Investigational Drugs
Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.
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581 records.
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D353 | Sulfonylurea | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D354 | Sulforaphane | Chemical drug | DB12422 | -- | Anticarcinogenic, Antineoplastic, Antioxidant | Under clinical trials | Details |
| D355 | Sumac | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D356 | Symbiotic | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D357 | Synbiotic | Supplement | -- | -- | -- | Under clinical trials | Details |
| D358 | TAF | Chemical drug | DB09299 | -- | -- | Under clinical trials | Details |
| D359 | Taraxacum officinale extract | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D360 | Telmisartan | Chemical drug | DB00966 | PPARG partial agonist | Improve insulin resistance | Under clinical trials | Details |
| D361 | Teneligliptin | Chemical drug | DB11950 | DPP4 inhibitor | -- | Under clinical trials | Details |
| D362 | TERN-101 | Chemical drug | DB16045 | FXR agonist | Enhance lipid metabolism | Under clinical trials | Details |
| D363 | Tesamorelin | Chemical drug | DB08869 | GHRHR agonist;GHRHR binder | Growth stimulant | Under clinical trials | Details |
| D364 | Testosterone Undecanoate | Chemical drug | DB13946 | AR agonist | Hormone replacement drug | Under clinical trials | Details |
| D365 | TEV-45478 | Biological drug | -- | -- | -- | Under clinical trials | Details |
| D366 | Thiazolidinediones | Chemical drug | DB11898 | -- | -- | Under clinical trials | Details |
| D367 | Thioctic acid | Chemical drug | DB00166 | -- | Vitamin source drug | Under clinical trials | Details |
| D368 | Thriphala choorna | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D369 | Thyme | Biological drug | DB10983 | -- | Antibiotic drug, antifungal drug | Under clinical trials | Details |
| D370 | Tirzepatide | Biological drug | DB15171 | GIP agonist; GLP-1 receptor agonist | Improve insulin resistance | Under clinical trials | Details |
| D371 | Tocotrienol | Chemical drug | DB12647 | HMG-CoA inhibitor | Enhance lipid metabolism | Under clinical trials | Details |
| D372 | Tofogliflozin | Chemical drug | DB11824 | SGLT2 inhibitor | Improve insulin resistance | Under clinical trials | Details |
| D373 | Tranilast | Chemical drug | DB07615 | HPGDS inhibitor | -- | Under clinical trials | Details |
| D374 | Trehalose | Chemical drug | DB12310 | -- | -- | Under clinical trials | Details |
| D375 | Trikatu Kajjali Tablet | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D376 | Trimada Kajjali Tablet | Traditional medicine | -- | -- | -- | Under clinical trials | Details |
| D377 | TRO19622 | Chemical drug | DB05185 | mPTP | -- | Under clinical trials | Details |
| D378 | Troglitazone | Chemical drug | DB00197 | PPARG agonist; PPARD; PPARA | Improve insulin resistance | Under investigation | Details |
| D379 | Tropifexor | Chemical drug | DB16343 | FXR agonist | Enhance lipid metabolism | Under clinical trials | Details |
| D380 | TVB-2640 | Chemical drug | -- | FASN inhibitor | Enhance lipid metabolism; Anticancer agent | Under clinical trials | Details |
| D381 | Ursodeoxycholic acid | Chemical drug | DB01586 | AKR1C2 inducer | Anti-inflammatory | Under clinical trials | Details |
| D382 | Vigabatrin | Chemical drug | DB01080 | GABBR1 agonist; ABAT inhibitor | Antiepileptic drug | Under clinical trials | Details |
| D383 | Vildagliptin | Chemical drug | DB04876 | DPP4 inhibitor | Antidiabetic drug | Under clinical trials | Details |
| D384 | Vitamin B12 | Supplement | DB00115 | MTHFR cofactor | -- | Under clinical trials | Details |
| D385 | Vitamin B6 | Supplement | DB00165 | PDXK ligand | -- | Under clinical trials | Details |
| D386 | Vitamin C | Supplement | DB00126 | PLOD2 cofactor; PLOD3 cofactor; DBH cofactor; P3H1 cofactor; P3H2 cofactor; P3H3 cofactor; PLOD1 cofactor | -- | Under clinical trials | Details |
| D387 | Vitamin D | Supplement | DB11094 | -- | Vitamin source drug | Under clinical trials | Details |
| D388 | Vitamin E | Supplement | DB00163 | NR1I2; ALOX5; DGKA | Anti-inflammatory | Under clinical trials | Details |
| D389 | Viusid | Supplement | -- | -- | Antioxidant drug | Under clinical trials | Details |
| D390 | VK-2809 | Chemical drug | DB15137 | THR agonist | Anti-fibrosis | Under clinical trials | Details |
| D391 | VSL#3 | Biological drug | -- | TCPTP activator | Probiotics | Failed in clinical trials | Details |
| D392 | Yaq-001 | Miscellany | -- | -- | -- | Under clinical trials | Details |
| D393 | YiQiSanJu | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D394 | CJHR | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D395 | Zinc | Chemical drug | DB01593 | PSPH; CCS; HDAC1 cofactor; HDAC4 cofactor; INS; UTRN; ASPA cofactor; TP73 cofactor; A2M; AGT; APOBR; APOE; APOL1; C3; C5; CFB; CFH; CFI; CLU; CP; CPN2; DSP; F12; F13B; FGA; GSN; HBB; HPR; JUP; SELENOP; TTR; VTN | -- | Under clinical trials | Details |
| D396 | ZSP0678 | Chemical drug | -- | -- | Hepatoprotectants | Under clinical trials | Details |
| D397 | ZSP1601 | Chemical drug | -- | PDE inhibitor | Hepatoprotectants | Under clinical trials | Details |
| D398 | Zucchini | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D399 | β-glucan | Chemical drug | -- | Cr3 modulator | Anticancer agent | Under clinical trials | Details |
| D400 | Eltrombopag | Chemical drug | DB06210 | -- | -- | Under clinical trials | Details |
| D401 | A mixture of Huangqi, Huanglian, Zexie, Yujin, Zhidahuang, Shanzha, Maiya, Zhizhi, Huangqin and Yincheng | Herbal medicine | -- | -- | -- | Under clinical trials | Details |
| D402 | A mixture of Anethum graveolens, Citrus bigardia, Cynara scolymus, Portulaca oleracea, and Silybum marianum | Herbal medicine | -- | -- | -- | Under clinical trials | Details |