Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24328 | 22996622 | Hepatology | Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause? | 2013 | Details |
| A24339 | 22986486 | Endocr J | Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver. | 2012 | Details |
| A24342 | 22983378 | J Pediatr Gastroenterol Nutr | Serum retinol-binding protein 4 is independently associated with pediatric NAFLD and fasting triglyceride level. | 2013 | Details |
| A24345 | 22981383 | Biochem Pharmacol | Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. | 2012 | Details |
| A24347 | 22980050 | Best Pract Res Clin Endocrinol Metab | Glucocorticoids as mediators of developmental programming effects. | 2012 | Details |
| A24351 | 22977624 | Exp Ther Med | Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease. | 2011 | Details |
| A24352 | 22975640 | Clin Biochem | Combinative analysis of factors influence serum alanine aminotransferase activity in adult male population from southern China. | 2012 | Details |
| A24353 | 22974598 | J Pediatr Surg | Patterns of surgical weight loss and resolution of metabolic abnormalities in superobese bariatric adolescents. | 2012 | Details |
| A24359 | 22969777 | Cardiorenal Med | Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy. | 2012 | Details |
| A24360 | 22969728 | Front Physiol | A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells. | 2012 | Details |
| A24363 | 22966224 | PPAR Res | Update on pparγ and nonalcoholic Fatty liver disease. | 2012 | Details |
| A24364 | 22965160 | Horm Res Paediatr | Consequences of stopping and restarting leptin in an adolescent with lipodystrophy. | 2012 | Details |
| A24365 | 22964849 | Lab Invest | Stimulation of fat accumulation in hepatocytes by PGE₂-dependent repression of hepatic lipolysis, β-oxidation and VLDL-synthesis. | 2012 | Details |
| A24367 | 22964692 | Clin Ter | [Relation of non-alcoholic hepatic steatosis to early carotid atherosclerosis in diet-controlled impaired glucose tolerance subjects]. | 2012 | Details |
| A24368 | 22964626 | Digestion | High prevalence of gastroesophageal reflux symptoms in patients with non-alcoholic fatty liver disease associated with serum levels of triglyceride and cholesterol but not simple visceral obesity. | 2012 | Details |
| A24372 | 22962039 | Pediatr Obes | Analysis of adipokine concentrations in paediatric non-alcoholic fatty liver disease. | 2012 | Details |
| A24374 | 22960889 | Indian J Med Res | Association of pro-inflammatory cytokines, adipokines & oxidative stress with insulin resistance & non-alcoholic fatty liver disease. | 2012 | Details |
| A24375 | 22960565 | J Proteomics | Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin. | 2012 | Details |
| A24376 | 22959976 | Arch Med Res | Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population. | 2012 | Details |
| A24378 | 22958053 | Aliment Pharmacol Ther | Non-alcoholic fatty liver disease (NAFLD) is associated with low level of physical activity: a population-based study. | 2012 | Details |
| A24379 | 22955994 | Diabetologia | Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance. | 2012 | Details |
| A24383 | 22952059 | Mol Med | Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response. | 2012 | Details |
| A24385 | 22950627 | Scand J Clin Lab Invest | A novel appetite peptide, nesfatin-1 in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24386 | 22950055 | Diabetes Metab J | GLP-1 Receptor Agonist and Non-Alcoholic Fatty Liver Disease. | 2012 | Details |
| A24387 | 22949894 | Case Rep Gastroenterol | Dipeptidyl Peptidase IV Inhibitor Improves Insulin Resistance and Steatosis in a Refractory Nonalcoholic Fatty Liver Disease Patient: A Case Report. | 2012 | Details |
| A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
| A24393 | 22940046 | J Hepatol | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. | 2012 | Details |
| A24394 | 22940028 | Phytomedicine | Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells. | 2012 | Details |
| A24398 | 22935341 | Nutr Res | The lipid accumulation product is highly related to serum alanine aminotransferase level in male adults. | 2012 | Details |
| A24401 | 22934096 | Front Immunol | Resolution of inflammation in obesity-induced liver disease. | 2012 | Details |
| A24402 | 22934006 | Front Physiol | Liver fibrogenesis in non-alcoholic steatohepatitis. | 2012 | Details |
| A24403 | 22933860 | Gastroenterol Hepatol (N Y) | Hepatitis C virus infection and nonalcoholic steatohepatitis. | 2012 | Details |
| A24405 | 22932913 | Horm Metab Res | Reversion of steatosis by SREBP-1c antisense oligonucleotide did not improve hepatic insulin action in diet-induced obesity mice. | 2012 | Details |
