Investigational Drugs
Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.
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581 records.
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D153 | Gliclazide | Chemical drug | DB01120 | VEGFA other/unknown | Antidiabetic drug | Under clinical trials | Details |
| D154 | Glimepiride | Chemical drug | DB00222 | ABCC8 binder; KCNJ1 inhibitor; KCNJ11 inhibitor; KCNJ11 potassium channel inhibitor | Antidiabetic drug | Under clinical trials | Details |
| D155 | Glucagon | Biological drug | DB00040 | GCGR agonist | Antidiabetic drug | Under clinical trials | Details |
| D156 | Glucomannan | Chemical drug | DB14963 | -- | Anorexic | Under clinical trials | Details |
| D157 | Glucophage | Chemical drug | DB00331 | -- | -- | Under clinical trials | Details |
| D158 | Glutathione | Chemical drug | DB00143 | MGST3; HPGDS; GSTM2; GSTM5; GPX7 cofactor; MGST2; GSS; GSTM1; GSTK1; GSTM3; GSTM4; GPX1 cofactor; GPX2 cofactor; GPX3 cofactor | -- | Under clinical trials | Details |
| D159 | Green Cardamom | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D160 | Growth Hormone | Biological drug | DB00052 | GHR ligand; PRLR ligand | -- | Under clinical trials | Details |
| D161 | HEC96719 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D162 | Hedan Capsule | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D163 | Hepafast | Miscellany | -- | -- | -- | Under clinical trials | Details |
| D164 | Hepaguard | Herbal medicine | -- | -- | -- | Failed in clinical trials | Details |
| D165 | Hepar-P | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D166 | HepaStem | Biological drug | -- | -- | Cell therapy drug | Under clinical trials | Details |
| D167 | Hepatoheal tablet | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D168 | Hepaxa | Supplement | -- | -- | -- | Under clinical trials | Details |
| D169 | Hesperidin | Chemical drug | DB04703 | AURKB | Antiosteoporotic drug | Under clinical trials | Details |
| D170 | HL Tablet | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D171 | HM15211 | Biological drug | -- | GLP-1 agonist; GIP agonist; Glucagon triple agonist | Improve insulin resistance | Under clinical trials | Details |
| D172 | Hoodia Gordonii | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D173 | HPN-01 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D174 | HTD1801 | Chemical drug | -- | lipid modulator | Anticholesteremic; Anti-inflammatories; Antihyperlipidaemics; Hepatoprotectants | Under clinical trials | Details |
| D175 | Hydroalcoholic extract of Berberis fruits integerrima | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D176 | Hydrolyzed oyster extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D177 | Hydroxy citric acid | Chemical drug | DB04272 | PGLS; HGS; CS; RTCA; CS; APRT; LYZ | -- | Under clinical trials | Details |
| D178 | Hydroxytyrosol | Chemical drug | DB12771 | -- | Antioxidant | Under clinical trials | Details |
| D179 | Icosabutate | Chemical drug | DB12990 | -- | -- | Under clinical trials | Details |
| D180 | IdB 1016 | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D181 | IMM-124E | Biological drug | -- | LPS | Gut microbiome modulator | Under clinical trials | Details |
| D182 | Insulin | Biological drug | DB00030 | INSR agonist; CPE modulator&product of | -- | Under clinical trials | Details |
| D183 | Insulin Glargine | Biological drug | DB00047 | INSR agonist | Antidiabetic drug | Under clinical trials | Details |
| D184 | INT-767 | Chemical drug | -- | FXR agonist; TGR5 agonist | Enhance lipid metabolism | Under investigation | Details |
| D185 | Inulin | Chemical drug | DB00638 | CFT binder | -- | Under clinical trials | Details |
| D186 | ION 224 | Miscellany | -- | DGAT2 inhibitor | Enhance lipid metabolism | Under clinical trials | Details |
| D187 | Ipragliflozin | Chemical drug | DB11698 | SGLT2 inhibitor | Improve insulin resistance | Under clinical trials | Details |
| D188 | ISIS 703802 | Biological drug | -- | -- | Anticholesteremic drug | Under clinical trials | Details |
| D189 | Itraconazole | Chemical drug | DB01167 | P450 inhibitor | -- | Under clinical trials | Details |
| D190 | Japanese apricot extract | Biological extract | -- | -- | -- | Failed in clinical trials | Details |
| D191 | Jiuwei Qingzhi Gao | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D192 | JKB-121 | Chemical drug | DB06230 | TLR4 antagonist | Anti-inflammatory | Under clinical trials | Details |
| D193 | JKB-122 | Miscellany | -- | TLR4 antagonist | Anti-inflammatory | Under clinical trials | Details |
| D194 | Katuki churna | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D195 | Kestose | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D196 | Lactobacillus acidophilus | Biological drug | DB15823 | -- | -- | Under clinical trials | Details |
| D197 | Lactobacillus spp | Supplement | -- | -- | -- | Under clinical trials | Details |
| D198 | Lactulose | Chemical drug | DB00581 | -- | -- | Under clinical trials | Details |
| D199 | L-alanine | Chemical drug | DB00160 | KYNU | -- | Failed in clinical trials | Details |
| D200 | Lanifibranor | Chemical drug | DB14801 | PPARD agonist; PPARA agonist; PPARG agonist | Dermatological drug | Advanced in clinical trials | Details |
| D201 | L-Carnitine | Supplement | DB00583 | SLC22A4; SLC22A5; CRAT; MPO | -- | Under clinical trials | Details |
| D202 | LCQ908 | Chemical drug | DB12866 | DGAT1 inhibitor | Hypolipidemic drug | Under clinical trials | Details |