Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0701 | DB05099 | approved; investigational | biotech | Ancrod | Therapeutic strategy associated | Details |
| R0702 | DB05103 | investigational | small molecule | AN-9 | Therapeutic strategy associated | Details |
| R0703 | DB05104 | investigational | small molecule | Asimadoline | Indication associated | Details |
| R0704 | DB05115 | investigational | small molecule | NN344 | Indication associated | Details |
| R0705 | DB05118 | investigational | small molecule | R1204 | Indication associated | Details |
| R0706 | DB05119 | investigational | small molecule | Rilapladib | Indication associated | Details |
| R0707 | DB05120 | investigational | small molecule | AT1391 | Indication associated | Details |
| R0708 | DB05122 | investigational | small molecule | R1295 | Therapeutic strategy associated | Details |
| R0709 | DB05125 | investigational | small molecule | SC12267 | Indication associated | Details |
| R0710 | DB05126 | investigational | small molecule | PYM50018 | Therapeutic strategy associated | Details |
| R0711 | DB05130 | investigational | small molecule | INCB3284 | Target associated | Details |
| R0712 | DB05132 | investigational | small molecule | ND1251 | Indication associated | Details |
| R0713 | DB05133 | investigational | small molecule | VP025 | Therapeutic strategy associated | Details |
| R0714 | DB05136 | investigational | biotech | Bavituximab | Therapeutic strategy associated | Details |
| R0715 | DB05140 | investigational | biotech | RAV12 | Therapeutic strategy associated | Details |
| R0716 | DB05141 | investigational | small molecule | LY2181308 | Therapeutic strategy associated | Details |
| R0717 | DB05142 | investigational | small molecule | ND7001 | Indication associated | Details |
| R0718 | DB05145 | investigational | biotech | TH0318 | Indication associated | Details |
| R0719 | DB05157 | investigational | small molecule | KC706 | Therapeutic strategy associated | Details |
| R0720 | DB05159 | investigational | small molecule | CCX915 | Therapeutic strategy associated | Details |
| R0721 | DB05161 | investigational | small molecule | Elafin | Therapeutic strategy associated | Details |
| R0722 | DB05166 | investigational | small molecule | APD668 | Indication associated | Details |
| R0723 | DB05170 | investigational | small molecule | Benzimate | Therapeutic strategy associated | Details |
| R0724 | DB05177 | investigational | small molecule | DG051 | Indication associated | Details |
| R0725 | DB05183 | investigational | small molecule | MLN0415 | Therapeutic strategy associated | Details |
| R0726 | DB05186 | investigational | small molecule | SQ-109 | Indication associated | Details |
| R0727 | DB05188 | investigational | small molecule | KD3010 | Target associated | Details |
| R0728 | DB05189 | investigational | small molecule | EPC2407 | Therapeutic strategy associated | Details |
| R0729 | DB05192 | investigational | small molecule | MB07811 | Target associated | Details |
| R0730 | DB05194 | investigational | small molecule | KB002 | Therapeutic strategy associated | Details |
| R0731 | DB05198 | investigational | small molecule | CYC116 | Therapeutic strategy associated | Details |
| R0732 | DB05199 | investigational | small molecule | LX1031 | Indication associated | Details |
| R0733 | DB05201 | investigational | small molecule | V24343 | Therapeutic strategy associated | Details |
| R0734 | DB05202 | investigational | biotech | Egaptivon pegol | Target associated | Details |
| R0735 | DB05203 | investigational | small molecule | SPP1148 | Indication associated | Details |
| R0736 | DB05204 | investigational | small molecule | XL418 | Therapeutic strategy associated | Details |
| R0737 | DB05205 | investigational | small molecule | CX157 | Indication associated | Details |
| R0738 | DB05207 | investigational | small molecule | SD118 | Target associated | Details |
| R0739 | DB05212 | investigational | small molecule | HE3286 | Therapeutic strategy associated | Details |
| R0740 | DB05218 | investigational | biotech | PN0621 | Target associated | Details |
| R0741 | DB05219 | approved; investigational | small molecule | Crisaborole | Therapeutic strategy associated | Details |
| R0742 | DB05222 | investigational | biotech | KB001 | Therapeutic strategy associated | Details |
| R0743 | DB05223 | investigational | small molecule | Pracinostat | Therapeutic strategy associated | Details |
| R0744 | DB05224 | investigational | small molecule | REP8839 | Indication associated | Details |
| R0745 | DB05227 | investigational | small molecule | APD791 | Therapeutic strategy associated | Details |
| R0746 | DB05229 | investigational | small molecule | Beraprost | Indication associated | Details |
| R0747 | DB05230 | investigational | small molecule | AC3056 | Indication associated | Details |
| R0748 | DB05234 | investigational | small molecule | LGD2941 | Indication associated | Details |
| R0749 | DB05235 | investigational | small molecule | NRP409 | Indication associated | Details |
| R0750 | DB05236 | investigational | biotech | ReN001 | Indication associated | Details |
| R0751 | DB05241 | investigational | small molecule | XL765 | Therapeutic strategy associated | Details |
