Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
Article ID | PMID | Source | Title | Publish Year | |
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A24325 | 22997912 | Ter Arkh | [Clinicopathogenetic characteristics of cardiorenal syndrome in non-alcoholic fatty liver disease]. | 2012 | Details |
A24326 | 22997724 | Klin Med (Mosk) | [Pathogenetic therapy of metabolic syndrome at the stage of visceral lesions]. | 2012 | Details |
A24342 | 22983378 | J Pediatr Gastroenterol Nutr | Serum retinol-binding protein 4 is independently associated with pediatric NAFLD and fasting triglyceride level. | 2013 | Details |
A24345 | 22981383 | Biochem Pharmacol | Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. | 2012 | Details |
A24351 | 22977624 | Exp Ther Med | Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP and L-FABP in non-alcoholic fatty liver disease. | 2011 | Details |
A24352 | 22975640 | Clin Biochem | Combinative analysis of factors influence serum alanine aminotransferase activity in adult male population from southern China. | 2012 | Details |
A24353 | 22974598 | J Pediatr Surg | Patterns of surgical weight loss and resolution of metabolic abnormalities in superobese bariatric adolescents. | 2012 | Details |
A24359 | 22969777 | Cardiorenal Med | Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy. | 2012 | Details |
A24360 | 22969728 | Front Physiol | A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells. | 2012 | Details |
A24363 | 22966224 | PPAR Res | Update on pparγ and nonalcoholic Fatty liver disease. | 2012 | Details |
A24364 | 22965160 | Horm Res Paediatr | Consequences of stopping and restarting leptin in an adolescent with lipodystrophy. | 2012 | Details |
A24367 | 22964692 | Clin Ter | [Relation of non-alcoholic hepatic steatosis to early carotid atherosclerosis in diet-controlled impaired glucose tolerance subjects]. | 2012 | Details |
A24368 | 22964626 | Digestion | High prevalence of gastroesophageal reflux symptoms in patients with non-alcoholic fatty liver disease associated with serum levels of triglyceride and cholesterol but not simple visceral obesity. | 2012 | Details |
A24372 | 22962039 | Pediatr Obes | Analysis of adipokine concentrations in paediatric non-alcoholic fatty liver disease. | 2012 | Details |
A24374 | 22960889 | Indian J Med Res | Association of pro-inflammatory cytokines, adipokines & oxidative stress with insulin resistance & non-alcoholic fatty liver disease. | 2012 | Details |
A24375 | 22960565 | J Proteomics | Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin. | 2012 | Details |
A24376 | 22959976 | Arch Med Res | Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population. | 2012 | Details |
A24378 | 22958053 | Aliment Pharmacol Ther | Non-alcoholic fatty liver disease (NAFLD) is associated with low level of physical activity: a population-based study. | 2012 | Details |
A24379 | 22955994 | Diabetologia | Protection from non-alcoholic steatohepatitis and liver tumourigenesis in high fat-fed insulin receptor substrate-1-knockout mice despite insulin resistance. | 2012 | Details |
A24383 | 22952059 | Mol Med | Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response. | 2012 | Details |
A24385 | 22950627 | Scand J Clin Lab Invest | A novel appetite peptide, nesfatin-1 in patients with non-alcoholic fatty liver disease. | 2012 | Details |
A24386 | 22950055 | Diabetes Metab J | GLP-1 Receptor Agonist and Non-Alcoholic Fatty Liver Disease. | 2012 | Details |
A24387 | 22949894 | Case Rep Gastroenterol | Dipeptidyl Peptidase IV Inhibitor Improves Insulin Resistance and Steatosis in a Refractory Nonalcoholic Fatty Liver Disease Patient: A Case Report. | 2012 | Details |
A24390 | 22941955 | Hepatology | Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model. | 2013 | Details |
A24393 | 22940046 | J Hepatol | CYP2E1 and oxidant stress in alcoholic and non-alcoholic fatty liver disease. | 2012 | Details |
