Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Intestinal161 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0041 | DB00130 | approved; investigational; nutraceutical | small molecule | L-Glutamine | Therapeutic strategy associated | Details |
| R0049 | DB00146 | approved; nutraceutical | small molecule | Calcifediol | Indication associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0071 | DB00193 | approved; investigational | small molecule | Tramadol | Therapeutic strategy associated | Details |
| R0073 | DB00199 | approved; investigational; vet_approved | small molecule | Erythromycin | Indication associated | Details |
| R0074 | DB00201 | approved | small molecule | Caffeine | Indication associated | Details |
| R0093 | DB00244 | approved | small molecule | Mesalazine | Therapeutic strategy associated | Details |
| R0094 | DB00250 | approved; investigational | small molecule | Dapsone | Therapeutic strategy associated | Details |
| R0096 | DB00261 | approved | small molecule | Anagrelide | Therapeutic strategy associated | Details |
| R0116 | DB00326 | approved | small molecule | Calcium glucoheptonate | Indication associated | Details |
| R0117 | DB00328 | approved; investigational | small molecule | Indomethacin | Therapeutic strategy associated | Details |
| R0118 | DB00333 | approved | small molecule | Methadone | Therapeutic strategy associated | Details |
| R0150 | DB00443 | approved; vet_approved | small molecule | Betamethasone | Therapeutic strategy associated | Details |
| R0157 | DB00465 | approved | small molecule | Ketorolac | Therapeutic strategy associated | Details |
| R0165 | DB00482 | approved; investigational | small molecule | Celecoxib | Therapeutic strategy associated | Details |
| R0167 | DB00487 | approved | small molecule | Pefloxacin | Indication associated | Details |
| R0169 | DB00491 | approved | small molecule | Miglitol | Indication associated | Details |
| R0170 | DB00492 | approved | small molecule | Fosinopril | Indication associated | Details |
| R0172 | DB00500 | approved | small molecule | Tolmetin | Therapeutic strategy associated | Details |
| R0197 | DB00573 | approved | small molecule | Fenoprofen | Target associated | Details |
| R0202 | DB00586 | approved; vet_approved | small molecule | Diclofenac | Therapeutic strategy associated | Details |
| R0212 | DB00605 | approved; investigational | small molecule | Sulindac | Therapeutic strategy associated | Details |
| R0214 | DB00608 | approved; investigational; vet_approved | small molecule | Chloroquine | Target associated | Details |
| R0218 | DB00619 | approved | small molecule | Imatinib | Therapeutic strategy associated | Details |
| R0225 | DB00635 | approved; vet_approved | small molecule | Prednisone | Therapeutic strategy associated | Details |
| R0230 | DB00657 | approved; investigational | small molecule | Mecamylamine | Therapeutic strategy associated | Details |
| R0233 | DB00668 | approved; vet_approved | small molecule | Epinephrine | Target associated | Details |
| R0239 | DB00688 | approved; investigational | small molecule | Mycophenolate mofetil | Therapeutic strategy associated | Details |
| R0261 | DB00741 | approved; vet_approved | small molecule | Hydrocortisone | Therapeutic strategy associated | Details |
| R0274 | DB00771 | approved | small molecule | Clidinium | Indication associated | Details |
| R0281 | DB00788 | approved; vet_approved | small molecule | Naproxen | Therapeutic strategy associated | Details |
| R0282 | DB00795 | approved | small molecule | Sulfasalazine | Therapeutic strategy associated | Details |
| R0283 | DB00796 | approved | small molecule | Candesartan cilexetil | Target associated | Details |
| R0291 | DB00814 | approved; vet_approved | small molecule | Meloxicam | Therapeutic strategy associated | Details |
| R0294 | DB00821 | approved; vet_approved; withdrawn | small molecule | Carprofen | Therapeutic strategy associated | Details |
| R0301 | DB00836 | approved | small molecule | Loperamide | Therapeutic strategy associated | Details |
| R0306 | DB00845 | approved; investigational | small molecule | Clofazimine | Therapeutic strategy associated | Details |
| R0311 | DB00860 | approved; vet_approved | small molecule | Prednisolone | Therapeutic strategy associated | Details |
| R0334 | DB00924 | approved | small molecule | Cyclobenzaprine | Target associated | Details |
| R0341 | DB00940 | approved; investigational | small molecule | Methantheline | Indication associated | Details |
| R0344 | DB00954 | experimental | small molecule | Dirithromycin | Indication associated | Details |
| R0345 | DB00959 | approved; vet_approved | small molecule | Methylprednisolone | Therapeutic strategy associated | Details |
| R0349 | DB00969 | approved; withdrawn | small molecule | Alosetron | Indication associated | Details |
| R0358 | DB00994 | approved; vet_approved | small molecule | Neomycin | Indication associated | Details |
| R0364 | DB01004 | approved; investigational | small molecule | Ganciclovir | Indication associated | Details |
| R0370 | DB01015 | approved | small molecule | Sulfamethoxazole | Indication associated | Details |
| R0385 | DB01050 | approved | small molecule | Ibuprofen | Target associated | Details |
| R0392 | DB01070 | approved | small molecule | Dihydrotachysterol | Indication associated | Details |
| R0394 | DB01079 | approved; investigational; withdrawn | small molecule | Tegaserod | Therapeutic strategy associated | Details |
