Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
Search for:
inflammatory457 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0343 | DB00950 | approved; investigational | small molecule | Fexofenadine | Therapeutic strategy associated | Details |
| R0345 | DB00959 | approved; vet_approved | small molecule | Methylprednisolone | Therapeutic strategy associated | Details |
| R0347 | DB00963 | approved | small molecule | Bromfenac | Therapeutic strategy associated | Details |
| R0356 | DB00991 | approved | small molecule | Oxaprozin | Therapeutic strategy associated | Details |
| R0357 | DB00993 | approved | small molecule | Azathioprine | Therapeutic strategy associated | Details |
| R0358 | DB00994 | approved; vet_approved | small molecule | Neomycin | Indication associated | Details |
| R0359 | DB00995 | approved; investigational | small molecule | Auranofin | Therapeutic strategy associated | Details |
| R0363 | DB01003 | approved | small molecule | Cromoglicic acid | Therapeutic strategy associated | Details |
| R0366 | DB01009 | approved; vet_approved | small molecule | Ketoprofen | Therapeutic strategy associated | Details |
| R0368 | DB01013 | approved | small molecule | Clobetasol propionate | Therapeutic strategy associated | Details |
| R0369 | DB01014 | approved; investigational | small molecule | Balsalazide | Therapeutic strategy associated | Details |
| R0372 | DB01017 | approved; investigational | small molecule | Minocycline | Target associated | Details |
| R0376 | DB01024 | approved | small molecule | Mycophenolic acid | Therapeutic strategy associated | Details |
| R0379 | DB01032 | approved; investigational | small molecule | Probenecid | Therapeutic strategy associated | Details |
| R0382 | DB01041 | approved; investigational; withdrawn | small molecule | Thalidomide | Target associated | Details |
| R0384 | DB01047 | approved; investigational | small molecule | Fluocinonide | Therapeutic strategy associated | Details |
| R0385 | DB01050 | approved | small molecule | Ibuprofen | Target associated | Details |
| R0400 | DB01093 | approved; vet_approved | small molecule | Dimethyl sulfoxide | Therapeutic strategy associated | Details |
| R0401 | DB01094 | experimental | small molecule | Hesperetin | Therapeutic strategy associated | Details |
| R0404 | DB01103 | investigational | small molecule | Quinacrine | Therapeutic strategy associated | Details |
| R0418 | DB01130 | approved; investigational | small molecule | Prednicarbate | Therapeutic strategy associated | Details |
| R0421 | DB01138 | approved | small molecule | Sulfinpyrazone | Therapeutic strategy associated | Details |
| R0438 | DB01188 | approved; investigational | small molecule | Ciclopirox | Therapeutic strategy associated | Details |
| R0453 | DB01222 | approved | small molecule | Budesonide | Therapeutic strategy associated | Details |
| R0454 | DB01223 | approved | small molecule | Aminophylline | Therapeutic strategy associated | Details |
| R0460 | DB01234 | approved; investigational; vet_approved | small molecule | Dexamethasone | Therapeutic strategy associated | Details |
| R0466 | DB01250 | approved | small molecule | Olsalazine | Therapeutic strategy associated | Details |
| R0470 | DB01260 | approved; investigational | small molecule | Desonide | Therapeutic strategy associated | Details |
| R0471 | DB01269 | approved; investigational | biotech | Panitumumab | Therapeutic strategy associated | Details |
| R0473 | DB01274 | approved; investigational | small molecule | Arformoterol | Therapeutic strategy associated | Details |
| R0479 | DB01283 | approved; investigational | small molecule | Lumiracoxib | Indication associated | Details |
| R0481 | DB01294 | approved; vet_approved | small molecule | Bismuth subsalicylate | Therapeutic strategy associated | Details |
| R0483 | DB01296 | approved; investigational | small molecule | Glucosamine | Indication associated | Details |
| R0484 | DB01303 | approved | small molecule | Oxtriphylline | Therapeutic strategy associated | Details |
| R0494 | DB01329 | approved; investigational | small molecule | Cefoperazone | Indication associated | Details |
| R0505 | DB01380 | approved; investigational | small molecule | Cortisone acetate | Therapeutic strategy associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0508 | DB01384 | experimental | small molecule | Paramethasone | Therapeutic strategy associated | Details |
| R0511 | DB01394 | approved | small molecule | Colchicine | Therapeutic strategy associated | Details |
| R0513 | DB01401 | approved | small molecule | Choline magnesium trisalicylate | Therapeutic strategy associated | Details |
| R0515 | DB01410 | approved; investigational | small molecule | Ciclesonide | Therapeutic strategy associated | Details |
| R0520 | DB01419 | approved | small molecule | Antrafenine | Therapeutic strategy associated | Details |
| R0521 | DB01424 | approved; withdrawn | small molecule | Aminophenazone | Therapeutic strategy associated | Details |
| R0539 | DB01600 | approved | small molecule | Tiaprofenic acid | Therapeutic strategy associated | Details |
| R0544 | DB01611 | approved | small molecule | Hydroxychloroquine | Therapeutic strategy associated | Details |
| R0560 | DB02266 | approved | small molecule | Flufenamic acid | Target associated | Details |
| R0561 | DB02342 | investigational | small molecule | 2-Methoxyestradiol | Indication associated | Details |
| R0590 | DB03619 | approved | small molecule | Deoxycholic acid | Therapeutic strategy associated | Details |
| R0595 | DB03849 | investigational | small molecule | Cilomilast | Therapeutic strategy associated | Details |
