Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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inflammatory457 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0809 | DB05470 | investigational | small molecule | VX-702 | Target associated | Details |
| R0810 | DB05474 | investigational | small molecule | T487 | Indication associated | Details |
| R0812 | DB05479 | investigational | small molecule | CZEN 002 | Therapeutic strategy associated | Details |
| R0813 | DB05484 | investigational | small molecule | MDX-018 | Therapeutic strategy associated | Details |
| R0822 | DB05507 | investigational | small molecule | VX-765 | Therapeutic strategy associated | Details |
| R0823 | DB05511 | investigational | small molecule | Piclidenoson | Therapeutic strategy associated | Details |
| R0837 | DB05616 | investigational | small molecule | 4'-Methylene-5,8,10-trideazaaminopterin | Indication associated | Details |
| R0845 | DB05671 | investigational | biotech | AC-100 | Therapeutic strategy associated | Details |
| R0846 | DB05676 | approved; investigational | small molecule | Apremilast | Therapeutic strategy associated | Details |
| R0848 | DB05679 | approved; investigational | biotech | Ustekinumab | Therapeutic strategy associated | Details |
| R0849 | DB05685 | investigational | biotech | FX06 | Therapeutic strategy associated | Details |
| R0850 | DB05688 | investigational | small molecule | CRx-119 | Therapeutic strategy associated | Details |
| R0853 | DB05730 | investigational | small molecule | PMI-001 | Therapeutic strategy associated | Details |
| R0859 | DB05744 | investigational | small molecule | CRx-139 | Therapeutic strategy associated | Details |
| R0862 | DB05754 | investigational | small molecule | IPH 1101 | Therapeutic strategy associated | Details |
| R0864 | DB05758 | investigational | biotech | CYT007-TNFQb | Therapeutic strategy associated | Details |
| R0865 | DB05767 | investigational | small molecule | Andrographolide | Therapeutic strategy associated | Details |
| R0866 | DB05768 | investigational | small molecule | Alkaline Phosphatase | Therapeutic strategy associated | Details |
| R0870 | DB05775 | investigational | small molecule | CRx-401 | Indication associated | Details |
| R0871 | DB05777 | approved; investigational | biotech | Thrombomodulin Alfa | Therapeutic strategy associated | Details |
| R0872 | DB05787 | investigational | biotech | LM-609 | Therapeutic strategy associated | Details |
| R0873 | DB05792 | investigational | small molecule | Arylacenamide | Therapeutic strategy associated | Details |
| R0880 | DB05825 | investigational | small molecule | NCX 1015 | Therapeutic strategy associated | Details |
| R0883 | DB05840 | investigational | small molecule | AGI-1096 | Therapeutic strategy associated | Details |
| R0885 | DB05849 | investigational | small molecule | NCX 950 | Therapeutic strategy associated | Details |
| R0889 | DB05869 | investigational | small molecule | Ethyl pyruvate | Therapeutic strategy associated | Details |
| R0890 | DB05879 | investigational | biotech | AME-527 | Therapeutic strategy associated | Details |
| R0894 | DB05892 | investigational | biotech | RI 624 | Therapeutic strategy associated | Details |
| R0902 | DB05943 | investigational | small molecule | Resatorvid | Therapeutic strategy associated | Details |
| R0909 | DB05973 | investigational | small molecule | Inosine 5'-sulfate | Indication associated | Details |
| R0911 | DB05983 | investigational | small molecule | Bardoxolone methyl | Therapeutic strategy associated | Details |
| R0936 | DB06168 | approved; investigational | biotech | Canakinumab | Therapeutic strategy associated | Details |
| R0947 | DB06224 | investigational | small molecule | Alicaforsen | Therapeutic strategy associated | Details |
| R0948 | DB06225 | investigational | small molecule | HMR4011 | Therapeutic strategy associated | Details |
| R0958 | DB06250 | investigational | small molecule | Fluasterone | Therapeutic strategy associated | Details |
| R0968 | DB06271 | approved; investigational | biotech | Sulodexide | Therapeutic strategy associated | Details |
| R0969 | DB06273 | approved | biotech | Tocilizumab | Therapeutic strategy associated | Details |
| R0972 | DB06283 | approved | small molecule | Ziconotide | Therapeutic strategy associated | Details |
| R0975 | DB06297 | investigational | small molecule | LX-2931 | Indication associated | Details |
| R0977 | DB06309 | investigational | small molecule | Refametinib | Therapeutic strategy associated | Details |
| R0978 | DB06311 | investigational | small molecule | Darapladib | Therapeutic strategy associated | Details |
| R0986 | DB06343 | approved; investigational | biotech | Teprotumumab | Therapeutic strategy associated | Details |
| R0987 | DB06345 | investigational | small molecule | AR-9281 | Therapeutic strategy associated | Details |
| R0988 | DB06346 | investigational | small molecule | Fiboflapon | Therapeutic strategy associated | Details |
| R0994 | DB06366 | approved | biotech | Pertuzumab | Therapeutic strategy associated | Details |
| R0996 | DB06372 | approved; investigational | biotech | Rilonacept | Therapeutic strategy associated | Details |
| R0998 | DB06379 | investigational | biotech | Calcitonin gene-related peptide | Therapeutic strategy associated | Details |
| R1005 | DB06405 | investigational | small molecule | Eprodisate | Therapeutic strategy associated | Details |
| R1008 | DB06421 | investigational | small molecule | Declopramide | Therapeutic strategy associated | Details |
| R1018 | DB06448 | approved; investigational | small molecule | Lonafarnib | Therapeutic strategy associated | Details |
| R1019 | DB06449 | investigational | small molecule | Ilodecakin | Indication associated | Details |
