Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1401 | DB11755 | investigational | small molecule | Tetrahydrocannabivarin | Therapeutic strategy associated | Details |
| R1402 | DB11761 | approved; investigational | small molecule | Tenapanor | Indication associated | Details |
| R1403 | DB11772 | investigational | small molecule | Pilaralisib | Therapeutic strategy associated | Details |
| R1404 | DB11776 | approved; investigational | biotech | Brodalumab | Therapeutic strategy associated | Details |
| R1405 | DB11781 | investigational | small molecule | Tosedostat | Therapeutic strategy associated | Details |
| R1406 | DB11793 | approved; investigational | small molecule | Niraparib | Therapeutic strategy associated | Details |
| R1407 | DB11811 | investigational | small molecule | Arhalofenate | Target associated | Details |
| R1408 | DB11817 | approved; investigational | small molecule | Baricitinib | Therapeutic strategy associated | Details |
| R1409 | DB11823 | approved; investigational | small molecule | Esketamine | Indication associated | Details |
| R1410 | DB11827 | approved; investigational | small molecule | Ertugliflozin | Target associated | Details |
| R1411 | DB11830 | investigational | small molecule | Mocetinostat | Therapeutic strategy associated | Details |
| R1412 | DB11834 | approved; investigational | biotech | Guselkumab | Therapeutic strategy associated | Details |
| R1413 | DB11842 | approved; investigational | small molecule | Angiotensin II | Target associated | Details |
| R1414 | DB11856 | investigational | biotech | Ligelizumab | Therapeutic strategy associated | Details |
| R1415 | DB11859 | approved; investigational | small molecule | Brexanolone | Indication associated | Details |
| R1416 | DB11866 | approved; investigational | biotech | Romosozumab | Indication associated | Details |
| R1417 | DB11921 | approved; investigational | small molecule | Deflazacort | Therapeutic strategy associated | Details |
| R1418 | DB11928 | approved; investigational | biotech | Vosoritide | Therapeutic strategy associated | Details |
| R1419 | DB11936 | approved; investigational | small molecule | Bempedoic acid | Indication associated | Details |
| R1420 | DB11942 | approved; investigational | small molecule | Selinexor | Therapeutic strategy associated | Details |
| R1421 | DB11943 | approved; investigational | small molecule | Delafloxacin | Indication associated | Details |
| R1422 | DB11952 | approved; investigational | small molecule | Duvelisib | Therapeutic strategy associated | Details |
| R1423 | DB11967 | approved; investigational | small molecule | Binimetinib | Therapeutic strategy associated | Details |
| R1424 | DB11976 | approved; investigational | biotech | Anifrolumab | Therapeutic strategy associated | Details |
| R1425 | DB11986 | approved; investigational | small molecule | Entrectinib | Therapeutic strategy associated | Details |
| R1426 | DB11988 | approved; investigational | biotech | Ocrelizumab | Therapeutic strategy associated | Details |
| R1427 | DB12007 | experimental | small molecule | Isoflavone | Therapeutic strategy associated | Details |
| R1428 | DB12010 | approved; investigational | small molecule | Fostamatinib | Target associated | Details |
| R1429 | DB12023 | approved; investigational | biotech | Benralizumab | Therapeutic strategy associated | Details |
| R1430 | DB12035 | approved; investigational | small molecule | Sarecycline | Therapeutic strategy associated | Details |
| R1431 | DB12077 | investigational | biotech | Urelumab | Target associated | Details |
| R1432 | DB12107 | approved; investigational | small molecule | Vaborbactam | Indication associated | Details |
| R1433 | DB12140 | investigational | small molecule | Dilmapimod | Therapeutic strategy associated | Details |
| R1434 | DB12147 | approved; investigational | small molecule | Erdafitinib | Therapeutic strategy associated | Details |
| R1435 | DB12157 | investigational | biotech | Fasinumab | Therapeutic strategy associated | Details |
| R1436 | DB12159 | approved; investigational | biotech | Dupilumab | Therapeutic strategy associated | Details |
| R1437 | DB12169 | approved; investigational | biotech | Tralokinumab | Therapeutic strategy associated | Details |
| R1438 | DB12240 | approved; investigational | biotech | Polatuzumab vedotin | Therapeutic strategy associated | Details |
| R1439 | DB12243 | approved; investigational | small molecule | Edaravone | Therapeutic strategy associated | Details |
| R1440 | DB12249 | approved; investigational | biotech | Stem bromelain | Therapeutic strategy associated | Details |
| R1441 | DB12281 | approved; investigational | biotech | Luspatercept | Therapeutic strategy associated | Details |
| R1442 | DB12328 | approved; investigational | small molecule | Cantharidin | Therapeutic strategy associated | Details |
| R1443 | DB12332 | approved; investigational | small molecule | Rucaparib | Therapeutic strategy associated | Details |
| R1444 | DB12340 | investigational | small molecule | Navitoclax | Therapeutic strategy associated | Details |
| R1445 | DB12364 | approved; investigational | small molecule | Betrixaban | Therapeutic strategy associated | Details |
| R1446 | DB12371 | approved; investigational | small molecule | Siponimod | Therapeutic strategy associated | Details |
| R1447 | DB12442 | investigational | small molecule | Alvespimycin | Therapeutic strategy associated | Details |
| R1448 | DB12455 | approved; investigational | small molecule | Omadacycline | Indication associated | Details |
| R1449 | DB12483 | approved; investigational | small molecule | Copanlisib | Therapeutic strategy associated | Details |