| R0599 | DB04335 | experimental; investigational | small molecule | Inosine | Therapeutic strategy associated | Details |
| R0600 | DB04339 | approved; investigational | small molecule | Carbocisteine | Therapeutic strategy associated | Details |
| R0606 | DB04552 | experimental | small molecule | Niflumic acid | Therapeutic strategy associated | Details |
| R0614 | DB04725 | investigational | small molecule | Licofelone | Therapeutic strategy associated | Details |
| R0615 | DB04743 | approved; investigational; withdrawn | small molecule | Nimesulide | Therapeutic strategy associated | Details |
| R0617 | DB04817 | approved; investigational; withdrawn | small molecule | Metamizole | Therapeutic strategy associated | Details |
| R0626 | DB04854 | approved | small molecule | Febuxostat | Therapeutic strategy associated | Details |
| R0636 | DB04875 | investigational | small molecule | Pralnacasan | Therapeutic strategy associated | Details |
| R0640 | DB04889 | investigational | small molecule | Bicifadine | Therapeutic strategy associated | Details |
| R0641 | DB04897 | approved; investigational | biotech | Lucinactant | Therapeutic strategy associated | Details |
| R0652 | DB04932 | approved; investigational | biotech | Defibrotide | Therapeutic strategy associated | Details |
| R0653 | DB04933 | investigational | small molecule | Eritoran | Target associated | Details |
| R0654 | DB04934 | investigational | small molecule | Rifalazil | Therapeutic strategy associated | Details |
| R0657 | DB04949 | investigational | biotech | Pexelizumab | Therapeutic strategy associated | Details |
| R0658 | DB04951 | approved; investigational | small molecule | Pirfenidone | Therapeutic strategy associated | Details |
| R0667 | DB04979 | investigational | biotech | AVR118 | Therapeutic strategy associated | Details |
| R0677 | DB05017 | investigational | small molecule | YSIL6 | Target associated | Details |
| R0680 | DB05032 | investigational | small molecule | REV131 | Therapeutic strategy associated | Details |
| R0684 | DB05048 | investigational | small molecule | Cannabinor | Therapeutic strategy associated | Details |
| R0688 | DB05054 | investigational | small molecule | AN0128 | Therapeutic strategy associated | Details |
| R0693 | DB05075 | investigational | small molecule | TG-100801 | Therapeutic strategy associated | Details |
| R0699 | DB05095 | investigational | small molecule | Cimicoxib | Therapeutic strategy associated | Details |
| R0708 | DB05122 | investigational | small molecule | R1295 | Therapeutic strategy associated | Details |
| R0711 | DB05130 | investigational | small molecule | INCB3284 | Target associated | Details |
| R0713 | DB05133 | investigational | small molecule | VP025 | Therapeutic strategy associated | Details |
| R0714 | DB05136 | investigational | biotech | Bavituximab | Therapeutic strategy associated | Details |
| R0719 | DB05157 | investigational | small molecule | KC706 | Therapeutic strategy associated | Details |
| R0720 | DB05159 | investigational | small molecule | CCX915 | Therapeutic strategy associated | Details |
| R0721 | DB05161 | investigational | small molecule | Elafin | Therapeutic strategy associated | Details |
| R0725 | DB05183 | investigational | small molecule | MLN0415 | Therapeutic strategy associated | Details |
| R0730 | DB05194 | investigational | small molecule | KB002 | Therapeutic strategy associated | Details |
| R0739 | DB05212 | investigational | small molecule | HE3286 | Therapeutic strategy associated | Details |
| R0740 | DB05218 | investigational | biotech | PN0621 | Target associated | Details |
| R0741 | DB05219 | approved; investigational | small molecule | Crisaborole | Therapeutic strategy associated | Details |
| R0754 | DB05259 | approved; investigational | biotech | Glatiramer | Therapeutic strategy associated | Details |
| R0757 | DB05266 | investigational | small molecule | Ibudilast | Therapeutic strategy associated | Details |
| R0764 | DB05303 | investigational | small molecule | OMS-103HP | Target associated | Details |
| R0767 | DB05311 | approved; investigational | biotech | Ecallantide | Therapeutic strategy associated | Details |
| R0775 | DB05340 | investigational | small molecule | ATL-2502 | Therapeutic strategy associated | Details |
| R0780 | DB05389 | approved; investigational | small molecule | Tetrachlorodecaoxide | Therapeutic strategy associated | Details |
| R0781 | DB05391 | investigational | small molecule | liposomal prostaglandin E1 | Target associated | Details |
| R0783 | DB05399 | investigational | small molecule | Succinobucol | Therapeutic strategy associated | Details |
| R0785 | DB05409 | investigational | small molecule | NCX 701 | Therapeutic strategy associated | Details |
| R0786 | DB05410 | investigational | small molecule | NCX 1022 | Therapeutic strategy associated | Details |
| R0787 | DB05412 | investigational | small molecule | Talmapimod | Therapeutic strategy associated | Details |
| R0788 | DB05415 | investigational | small molecule | OSI-461 | Therapeutic strategy associated | Details |
| R0791 | DB05421 | investigational | small molecule | CP-122721 | Indication associated | Details |
| R0796 | DB05431 | investigational | small molecule | MLN-977 | Therapeutic strategy associated | Details |
| R0799 | DB05443 | investigational | small molecule | ADL 10-0101 | Indication associated | Details |
| R0804 | DB05451 | investigational | small molecule | P54 | Therapeutic strategy associated | Details |
| R0806 | DB05459 | investigational | biotech | Briakinumab | Indication associated | Details |