A24394 | 22940028 | Phytomedicine | Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells. | 2012 | Details |
A24401 | 22934096 | Front Immunol | Resolution of inflammation in obesity-induced liver disease. | 2012 | Details |
A24402 | 22934006 | Front Physiol | Liver fibrogenesis in non-alcoholic steatohepatitis. | 2012 | Details |
A24403 | 22933860 | Gastroenterol Hepatol (N Y) | Hepatitis C virus infection and nonalcoholic steatohepatitis. | 2012 | Details |
A24405 | 22932913 | Horm Metab Res | Reversion of steatosis by SREBP-1c antisense oligonucleotide did not improve hepatic insulin action in diet-induced obesity mice. | 2012 | Details |
A24406 | 22932160 | Eur J Gastroenterol Hepatol | Long-term effects of aerobic plus resistance training on the adipokines and neuropeptides in nonalcoholic fatty liver disease obese adolescents. | 2012 | Details |
A24422 | 22913901 | Postgrad Med | Managing diabetes in patients with chronic liver disease. | 2012 | Details |
A24424 | 22912545 | World J Gastroenterol | Overview and developments in noninvasive diagnosis of nonalcoholic fatty liver disease. | 2012 | Details |
A24429 | 22903613 | Endocrinology | Hepatic insulin signaling changes: possible mechanism in prenatal hypoxia-increased susceptibility of fatty liver in adulthood. | 2012 | Details |
A24431 | 22902548 | J Hepatol | Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model. | 2012 | Details |
A24434 | 22899407 | Georgian Med News | [Treatment of nonalcogolic fatty disease of liver]. | 2012 | Details |
A24435 | 22899406 | Georgian Med News | [Peculiarities of metabolic syndrome and nonalcogolic fatty liver disease in menopausal women]. | 2012 | Details |
A24438 | 22893453 | Endocr J | Fatty liver as a consequence and cause of insulin resistance: lessons from type 2 diabetic liver. | 2012 | Details |
A24439 | 22892494 | Intern Med | Long-term branched-chain amino acid supplementation improves glucose tolerance in patients with nonalcoholic steatohepatitis-related cirrhosis. | 2012 | Details |
A24452 | 22878918 | Dig Dis Sci | Probucol ameliorates the development of nonalcoholic steatohepatitis in rats fed high-fat diets. | 2012 | Details |
A24455 | 22876924 | Curr Med Chem | Adiponectin: key player in the adipose tissue-liver crosstalk. | 2012 | Details |
A24458 | 22876038 | World J Gastroenterol | Moro orange juice prevents fatty liver in mice. | 2012 | Details |
A24459 | 22876027 | World J Gastroenterol | Diagnostic and therapeutic implications of the association between ferritin level and severity of nonalcoholic fatty liver disease. | 2012 | Details |
A24460 | 22876026 | World J Gastroenterol | Alanine and aspartate aminotransferase and glutamine-cycling pathway: their roles in pathogenesis of metabolic syndrome. | 2012 | Details |
A24461 | 22875138 | Pediatr Cardiol | The relationship between pediatric nonalcoholic fatty liver disease and cardiovascular risk factors and increased risk of atherosclerosis in obese children. | 2012 | Details |
A24469 | 22864348 | Yakugaku Zasshi | [Retinoids as promising treatment for non-alcoholic fatty liver disease]. | 2012 | Details |
A24472 | 22863080 | Liver Int | α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats. | 2012 | Details |
A24476 | 22855698 | World J Hepatol | Lifestyle intervention in non-alcoholic fatty liver disease in Chengyang District, Qingdao, China. | 2012 | Details |
A24477 | 22855696 | World J Hepatol | Life style modification improves insulin resistance and liver histology in patients with non-alcoholic fatty liver disease. | 2012 | Details |
A24479 | 22854109 | Metabolism | High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice. | 2012 | Details |
A24483 | 22849970 | Br J Nutr | Beneficial effect of a weight-stable, low-fat/low-saturated fat/low-glycaemic index diet to reduce liver fat in older subjects. | 2012 | Details |
A24484 | 22848440 | PLoS One | Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease. | 2012 | Details |
