Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Intestinal161 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1161 | DB08822 | approved; investigational | small molecule | Azilsartan medoxomil | Target associated | Details |
| R1164 | DB08834 | experimental; investigational | small molecule | Tauroursodeoxycholic acid | Indication associated | Details |
| R1170 | DB08862 | approved; investigational | small molecule | Cholecystokinin | Therapeutic strategy associated | Details |
| R1173 | DB08874 | approved | small molecule | Fidaxomicin | Therapeutic strategy associated | Details |
| R1180 | DB08890 | approved | small molecule | Linaclotide | Therapeutic strategy associated | Details |
| R1181 | DB08895 | approved; investigational | small molecule | Tofacitinib | Therapeutic strategy associated | Details |
| R1193 | DB09012 | experimental; withdrawn | small molecule | Carbazochrome | Therapeutic strategy associated | Details |
| R1194 | DB09020 | approved | small molecule | Bisacodyl | Indication associated | Details |
| R1198 | DB09033 | approved | biotech | Vedolizumab | Therapeutic strategy associated | Details |
| R1199 | DB09042 | approved | small molecule | Tedizolid phosphate | Indication associated | Details |
| R1201 | DB09049 | approved | small molecule | Naloxegol | Indication associated | Details |
| R1204 | DB09053 | approved | small molecule | Ibrutinib | Therapeutic strategy associated | Details |
| R1218 | DB09087 | approved | small molecule | Potassium alum | Indication associated | Details |
| R1219 | DB09089 | approved | small molecule | Trimebutine | Indication associated | Details |
| R1220 | DB09090 | approved | small molecule | Pinaverium | Indication associated | Details |
| R1223 | DB09099 | approved; investigational | small molecule | Somatostatin | Therapeutic strategy associated | Details |
| R1225 | DB09104 | approved; investigational | small molecule | Magnesium hydroxide | Therapeutic strategy associated | Details |
| R1244 | DB09213 | approved; investigational | small molecule | Dexibuprofen | Therapeutic strategy associated | Details |
| R1251 | DB09221 | experimental | small molecule | Polaprezinc | Therapeutic strategy associated | Details |
| R1277 | DB09272 | approved; investigational | small molecule | Eluxadoline | Indication associated | Details |
| R1283 | DB09285 | experimental | small molecule | Morniflumate | Therapeutic strategy associated | Details |
| R1284 | DB09287 | approved; vet_approved | small molecule | Polyethylene glycol | Indication associated | Details |
| R1297 | DB09311 | experimental | small molecule | Polycarbophil | Indication associated | Details |
| R1304 | DB09357 | approved | small molecule | Dexpanthenol | Therapeutic strategy associated | Details |
| R1311 | DB09449 | approved | small molecule | Sodium phosphate, monobasic | Indication associated | Details |
| R1316 | DB09532 | approved | biotech | Secretin human | Therapeutic strategy associated | Details |
| R1334 | DB11107 | experimental | small molecule | Potassium bitartrate | Indication associated | Details |
| R1336 | DB11113 | approved; investigational; nutraceutical; vet_approved | biotech | Castor oil | Therapeutic strategy associated | Details |
| R1337 | DB11114 | approved | biotech | Eucalyptus oil | Therapeutic strategy associated | Details |
| R1348 | DB11198 | approved; investigational | biotech | Peppermint oil | Indication associated | Details |
| R1354 | DB11228 | approved | small molecule | Methylcellulose | Indication associated | Details |
| R1393 | DB11700 | approved; investigational | small molecule | Setmelanotide | Therapeutic strategy associated | Details |
| R1397 | DB11735 | approved; investigational | small molecule | Galactose | Indication associated | Details |
| R1402 | DB11761 | approved; investigational | small molecule | Tenapanor | Indication associated | Details |
| R1430 | DB12035 | approved; investigational | small molecule | Sarecycline | Therapeutic strategy associated | Details |
| R1440 | DB12249 | approved; investigational | biotech | Stem bromelain | Therapeutic strategy associated | Details |
| R1442 | DB12328 | approved; investigational | small molecule | Cantharidin | Therapeutic strategy associated | Details |
| R1451 | DB12500 | approved; investigational | small molecule | Fedratinib | Therapeutic strategy associated | Details |
| R1461 | DB12764 | investigational | small molecule | Opaganib | Therapeutic strategy associated | Details |
| R1462 | DB12783 | approved; investigational | small molecule | Benserazide | Therapeutic strategy associated | Details |
| R1468 | DB12942 | approved; investigational | small molecule | Lactitol | Indication associated | Details |
| R1484 | DB13170 | approved; investigational | small molecule | Plecanatide | Therapeutic strategy associated | Details |
| R1493 | DB13749 | approved; investigational | small molecule | Magnesium gluconate | Indication associated | Details |
| R1495 | DB13783 | approved; investigational | small molecule | Acemetacin | Therapeutic strategy associated | Details |
| R1497 | DB13873 | approved | small molecule | Fenofibric acid | Target associated | Details |
| R1505 | DB13949 | approved | small molecule | Ferric cation | Therapeutic strategy associated | Details |
| R1506 | DB13973 | approved; investigational | biotech | Remestemcel-L | Therapeutic strategy associated | Details |
| R1508 | DB14001 | approved; nutraceutical; vet_approved | small molecule | alpha-Tocopherol succinate | Therapeutic strategy associated | Details |
| R1515 | DB14012 | approved; investigational | biotech | Burosumab | Indication associated | Details |
| R1518 | DB14487 | approved; investigational | small molecule | Zinc acetate | Therapeutic strategy associated | Details |
| R1519 | DB14502 | approved | small molecule | Sodium phosphate, dibasic | Indication associated | Details |
| R1520 | DB14503 | approved | small molecule | Sodium phosphate, monobasic, unspecified form | Indication associated | Details |
| R1524 | DB14533 | approved; investigational | small molecule | Zinc chloride | Therapeutic strategy associated | Details |
| R1532 | DB14569 | approved; investigational | small molecule | Tedizolid | Indication associated | Details |
| R1534 | DB14631 | approved; vet_approved | small molecule | Prednisolone phosphate | Therapeutic strategy associated | Details |
| R1537 | DB14669 | approved; vet_approved | small molecule | Betamethasone phosphate | Therapeutic strategy associated | Details |
| R1539 | DB14684 | approved | small molecule | Calcium polycarbophil | Indication associated | Details |
| R1543 | DB14783 | approved; investigational | small molecule | Diroximel fumarate | Therapeutic strategy associated | Details |
| R1561 | DB15444 | approved; investigational | small molecule | Elexacaftor | Therapeutic strategy associated | Details |
| R1565 | DB15566 | approved; vet_approved | small molecule | Prednisolone acetate | Therapeutic strategy associated | Details |
| R1566 | DB15595 | approved | biotech | Ebola Zaire vaccine (live, attenuated) | Therapeutic strategy associated | Details |