Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Obesity46 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0068 | DB00182 | approved; illicit; investigational | small molecule | Amphetamine | Indication associated | Details |
| R0098 | DB00264 | approved; investigational | small molecule | Metoprolol | Therapeutic strategy associated | Details |
| R0118 | DB00333 | approved | small molecule | Methadone | Therapeutic strategy associated | Details |
| R0140 | DB00397 | approved; vet_approved; withdrawn | small molecule | Phenylpropanolamine | Indication associated | Details |
| R0298 | DB00830 | approved; illicit | small molecule | Phenmetrazine | Indication associated | Details |
| R0313 | DB00865 | approved; illicit | small molecule | Benzphetamine | Therapeutic strategy associated | Details |
| R0339 | DB00937 | approved; illicit | small molecule | Diethylpropion | Indication associated | Details |
| R0439 | DB01191 | approved; illicit; investigational; withdrawn | small molecule | Dexfenfluramine | Therapeutic strategy associated | Details |
| R0469 | DB01255 | approved; investigational | small molecule | Lisdexamfetamine | Indication associated | Details |
| R0527 | DB01550 | experimental; illicit; withdrawn | small molecule | Fenproporex | Indication associated | Details |
| R0530 | DB01577 | approved; illicit | small molecule | Metamfetamine | Indication associated | Details |
| R0531 | DB01579 | approved; illicit | small molecule | Phendimetrazine | Therapeutic strategy associated | Details |
| R0554 | DB01783 | approved; nutraceutical; vet_approved | small molecule | Pantothenic acid | Indication associated | Details |
| R0589 | DB03604 | investigational | small molecule | Tiratricol | Target associated | Details |
| R0631 | DB04870 | investigational | small molecule | Oleoyl-estrone | Indication associated | Details |
| R0632 | DB04871 | approved | small molecule | Lorcaserin | Therapeutic strategy associated | Details |
| R0655 | DB04936 | investigational | small molecule | Tagatose | Indication associated | Details |
| R0675 | DB05004 | investigational | small molecule | Peptide YY (3-36) | Indication associated | Details |
| R0681 | DB05035 | investigational | small molecule | Eprotirome | Target associated | Details |
| R0683 | DB05045 | investigational | small molecule | Obinepitide | Indication associated | Details |
| R0694 | DB05077 | investigational | small molecule | SLV319 | Indication associated | Details |
| R0695 | DB05080 | investigational | small molecule | OBE101 | Indication associated | Details |
| R0700 | DB05098 | investigational | small molecule | Leptin | Therapeutic strategy associated | Details |
| R0727 | DB05188 | investigational | small molecule | KD3010 | Target associated | Details |
| R0733 | DB05201 | investigational | small molecule | V24343 | Therapeutic strategy associated | Details |
| R0782 | DB05395 | investigational | small molecule | Amibegron | Indication associated | Details |
| R0789 | DB05416 | investigational | small molecule | Cardarine | Target associated | Details |
| R0821 | DB05506 | investigational | small molecule | ISIS 113715 | Therapeutic strategy associated | Details |
| R0861 | DB05750 | investigational | small molecule | AVE-1625 | Indication associated | Details |
| R0875 | DB05804 | investigational | small molecule | Prasterone sulfate | Therapeutic strategy associated | Details |
| R0895 | DB05894 | investigational | small molecule | GT 389-255 | Therapeutic strategy associated | Details |
| R0913 | DB05993 | investigational | small molecule | PRX-07034 | Therapeutic strategy associated | Details |
| R0934 | DB06156 | investigational | small molecule | Tesofensine | Indication associated | Details |
| R0958 | DB06250 | investigational | small molecule | Fluasterone | Therapeutic strategy associated | Details |
| R0984 | DB06333 | investigational | small molecule | Trodusquemine | Therapeutic strategy associated | Details |
| R0991 | DB06358 | investigational | small molecule | Iclaprim | Indication associated | Details |
| R1046 | DB06569 | investigational | small molecule | P-57AS3 | Indication associated | Details |
| R1049 | DB06586 | investigational | small molecule | Cetilistat | Therapeutic strategy associated | Details |
| R1065 | DB06624 | investigational | small molecule | Taranabant | Indication associated | Details |
| R1170 | DB08862 | approved; investigational | small molecule | Cholecystokinin | Therapeutic strategy associated | Details |
| R1319 | DB09568 | approved; investigational | small molecule | Omega-3-carboxylic acids | Therapeutic strategy associated | Details |
| R1379 | DB11584 | approved | small molecule | Pipradrol | Therapeutic strategy associated | Details |
| R1393 | DB11700 | approved; investigational | small molecule | Setmelanotide | Therapeutic strategy associated | Details |
| R1410 | DB11827 | approved; investigational | small molecule | Ertugliflozin | Target associated | Details |
| R1485 | DB13174 | experimental | small molecule | Rhein | Therapeutic strategy associated | Details |
| R1568 | DB15661 | investigational | small molecule | Molnupiravir | Indication associated | Details |