Investigational Drugs
Investigational drugs for NAFLD are derived from global clinical trials with the latest progress, and detailed drug properties are extracted from DrugBank and PubChem. For each drug, related therapeutic strategies, targets, and clinical trials in NAFLDkb are presented with knowledge graphs.
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581 records.
| Drug ID | Drug Name | Type | DrugBank ID | Targets | Category | Latest Progress | |
|---|---|---|---|---|---|---|---|
| D103 | Deferasirox | Chemical drug | DB01609 | -- | Chelating agent | Under clinical trials | Details |
| D104 | Delta-tocotrienol | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D105 | DHA | Chemical drug | DB03756 | PPARA ligand; PPARG ligand | Anti-inflammatory | Under clinical trials | Details |
| D106 | DHA-EE | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D107 | Diacerein | Chemical drug | DB11994 | ALOX5 inhibitor | Antiarthritic drug; antiinflammatory agent | Under clinical trials | Details |
| D108 | Diamel | Chemical drug | DB00672 | -- | -- | Under clinical trials | Details |
| D109 | Diammonium glycyrrhizate | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D110 | Diane-35 | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D111 | Digestive enzymes | Supplement | -- | -- | -- | Under clinical trials | Details |
| D112 | Digoxin | Chemical drug | DB00390 | ATP1A1 inhibitor; ATP1A2 inhibitor; ATP1A3 inhibitor; ATP1A4 inhibitor | Antiarrhythmic | Under clinical trials | Details |
| D113 | Dihydromyricetin | Chemical drug | DB15645 | -- | -- | Under clinical trials | Details |
| D114 | Doxycycline | Chemical drug | DB00254 | -- | -- | Under clinical trials | Details |
| D115 | DS102 | Miscellany | -- | -- | -- | Under clinical trials | Details |
| D116 | Dulaglutide | Biological drug | DB09045 | GLP1R agonist | Improve insulin resistance | Under clinical trials | Details |
| D117 | EDP-305 | Chemical drug | -- | FXR agonist | Enhance lipid metabolism | Under clinical trials | Details |
| D118 | Efamax | Miscellany | -- | -- | Antimycobacterial drug | Under clinical trials | Details |
| D119 | Elafibranor | Chemical drug | DB05187 | PPARA; PPARD; PPARG | Anti-inflammatory | Failed in clinical trials | Details |
| D120 | Elobixibat | Chemical drug | DB12486 | SLC10A1 inhibitor | Gastrointestinal drug | Under clinical trials | Details |
| D121 | Embryonic Bovine Liver Extract Tablets | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D122 | Empagliflozin | Chemical drug | DB09038 | SLC5A2 inhibitor; SGLT-2 inhibitor | Improve insulin resistance | Under clinical trials | Details |
| D123 | Emricasan | Chemical drug | DB05408 | caspase inhibitor | Anti-inflammatory | Failed in clinical trials | Details |
| D124 | EPA-E | Chemical drug | -- | DGAT1 inhibitor; PLA2 inhibitor | Antiinflammatory agent; Neuroprotective drug | Failed in clinical trials | Details |
| D125 | Epanova | Chemical drug | DB11133 | PPARG ligand; PPARA activator | Enhance lipid metabolism | Under clinical trials | Details |
| D126 | Ergocalciferol | Supplement | DB00153 | VDR agonist; VDR modulator | Calcium regulator; Vitamin source drug | Under clinical trials | Details |
| D127 | Eubacterium hallii | Supplement | -- | -- | -- | Under clinical trials | Details |
| D128 | Evogliptin | Chemical drug | DB12625 | DPP4 inhibitor | -- | Under clinical trials | Details |
| D129 | Exenatide | Biological drug | DB01276 | GLP1R activator; GLP1R agonist | Improve insulin resistance | Under clinical trials | Details |
| D130 | EYP001a | Chemical drug | -- | FXR agonist;FXR modulator | Enhance lipid metabolism | Under clinical trials | Details |
| D131 | Ezetimibe | Chemical drug | DB00973 | SOAT1 inhibitor; | Enhance lipid metabolism | Under clinical trials | Details |
| D132 | Femarelle | Biological extract | -- | -- | Immunomodulator | Under clinical trials | Details |
| D133 | Fenofibrate | Chemical drug | DB01039 | PPARA agonist; NR1I2 partial agonist | Anti-inflammatory | Under clinical trials | Details |
| D134 | Fenretinide | Chemical drug | DB05076 | RARB agonist; RARG agonist | Anti-fibrosis | Under clinical trials | Details |
| D135 | Fenugreek | Biological extract | -- | -- | -- | Under clinical trials | Details |
| D136 | Firsocostat | Chemical drug | DB16166 | ACC inhibitor | Enhance lipid metabolism | Under clinical trials | Details |
| D137 | Fish oil | Biological drug | DB13961 | -- | -- | Under clinical trials | Details |
| D138 | Flaxseed | Biological drug | DB10708 | -- | Anti-inflammatory; Antioxidant; Antineoplastic drug | Under clinical trials | Details |
| D139 | Fluconazole | Chemical drug | DB00196 | CYP51A1 inhibitor | Antifungal | Under clinical trials | Details |
| D140 | Folic acid | Supplement | DB00158 | FOLR2 binder | -- | Under clinical trials | Details |
| D141 | Foralumab | Biological drug | DB16170 | -- | -- | Under clinical trials | Details |
| D142 | Fructose | Chemical drug | DB04173 | -- | Intravenous nutrition drug | Under clinical trials | Details |
| D143 | FT-4101 | Miscellany | -- | FASN inhibitor | Enhance lipid metabolism | Under clinical trials | Details |
| D144 | FTZ | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D145 | Fucoidan | Chemical drug | -- | -- | -- | Under clinical trials | Details |
| D146 | FucoVital | Supplement | -- | -- | -- | Under clinical trials | Details |
| D147 | Garlic | Biological drug | DB10532 | -- | -- | Under clinical trials | Details |
| D148 | GB1211 | Chemical drug | -- | Gelactin-3 inhibitor | Anti-fibrosis | Under clinical trials | Details |
| D149 | Gemcabene | Chemical drug | DB05123 | ACC inhibitor; apo C-III inhibitor; CRP inhibitor; CCR2 receptor antagonist; CCR5 receptor antagonist; lipoprotein A inhibitor; PPAR agonist; sulfatase inhibitor | Enhance lipid metabolism; Anti-fibrosis | Failed in clinical trials | Details |
| D150 | Genistein | Chemical drug | DB01645 | NCOA1; NCOA2; NR1I2 | -- | Under clinical trials | Details |
| D151 | Ginger | Herbal medicine | DB10344 | -- | Antiallergic drug | Under clinical trials | Details |
| D152 | Ginseng | Herbal medicine | DB01404 | AHR agonist | -- | Under clinical trials | Details |