Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0301 | DB00836 | approved | small molecule | Loperamide | Therapeutic strategy associated | Details |
| R0302 | DB00838 | approved | small molecule | Clocortolone | Therapeutic strategy associated | Details |
| R0303 | DB00839 | approved; investigational | small molecule | Tolazamide | Indication associated | Details |
| R0304 | DB00841 | approved | small molecule | Dobutamine | Therapeutic strategy associated | Details |
| R0305 | DB00843 | approved | small molecule | Donepezil | Therapeutic strategy associated | Details |
| R0306 | DB00845 | approved; investigational | small molecule | Clofazimine | Therapeutic strategy associated | Details |
| R0307 | DB00846 | approved | small molecule | Flurandrenolide | Therapeutic strategy associated | Details |
| R0308 | DB00852 | approved | small molecule | Pseudoephedrine | Target associated | Details |
| R0309 | DB00853 | approved; investigational | small molecule | Temozolomide | Therapeutic strategy associated | Details |
| R0310 | DB00859 | approved | small molecule | Penicillamine | Indication associated | Details |
| R0311 | DB00860 | approved; vet_approved | small molecule | Prednisolone | Therapeutic strategy associated | Details |
| R0312 | DB00861 | approved; investigational | small molecule | Diflunisal | Therapeutic strategy associated | Details |
| R0313 | DB00865 | approved; illicit | small molecule | Benzphetamine | Therapeutic strategy associated | Details |
| R0314 | DB00866 | experimental; withdrawn | small molecule | Alprenolol | Indication associated | Details |
| R0315 | DB00869 | approved | small molecule | Dorzolamide | Indication associated | Details |
| R0316 | DB00870 | approved; withdrawn | small molecule | Suprofen | Therapeutic strategy associated | Details |
| R0317 | DB00872 | approved; investigational | small molecule | Conivaptan | Indication associated | Details |
| R0318 | DB14596 | approved | small molecule | Loteprednol etabonate | Therapeutic strategy associated | Details |
| R0319 | DB00875 | approved; investigational; withdrawn | small molecule | Flupentixol | Indication associated | Details |
| R0320 | DB00876 | approved | small molecule | Eprosartan | Target associated | Details |
| R0321 | DB00880 | approved; vet_approved | small molecule | Chlorothiazide | Therapeutic strategy associated | Details |
| R0322 | DB00881 | approved; investigational | small molecule | Quinapril | Indication associated | Details |
| R0323 | DB00883 | approved; investigational | small molecule | Isosorbide dinitrate | Indication associated | Details |
| R0324 | DB00884 | approved; investigational | small molecule | Risedronic acid | Therapeutic strategy associated | Details |
| R0325 | DB00885 | approved; investigational | small molecule | Pemirolast | Therapeutic strategy associated | Details |
| R0326 | DB00886 | investigational | small molecule | Omapatrilat | Indication associated | Details |
| R0327 | DB00896 | approved | small molecule | Rimexolone | Therapeutic strategy associated | Details |
| R0328 | DB00903 | approved; investigational | small molecule | Etacrynic acid | Therapeutic strategy associated | Details |
| R0329 | DB00905 | approved; investigational | small molecule | Bimatoprost | Indication associated | Details |
| R0330 | DB00912 | approved; investigational | small molecule | Repaglinide | Target associated | Details |
| R0331 | DB00914 | approved; investigational; withdrawn | small molecule | Phenformin | Indication associated | Details |
| R0332 | DB00920 | approved | small molecule | Ketotifen | Therapeutic strategy associated | Details |
| R0333 | DB00922 | approved; investigational | small molecule | Levosimendan | Indication associated | Details |
| R0334 | DB00924 | approved | small molecule | Cyclobenzaprine | Target associated | Details |
| R0335 | DB00925 | approved | small molecule | Phenoxybenzamine | Indication associated | Details |
| R0336 | DB00929 | approved | small molecule | Misoprostol | Indication associated | Details |
| R0337 | DB00934 | approved; investigational | small molecule | Maprotiline | Indication associated | Details |
| R0338 | DB00936 | approved; investigational; vet_approved | small molecule | Salicylic acid | Therapeutic strategy associated | Details |
| R0339 | DB00937 | approved; illicit | small molecule | Diethylpropion | Indication associated | Details |
| R0340 | DB00939 | approved; vet_approved | small molecule | Meclofenamic acid | Therapeutic strategy associated | Details |
| R0341 | DB00940 | approved; investigational | small molecule | Methantheline | Indication associated | Details |
| R0342 | DB00946 | approved; investigational | small molecule | Phenprocoumon | Indication associated | Details |
| R0343 | DB00950 | approved; investigational | small molecule | Fexofenadine | Therapeutic strategy associated | Details |
| R0344 | DB00954 | experimental | small molecule | Dirithromycin | Indication associated | Details |
| R0345 | DB00959 | approved; vet_approved | small molecule | Methylprednisolone | Therapeutic strategy associated | Details |
| R0346 | DB00960 | approved; investigational | small molecule | Pindolol | Indication associated | Details |
| R0347 | DB00963 | approved | small molecule | Bromfenac | Therapeutic strategy associated | Details |
| R0348 | DB00968 | approved | small molecule | Methyldopa | Therapeutic strategy associated | Details |
| R0349 | DB00969 | approved; withdrawn | small molecule | Alosetron | Indication associated | Details |
| R0350 | DB00975 | approved | small molecule | Dipyridamole | Therapeutic strategy associated | Details |
