Rimiducid | Therapeutic strategy associated | Details |
| R0666 | DB04977 | investigational | small molecule | Plitidepsin | Therapeutic strategy associated | Details |
| R0669 | DB04985 | investigational | biotech | Tigapotide | Therapeutic strategy associated | Details |
| R0672 | DB04999 | investigational | small molecule | MBO7133 | Therapeutic strategy associated | Details |
| R0674 | DB05003 | investigational | small molecule | Imexon | Therapeutic strategy associated | Details |
| R0676 | DB05015 | approved; investigational | small molecule | Belinostat | Therapeutic strategy associated | Details |
| R0686 | DB05051 | investigational | small molecule | BZL101 | Therapeutic strategy associated | Details |
| R0693 | DB05075 | investigational | small molecule | TG-100801 | Therapeutic strategy associated | Details |
| R0702 | DB05103 | investigational | small molecule | AN-9 | Therapeutic strategy associated | Details |
| R0710 | DB05126 | investigational | small molecule | PYM50018 | Therapeutic strategy associated | Details |
| R0715 | DB05140 | investigational | biotech | RAV12 | Therapeutic strategy associated | Details |
| R0716 | DB05141 | investigational | small molecule | LY2181308 | Therapeutic strategy associated | Details |
| R0723 | DB05170 | investigational | small molecule | Benzimate | Therapeutic strategy associated | Details |
| R0728 | DB05189 | investigational | small molecule | EPC2407 | Therapeutic strategy associated | Details |
| R0731 | DB05198 | investigational | small molecule | CYC116 | Therapeutic strategy associated | Details |
| R0736 | DB05204 | investigational | small molecule | XL418 | Therapeutic strategy associated | Details |
| R0743 | DB05223 | investigational | small molecule | Pracinostat | Therapeutic strategy associated | Details |
| R0751 | DB05241 | investigational | small molecule | XL765 | Therapeutic strategy associated | Details |
| R0755 | DB05260 | approved; investigational | small molecule | Gallium nitrate | Therapeutic strategy associated | Details |
| R0759 | DB05282 | investigational | small molecule | MCC | Therapeutic strategy associated | Details |
| R0761 | DB05297 | investigational | small molecule | Paclitaxel docosahexaenoic acid | Therapeutic strategy associated | Details |
| R0765 | DB05305 | investigational | biotech | Cintredekin besudotox | Therapeutic strategy associated | Details |
| R0770 | DB05319 | investigational | biotech | Oportuzumab monatox | Therapeutic strategy associated | Details |
| R0779 | DB05387 | investigational | small molecule | AE-941 | Therapeutic strategy associated | Details |