Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Cardiovascular137 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0008 | DB00022 | approved | biotech | Peginterferon alfa-2b | Therapeutic strategy associated | Details |
| R0030 | DB00107 | approved; vet_approved | biotech | Oxytocin | Indication associated | Details |
| R0035 | DB00119 | approved; investigational; nutraceutical | small molecule | Pyruvic acid | Indication associated | Details |
| R0038 | DB00125 | investigational; nutraceutical | small molecule | Arginine | Therapeutic strategy associated | Details |
| R0043 | DB00132 | approved; investigational; nutraceutical | small molecule | alpha-Linolenic acid | Therapeutic strategy associated | Details |
| R0055 | DB00157 | approved; nutraceutical | small molecule | NADH | Target associated | Details |
| R0056 | DB00159 | approved; nutraceutical | small molecule | Icosapent | Therapeutic strategy associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0062 | DB00175 | approved | small molecule | Pravastatin | Target associated | Details |
| R0063 | DB00176 | approved; investigational | small molecule | Fluvoxamine | Indication associated | Details |
| R0064 | DB00177 | approved; investigational | small molecule | Valsartan | Therapeutic strategy associated | Details |
| R0065 | DB00178 | approved | small molecule | Ramipril | Therapeutic strategy associated | Details |
| R0068 | DB00182 | approved; illicit; investigational | small molecule | Amphetamine | Indication associated | Details |
| R0071 | DB00193 | approved; investigational | small molecule | Tramadol | Therapeutic strategy associated | Details |
| R0074 | DB00201 | approved | small molecule | Caffeine | Indication associated | Details |
| R0082 | DB00215 | approved | small molecule | Citalopram | Indication associated | Details |
| R0088 | DB00227 | approved; investigational | small molecule | Lovastatin | Therapeutic strategy associated | Details |
| R0098 | DB00264 | approved; investigational | small molecule | Metoprolol | Therapeutic strategy associated | Details |
| R0103 | DB00281 | approved; vet_approved | small molecule | Lidocaine | Therapeutic strategy associated | Details |
| R0105 | DB00286 | approved | small molecule | Conjugated estrogens | Indication associated | Details |
| R0111 | DB00310 | approved | small molecule | Chlorthalidone | Therapeutic strategy associated | Details |
| R0113 | DB00321 | approved | small molecule | Amitriptyline | Indication associated | Details |
| R0117 | DB00328 | approved; investigational | small molecule | Indomethacin | Therapeutic strategy associated | Details |
| R0120 | DB00335 | approved | small molecule | Atenolol | Therapeutic strategy associated | Details |
| R0123 | DB00343 | approved; investigational | small molecule | Diltiazem | Therapeutic strategy associated | Details |
| R0131 | DB00365 | approved; investigational; withdrawn | small molecule | Grepafloxacin | Indication associated | Details |
| R0164 | DB00481 | approved; investigational | small molecule | Raloxifene | Therapeutic strategy associated | Details |
| R0165 | DB00482 | approved; investigational | small molecule | Celecoxib | Therapeutic strategy associated | Details |
| R0166 | DB00484 | approved | small molecule | Brimonidine | Therapeutic strategy associated | Details |
| R0189 | DB00555 | approved; investigational | small molecule | Lamotrigine | Indication associated | Details |
| R0215 | DB00612 | approved | small molecule | Bisoprolol | Indication associated | Details |
| R0227 | DB00641 | approved | small molecule | Simvastatin | Therapeutic strategy associated | Details |
| R0256 | DB00727 | approved; investigational | small molecule | Nitroglycerin | Indication associated | Details |
| R0266 | DB00758 | approved | small molecule | Clopidogrel | Therapeutic strategy associated | Details |
| R0273 | DB00769 | approved | small molecule | Hydrocortamate | Therapeutic strategy associated | Details |
| R0283 | DB00796 | approved | small molecule | Candesartan cilexetil | Target associated | Details |
| R0288 | DB00808 | approved | small molecule | Indapamide | Therapeutic strategy associated | Details |
| R0291 | DB00814 | approved; vet_approved | small molecule | Meloxicam | Therapeutic strategy associated | Details |
| R0319 | DB00875 | approved; investigational; withdrawn | small molecule | Flupentixol | Indication associated | Details |
| R0320 | DB00876 | approved | small molecule | Eprosartan | Target associated | Details |
| R0331 | DB00914 | approved; investigational; withdrawn | small molecule | Phenformin | Indication associated | Details |
| R0371 | DB01016 | approved | small molecule | Glyburide | Indication associated | Details |
| R0391 | DB01067 | approved; investigational | small molecule | Glipizide | Therapeutic strategy associated | Details |
| R0394 | DB01079 | approved; investigational; withdrawn | small molecule | Tegaserod | Therapeutic strategy associated | Details |
| R0400 | DB01093 | approved; vet_approved | small molecule | Dimethyl sulfoxide | Therapeutic strategy associated | Details |
| R0402 | DB01095 | approved | small molecule | Fluvastatin | Target associated | Details |
| R0405 | DB01104 | approved | small molecule | Sertraline | Indication associated | Details |
| R0425 | DB01149 | approved; withdrawn | small molecule | Nefazodone | Indication associated | Details |
