Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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oxidative stress50 records.
Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
---|---|---|---|---|---|---|
R0041 | DB00130 | approved; investigational; nutraceutical | small molecule | L-Glutamine | Therapeutic strategy associated | Details |
R0044 | DB00134 | approved; nutraceutical | small molecule | Methionine | Therapeutic strategy associated | Details |
R0045 | DB00137 | approved; investigational; nutraceutical | small molecule | Lutein | Therapeutic strategy associated | Details |
R0046 | DB00138 | approved; nutraceutical | small molecule | Cystine | Therapeutic strategy associated | Details |
R0053 | DB00152 | approved; investigational; nutraceutical; vet_approved | small molecule | Thiamine | Therapeutic strategy associated | Details |
R0065 | DB00178 | approved | small molecule | Ramipril | Therapeutic strategy associated | Details |
R0088 | DB00227 | approved; investigational | small molecule | Lovastatin | Therapeutic strategy associated | Details |
R0227 | DB00641 | approved | small molecule | Simvastatin | Therapeutic strategy associated | Details |
R0243 | DB00694 | approved | small molecule | Daunorubicin | Therapeutic strategy associated | Details |
R0288 | DB00808 | approved | small molecule | Indapamide | Therapeutic strategy associated | Details |
R0359 | DB00995 | approved; investigational | small molecule | Auranofin | Therapeutic strategy associated | Details |
R0385 | DB01050 | approved | small molecule | Ibuprofen | Target associated | Details |
R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
R0626 | DB04854 | approved | small molecule | Febuxostat | Therapeutic strategy associated | Details |
R0629 | DB04861 | approved; investigational | small molecule | Nebivolol | Therapeutic strategy associated | Details |
R0829 | DB05533 | investigational | small molecule | QR-333 | Therapeutic strategy associated | Details |
R0843 | DB05660 | investigational | small molecule | D-JNKI-1 | Therapeutic strategy associated | Details |
R0852 | DB05719 | investigational | small molecule | Elesclomol | Therapeutic strategy associated | Details |
R0911 | DB05983 | investigational | small molecule | Bardoxolone methyl | Therapeutic strategy associated | Details |
R0929 | DB06137 | approved; investigational | small molecule | Tirbanibulin | Therapeutic strategy associated | Details |
R0933 | DB06154 | approved | small molecule | Pentaerythritol tetranitrate | Therapeutic strategy associated | Details |
R0958 | DB06250 | investigational | small molecule | Fluasterone | Therapeutic strategy associated | Details |
R0997 | DB06376 | investigational | small molecule | CHGN111 | Therapeutic strategy associated | Details |
R1091 | DB06755 | approved; nutraceutical | small molecule | Beta carotene | Therapeutic strategy associated | Details |
R1107 | DB06824 | approved; investigational | small molecule | Triethylenetetramine | Therapeutic strategy associated | Details |
R1167 | DB08838 | experimental | small molecule | Agmatine | Therapeutic strategy associated | Details |
R1168 | DB08842 | approved; investigational | small molecule | Acetylcarnitine | Therapeutic strategy associated | Details |
R1169 | DB08844 | investigational | small molecule | Uric acid | Therapeutic strategy associated | Details |
R1184 | DB08908 | approved; investigational | small molecule | Dimethyl fumarate | Therapeutic strategy associated | Details |
R1190 | DB08949 | approved; withdrawn | small molecule | Inositol nicotinate | Therapeutic strategy associated | Details |
R1191 | DB08995 | approved; investigational | small molecule | Diosmin | Therapeutic strategy associated | Details |
R1302 | DB09338 | experimental | small molecule | Mersalyl | Therapeutic strategy associated | Details |
R1327 | DB11068 | approved | small molecule | Selenic acid | Therapeutic strategy associated | Details |
R1352 | DB11217 | approved | small molecule | Arbutin | Therapeutic strategy associated | Details |
R1367 | DB11333 | approved; investigational | small molecule | Poloxamer 188 | Therapeutic strategy associated | Details |
R1381 | DB11590 | approved | small molecule | Thimerosal | Therapeutic strategy associated | Details |
R1439 | DB12243 | approved; investigational | small molecule | Edaravone | Therapeutic strategy associated | Details |
R1441 | DB12281 | approved; investigational | biotech | Luspatercept | Therapeutic strategy associated | Details |
R1442 | DB12328 | approved; investigational | small molecule | Cantharidin | Therapeutic strategy associated | Details |
R1458 | DB12651 | investigational | small molecule | Bardoxolone | Therapeutic strategy associated | Details |
R1471 | DB12965 | approved; investigational | small molecule | Silver | Therapeutic strategy associated | Details |
R1475 | DB13145 | approved; investigational | small molecule | Nedaplatin | Therapeutic strategy associated | Details |
R1499 | DB13906 | experimental | biotech | Aloe vera leaf | Therapeutic strategy associated | Details |
R1505 | DB13949 | approved | small molecule | Ferric cation | Therapeutic strategy associated | Details |
R1508 | DB14001 | approved; nutraceutical; vet_approved | small molecule | alpha-Tocopherol succinate | Therapeutic strategy associated | Details |
R1509 | DB14002 | approved; nutraceutical; vet_approved | small molecule | D-alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
R1510 | DB14003 | approved | small molecule | alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
R1518 | DB14487 | approved; investigational | small molecule | Zinc acetate | Therapeutic strategy associated | Details |
R1543 | DB14783 | approved; investigational | small molecule | Diroximel fumarate | Therapeutic strategy associated | Details |
R1573 | DB15726 | investigational | biotech | Human Umbilical Cord Mesenchymal Stem Cells | Therapeutic strategy associated | Details |