| R0404 | DB01103 | investigational | small molecule | Quinacrine | Therapeutic strategy associated | Details |
| R0430 | DB01157 | approved; investigational | small molecule | Trimetrexate | Indication associated | Details |
| R0459 | DB01233 | approved; investigational | small molecule | Metoclopramide | Indication associated | Details |
| R0460 | DB01234 | approved; investigational; vet_approved | small molecule | Dexamethasone | Therapeutic strategy associated | Details |
| R0462 | DB01242 | approved; investigational; vet_approved | small molecule | Clomipramine | Indication associated | Details |
| R0469 | DB01255 | approved; investigational | small molecule | Lisdexamfetamine | Indication associated | Details |
| R0476 | DB01278 | approved; investigational | small molecule | Pramlintide | Therapeutic strategy associated | Details |
| R0481 | DB01294 | approved; vet_approved | small molecule | Bismuth subsalicylate | Therapeutic strategy associated | Details |
| R0505 | DB01380 | approved; investigational | small molecule | Cortisone acetate | Therapeutic strategy associated | Details |
| R0520 | DB01419 | approved | small molecule | Antrafenine | Therapeutic strategy associated | Details |
| R0523 | DB01436 | approved; nutraceutical | small molecule | Alfacalcidol | Indication associated | Details |
| R0540 | DB01602 | approved; investigational | small molecule | Bacampicillin | Indication associated | Details |
| R0541 | DB01604 | approved | small molecule | Pivampicillin | Indication associated | Details |
| R0547 | DB01625 | approved; vet_approved | small molecule | Isopropamide | Indication associated | Details |
| R0549 | DB01627 | approved; vet_approved | small molecule | Lincomycin | Indication associated | Details |
| R0622 | DB04838 | approved | small molecule | Cyclandelate | Indication associated | Details |
| R0625 | DB04852 | investigational | small molecule | Implitapide | Indication associated | Details |
| R0628 | DB04856 | investigational | small molecule | Dexloxiglumide | Indication associated | Details |
| R0637 | DB04878 | investigational | small molecule | Voglibose | Indication associated | Details |
| R0639 | DB04885 | investigational | small molecule | Cilansetron | Indication associated | Details |
| R0645 | DB04917 | investigational | small molecule | Renzapride | Indication associated | Details |
| R0649 | DB04924 | investigational | small molecule | Itopride | Therapeutic strategy associated | Details |
| R0655 | DB04936 | investigational | small molecule | Tagatose | Indication associated | Details |
| R0685 | DB05049 | investigational | small molecule | DDP733 | Indication associated | Details |
| R0692 | DB05072 | investigational | small molecule | AV608 | Therapeutic strategy associated | Details |
| R0703 | DB05104 | investigational | small molecule | Asimadoline | Indication associated | Details |
| R0728 | DB05189 | investigational | small molecule | EPC2407 | Therapeutic strategy associated | Details |
| R0732 | DB05199 | investigational | small molecule | LX1031 | Indication associated | Details |
| R0767 | DB05311 | approved; investigational | biotech | Ecallantide | Therapeutic strategy associated | Details |
| R0772 | DB05326 | investigational | small molecule | INKP-102 | Indication associated | Details |
| R0782 | DB05395 | investigational | small molecule | Amibegron | Indication associated | Details |
| R0790 | DB05418 | investigational | small molecule | GW 597599 | Indication associated | Details |
| R0803 | DB05449 | investigational | small molecule | FM-VP4 | Indication associated | Details |
| R0823 | DB05511 | investigational | small molecule | Piclidenoson | Therapeutic strategy associated | Details |
| R0839 | DB05642 | investigational | small molecule | DDP-225 | Indication associated | Details |
| R0840 | DB05645 | investigational | small molecule | Larazotide | Indication associated | Details |
| R0847 | DB05678 | investigational | small molecule | SLx-4090 | Indication associated | Details |
| R0866 | DB05768 | investigational | small molecule | Alkaline Phosphatase | Therapeutic strategy associated | Details |
| R0895 | DB05894 | investigational | small molecule | GT 389-255 | Therapeutic strategy associated | Details |
| R0897 | DB05905 | investigational | small molecule | TD-2749 | Indication associated | Details |
| R0909 | DB05973 | investigational | small molecule | Inosine 5'-sulfate | Indication associated | Details |
| R0933 | DB06154 | approved | small molecule | Pentaerythritol tetranitrate | Therapeutic strategy associated | Details |
| R0947 | DB06224 | investigational | small molecule | Alicaforsen | Therapeutic strategy associated | Details |
| R0982 | DB06326 | investigational | biotech | Latiglutenase | Indication associated | Details |
| R1013 | DB06435 | investigational | small molecule | Tarazepide | Indication associated | Details |
| R1027 | DB06480 | approved | small molecule | Prucalopride | Indication associated | Details |
| R1049 | DB06586 | investigational | small molecule | Cetilistat | Therapeutic strategy associated | Details |
| R1089 | DB06736 | approved; investigational | small molecule | Aceclofenac | Therapeutic strategy associated | Details |
| R1097 | DB06779 | approved | small molecule | Dalteparin | Indication associated | Details |
| R1104 | DB06800 | approved | small molecule | Methylnaltrexone | Indication associated | Details |
| R1107 | DB06824 | approved; investigational | small molecule | Triethylenetetramine | Therapeutic strategy associated | Details |