| R0351 | DB00976 | approved | small molecule | Telithromycin | Indication associated | Details |
| R0352 | DB00977 | approved | small molecule | Ethinylestradiol | Indication associated | Details |
| R0353 | DB00978 | approved; investigational | small molecule | Lomefloxacin | Indication associated | Details |
| R0354 | DB00982 | approved | small molecule | Isotretinoin | Therapeutic strategy associated | Details |
| R0355 | DB00988 | approved | small molecule | Dopamine | Indication associated | Details |
| R0356 | DB00991 | approved | small molecule | Oxaprozin | Therapeutic strategy associated | Details |
| R0357 | DB00993 | approved | small molecule | Azathioprine | Therapeutic strategy associated | Details |
| R0358 | DB00994 | approved; vet_approved | small molecule | Neomycin | Indication associated | Details |
| R0359 | DB00995 | approved; investigational | small molecule | Auranofin | Therapeutic strategy associated | Details |
| R0360 | DB00996 | approved; investigational | small molecule | Gabapentin | Indication associated | Details |
| R0361 | DB00999 | approved; vet_approved | small molecule | Hydrochlorothiazide | Indication associated | Details |
| R0362 | DB01000 | approved | small molecule | Cyclacillin | Indication associated | Details |
| R0363 | DB01003 | approved | small molecule | Cromoglicic acid | Therapeutic strategy associated | Details |
| R0364 | DB01004 | approved; investigational | small molecule | Ganciclovir | Indication associated | Details |
| R0365 | DB01008 | approved; investigational | small molecule | Busulfan | Therapeutic strategy associated | Details |
| R0366 | DB01009 | approved; vet_approved | small molecule | Ketoprofen | Therapeutic strategy associated | Details |
| R0367 | DB01012 | approved | small molecule | Cinacalcet | Therapeutic strategy associated | Details |
| R0368 | DB01013 | approved | small molecule | Clobetasol propionate | Therapeutic strategy associated | Details |
| R0369 | DB01014 | approved; investigational | small molecule | Balsalazide | Therapeutic strategy associated | Details |
| R0370 | DB01015 | approved | small molecule | Sulfamethoxazole | Indication associated | Details |
| R0371 | DB01016 | approved | small molecule | Glyburide | Indication associated | Details |
| R0372 | DB01017 | approved; investigational | small molecule | Minocycline | Target associated | Details |
| R0373 | DB01020 | approved | small molecule | Isosorbide mononitrate | Indication associated | Details |
| R0374 | DB01021 | approved; vet_approved | small molecule | Trichlormethiazide | Therapeutic strategy associated | Details |
| R0375 | DB01023 | approved; investigational | small molecule | Felodipine | Indication associated | Details |
| R0376 | DB01024 | approved | small molecule | Mycophenolic acid | Therapeutic strategy associated | Details |
| R0377 | DB01029 | approved; investigational | small molecule | Irbesartan | Target associated | Details |
| R0378 | DB01030 | approved; investigational | small molecule | Topotecan | Therapeutic strategy associated | Details |
| R0379 | DB01032 | approved; investigational | small molecule | Probenecid | Therapeutic strategy associated | Details |
| R0380 | DB01034 | experimental | small molecule | Cerulenin | Therapeutic strategy associated | Details |
| R0381 | DB01037 | approved; investigational; vet_approved | small molecule | Selegiline | Indication associated | Details |
| R0382 | DB01041 | approved; investigational; withdrawn | small molecule | Thalidomide | Target associated | Details |
| R0383 | DB01044 | approved; investigational | small molecule | Gatifloxacin | Indication associated | Details |
| R0384 | DB01047 | approved; investigational | small molecule | Fluocinonide | Therapeutic strategy associated | Details |
| R0385 | DB01050 | approved | small molecule | Ibuprofen | Target associated | Details |
| R0386 | DB01053 | approved; vet_approved | small molecule | Benzylpenicillin | Indication associated | Details |
| R0387 | DB01054 | approved; investigational | small molecule | Nitrendipine | Indication associated | Details |
| R0388 | DB01055 | experimental | small molecule | Mimosine | Therapeutic strategy associated | Details |
| R0389 | DB01064 | approved; investigational | small molecule | Isoprenaline | Therapeutic strategy associated | Details |
| R0390 | DB01066 | approved; investigational | small molecule | Cefditoren | Indication associated | Details |
| R0391 | DB01067 | approved; investigational | small molecule | Glipizide | Therapeutic strategy associated | Details |
| R0392 | DB01070 | approved | small molecule | Dihydrotachysterol | Indication associated | Details |
| R0393 | DB01074 | approved; investigational | small molecule | Perhexiline | Indication associated | Details |
| R0394 | DB01079 | approved; investigational; withdrawn | small molecule | Tegaserod | Therapeutic strategy associated | Details |
| R0395 | DB01082 | approved; vet_approved | small molecule | Streptomycin | Indication associated | Details |
| R0396 | DB01088 | approved; investigational | small molecule | Iloprost | Therapeutic strategy associated | Details |
| R0397 | DB01089 | approved | small molecule | Deserpidine | Therapeutic strategy associated | Details |
| R0398 | DB01090 | approved | small molecule | Pentolinium | Therapeutic strategy associated | Details |
| R0399 | DB01092 | approved | small molecule | Ouabain | Indication associated | Details |
| R0400 | DB01093 | approved; vet_approved | small molecule | Dimethyl sulfoxide | Therapeutic strategy associated | Details |