Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Bone137 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0006 | DB00016 | approved | biotech | Erythropoietin | Therapeutic strategy associated | Details |
| R0007 | DB00017 | approved; investigational | biotech | Salmon calcitonin | Indication associated | Details |
| R0009 | DB00026 | approved | biotech | Anakinra | Therapeutic strategy associated | Details |
| R0010 | DB00028 | approved; investigational | biotech | Human immunoglobulin G | Indication associated | Details |
| R0027 | DB00091 | approved; investigational; vet_approved | small molecule | Cyclosporine | Therapeutic strategy associated | Details |
| R0046 | DB00138 | approved; nutraceutical | small molecule | Cystine | Therapeutic strategy associated | Details |
| R0048 | DB00141 | approved; investigational; nutraceutical | small molecule | N-Acetylglucosamine | Indication associated | Details |
| R0049 | DB00146 | approved; nutraceutical | small molecule | Calcifediol | Indication associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0058 | DB00170 | approved; nutraceutical | small molecule | Menadione | Therapeutic strategy associated | Details |
| R0104 | DB00282 | approved | small molecule | Pamidronic acid | Therapeutic strategy associated | Details |
| R0105 | DB00286 | approved | small molecule | Conjugated estrogens | Indication associated | Details |
| R0116 | DB00326 | approved | small molecule | Calcium glucoheptonate | Indication associated | Details |
| R0139 | DB00394 | approved; investigational | small molecule | Beclomethasone dipropionate | Therapeutic strategy associated | Details |
| R0141 | DB00399 | approved | small molecule | Zoledronic acid | Therapeutic strategy associated | Details |
| R0146 | DB00438 | approved | small molecule | Ceftazidime | Indication associated | Details |
| R0162 | DB00479 | approved; investigational; vet_approved | small molecule | Amikacin | Indication associated | Details |
| R0164 | DB00481 | approved; investigational | small molecule | Raloxifene | Therapeutic strategy associated | Details |
| R0181 | DB00537 | approved; investigational | small molecule | Ciprofloxacin | Indication associated | Details |
| R0182 | DB00539 | approved; investigational | small molecule | Toremifene | Therapeutic strategy associated | Details |
| R0211 | DB00603 | approved; investigational | small molecule | Medroxyprogesterone acetate | Therapeutic strategy associated | Details |
| R0220 | DB00621 | approved; investigational | small molecule | Oxandrolone | Therapeutic strategy associated | Details |
| R0223 | DB00630 | approved | small molecule | Alendronic acid | Therapeutic strategy associated | Details |
| R0238 | DB00684 | approved; investigational | small molecule | Tobramycin | Indication associated | Details |
| R0249 | DB00710 | approved; investigational | small molecule | Ibandronate | Therapeutic strategy associated | Details |
| R0309 | DB00853 | approved; investigational | small molecule | Temozolomide | Therapeutic strategy associated | Details |
| R0319 | DB00875 | approved; investigational; withdrawn | small molecule | Flupentixol | Indication associated | Details |
| R0324 | DB00884 | approved; investigational | small molecule | Risedronic acid | Therapeutic strategy associated | Details |
| R0352 | DB00977 | approved | small molecule | Ethinylestradiol | Indication associated | Details |
| R0359 | DB00995 | approved; investigational | small molecule | Auranofin | Therapeutic strategy associated | Details |
| R0365 | DB01008 | approved; investigational | small molecule | Busulfan | Therapeutic strategy associated | Details |
| R0367 | DB01012 | approved | small molecule | Cinacalcet | Therapeutic strategy associated | Details |
| R0372 | DB01017 | approved; investigational | small molecule | Minocycline | Target associated | Details |
| R0392 | DB01070 | approved | small molecule | Dihydrotachysterol | Indication associated | Details |
| R0412 | DB01117 | approved | small molecule | Atovaquone | Indication associated | Details |
| R0430 | DB01157 | approved; investigational | small molecule | Trimetrexate | Indication associated | Details |
| R0483 | DB01296 | approved; investigational | small molecule | Glucosamine | Indication associated | Details |
| R0489 | DB01321 | investigational | small molecule | Josamycin | Indication associated | Details |
| R0492 | DB01327 | approved | small molecule | Cefazolin | Indication associated | Details |
| R0493 | DB01328 | approved; investigational | small molecule | Cefonicid | Indication associated | Details |
| R0523 | DB01436 | approved; nutraceutical | small molecule | Alfacalcidol | Indication associated | Details |
| R0537 | DB01597 | approved; investigational | small molecule | Cilastatin | Indication associated | Details |
| R0538 | DB01598 | approved | small molecule | Imipenem | Indication associated | Details |
| R0552 | DB01708 | approved; investigational; nutraceutical | small molecule | Prasterone | Target associated | Details |
| R0559 | DB02187 | experimental | small molecule | Equilin | Indication associated | Details |
| R0608 | DB04570 | approved; investigational | small molecule | Latamoxef | Indication associated | Details |
| R0626 | DB04854 | approved | small molecule | Febuxostat | Therapeutic strategy associated | Details |
| R0642 | DB04900 | investigational | biotech | Thymalfasin | Therapeutic strategy associated | Details |
| R0643 | DB04901 | investigational | biotech | Galiximab | Indication associated | Details |