A24498 | 22837189 | J Clin Endocrinol Metab | Polycystic ovary syndrome with hyperandrogenism is characterized by an increased risk of hepatic steatosis compared to nonhyperandrogenic PCOS phenotypes and healthy controls, independent of obesity and insulin resistance. | 2012 | Details |
A24500 | 22829522 | Diabetes Care | Fatty liver, insulin resistance, and features of metabolic syndrome: relationships with coronary artery calcium in 10,153 people. | 2012 | Details |
A24501 | 22829450 | Diabetes | Skeletal muscle insulin resistance promotes increased hepatic de novo lipogenesis, hyperlipidemia, and hepatic steatosis in the elderly. | 2012 | Details |
A24507 | 22824483 | Clin Liver Dis | The cardiovascular link to nonalcoholic fatty liver disease: a critical analysis. | 2012 | Details |
A24508 | 22824482 | Clin Liver Dis | Is nonalcoholic fatty liver disease in children the same disease as in adults? | 2012 | Details |
A24511 | 22824479 | Clin Liver Dis | A myriad of pathways to NASH. | 2012 | Details |
A24524 | 22809960 | Dig Liver Dis | Increased insulinogenic index is an independent determinant of nonalcoholic fatty liver disease activity score in patients with normal glucose tolerance. | 2012 | Details |
A24527 | 22807031 | Diabetes | Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. | 2012 | Details |
A24532 | 22796347 | Nutr Metab Cardiovasc Dis | Ambulatory arterial stiffness indices and non-alcoholic fatty liver disease in essential hypertension. | 2012 | Details |
A24535 | 22795319 | Clin Res Hepatol Gastroenterol | Does fructose consumption contribute to non-alcoholic fatty liver disease? | 2012 | Details |
A24536 | 22792295 | PLoS One | The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation. | 2012 | Details |
A24539 | 22789032 | Clin Endocrinol (Oxf) | Fatty liver and insulin resistance in children with hypobetalipoproteinemia: the importance of aetiology. | 2013 | Details |
A24540 | 22788090 | Rom J Intern Med | Non-alcoholic fatty liver disease and the statins treatment. | 2012 | Details |
A24543 | 22770622 | Expert Opin Pharmacother | The safety and effectiveness of statins as treatment for HIV-dyslipidemia: the evidence so far and the future challenges. | 2012 | Details |
A24548 | 22768070 | PLoS One | Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice. | 2012 | Details |
A24553 | 22753171 | Hepatology | Elovl6 promotes nonalcoholic steatohepatitis. | 2012 | Details |
A24557 | 22751691 | Diabetes | Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. | 2012 | Details |
A24562 | 22749135 | J Nutr Biochem | The role of dietary fatty acids in the pathology of metabolic syndrome. | 2012 | Details |
A24563 | 22748277 | Atherosclerosis | Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in Asian Indians. | 2012 | Details |
A24567 | 22742899 | Eur J Pharmacol | Carbenoxolone prevents the development of fatty liver in C57BL/6-Lep ob/ob mice via the inhibition of sterol regulatory element binding protein-1c activity and apoptosis. | 2012 | Details |
A24568 | 22741595 | J Gastroenterol Hepatol | Prevalence and risk factors for non-alcoholic fatty liver disease in Asian people who are not obese. | 2012 | Details |
A24572 | 22738690 | J Cardiol | The association between impaired collateral circulation and non-alcoholic fatty liver in patients with severe coronary artery disease. | 2012 | Details |
A24575 | 22735605 | Eur J Gastroenterol Hepatol | How adiponectin, leptin, and ghrelin orchestrate together and correlate with the severity of nonalcoholic fatty liver disease. | 2012 | Details |
A24576 | 22735219 | Rev Assoc Med Bras (1992) | Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals. | 2013 | Details |
A24577 | 22734967 | Clin Sci (Lond) | Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. | 2012 | Details |