| A24406 | 22932160 | Eur J Gastroenterol Hepatol | Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents. | 2012 | Details |
| A24419 | 22918684 | Dig Dis Sci | Dipeptidyl peptidase 4-deficient rats have improved bile secretory function in high fat diet-induced steatosis. | 2012 | Details |
| A24422 | 22913901 | Postgrad Med | Managing diabetes in patients with chronic liver disease. | 2012 | Details |
| A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
| A24429 | 22903613 | Endocrinology | Hepatic insulin signaling changes: possible mechanism in prenatal hypoxia-increased susceptibility of fatty liver in adulthood. | 2012 | Details |
| A24431 | 22902548 | J Hepatol | Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. | 2012 | Details |
| A24434 | 22899407 | Georgian Med News | [Treatment of nonalcogolic fatty disease of liver]. | 2012 | Details |
| A24435 | 22899406 | Georgian Med News | [Peculiarities of metabolic syndrome and nonalcogolic fatty liver disease in menopausal women]. | 2012 | Details |
| A24437 | 22898281 | Zhongguo Dang Dai Er Ke Za Zhi | [Quantitative assessment of intrahepatic fat content in children and adolescents with non-alcoholic fatty liver disease]. | 2012 | Details |
| A24438 | 22893453 | Endocr J | Fatty liver as a consequence and cause of insulin resistance: lessons from type 2 diabetic liver. | 2012 | Details |
| A24439 | 22892494 | Intern Med | Long-term branched-chain amino acid supplementation improves glucose tolerance in patients with nonalcoholic steatohepatitis-related cirrhosis. | 2012 | Details |
| A24452 | 22878918 | Dig Dis Sci | Probucol ameliorates the development of nonalcoholic steatohepatitis in rats fed high-fat diets. | 2012 | Details |
| A24455 | 22876924 | Curr Med Chem | Adiponectin: key player in the adipose tissue-liver crosstalk. | 2012 | Details |
| A24458 | 22876038 | World J Gastroenterol | Moro orange juice prevents fatty liver in mice. | 2012 | Details |
| A24459 | 22876027 | World J Gastroenterol | Diagnostic and therapeutic implications of the association between ferritin level and severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A24460 | 22876026 | World J Gastroenterol | Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome. | 2012 | Details |
| A24461 | 22875138 | Pediatr Cardiol | The relationship between pediatric nonalcoholic fatty liver disease and cardiovascular risk factors and increased risk of atherosclerosis in obese children. | 2012 | Details |
| A24469 | 22864348 | Yakugaku Zasshi | [Retinoids as promising treatment for non-alcoholic fatty liver disease]. | 2012 | Details |
| A24472 | 22863080 | Liver Int | α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. | 2012 | Details |
| A24476 | 22855698 | World J Hepatol | Lifestyle intervention in non-alcoholic fatty liver disease in Chengyang District, Qingdao, China. | 2012 | Details |
| A24477 | 22855696 | World J Hepatol | Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24479 | 22854109 | Metabolism | High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice. | 2012 | Details |
| A24483 | 22849970 | Br J Nutr | Beneficial effect of a weight-stable, low-fat/low-saturated fat/low-glycaemic index diet to reduce liver fat in older subjects. | 2012 | Details |
| A24484 | 22848440 | PLoS One | Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24486 | 22846856 | Semin Oncol | Causes of and prevention strategies for hepatocellular carcinoma. | 2012 | Details |
| A24498 | 22837189 | J Clin Endocrinol Metab | Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance. | 2012 | Details |
| A24500 | 22829522 | Diabetes Care | Fatty liver, insulin resistance, and features of metabolic syndrome: relationships with coronary artery calcium in 10,153 people. | 2012 | Details |
| A24501 | 22829450 | Diabetes | Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly. | 2012 | Details |
| A24507 | 22824483 | Clin Liver Dis | The cardiovascular link to nonalcoholic fatty liver disease: a critical analysis. | 2012 | Details |
| A24508 | 22824482 | Clin Liver Dis | Is nonalcoholic fatty liver disease in children the same disease as in adults? | 2012 | Details |
| A24511 | 22824479 | Clin Liver Dis | A myriad of pathways to NASH. | 2012 | Details |
| A24512 | 22824478 | Clin Liver Dis | Mechanisms of simple hepatic steatosis: not so simple after all. | 2012 | Details |
| A24520 | 22819708 | Eur J Pharmacol | Alpha-lipoic acid induces adipose triglyceride lipase expression and decreases intracellular lipid accumulation in HepG2 cells. | 2012 | Details |
| A24524 | 22809960 | Dig Liver Dis | Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance. | 2012 | Details |
