Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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inflammatory457 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R1261 | DB09241 | approved; investigational | small molecule | Methylene blue | Therapeutic strategy associated | Details |
| R1278 | DB09273 | experimental | small molecule | Doxofylline | Therapeutic strategy associated | Details |
| R1283 | DB09285 | experimental | small molecule | Morniflumate | Therapeutic strategy associated | Details |
| R1285 | DB09288 | experimental | small molecule | Propacetamol | Therapeutic strategy associated | Details |
| R1289 | DB09295 | experimental | small molecule | Talniflumate | Indication associated | Details |
| R1290 | DB09301 | approved; investigational; nutraceutical | small molecule | Chondroitin sulfate | Therapeutic strategy associated | Details |
| R1304 | DB09357 | approved | small molecule | Dexpanthenol | Therapeutic strategy associated | Details |
| R1307 | DB09398 | approved | small molecule | Fluoride ion F-18 | Indication associated | Details |
| R1310 | DB09446 | approved; investigational | biotech | Safflower oil | Therapeutic strategy associated | Details |
| R1315 | DB09502 | approved; investigational | small molecule | Fludeoxyglucose (18F) | Therapeutic strategy associated | Details |
| R1317 | DB09543 | approved; vet_approved | small molecule | Methyl salicylate | Therapeutic strategy associated | Details |
| R1322 | DB10770 | approved | biotech | Foreskin fibroblast (neonatal) | Target associated | Details |
| R1325 | DB10989 | approved | biotech | Hepatitis A Vaccine | Therapeutic strategy associated | Details |
| R1326 | DB11051 | approved; investigational | biotech | Azficel-T | Therapeutic strategy associated | Details |
| R1327 | DB11068 | approved | small molecule | Selenic acid | Therapeutic strategy associated | Details |
| R1329 | DB11079 | approved | small molecule | Trolamine salicylate | Therapeutic strategy associated | Details |
| R1330 | DB11086 | approved | biotech | Cocoa butter | Therapeutic strategy associated | Details |
| R1333 | DB11100 | approved | small molecule | Allantoin | Therapeutic strategy associated | Details |
| R1337 | DB11114 | approved | biotech | Eucalyptus oil | Therapeutic strategy associated | Details |
| R1339 | DB11120 | approved; experimental | small molecule | Turpentine | Therapeutic strategy associated | Details |
| R1341 | DB11127 | approved; investigational | small molecule | Selenious acid | Therapeutic strategy associated | Details |
| R1342 | DB11131 | approved | biotech | Capsicum oleoresin | Therapeutic strategy associated | Details |
| R1343 | DB11134 | approved | small molecule | Cupric oxide | Therapeutic strategy associated | Details |
| R1344 | DB11157 | approved | small molecule | Anthralin | Therapeutic strategy associated | Details |
| R1345 | DB11160 | approved | small molecule | Phenyltoloxamine | Therapeutic strategy associated | Details |
| R1347 | DB11193 | approved | small molecule | Papain | Therapeutic strategy associated | Details |
| R1350 | DB11204 | approved | small molecule | Panthenol | Therapeutic strategy associated | Details |
| R1351 | DB11207 | approved | small molecule | Amiloxate | Therapeutic strategy associated | Details |
| R1353 | DB11218 | experimental; nutraceutical | biotech | Tea tree oil | Therapeutic strategy associated | Details |
| R1355 | DB11239 | approved | small molecule | Aluminum sulfate | Therapeutic strategy associated | Details |
| R1357 | DB11251 | approved; investigational | small molecule | Tocopherol | Therapeutic strategy associated | Details |
| R1358 | DB11254 | approved | small molecule | Hexylresorcinol | Therapeutic strategy associated | Details |
| R1360 | DB11265 | nutraceutical | biotech | Curcuma xanthorrhiza oil | Therapeutic strategy associated | Details |