| R0665 | DB04974 | investigational | small molecule | Rimiducid | Therapeutic strategy associated | Details |
| R0672 | DB04999 | investigational | small molecule | MBO7133 | Therapeutic strategy associated | Details |
| R0681 | DB05035 | investigational | small molecule | Eprotirome | Target associated | Details |
| R0696 | DB05084 | approved; investigational | biotech | Abaloparatide | Indication associated | Details |
| R0752 | DB05244 | investigational | small molecule | G4544 | Indication associated | Details |
| R0753 | DB05255 | investigational | small molecule | Ronacaleret | Indication associated | Details |
| R0755 | DB05260 | approved; investigational | small molecule | Gallium nitrate | Therapeutic strategy associated | Details |
| R0758 | DB05273 | approved; investigational | small molecule | Samarium (153Sm) lexidronam | Indication associated | Details |
| R0760 | DB05295 | investigational | small molecule | Eldecalcitol | Indication associated | Details |
| R0766 | DB05309 | investigational | small molecule | TP-508 | Indication associated | Details |
| R0812 | DB05479 | investigational | small molecule | CZEN 002 | Therapeutic strategy associated | Details |
| R0845 | DB05671 | investigational | biotech | AC-100 | Therapeutic strategy associated | Details |
| R0854 | DB05732 | investigational | small molecule | Strontium malonate | Indication associated | Details |
| R0856 | DB05736 | investigational | small molecule | MIV-701 | Indication associated | Details |
| R0872 | DB05787 | investigational | biotech | LM-609 | Therapeutic strategy associated | Details |
| R0880 | DB05825 | investigational | small molecule | NCX 1015 | Therapeutic strategy associated | Details |
| R0881 | DB05829 | approved; investigational | biotech | Parathyroid hormone | Indication associated | Details |
| R0891 | DB05882 | investigational | small molecule | CHF 4227 | Indication associated | Details |
| R0893 | DB05889 | approved; investigational | biotech | Inotuzumab ozogamicin | Therapeutic strategy associated | Details |
| R0936 | DB06168 | approved; investigational | biotech | Canakinumab | Therapeutic strategy associated | Details |
| R0941 | DB06202 | approved; investigational | small molecule | Lasofoxifene | Indication associated | Details |
| R0953 | DB06244 | investigational | biotech | Trafermin | Indication associated | Details |
| R0957 | DB06249 | approved; investigational | small molecule | Arzoxifene | Indication associated | Details |
| R0960 | DB06255 | experimental | small molecule | Incadronic acid | Therapeutic strategy associated | Details |
| R0973 | DB06285 | approved; investigational | biotech | Teriparatide | Indication associated | Details |
| R0995 | DB06367 | investigational | small molecule | Relacatib | Indication associated | Details |
| R1002 | DB06401 | approved; investigational | small molecule | Bazedoxifene | Indication associated | Details |
| R1035 | DB06511 | investigational | biotech | AMGN-0007 | Target associated | Details |
| R1055 | DB06602 | approved; investigational | biotech | Reslizumab | Therapeutic strategy associated | Details |
| R1063 | DB06612 | approved; investigational | biotech | Mepolizumab | Therapeutic strategy associated | Details |
| R1069 | DB06643 | approved | biotech | Denosumab | Target associated | Details |
| R1075 | DB06670 | investigational | small molecule | Odanacatib | Indication associated | Details |
| R1084 | DB06703 | approved | small molecule | Gadobutrol | Indication associated | Details |
| R1096 | DB06778 | approved | small molecule | Cupric sulfate | Therapeutic strategy associated | Details |
| R1099 | DB06784 | approved | small molecule | Gallium citrate Ga-67 | Therapeutic strategy associated | Details |
| R1158 | DB08818 | approved; vet_approved | small molecule | Hyaluronic acid | Therapeutic strategy associated | Details |
| R1177 | DB08881 | approved | small molecule | Vemurafenib | Therapeutic strategy associated | Details |
| R1204 | DB09053 | approved | small molecule | Ibrutinib | Therapeutic strategy associated | Details |
| R1205 | DB09054 | approved | small molecule | Idelalisib | Therapeutic strategy associated | Details |
| R1211 | DB09070 | approved; investigational | small molecule | Tibolone | Therapeutic strategy associated | Details |
| R1229 | DB09121 | approved; withdrawn | small molecule | Aurothioglucose | Therapeutic strategy associated | Details |
| R1233 | DB09139 | approved | small molecule | Technetium Tc-99m oxidronate | Indication associated | Details |
| R1235 | DB09163 | approved | small molecule | Technetium Tc-99m exametazime | Indication associated | Details |
| R1236 | DB09165 | approved | small molecule | Technetium Tc-99m pyrophosphate | Indication associated | Details |
| R1276 | DB09267 | approved; withdrawn | small molecule | Strontium ranelate | Therapeutic strategy associated | Details |
| R1283 | DB09285 | experimental | small molecule | Morniflumate | Therapeutic strategy associated | Details |
| R1290 | DB09301 | approved; investigational; nutraceutical | small molecule | Chondroitin sulfate | Therapeutic strategy associated | Details |
| R1298 | DB09320 | approved; vet_approved | small molecule | Procaine benzylpenicillin | Indication associated | Details |
| R1307 | DB09398 | approved | small molecule | Fluoride ion F-18 | Indication associated | Details |
| R1308 | DB09409 | approved | small molecule | Magnesium acetate tetrahydrate | Indication associated | Details |
| R1320 | DB09570 | approved; investigational | small molecule | Ixazomib | Therapeutic strategy associated | Details |