| A24525 | 22809102 | Annu Rev Nutr | Endoplasmic reticulum stress in nonalcoholic fatty liver disease. | 2012 | Details |
| A24527 | 22807031 | Diabetes | Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. | 2012 | Details |
| A24528 | 22806626 | Hepatology | Deficiency of carboxylesterase 1/esterase-x results in obesity, hepatic steatosis, and hyperlipidemia. | 2012 | Details |
| A24532 | 22796347 | Nutr Metab Cardiovasc Dis | Ambulatory arterial stiffness indices and non-alcoholic fatty liver disease in essential hypertension. | 2012 | Details |
| A24535 | 22795319 | Clin Res Hepatol Gastroenterol | Does fructose consumption contribute to non-alcoholic fatty liver disease? | 2012 | Details |
| A24536 | 22792295 | PLoS One | The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation. | 2012 | Details |
| A24539 | 22789032 | Clin Endocrinol (Oxf) | Fatty liver and insulin resistance in children with hypobetalipoproteinemia: the importance of aetiology. | 2013 | Details |
| A24540 | 22788090 | Rom J Intern Med | Non-alcoholic fatty liver disease and the statins treatment. | 2012 | Details |
| A24543 | 22770622 | Expert Opin Pharmacother | The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges. | 2012 | Details |
| A24548 | 22768070 | PLoS One | Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice. | 2012 | Details |
| A24553 | 22753171 | Hepatology | Elovl6 promotes nonalcoholic steatohepatitis. | 2012 | Details |
| A24554 | 22753133 | Hepatology | Liver vitamin D receptor, CYP2R1, and CYP27A1 expression: relationship with liver histology and vitamin D3 levels in patients with nonalcoholic steatohepatitis or hepatitis C virus. | 2012 | Details |
| A24556 | 22751700 | Diabetes | Toll-like receptor 4 deficiency promotes the alternative activation of adipose tissue macrophages. | 2012 | Details |
| A24557 | 22751691 | Diabetes | Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. | 2012 | Details |
| A24562 | 22749135 | J Nutr Biochem | The role of dietary fatty acids in the pathology of metabolic syndrome. | 2012 | Details |
| A24563 | 22748277 | Atherosclerosis | Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in Asian Indians. | 2012 | Details |
| A24567 | 22742899 | Eur J Pharmacol | Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. | 2012 | Details |
| A24568 | 22741595 | J Gastroenterol Hepatol | Prevalence and risk factors for non-alcoholic fatty liver disease in Asian people who are not obese. | 2012 | Details |
| A24572 | 22738690 | J Cardiol | The association between impaired collateral circulation and non-alcoholic fatty liver in patients with severe coronary artery disease. | 2012 | Details |
| A24575 | 22735605 | Eur J Gastroenterol Hepatol | How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A24576 | 22735219 | Rev Assoc Med Bras (1992) | Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals. | 2013 | Details |
| A24577 | 22734967 | Clin Sci (Lond) | Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. | 2012 | Details |
| A24579 | 22730920 | Aliment Pharmacol Ther | Review article: non-alcoholic fatty liver disease and osteoporosis--clinical and molecular crosstalk. | 2012 | Details |
| A24585 | 22722431 | Dig Dis | Nonalcoholic fatty liver disease/steatohepatitis: epidemiology, pathogenesis, clinical presentation and treatment. | 2012 | Details |
| A24586 | 22720311 | J Gastrointestin Liver Dis | Is visceral fat reduction necessary to favour metabolic changes in the liver? | 2012 | Details |
| A24590 | 22718512 | Mol Biol Rep | Traditional Chinese medicines benefit to nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2012 | Details |
| A24591 | 22717644 | Endocrinol Nutr | [Non-alcoholic fatty liver disease and its association with clinical and biochemical variables in obese children and adolescents: effect of a one-year intervention on lifestyle]. | 2012 | Details |
| A24592 | 22717200 | J Acad Nutr Diet | The role of diet and nutrient composition in nonalcoholic Fatty liver disease. | 2012 | Details |
| A24595 | 22713601 | Lipids Health Dis | Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats. | 2012 | Details |
| A24597 | 22710359 | Int J Mol Med | Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: analysis of isolated hepatic stellate cells. | 2012 | Details |
| A24600 | 22706738 | Turk J Gastroenterol | Effects of probiotics on methionine choline deficient diet-induced steatohepatitis in rats. | 2012 | Details |
| A24604 | 22700629 | Ann Hepatol |  Correlation of adipose tissue with liver histology in Asian Indian patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24607 | 22698815 | Toxicol Lett | Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice. | 2012 | Details |