| R1450 | DB12499 | approved; investigational | small molecule | Clascoterone | Therapeutic strategy associated | Details |
| R1451 | DB12500 | approved; investigational | small molecule | Fedratinib | Therapeutic strategy associated | Details |
| R1452 | DB12520 | investigational | biotech | Plozalizumab | Target associated | Details |
| R1453 | DB12530 | approved; investigational | biotech | Inebilizumab | Therapeutic strategy associated | Details |
| R1454 | DB12565 | investigational | small molecule | Abexinostat | Therapeutic strategy associated | Details |
| R1455 | DB12589 | investigational | biotech | Dacetuzumab | Target associated | Details |
| R1456 | DB12592 | investigational | small molecule | Mosedipimod | Therapeutic strategy associated | Details |
| R1457 | DB12598 | investigational | small molecule | Nafamostat | Therapeutic strategy associated | Details |
| R1458 | DB12651 | investigational | small molecule | Bardoxolone | Therapeutic strategy associated | Details |
| R1459 | DB12662 | investigational | small molecule | Naveglitazar | Target associated | Details |
| R1460 | DB12698 | approved; investigational | biotech | Ibalizumab | Target associated | Details |
| R1461 | DB12764 | investigational | small molecule | Opaganib | Therapeutic strategy associated | Details |
| R1462 | DB12783 | approved; investigational | small molecule | Benserazide | Therapeutic strategy associated | Details |
| R1463 | DB12808 | approved; investigational | small molecule | Trifarotene | Therapeutic strategy associated | Details |
| R1464 | DB12825 | approved; investigational | small molecule | Lefamulin | Indication associated | Details |
| R1465 | DB12831 | investigational | small molecule | Gabexate | Therapeutic strategy associated | Details |
| R1466 | DB12836 | investigational; vet_approved | small molecule | Grapiprant | Indication associated | Details |
| R1467 | DB12911 | approved; investigational | small molecule | Nicoboxil | Indication associated | Details |
| R1468 | DB12942 | approved; investigational | small molecule | Lactitol | Indication associated | Details |
| R1469 | DB12960 | investigational | small molecule | INCB-9471 | Target associated | Details |
| R1470 | DB12961 | investigational | small molecule | Leukotriene B4 | Target associated | Details |
| R1471 | DB12965 | approved; investigational | small molecule | Silver | Therapeutic strategy associated | Details |
| R1472 | DB13007 | approved; investigational | biotech | Enfortumab vedotin | Therapeutic strategy associated | Details |
| R1473 | DB13037 | investigational | biotech | Namilumab | Therapeutic strategy associated | Details |
| R1474 | DB13142 | approved | small molecule | Calcium glubionate anhydrous | Indication associated | Details |
| R1475 | DB13145 | approved; investigational | small molecule | Nedaplatin | Therapeutic strategy associated | Details |
| R1476 | DB13149 | approved | biotech | Protein S human | Therapeutic strategy associated | Details |
| R1477 | DB13153 | approved; experimental | small molecule | Levomenol | Therapeutic strategy associated | Details |
| R1478 | DB13155 | approved | small molecule | Esculin | Therapeutic strategy associated | Details |
| R1479 | DB13158 | approved | small molecule | Clobetasone | Therapeutic strategy associated | Details |
| R1480 | DB13163 | approved; experimental | small molecule | Terpin hydrate | Indication associated | Details |
| R1481 | DB13165 | experimental | small molecule | Ripasudil | Indication associated | Details |
| R1482 | DB13167 | approved; withdrawn | small molecule | Alclofenac | Therapeutic strategy associated | Details |
| R1483 | DB13168 | nutraceutical | small molecule | Omega-6 fatty acids | Therapeutic strategy associated | Details |
| R1484 | DB13170 | approved; investigational | small molecule | Plecanatide | Therapeutic strategy associated | Details |
| R1485 | DB13174 | experimental | small molecule | Rhein | Therapeutic strategy associated | Details |
| R1486 | DB13178 | approved; investigational; withdrawn | small molecule | Inositol | Therapeutic strategy associated | Details |
| R1487 | DB13179 | approved | small molecule | Troleandomycin | Indication associated | Details |
| R1488 | DB13191 | nutraceutical | small molecule | Phosphocreatine | Indication associated | Details |
| R1489 | DB13345 | approved; experimental | small molecule | Dihydroergocristine | Therapeutic strategy associated | Details |
| R1490 | DB13346 | approved; withdrawn | small molecule | Bufexamac | Therapeutic strategy associated | Details |
| R1491 | DB13501 | approved; withdrawn | small molecule | Bendazac | Therapeutic strategy associated | Details |
| R1492 | DB13615 | approved; experimental | small molecule | Mifamurtide | Therapeutic strategy associated | Details |
| R1493 | DB13749 | approved; investigational | small molecule | Magnesium gluconate | Indication associated | Details |
| R1494 | DB13751 | approved; experimental | small molecule | Glycyrrhizic acid | Therapeutic strategy associated | Details |
| R1495 | DB13783 | approved; investigational | small molecule | Acemetacin | Therapeutic strategy associated | Details |
| R1496 | DB13854 | approved; investigational | small molecule | Gamolenic acid | Therapeutic strategy associated | Details |
| R1497 | DB13873 | approved | small molecule | Fenofibric acid | Target associated | Details |
| R1498 | DB13891 | approved; experimental | biotech | Crotalus scutulatus antivenin | Therapeutic strategy associated | Details |
| R1499 | DB13906 | experimental | biotech | Aloe vera leaf | Therapeutic strategy associated | Details |
| R1500 | DB13908 | approved | small molecule | Amylmetacresol | Therapeutic strategy associated | Details |