Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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platelet aggregation64 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0018 | DB00054 | approved | biotech | Abciximab | Therapeutic strategy associated | Details |
| R0019 | DB00063 | approved; investigational | biotech | Eptifibatide | Therapeutic strategy associated | Details |
| R0043 | DB00132 | approved; investigational; nutraceutical | small molecule | alpha-Linolenic acid | Therapeutic strategy associated | Details |
| R0054 | DB00154 | investigational; nutraceutical | small molecule | Dihomo-gamma-linolenic acid | Therapeutic strategy associated | Details |
| R0056 | DB00159 | approved; nutraceutical | small molecule | Icosapent | Therapeutic strategy associated | Details |
| R0078 | DB00208 | approved | small molecule | Ticlopidine | Therapeutic strategy associated | Details |
| R0096 | DB00261 | approved | small molecule | Anagrelide | Therapeutic strategy associated | Details |
| R0101 | DB00278 | approved; investigational | small molecule | Argatroban | Therapeutic strategy associated | Details |
| R0111 | DB00310 | approved | small molecule | Chlorthalidone | Therapeutic strategy associated | Details |
| R0134 | DB00374 | approved; investigational | small molecule | Treprostinil | Therapeutic strategy associated | Details |
| R0154 | DB00460 | approved; investigational | small molecule | Verteporfin | Therapeutic strategy associated | Details |
| R0155 | DB00461 | approved | small molecule | Nabumetone | Therapeutic strategy associated | Details |
| R0156 | DB00464 | approved; investigational | small molecule | Sodium tetradecyl sulfate | Therapeutic strategy associated | Details |
| R0165 | DB00482 | approved; investigational | small molecule | Celecoxib | Therapeutic strategy associated | Details |
| R0179 | DB00533 | approved; investigational; withdrawn | small molecule | Rofecoxib | Therapeutic strategy associated | Details |
| R0200 | DB00580 | approved; investigational; withdrawn | small molecule | Valdecoxib | Therapeutic strategy associated | Details |
| R0246 | DB00699 | approved; investigational | small molecule | Nicergoline | Therapeutic strategy associated | Details |
| R0266 | DB00758 | approved | small molecule | Clopidogrel | Therapeutic strategy associated | Details |
| R0277 | DB00775 | approved | small molecule | Tirofiban | Therapeutic strategy associated | Details |
| R0288 | DB00808 | approved | small molecule | Indapamide | Therapeutic strategy associated | Details |
| R0350 | DB00975 | approved | small molecule | Dipyridamole | Therapeutic strategy associated | Details |
| R0394 | DB01079 | approved; investigational; withdrawn | small molecule | Tegaserod | Therapeutic strategy associated | Details |
| R0396 | DB01088 | approved; investigational | small molecule | Iloprost | Therapeutic strategy associated | Details |
| R0461 | DB01240 | approved | small molecule | Epoprostenol | Therapeutic strategy associated | Details |
| R0504 | DB01377 | approved | small molecule | Magnesium oxide | Therapeutic strategy associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0513 | DB01401 | approved | small molecule | Choline magnesium trisalicylate | Therapeutic strategy associated | Details |
| R0567 | DB02638 | approved; investigational | small molecule | Terlipressin | Therapeutic strategy associated | Details |
| R0630 | DB04863 | investigational | small molecule | Lefradafiban | Therapeutic strategy associated | Details |
| R0652 | DB04932 | approved; investigational | biotech | Defibrotide | Therapeutic strategy associated | Details |
| R0668 | DB04980 | investigational | small molecule | Lemuteporfin | Therapeutic strategy associated | Details |
| R0679 | DB05027 | investigational | small molecule | DG041 | Therapeutic strategy associated | Details |
| R0701 | DB05099 | approved; investigational | biotech | Ancrod | Therapeutic strategy associated | Details |
| R0734 | DB05202 | investigational | biotech | Egaptivon pegol | Target associated | Details |
| R0745 | DB05227 | investigational | small molecule | APD791 | Therapeutic strategy associated | Details |
| R0871 | DB05777 | approved; investigational | biotech | Thrombomodulin Alfa | Therapeutic strategy associated | Details |
| R0921 | DB06081 | approved; investigational | biotech | Caplacizumab | Therapeutic strategy associated | Details |
| R0945 | DB06209 | approved | small molecule | Prasugrel | Therapeutic strategy associated | Details |
| R0990 | DB06350 | investigational | small molecule | Elinogrel | Indication associated | Details |
| R1015 | DB06441 | approved | small molecule | Cangrelor | Therapeutic strategy associated | Details |
| R1025 | DB06472 | investigational | small molecule | Fradafiban | Therapeutic strategy associated | Details |
| R1157 | DB08816 | approved | small molecule | Ticagrelor | Therapeutic strategy associated | Details |
| R1193 | DB09012 | experimental; withdrawn | small molecule | Carbazochrome | Therapeutic strategy associated | Details |
| R1196 | DB09030 | approved | small molecule | Vorapaxar | Therapeutic strategy associated | Details |
| R1237 | DB09166 | experimental | small molecule | Etizolam | Therapeutic strategy associated | Details |
| R1242 | DB09210 | approved; investigational | small molecule | Piracetam | Therapeutic strategy associated | Details |
| R1243 | DB09212 | approved | small molecule | Loxoprofen | Therapeutic strategy associated | Details |
| R1281 | DB09282 | approved; investigational | small molecule | Molsidomine | Therapeutic strategy associated | Details |
| R1330 | DB11086 | approved | biotech | Cocoa butter | Therapeutic strategy associated | Details |
| R1332 | DB11095 | approved | biotech | Desirudin | Therapeutic strategy associated | Details |
| R1360 | DB11265 | nutraceutical | biotech | Curcuma xanthorrhiza oil | Therapeutic strategy associated | Details |
| R1370 | DB11362 | approved | small molecule | Selexipag | Therapeutic strategy associated | Details |
| R1373 | DB11386 | approved; investigational; vet_approved | small molecule | Chlorobutanol | Therapeutic strategy associated | Details |
| R1440 | DB12249 | approved; investigational | biotech | Stem bromelain | Therapeutic strategy associated | Details |
| R1445 | DB12364 | approved; investigational | small molecule | Betrixaban | Therapeutic strategy associated | Details |
| R1483 | DB13168 | nutraceutical | small molecule | Omega-6 fatty acids | Therapeutic strategy associated | Details |
| R1489 | DB13345 | approved; experimental | small molecule | Dihydroergocristine | Therapeutic strategy associated | Details |
| R1495 | DB13783 | approved; investigational | small molecule | Acemetacin | Therapeutic strategy associated | Details |
| R1496 | DB13854 | approved; investigational | small molecule | Gamolenic acid | Therapeutic strategy associated | Details |
| R1498 | DB13891 | approved; experimental | biotech | Crotalus scutulatus antivenin | Therapeutic strategy associated | Details |
| R1508 | DB14001 | approved; nutraceutical; vet_approved | small molecule | alpha-Tocopherol succinate | Therapeutic strategy associated | Details |
| R1509 | DB14002 | approved; nutraceutical; vet_approved | small molecule | D-alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
| R1510 | DB14003 | approved | small molecule | alpha-Tocopherol acetate | Therapeutic strategy associated | Details |
| R1535 | DB14635 | experimental | small molecule | Curcumin sulfate | Therapeutic strategy associated | Details |