Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
Search for:
Hypertension170 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0064 | DB00177 | approved; investigational | small molecule | Valsartan | Therapeutic strategy associated | Details |
| R0065 | DB00178 | approved | small molecule | Ramipril | Therapeutic strategy associated | Details |
| R0072 | DB00195 | approved; investigational | small molecule | Betaxolol | Indication associated | Details |
| R0075 | DB00203 | approved; investigational | small molecule | Sildenafil | Indication associated | Details |
| R0077 | DB00206 | approved; investigational | small molecule | Reserpine | Therapeutic strategy associated | Details |
| R0080 | DB00212 | experimental | small molecule | Remikiren | Indication associated | Details |
| R0084 | DB00217 | approved | small molecule | Bethanidine | Therapeutic strategy associated | Details |
| R0087 | DB00226 | approved | small molecule | Guanadrel | Indication associated | Details |
| R0090 | DB00232 | withdrawn | small molecule | Methyclothiazide | Therapeutic strategy associated | Details |
| R0098 | DB00264 | approved; investigational | small molecule | Metoprolol | Therapeutic strategy associated | Details |
| R0099 | DB00270 | approved; investigational | small molecule | Isradipine | Indication associated | Details |
| R0106 | DB00287 | approved | small molecule | Travoprost | Indication associated | Details |
| R0111 | DB00310 | approved | small molecule | Chlorthalidone | Therapeutic strategy associated | Details |
| R0120 | DB00335 | approved | small molecule | Atenolol | Therapeutic strategy associated | Details |
| R0123 | DB00343 | approved; investigational | small molecule | Diltiazem | Therapeutic strategy associated | Details |
| R0126 | DB00350 | approved; investigational | small molecule | Minoxidil | Therapeutic strategy associated | Details |
| R0133 | DB00373 | approved | small molecule | Timolol | Indication associated | Details |
| R0134 | DB00374 | approved; investigational | small molecule | Treprostinil | Therapeutic strategy associated | Details |
| R0137 | DB00381 | approved | small molecule | Amlodipine | Therapeutic strategy associated | Details |
| R0138 | DB00384 | approved | small molecule | Triamterene | Therapeutic strategy associated | Details |
| R0142 | DB00401 | approved | small molecule | Nisoldipine | Indication associated | Details |
| R0145 | DB00436 | approved | small molecule | Bendroflumethiazide | Therapeutic strategy associated | Details |
| R0152 | DB00457 | approved | small molecule | Prazosin | Indication associated | Details |
| R0164 | DB00481 | approved; investigational | small molecule | Raloxifene | Therapeutic strategy associated | Details |
| R0166 | DB00484 | approved | small molecule | Brimonidine | Therapeutic strategy associated | Details |
| R0170 | DB00492 | approved | small molecule | Fosinopril | Indication associated | Details |
| R0175 | DB00519 | approved | small molecule | Trandolapril | Indication associated | Details |
| R0176 | DB00521 | approved | small molecule | Carteolol | Indication associated | Details |
| R0177 | DB00524 | approved | small molecule | Metolazone | Therapeutic strategy associated | Details |
| R0178 | DB00528 | approved; investigational | small molecule | Lercanidipine | Indication associated | Details |
| R0184 | DB00542 | approved; investigational | small molecule | Benazepril | Indication associated | Details |
| R0191 | DB00559 | approved; investigational | small molecule | Bosentan | Indication associated | Details |
| R0193 | DB00562 | approved | small molecule | Benzthiazide | Therapeutic strategy associated | Details |
| R0196 | DB00571 | approved; investigational | small molecule | Propranolol | Therapeutic strategy associated | Details |
| R0199 | DB00575 | approved | small molecule | Clonidine | Indication associated | Details |
| R0201 | DB00584 | approved; vet_approved | small molecule | Enalapril | Therapeutic strategy associated | Details |
| R0204 | DB00590 | approved | small molecule | Doxazosin | Therapeutic strategy associated | Details |
| R0206 | DB00594 | approved | small molecule | Amiloride | Therapeutic strategy associated | Details |
| R0209 | DB00598 | approved | small molecule | Labetalol | Therapeutic strategy associated | Details |
| R0213 | DB00606 | approved | small molecule | Cyclothiazide | Indication associated | Details |
| R0215 | DB00612 | approved | small molecule | Bisoprolol | Indication associated | Details |
| R0221 | DB00622 | approved; investigational | small molecule | Nicardipine | Indication associated | Details |
| R0229 | DB00654 | approved; investigational | small molecule | Latanoprost | Indication associated | Details |
| R0230 | DB00657 | approved; investigational | small molecule | Mecamylamine | Therapeutic strategy associated | Details |
| R0231 | DB00661 | approved | small molecule | Verapamil | Therapeutic strategy associated | Details |
| R0240 | DB00691 | approved | small molecule | Moexipril | Indication associated | Details |
| R0241 | DB00692 | approved | small molecule | Phentolamine | Indication associated | Details |
| R0244 | DB00695 | approved; vet_approved | small molecule | Furosemide | Indication associated | Details |
| R0256 | DB00727 | approved; investigational | small molecule | Nitroglycerin | Indication associated | Details |