| R0439 | DB01191 | approved; illicit; investigational; withdrawn | small molecule | Dexfenfluramine | Therapeutic strategy associated | Details |
| R0449 | DB01210 | approved | small molecule | Levobunolol | Indication associated | Details |
| R0452 | DB01221 | approved; vet_approved | small molecule | Ketamine | Indication associated | Details |
| R0469 | DB01255 | approved; investigational | small molecule | Lisdexamfetamine | Indication associated | Details |
| R0504 | DB01377 | approved | small molecule | Magnesium oxide | Therapeutic strategy associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0508 | DB01384 | experimental | small molecule | Paramethasone | Therapeutic strategy associated | Details |
| R0512 | DB01395 | approved | small molecule | Drospirenone | Indication associated | Details |
| R0527 | DB01550 | experimental; illicit; withdrawn | small molecule | Fenproporex | Indication associated | Details |
| R0626 | DB04854 | approved | small molecule | Febuxostat | Therapeutic strategy associated | Details |
| R0656 | DB04944 | investigational | small molecule | Acadesine | Therapeutic strategy associated | Details |
| R0689 | DB05061 | investigational | small molecule | GFT14 | Indication associated | Details |
| R0698 | DB05093 | investigational | small molecule | AX200 | Indication associated | Details |
| R0706 | DB05119 | investigational | small molecule | Rilapladib | Indication associated | Details |
| R0719 | DB05157 | investigational | small molecule | KC706 | Therapeutic strategy associated | Details |
| R0733 | DB05201 | investigational | small molecule | V24343 | Therapeutic strategy associated | Details |
| R0777 | DB05367 | investigational | small molecule | Actelion-1 | Indication associated | Details |
| R0789 | DB05416 | investigational | small molecule | Cardarine | Target associated | Details |
| R0831 | DB05549 | investigational | small molecule | INO-1001 | Indication associated | Details |
| R0838 | DB05631 | investigational | small molecule | ALT-2074 | Indication associated | Details |
| R0857 | DB05737 | investigational | small molecule | Varespladib methyl | Indication associated | Details |
| R0867 | DB05769 | investigational | small molecule | LCP-AtorFen | Indication associated | Details |
| R0875 | DB05804 | investigational | small molecule | Prasterone sulfate | Therapeutic strategy associated | Details |
| R0884 | DB05843 | investigational | small molecule | trans NV-04 | Indication associated | Details |
| R0899 | DB05911 | investigational | small molecule | RUS 3108 | Indication associated | Details |
| R0933 | DB06154 | approved | small molecule | Pentaerythritol tetranitrate | Therapeutic strategy associated | Details |
| R0944 | DB06207 | approved | small molecule | Silodosin | Therapeutic strategy associated | Details |
| R0949 | DB06228 | approved | small molecule | Rivaroxaban | Indication associated | Details |
| R0951 | DB06237 | approved | small molecule | Avanafil | Therapeutic strategy associated | Details |
| R0967 | DB06270 | investigational | small molecule | MAHDL01 | Indication associated | Details |
| R0978 | DB06311 | investigational | small molecule | Darapladib | Therapeutic strategy associated | Details |
| R0990 | DB06350 | investigational | small molecule | Elinogrel | Indication associated | Details |
| R0997 | DB06376 | investigational | small molecule | CHGN111 | Therapeutic strategy associated | Details |
| R1018 | DB06448 | approved; investigational | small molecule | Lonafarnib | Therapeutic strategy associated | Details |
| R1027 | DB06480 | approved | small molecule | Prucalopride | Indication associated | Details |
| R1060 | DB06609 | investigational | small molecule | Odiparcil | Indication associated | Details |
| R1082 | DB06693 | experimental | small molecule | Mevastatin | Target associated | Details |
| R1157 | DB08816 | approved | small molecule | Ticagrelor | Therapeutic strategy associated | Details |
| R1161 | DB08822 | approved; investigational | small molecule | Azilsartan medoxomil | Target associated | Details |
| R1167 | DB08838 | experimental | small molecule | Agmatine | Therapeutic strategy associated | Details |
| R1168 | DB08842 | approved; investigational | small molecule | Acetylcarnitine | Therapeutic strategy associated | Details |
| R1187 | DB08915 | investigational | small molecule | Aleglitazar | Target associated | Details |
| R1190 | DB08949 | approved; withdrawn | small molecule | Inositol nicotinate | Therapeutic strategy associated | Details |
| R1195 | DB09026 | approved; investigational | small molecule | Aliskiren | Indication associated | Details |
| R1196 | DB09030 | approved | small molecule | Vorapaxar | Therapeutic strategy associated | Details |
| R1211 | DB09070 | approved; investigational | small molecule | Tibolone | Therapeutic strategy associated | Details |
| R1232 | DB09134 | approved | small molecule | Ioversol | Indication associated | Details |
| R1234 | DB09140 | approved; vet_approved | small molecule | Oxygen | Therapeutic strategy associated | Details |
| R1239 | DB09194 | withdrawn | small molecule | Etoperidone | Indication associated | Details |
| R1252 | DB09227 | experimental | small molecule | Barnidipine | Therapeutic strategy associated | Details |
| R1255 | DB09231 | experimental | small molecule | Benidipine | Indication associated | Details |
| R1257 | DB09235 | experimental | small molecule | Efonidipine | Therapeutic strategy associated | Details |