| R1361 | DB11269 | approved | small molecule | Diethylamino hydroxybenzoyl hexyl benzoate | Therapeutic strategy associated | Details |
| R1362 | DB11296 | experimental | small molecule | Prezatide | Therapeutic strategy associated | Details |
| R1364 | DB11323 | approved | small molecule | Glycol salicylate | Therapeutic strategy associated | Details |
| R1365 | DB11324 | investigational | small molecule | Nonivamide | Therapeutic strategy associated | Details |
| R1366 | DB11332 | approved | small molecule | Sinapultide | Therapeutic strategy associated | Details |
| R1367 | DB11333 | approved; investigational | small molecule | Poloxamer 188 | Therapeutic strategy associated | Details |
| R1368 | DB11338 | approved; nutraceutical | biotech | Clove oil | Therapeutic strategy associated | Details |
| R1369 | DB11358 | investigational; nutraceutical | biotech | Evening primrose oil | Therapeutic strategy associated | Details |
| R1370 | DB11362 | approved | small molecule | Selexipag | Therapeutic strategy associated | Details |
| R1375 | DB11569 | approved; investigational | biotech | Ixekizumab | Therapeutic strategy associated | Details |
| R1376 | DB11580 | approved; investigational | biotech | Ravulizumab | Therapeutic strategy associated | Details |
| R1378 | DB11582 | experimental | small molecule | Thiocolchicoside | Target associated | Details |
| R1380 | DB11588 | approved; investigational | small molecule | Carbon monoxide | Therapeutic strategy associated | Details |
| R1382 | DB11601 | approved | biotech | Tuberculin purified protein derivative | Therapeutic strategy associated | Details |
| R1383 | DB11605 | approved | small molecule | Myrrh | Therapeutic strategy associated | Details |
| R1384 | DB11611 | approved | small molecule | Lifitegrast | Therapeutic strategy associated | Details |
| R1385 | DB11626 | approved | biotech | Tasonermin | Therapeutic strategy associated | Details |
| R1392 | DB11693 | approved; investigational | small molecule | Voclosporin | Therapeutic strategy associated | Details |
| R1395 | DB11714 | approved; investigational | biotech | Durvalumab | Therapeutic strategy associated | Details |
| R1400 | DB11753 | approved; investigational | small molecule | Rifamycin | Therapeutic strategy associated | Details |
| R1401 | DB11755 | investigational | small molecule | Tetrahydrocannabivarin | Therapeutic strategy associated | Details |
| R1404 | DB11776 | approved; investigational | biotech | Brodalumab | Therapeutic strategy associated | Details |
| R1408 | DB11817 | approved; investigational | small molecule | Baricitinib | Therapeutic strategy associated | Details |
| R1412 | DB11834 | approved; investigational | biotech | Guselkumab | Therapeutic strategy associated | Details |
| R1414 | DB11856 | investigational | biotech | Ligelizumab | Therapeutic strategy associated | Details |
| R1417 | DB11921 | approved; investigational | small molecule | Deflazacort | Therapeutic strategy associated | Details |
| R1422 | DB11952 | approved; investigational | small molecule | Duvelisib | Therapeutic strategy associated | Details |
| R1423 | DB11967 | approved; investigational | small molecule | Binimetinib | Therapeutic strategy associated | Details |
| R1424 | DB11976 | approved; investigational | biotech | Anifrolumab | Therapeutic strategy associated | Details |
| R1426 | DB11988 | approved; investigational | biotech | Ocrelizumab | Therapeutic strategy associated | Details |
| R1428 | DB12010 | approved; investigational | small molecule | Fostamatinib | Target associated | Details |
| R1429 | DB12023 | approved; investigational | biotech | Benralizumab | Therapeutic strategy associated | Details |
| R1430 | DB12035 | approved; investigational | small molecule | Sarecycline | Therapeutic strategy associated | Details |
