Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0401 | DB01094 | experimental | small molecule | Hesperetin | Therapeutic strategy associated | Details |
| R0402 | DB01095 | approved | small molecule | Fluvastatin | Target associated | Details |
| R0403 | DB01097 | approved; investigational | small molecule | Leflunomide | Therapeutic strategy associated | Details |
| R0404 | DB01103 | investigational | small molecule | Quinacrine | Therapeutic strategy associated | Details |
| R0405 | DB01104 | approved | small molecule | Sertraline | Indication associated | Details |
| R0406 | DB01109 | approved; investigational | small molecule | Heparin | Target associated | Details |
| R0407 | DB01110 | approved; investigational; vet_approved | small molecule | Miconazole | Therapeutic strategy associated | Details |
| R0408 | DB01111 | approved; vet_approved | small molecule | Colistimethate | Therapeutic strategy associated | Details |
| R0409 | DB01112 | approved | small molecule | Cefuroxime | Indication associated | Details |
| R0410 | DB01115 | approved | small molecule | Nifedipine | Indication associated | Details |
| R0411 | DB01116 | approved; investigational | small molecule | Trimethaphan | Therapeutic strategy associated | Details |
| R0412 | DB01117 | approved | small molecule | Atovaquone | Indication associated | Details |
| R0413 | DB01118 | approved; investigational | small molecule | Amiodarone | Target associated | Details |
| R0414 | DB01119 | approved | small molecule | Diazoxide | Indication associated | Details |
| R0415 | DB01124 | approved; investigational | small molecule | Tolbutamide | Indication associated | Details |
| R0416 | DB01125 | approved | small molecule | Anisindione | Indication associated | Details |
| R0417 | DB01126 | approved; investigational | small molecule | Dutasteride | Therapeutic strategy associated | Details |
| R0418 | DB01130 | approved; investigational | small molecule | Prednicarbate | Therapeutic strategy associated | Details |
| R0419 | DB01134 | experimental; vet_approved | small molecule | Desoxycorticosterone pivalate | Indication associated | Details |
| R0420 | DB01136 | approved; investigational | small molecule | Carvedilol | Indication associated | Details |
| R0421 | DB01138 | approved | small molecule | Sulfinpyrazone | Therapeutic strategy associated | Details |
| R0422 | DB01140 | approved; vet_approved; withdrawn | small molecule | Cefadroxil | Indication associated | Details |
| R0423 | DB01142 | approved; investigational | small molecule | Doxepin | Indication associated | Details |
| R0424 | DB01143 | approved; investigational | small molecule | Amifostine | Therapeutic strategy associated | Details |
| R0425 | DB01149 | approved; withdrawn | small molecule | Nefazodone | Indication associated | Details |
| R0426 | DB01150 | approved | small molecule | Cefprozil | Indication associated | Details |
| R0427 | DB01151 | approved; investigational | small molecule | Desipramine | Indication associated | Details |
| R0428 | DB01155 | approved; investigational | small molecule | Gemifloxacin | Indication associated | Details |
| R0429 | DB01156 | approved | small molecule | Bupropion | Indication associated | Details |
| R0430 | DB01157 | approved; investigational | small molecule | Trimetrexate | Indication associated | Details |
| R0431 | DB01162 | approved | small molecule | Terazosin | Therapeutic strategy associated | Details |
| R0432 | DB01169 | approved; investigational | small molecule | Arsenic trioxide | Therapeutic strategy associated | Details |
| R0433 | DB01170 | approved | small molecule | Guanethidine | Indication associated | Details |
| R0434 | DB01172 | approved; investigational; vet_approved | small molecule | Kanamycin | Indication associated | Details |
| R0435 | DB01180 | approved | small molecule | Rescinnamine | Indication associated | Details |
| R0436 | DB01182 | approved | small molecule | Propafenone | Indication associated | Details |
| R0437 | DB01183 | approved; vet_approved | small molecule | Naloxone | Target associated | Details |
| R0438 | DB01188 | approved; investigational | small molecule | Ciclopirox | Therapeutic strategy associated | Details |
| R0439 | DB01191 | approved; illicit; investigational; withdrawn | small molecule | Dexfenfluramine | Therapeutic strategy associated | Details |
| R0440 | DB01193 | approved; investigational | small molecule | Acebutolol | Indication associated | Details |
| R0441 | DB01194 | approved | small molecule | Brinzolamide | Indication associated | Details |
| R0442 | DB01195 | approved; withdrawn | small molecule | Flecainide | Indication associated | Details |
| R0443 | DB01196 | approved; investigational | small molecule | Estramustine | Therapeutic strategy associated | Details |
| R0444 | DB01197 | approved | small molecule | Captopril | Indication associated | Details |
| R0445 | DB01200 | approved; investigational | small molecule | Bromocriptine | Therapeutic strategy associated | Details |
| R0446 | DB01203 | approved | small molecule | Nadolol | Indication associated | Details |
| R0447 | DB01207 | experimental | small molecule | Ridogrel | Indication associated | Details |
| R0448 | DB01208 | approved; investigational; withdrawn | small molecule | Sparfloxacin | Indication associated | Details |
| R0449 | DB01210 | approved | small molecule | Levobunolol | Indication associated | Details |