| R1030 | DB06495 | investigational | biotech | Onercept | Therapeutic strategy associated | Details |
| R1032 | DB06503 | investigational | biotech | MLN2222 | Therapeutic strategy associated | Details |
| R1044 | DB06546 | investigational | biotech | Atibuclimab | Therapeutic strategy associated | Details |
| R1055 | DB06602 | approved; investigational | biotech | Reslizumab | Therapeutic strategy associated | Details |
| R1059 | DB06607 | approved; investigational; withdrawn | biotech | Catumaxomab | Therapeutic strategy associated | Details |
| R1063 | DB06612 | approved; investigational | biotech | Mepolizumab | Therapeutic strategy associated | Details |
| R1076 | DB06674 | approved | biotech | Golimumab | Therapeutic strategy associated | Details |
| R1079 | DB06682 | investigational | small molecule | Naproxcinod | Indication associated | Details |
| R1080 | DB06689 | approved | small molecule | Ethanolamine oleate | Therapeutic strategy associated | Details |
| R1081 | DB06692 | approved; investigational; withdrawn | biotech | Aprotinin | Therapeutic strategy associated | Details |
| R1085 | DB06709 | approved; investigational | small molecule | Methacholine | Therapeutic strategy associated | Details |
| R1087 | DB06725 | approved; investigational | small molecule | Lornoxicam | Therapeutic strategy associated | Details |
| R1089 | DB06736 | approved; investigational | small molecule | Aceclofenac | Therapeutic strategy associated | Details |
| R1090 | DB06742 | approved; investigational | small molecule | Ambroxol | Therapeutic strategy associated | Details |
| R1098 | DB06781 | approved | small molecule | Difluprednate | Therapeutic strategy associated | Details |
| R1099 | DB06784 | approved | small molecule | Gallium citrate Ga-67 | Therapeutic strategy associated | Details |
| R1100 | DB06786 | approved; investigational; withdrawn | small molecule | Halcinonide | Therapeutic strategy associated | Details |
| R1101 | DB06789 | approved; investigational | small molecule | Hydroxyprogesterone caproate | Therapeutic strategy associated | Details |
| R1105 | DB06812 | approved | small molecule | Povidone-iodine | Therapeutic strategy associated | Details |
| R1158 | DB08818 | approved; vet_approved | small molecule | Hyaluronic acid | Therapeutic strategy associated | Details |
| R1165 | DB08835 | experimental | small molecule | Spaglumic acid | Therapeutic strategy associated | Details |
| R1169 | DB08844 | investigational | small molecule | Uric acid | Therapeutic strategy associated | Details |
| R1174 | DB08877 | approved | small molecule | Ruxolitinib | Therapeutic strategy associated | Details |
| R1176 | DB08880 | approved | small molecule | Teriflunomide | Therapeutic strategy associated | Details |
| R1181 | DB08895 | approved; investigational | small molecule | Tofacitinib | Therapeutic strategy associated | Details |
| R1183 | DB08904 | approved | biotech | Certolizumab pegol | Therapeutic strategy associated | Details |
| R1184 | DB08908 | approved; investigational | small molecule | Dimethyl fumarate | Therapeutic strategy associated | Details |
| R1185 | DB08910 | approved | small molecule | Pomalidomide | Therapeutic strategy associated | Details |
| R1190 | DB08949 | approved; withdrawn | small molecule | Inositol nicotinate | Therapeutic strategy associated | Details |
| R1203 | DB09052 | approved; investigational | biotech | Blinatumomab | Therapeutic strategy associated | Details |
| R1206 | DB09059 | approved; investigational | small molecule | Atosiban | Therapeutic strategy associated | Details |
| R1208 | DB09061 | approved; investigational | small molecule | Cannabidiol | Therapeutic strategy associated | Details |
| R1216 | DB09084 | approved | small molecule | Benzydamine | Therapeutic strategy associated | Details |
| R1217 | DB09086 | approved | small molecule | Eugenol | Therapeutic strategy associated | Details |
| R1222 | DB09095 | approved; investigational; withdrawn | small molecule | Difluocortolone | Therapeutic strategy associated | Details |
| R1223 | DB09099 | approved; investigational | small molecule | Somatostatin | Therapeutic strategy associated | Details |
| R1226 | DB09110 | approved; investigational | small molecule | Coenzyme M | Therapeutic strategy associated | Details |
| R1228 | DB09120 | approved; investigational | small molecule | Zucapsaicin | Therapeutic strategy associated | Details |
| R1229 | DB09121 | approved; withdrawn | small molecule | Aurothioglucose | Therapeutic strategy associated | Details |
| R1230 | DB09124 | approved; withdrawn | small molecule | Medrogestone | Therapeutic strategy associated | Details |
| R1235 | DB09163 | approved | small molecule | Technetium Tc-99m exametazime | Indication associated | Details |
| R1243 | DB09212 | approved | small molecule | Loxoprofen | Therapeutic strategy associated | Details |
| R1244 | DB09213 | approved; investigational | small molecule | Dexibuprofen | Therapeutic strategy associated | Details |
| R1245 | DB09214 | approved; investigational | small molecule | Dexketoprofen | Therapeutic strategy associated | Details |
| R1246 | DB09215 | withdrawn | small molecule | Droxicam | Therapeutic strategy associated | Details |
| R1247 | DB09216 | approved; investigational | small molecule | Tolfenamic acid | Therapeutic strategy associated | Details |
| R1248 | DB09218 | experimental | small molecule | Clonixin | Therapeutic strategy associated | Details |
| R1251 | DB09221 | experimental | small molecule | Polaprezinc | Therapeutic strategy associated | Details |
| R1258 | DB09236 | approved; investigational | small molecule | Lacidipine | Therapeutic strategy associated | Details |