| R1433 | DB12140 | investigational | small molecule | Dilmapimod | Therapeutic strategy associated | Details |
| R1435 | DB12157 | investigational | biotech | Fasinumab | Therapeutic strategy associated | Details |
| R1436 | DB12159 | approved; investigational | biotech | Dupilumab | Therapeutic strategy associated | Details |
| R1437 | DB12169 | approved; investigational | biotech | Tralokinumab | Therapeutic strategy associated | Details |
| R1440 | DB12249 | approved; investigational | biotech | Stem bromelain | Therapeutic strategy associated | Details |
| R1442 | DB12328 | approved; investigational | small molecule | Cantharidin | Therapeutic strategy associated | Details |
| R1446 | DB12371 | approved; investigational | small molecule | Siponimod | Therapeutic strategy associated | Details |
| R1450 | DB12499 | approved; investigational | small molecule | Clascoterone | Therapeutic strategy associated | Details |
| R1453 | DB12530 | approved; investigational | biotech | Inebilizumab | Therapeutic strategy associated | Details |
| R1457 | DB12598 | investigational | small molecule | Nafamostat | Therapeutic strategy associated | Details |
| R1458 | DB12651 | investigational | small molecule | Bardoxolone | Therapeutic strategy associated | Details |
| R1461 | DB12764 | investigational | small molecule | Opaganib | Therapeutic strategy associated | Details |
| R1463 | DB12808 | approved; investigational | small molecule | Trifarotene | Therapeutic strategy associated | Details |
| R1465 | DB12831 | investigational | small molecule | Gabexate | Therapeutic strategy associated | Details |
| R1467 | DB12911 | approved; investigational | small molecule | Nicoboxil | Indication associated | Details |
| R1471 | DB12965 | approved; investigational | small molecule | Silver | Therapeutic strategy associated | Details |
| R1473 | DB13037 | investigational | biotech | Namilumab | Therapeutic strategy associated | Details |
| R1476 | DB13149 | approved | biotech | Protein S human | Therapeutic strategy associated | Details |
| R1477 | DB13153 | approved; experimental | small molecule | Levomenol | Therapeutic strategy associated | Details |
| R1478 | DB13155 | approved | small molecule | Esculin | Therapeutic strategy associated | Details |
| R1479 | DB13158 | approved | small molecule | Clobetasone | Therapeutic strategy associated | Details |
| R1480 | DB13163 | approved; experimental | small molecule | Terpin hydrate | Indication associated | Details |
| R1482 | DB13167 | approved; withdrawn | small molecule | Alclofenac | Therapeutic strategy associated | Details |
| R1483 | DB13168 | nutraceutical | small molecule | Omega-6 fatty acids | Therapeutic strategy associated | Details |
| R1485 | DB13174 | experimental | small molecule | Rhein | Therapeutic strategy associated | Details |
| R1486 | DB13178 | approved; investigational; withdrawn | small molecule | Inositol | Therapeutic strategy associated | Details |
| R1490 | DB13346 | approved; withdrawn | small molecule | Bufexamac | Therapeutic strategy associated | Details |
| R1491 | DB13501 | approved; withdrawn | small molecule | Bendazac | Therapeutic strategy associated | Details |
| R1492 | DB13615 | approved; experimental | small molecule | Mifamurtide | Therapeutic strategy associated | Details |
| R1494 | DB13751 | approved; experimental | small molecule | Glycyrrhizic acid | Therapeutic strategy associated | Details |
| R1495 | DB13783 | approved; investigational | small molecule | Acemetacin | Therapeutic strategy associated | Details |
| R1496 | DB13854 | approved; investigational | small molecule | Gamolenic acid | Therapeutic strategy associated | Details |
| R1499 | DB13906 | experimental | biotech | Aloe vera leaf | Therapeutic strategy associated | Details |
| R1500 | DB13908 | approved | small molecule | Amylmetacresol | Therapeutic strategy associated | Details |