| R0450 | DB01212 | approved | small molecule | Ceftriaxone | Indication associated | Details |
| R0451 | DB01214 | approved | small molecule | Metipranolol | Indication associated | Details |
| R0452 | DB01221 | approved; vet_approved | small molecule | Ketamine | Indication associated | Details |
| R0453 | DB01222 | approved | small molecule | Budesonide | Therapeutic strategy associated | Details |
| R0454 | DB01223 | approved | small molecule | Aminophylline | Therapeutic strategy associated | Details |
| R0455 | DB01224 | approved | small molecule | Quetiapine | Indication associated | Details |
| R0456 | DB01225 | approved | small molecule | Enoxaparin | Indication associated | Details |
| R0457 | DB01228 | approved; investigational; withdrawn | small molecule | Encainide | Indication associated | Details |
| R0458 | DB01229 | approved; vet_approved | small molecule | Paclitaxel | Therapeutic strategy associated | Details |
| R0459 | DB01233 | approved; investigational | small molecule | Metoclopramide | Indication associated | Details |
| R0460 | DB01234 | approved; investigational; vet_approved | small molecule | Dexamethasone | Therapeutic strategy associated | Details |
| R0461 | DB01240 | approved | small molecule | Epoprostenol | Therapeutic strategy associated | Details |
| R0462 | DB01242 | approved; investigational; vet_approved | small molecule | Clomipramine | Indication associated | Details |
| R0463 | DB01244 | approved; withdrawn | small molecule | Bepridil | Therapeutic strategy associated | Details |
| R0464 | DB01247 | approved | small molecule | Isocarboxazid | Indication associated | Details |
| R0465 | DB01248 | approved; investigational | small molecule | Docetaxel | Therapeutic strategy associated | Details |
| R0466 | DB01250 | approved | small molecule | Olsalazine | Therapeutic strategy associated | Details |
| R0467 | DB01251 | approved; investigational | small molecule | Gliquidone | Indication associated | Details |
| R0468 | DB01252 | investigational | small molecule | Mitiglinide | Target associated | Details |
| R0469 | DB01255 | approved; investigational | small molecule | Lisdexamfetamine | Indication associated | Details |
| R0470 | DB01260 | approved; investigational | small molecule | Desonide | Therapeutic strategy associated | Details |
| R0471 | DB01269 | approved; investigational | biotech | Panitumumab | Therapeutic strategy associated | Details |
| R0472 | DB01270 | approved | biotech | Ranibizumab | Indication associated | Details |
| R0473 | DB01274 | approved; investigational | small molecule | Arformoterol | Therapeutic strategy associated | Details |
| R0474 | DB01275 | approved | small molecule | Hydralazine | Indication associated | Details |
| R0475 | DB01277 | approved; investigational | biotech | Mecasermin | Indication associated | Details |
| R0476 | DB01278 | approved; investigational | small molecule | Pramlintide | Therapeutic strategy associated | Details |
| R0477 | DB01280 | approved; investigational | small molecule | Nelarabine | Therapeutic strategy associated | Details |
| R0478 | DB01281 | approved | biotech | Abatacept | Indication associated | Details |
| R0479 | DB01283 | approved; investigational | small molecule | Lumiracoxib | Indication associated | Details |
| R0480 | DB01289 | investigational | small molecule | Glisoxepide | Indication associated | Details |
| R0481 | DB01294 | approved; vet_approved | small molecule | Bismuth subsalicylate | Therapeutic strategy associated | Details |
| R0482 | DB01295 | experimental | small molecule | Bevantolol | Indication associated | Details |
| R0483 | DB01296 | approved; investigational | small molecule | Glucosamine | Indication associated | Details |
| R0484 | DB01303 | approved | small molecule | Oxtriphylline | Therapeutic strategy associated | Details |
| R0485 | DB01306 | approved | biotech | Insulin aspart | Indication associated | Details |
| R0486 | DB01307 | approved | biotech | Insulin detemir | Indication associated | Details |
| R0487 | DB01309 | approved | biotech | Insulin glulisine | Indication associated | Details |
| R0488 | DB01319 | approved | small molecule | Fosamprenavir | Therapeutic strategy associated | Details |
| R0489 | DB01321 | investigational | small molecule | Josamycin | Indication associated | Details |
| R0490 | DB01324 | approved | small molecule | Polythiazide | Therapeutic strategy associated | Details |
| R0491 | DB01325 | approved | small molecule | Quinethazone | Therapeutic strategy associated | Details |
| R0492 | DB01327 | approved | small molecule | Cefazolin | Indication associated | Details |
| R0493 | DB01328 | approved; investigational | small molecule | Cefonicid | Indication associated | Details |
| R0494 | DB01329 | approved; investigational | small molecule | Cefoperazone | Indication associated | Details |
| R0495 | DB01330 | approved | small molecule | Cefotetan | Indication associated | Details |
| R0496 | DB01340 | approved | small molecule | Cilazapril | Indication associated | Details |
| R0497 | DB01342 | experimental | small molecule | Forasartan | Target associated | Details |
| R0498 | DB01347 | experimental | small molecule | Saprisartan | Target associated | Details |
| R0499 | DB01348 | approved | small molecule | Spirapril | Indication associated | Details |
| R0500 | DB01349 | experimental | small molecule | Tasosartan | Target associated | Details |