A24579 | 22730920 | Aliment Pharmacol Ther | Review article: non-alcoholic fatty liver disease and osteoporosis--clinical and molecular crosstalk. | 2012 | Details |
A24585 | 22722431 | Dig Dis | Nonalcoholic fatty liver disease/steatohepatitis: epidemiology, pathogenesis, clinical presentation and treatment. | 2012 | Details |
A24586 | 22720311 | J Gastrointestin Liver Dis | Is visceral fat reduction necessary to favour metabolic changes in the liver? | 2012 | Details |
A24591 | 22717644 | Endocrinol Nutr | [Non-alcoholic fatty liver disease and its association with clinical and biochemical variables in obese children and adolescents: effect of a one-year intervention on lifestyle]. | 2012 | Details |
A24592 | 22717200 | J Acad Nutr Diet | The role of diet and nutrient composition in nonalcoholic Fatty liver disease. | 2012 | Details |
A24597 | 22710359 | Int J Mol Med | Silymarin suppresses hepatic stellate cell activation in a dietary rat model of non-alcoholic steatohepatitis: analysis of isolated hepatic stellate cells. | 2012 | Details |
A24600 | 22706738 | Turk J Gastroenterol | Effects of probiotics on methionine choline deficient diet-induced steatohepatitis in rats. | 2012 | Details |
A24604 | 22700629 | Ann Hepatol |  Correlation of adipose tissue with liver histology in Asian Indian patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
A24610 | 22692588 | Int J Mol Med | Curcumin ameliorates mitochondrial dysfunction associated with inhibition of gluconeogenesis in free fatty acid-mediated hepatic lipoapoptosis. | 2012 | Details |
A24612 | 22691891 | Minerva Endocrinol | Is NAFLD an independent risk factor for increased IMT in T2DM? | 2012 | Details |
A24613 | 22691278 | BMC Gastroenterol | A low level of serum total testosterone is independently associated with nonalcoholic fatty liver disease. | 2012 | Details |
A24619 | 22684858 | Hepatology | Nonalcoholic steatohepatitis versus steatosis: adipose tissue insulin resistance and dysfunctional response to fat ingestion predict liver injury and altered glucose and lipoprotein metabolism. | 2012 | Details |
A24620 | 22684314 | Acta Diabetol | Nonalcoholic fatty liver and metabolic syndrome in Italy: results from a multicentric study of the Italian Arteriosclerosis society. | 2012 | Details |
A24626 | 22676641 | Clin Endocrinol (Oxf) | Plasma fetuin-A is associated with endothelial dysfunction and subclinical atherosclerosis in subjects with nonalcoholic fatty liver disease. | 2013 | Details |
A24627 | 22676459 | Cardiovasc Diabetol | Relation between augmentation index and adiponectin during one-year metformin treatment for nonalcoholic steatohepatosis: effects beyond glucose lowering? | 2012 | Details |
A24629 | 22673924 | Int J Vitam Nutr Res | Therapeutic effect of metformin and vitamin E versus prescriptive diet in obese adolescents with fatty liver. | 2011 | Details |
A24630 | 22673296 | Endocr J | A case of glycogenic hepatopathy developed in a patient with new-onset fulminant type 1 diabetes: the role of image modalities in diagnosing hepatic glycogen deposition including gradient-dual-echo MRI. | 2012 | Details |
A24633 | 22672485 | J Am Acad Nurse Pract | Nonalcoholic fatty liver disease: the hepatic metabolic syndrome. | 2012 | Details |
A24634 | 22672330 | Diabet Med | Dorothy Hodgkin Lecture 2012: non-alcoholic fatty liver disease, insulin resistance and ectopic fat: a new problem in diabetes management. | 2012 | Details |
A24636 | 22668875 | Eur J Gastroenterol Hepatol | Metabolic syndrome and nonalcoholic fatty liver disease in a Spanish population: influence of the diagnostic criteria used. | 2012 | Details |
A24637 | 22668639 | J Hepatol | Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis. | 2012 | Details |
A24640 | 22661277 | Endocrine | Assessment of endothelial function in patients with nonalcoholic fatty liver disease. | 2012 | Details |
A24653 | 22646469 | Platelets | Mean platelet volume in biopsy-proven non-alcoholic fatty liver disease. | 2012 | Details |