| R0752 | DB05244 | investigational | small molecule | G4544 | Indication associated | Details |
| R0753 | DB05255 | investigational | small molecule | Ronacaleret | Indication associated | Details |
| R0754 | DB05259 | approved; investigational | biotech | Glatiramer | Therapeutic strategy associated | Details |
| R0755 | DB05260 | approved; investigational | small molecule | Gallium nitrate | Therapeutic strategy associated | Details |
| R0756 | DB05262 | investigational | small molecule | Oxypurinol | Indication associated | Details |
| R0757 | DB05266 | investigational | small molecule | Ibudilast | Therapeutic strategy associated | Details |
| R0758 | DB05273 | approved; investigational | small molecule | Samarium (153Sm) lexidronam | Indication associated | Details |
| R0759 | DB05282 | investigational | small molecule | MCC | Therapeutic strategy associated | Details |
| R0760 | DB05295 | investigational | small molecule | Eldecalcitol | Indication associated | Details |
| R0761 | DB05297 | investigational | small molecule | Paclitaxel docosahexaenoic acid | Therapeutic strategy associated | Details |
| R0762 | DB05300 | investigational | small molecule | PTI-801 | Indication associated | Details |
| R0763 | DB05301 | investigational | small molecule | LAX-101 | Target associated | Details |
| R0764 | DB05303 | investigational | small molecule | OMS-103HP | Target associated | Details |
| R0765 | DB05305 | investigational | biotech | Cintredekin besudotox | Therapeutic strategy associated | Details |
| R0766 | DB05309 | investigational | small molecule | TP-508 | Indication associated | Details |
| R0767 | DB05311 | approved; investigational | biotech | Ecallantide | Therapeutic strategy associated | Details |
| R0768 | DB05312 | investigational | small molecule | NVS antibody | Indication associated | Details |
| R0769 | DB05317 | investigational | small molecule | TAK-475 | Target associated | Details |
| R0770 | DB05319 | investigational | biotech | Oportuzumab monatox | Therapeutic strategy associated | Details |
| R0771 | DB05321 | investigational | biotech | PEG-uricase | Indication associated | Details |
| R0772 | DB05326 | investigational | small molecule | INKP-102 | Indication associated | Details |
| R0773 | DB05336 | approved | biotech | Obiltoxaximab | Indication associated | Details |
| R0774 | DB05339 | investigational | small molecule | MN-305 | Indication associated | Details |
| R0775 | DB05340 | investigational | small molecule | ATL-2502 | Therapeutic strategy associated | Details |
| R0776 | DB05346 | investigational | small molecule | WL-1002 | Indication associated | Details |
| R0777 | DB05367 | investigational | small molecule | Actelion-1 | Indication associated | Details |
| R0778 | DB05383 | investigational | small molecule | Pimagedine | Indication associated | Details |
| R0779 | DB05387 | investigational | small molecule | AE-941 | Therapeutic strategy associated | Details |
| R0780 | DB05389 | approved; investigational | small molecule | Tetrachlorodecaoxide | Therapeutic strategy associated | Details |
| R0781 | DB05391 | investigational | small molecule | liposomal prostaglandin E1 | Target associated | Details |
| R0782 | DB05395 | investigational | small molecule | Amibegron | Indication associated | Details |
| R0783 | DB05399 | investigational | small molecule | Succinobucol | Therapeutic strategy associated | Details |
| R0784 | DB05407 | investigational | small molecule | TBC-3711 | Indication associated | Details |
| R0785 | DB05409 | investigational | small molecule | NCX 701 | Therapeutic strategy associated | Details |
| R0786 | DB05410 | investigational | small molecule | NCX 1022 | Therapeutic strategy associated | Details |
| R0787 | DB05412 | investigational | small molecule | Talmapimod | Therapeutic strategy associated | Details |
| R0788 | DB05415 | investigational | small molecule | OSI-461 | Therapeutic strategy associated | Details |
| R0789 | DB05416 | investigational | small molecule | Cardarine | Target associated | Details |
| R0790 | DB05418 | investigational | small molecule | GW 597599 | Indication associated | Details |
| R0791 | DB05421 | investigational | small molecule | CP-122721 | Indication associated | Details |
| R0792 | DB05422 | investigational | small molecule | OPC-14523 | Indication associated | Details |
| R0793 | DB05423 | investigational | small molecule | ORG-34517 | Indication associated | Details |
| R0794 | DB05426 | investigational | biotech | Talactoferrin alfa | Therapeutic strategy associated | Details |
| R0795 | DB05428 | investigational | small molecule | Motexafin gadolinium | Therapeutic strategy associated | Details |
| R0796 | DB05431 | investigational | small molecule | MLN-977 | Therapeutic strategy associated | Details |
| R0797 | DB05432 | investigational | small molecule | DAS-431 IV | Indication associated | Details |
| R0798 | DB05433 | investigational | small molecule | rGLP-1 | Therapeutic strategy associated | Details |
| R0799 | DB05443 | investigational | small molecule | ADL 10-0101 | Indication associated | Details |
| R0800 | DB05444 | investigational | small molecule | Iroxanadine | Indication associated | Details |