| R0259 | DB00738 | approved; investigational | small molecule | Pentamidine | Indication associated | Details |
| R0276 | DB00774 | approved; investigational; withdrawn | small molecule | Hydroflumethiazide | Indication associated | Details |
| R0280 | DB00785 | approved | small molecule | Cryptenamine | Therapeutic strategy associated | Details |
| R0283 | DB00796 | approved | small molecule | Candesartan cilexetil | Target associated | Details |
| R0284 | DB00800 | approved | small molecule | Fenoldopam | Indication associated | Details |
| R0288 | DB00808 | approved | small molecule | Indapamide | Therapeutic strategy associated | Details |
| R0293 | DB00820 | approved; investigational | small molecule | Tadalafil | Therapeutic strategy associated | Details |
| R0314 | DB00866 | experimental; withdrawn | small molecule | Alprenolol | Indication associated | Details |
| R0315 | DB00869 | approved | small molecule | Dorzolamide | Indication associated | Details |
| R0320 | DB00876 | approved | small molecule | Eprosartan | Target associated | Details |
| R0321 | DB00880 | approved; vet_approved | small molecule | Chlorothiazide | Therapeutic strategy associated | Details |
| R0322 | DB00881 | approved; investigational | small molecule | Quinapril | Indication associated | Details |
| R0326 | DB00886 | investigational | small molecule | Omapatrilat | Indication associated | Details |
| R0329 | DB00905 | approved; investigational | small molecule | Bimatoprost | Indication associated | Details |
| R0335 | DB00925 | approved | small molecule | Phenoxybenzamine | Indication associated | Details |
| R0339 | DB00937 | approved; illicit | small molecule | Diethylpropion | Indication associated | Details |
| R0346 | DB00960 | approved; investigational | small molecule | Pindolol | Indication associated | Details |
| R0348 | DB00968 | approved | small molecule | Methyldopa | Therapeutic strategy associated | Details |
| R0361 | DB00999 | approved; vet_approved | small molecule | Hydrochlorothiazide | Indication associated | Details |
| R0374 | DB01021 | approved; vet_approved | small molecule | Trichlormethiazide | Therapeutic strategy associated | Details |
| R0375 | DB01023 | approved; investigational | small molecule | Felodipine | Indication associated | Details |
| R0377 | DB01029 | approved; investigational | small molecule | Irbesartan | Target associated | Details |
| R0387 | DB01054 | approved; investigational | small molecule | Nitrendipine | Indication associated | Details |
| R0396 | DB01088 | approved; investigational | small molecule | Iloprost | Therapeutic strategy associated | Details |
| R0397 | DB01089 | approved | small molecule | Deserpidine | Therapeutic strategy associated | Details |
| R0398 | DB01090 | approved | small molecule | Pentolinium | Therapeutic strategy associated | Details |
| R0410 | DB01115 | approved | small molecule | Nifedipine | Indication associated | Details |
| R0411 | DB01116 | approved; investigational | small molecule | Trimethaphan | Therapeutic strategy associated | Details |
| R0420 | DB01136 | approved; investigational | small molecule | Carvedilol | Indication associated | Details |
| R0429 | DB01156 | approved | small molecule | Bupropion | Indication associated | Details |
| R0431 | DB01162 | approved | small molecule | Terazosin | Therapeutic strategy associated | Details |
| R0433 | DB01170 | approved | small molecule | Guanethidine | Indication associated | Details |
| R0435 | DB01180 | approved | small molecule | Rescinnamine | Indication associated | Details |
| R0440 | DB01193 | approved; investigational | small molecule | Acebutolol | Indication associated | Details |
| R0441 | DB01194 | approved | small molecule | Brinzolamide | Indication associated | Details |
| R0444 | DB01197 | approved | small molecule | Captopril | Indication associated | Details |
| R0446 | DB01203 | approved | small molecule | Nadolol | Indication associated | Details |
| R0449 | DB01210 | approved | small molecule | Levobunolol | Indication associated | Details |
| R0451 | DB01214 | approved | small molecule | Metipranolol | Indication associated | Details |
| R0461 | DB01240 | approved | small molecule | Epoprostenol | Therapeutic strategy associated | Details |
| R0463 | DB01244 | approved; withdrawn | small molecule | Bepridil | Therapeutic strategy associated | Details |
| R0474 | DB01275 | approved | small molecule | Hydralazine | Indication associated | Details |
| R0482 | DB01295 | experimental | small molecule | Bevantolol | Indication associated | Details |
| R0491 | DB01325 | approved | small molecule | Quinethazone | Therapeutic strategy associated | Details |
| R0496 | DB01340 | approved | small molecule | Cilazapril | Indication associated | Details |
| R0497 | DB01342 | experimental | small molecule | Forasartan | Target associated | Details |
| R0498 | DB01347 | experimental | small molecule | Saprisartan | Target associated | Details |
| R0499 | DB01348 | approved | small molecule | Spirapril | Indication associated | Details |
| R0500 | DB01349 | experimental | small molecule | Tasosartan | Target associated | Details |
| R0502 | DB01359 | approved; investigational | small molecule | Penbutolol | Indication associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |