Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0801 | DB05446 | investigational | small molecule | LJP 1082 | Indication associated | Details |
| R0802 | DB05448 | investigational | small molecule | PX-12 | Therapeutic strategy associated | Details |
| R0803 | DB05449 | investigational | small molecule | FM-VP4 | Indication associated | Details |
| R0804 | DB05451 | investigational | small molecule | P54 | Therapeutic strategy associated | Details |
| R0805 | DB05456 | investigational | small molecule | ETC-588 | Indication associated | Details |
| R0806 | DB05459 | investigational | biotech | Briakinumab | Indication associated | Details |
| R0807 | DB05464 | investigational | small molecule | NOX-700 | Indication associated | Details |
| R0808 | DB05466 | investigational | small molecule | R673 | Indication associated | Details |
| R0809 | DB05470 | investigational | small molecule | VX-702 | Target associated | Details |
| R0810 | DB05474 | investigational | small molecule | T487 | Indication associated | Details |
| R0811 | DB05475 | investigational | small molecule | Golotimod | Target associated | Details |
| R0812 | DB05479 | investigational | small molecule | CZEN 002 | Therapeutic strategy associated | Details |
| R0813 | DB05484 | investigational | small molecule | MDX-018 | Therapeutic strategy associated | Details |
| R0814 | DB05485 | investigational | biotech | ADH-1 | Therapeutic strategy associated | Details |
| R0815 | DB05487 | investigational | small molecule | Custirsen | Therapeutic strategy associated | Details |
| R0816 | DB05490 | investigational | small molecule | AMG-131 | Target associated | Details |
| R0817 | DB05495 | investigational | small molecule | PG-530742 | Indication associated | Details |
| R0818 | DB05496 | investigational | biotech | Otelixizumab | Indication associated | Details |
| R0819 | DB05500 | investigational | biotech | AVN-944 | Therapeutic strategy associated | Details |
| R0820 | DB05501 | investigational | small molecule | AMD-070 | Target associated | Details |
| R0821 | DB05506 | investigational | small molecule | ISIS 113715 | Therapeutic strategy associated | Details |
| R0822 | DB05507 | investigational | small molecule | VX-765 | Therapeutic strategy associated | Details |
| R0823 | DB05511 | investigational | small molecule | Piclidenoson | Therapeutic strategy associated | Details |
| R0824 | DB05512 | investigational | biotech | MM-093 | Indication associated | Details |
| R0825 | DB05513 | investigational | small molecule | Atiprimod | Target associated | Details |
| R0826 | DB05518 | investigational | small molecule | Managlinat dialanetil | Indication associated | Details |
| R0827 | DB05519 | investigational | small molecule | Budiodarone | Indication associated | Details |
| R0828 | DB05528 | approved; investigational | small molecule | Mipomersen | Indication associated | Details |
| R0829 | DB05533 | investigational | small molecule | QR-333 | Therapeutic strategy associated | Details |
| R0830 | DB05545 | investigational | biotech | AMG 108 | Indication associated | Details |
| R0831 | DB05549 | investigational | small molecule | INO-1001 | Indication associated | Details |
| R0832 | DB05552 | investigational | small molecule | TG100-115 | Indication associated | Details |
| R0833 | DB05560 | investigational | small molecule | Delcasertib | Indication associated | Details |
| R0834 | DB05562 | investigational | small molecule | Naluzotan | Indication associated | Details |
| R0835 | DB05580 | investigational | small molecule | TRU-015 | Indication associated | Details |
| R0836 | DB05607 | investigational | small molecule | PRX-08066 | Indication associated | Details |
| R0837 | DB05616 | investigational | small molecule | 4'-Methylene-5,8,10-trideazaaminopterin | Indication associated | Details |
| R0838 | DB05631 | investigational | small molecule | ALT-2074 | Indication associated | Details |
| R0839 | DB05642 | investigational | small molecule | DDP-225 | Indication associated | Details |
| R0840 | DB05645 | investigational | small molecule | Larazotide | Indication associated | Details |
| R0841 | DB05649 | investigational | biotech | NTx-265 | Indication associated | Details |
| R0842 | DB05659 | investigational | small molecule | Faropenem medoxomil | Indication associated | Details |
| R0843 | DB05660 | investigational | small molecule | D-JNKI-1 | Therapeutic strategy associated | Details |
| R0844 | DB05667 | approved; investigational | small molecule | Levoketoconazole | Indication associated | Details |
| R0845 | DB05671 | investigational | biotech | AC-100 | Therapeutic strategy associated | Details |
| R0846 | DB05676 | approved; investigational | small molecule | Apremilast | Therapeutic strategy associated | Details |
| R0847 | DB05678 | investigational | small molecule | SLx-4090 | Indication associated | Details |
| R0848 | DB05679 | approved; investigational | biotech | Ustekinumab | Therapeutic strategy associated | Details |
| R0849 | DB05685 | investigational | biotech | FX06 | Therapeutic strategy associated | Details |
| R0850 | DB05688 | investigational | small molecule | CRx-119 | Therapeutic strategy associated | Details |
| R0851 | DB05695 | investigational | small molecule | NPS-2143 | Indication associated | Details |
| R0852 | DB05719 | investigational | small molecule | Elesclomol | Therapeutic strategy associated | Details |
| R0853 | DB05730 | investigational | small molecule | PMI-001 | Therapeutic strategy associated | Details |
| R0854 | DB05732 | investigational | small molecule | Strontium malonate | Indication associated | Details |
| R0855 | DB05735 | investigational | small molecule | Cefilavancin | Indication associated | Details |
| R0856 | DB05736 | investigational | small molecule | MIV-701 | Indication associated | Details |
| R0857 | DB05737 | investigational | small molecule | Varespladib methyl | Indication associated | Details |
| R0858 | DB05739 | investigational | biotech | CYT006-AngQb | Therapeutic strategy associated | Details |
| R0859 | DB05744 | investigational | small molecule | CRx-139 | Therapeutic strategy associated | Details |
| R0860 | DB05746 | investigational | small molecule | PF-03187207 | Indication associated | Details |
| R0861 | DB05750 | investigational | small molecule | AVE-1625 | Indication associated | Details |
| R0862 | DB05754 | investigational | small molecule | IPH 1101 | Therapeutic strategy associated | Details |
| R0863 | DB05757 | investigational | small molecule | DNB-001 | Indication associated | Details |
| R0864 | DB05758 | investigational | biotech | CYT007-TNFQb | Therapeutic strategy associated | Details |
| R0865 | DB05767 | investigational | small molecule | Andrographolide | Therapeutic strategy associated | Details |
| R0866 | DB05768 | investigational | small molecule | Alkaline Phosphatase | Therapeutic strategy associated | Details |
| R0867 | DB05769 | investigational | small molecule | LCP-AtorFen | Indication associated | Details |
| R0868 | DB05772 | investigational | small molecule | Rabeximod | Indication associated | Details |
| R0869 | DB05773 | approved; investigational | biotech | Trastuzumab emtansine | Therapeutic strategy associated | Details |
| R0870 | DB05775 | investigational | small molecule | CRx-401 | Indication associated | Details |
| R0871 | DB05777 | approved; investigational | biotech | Thrombomodulin Alfa | Therapeutic strategy associated | Details |
| R0872 | DB05787 | investigational | biotech | LM-609 | Therapeutic strategy associated | Details |
| R0873 | DB05792 | investigational | small molecule | Arylacenamide | Therapeutic strategy associated | Details |
| R0874 | DB05796 | investigational | small molecule | Daglutril | Indication associated | Details |
| R0875 | DB05804 | investigational | small molecule | Prasterone sulfate | Therapeutic strategy associated | Details |
| R0876 | DB05805 | investigational | small molecule | NS-2359 | Indication associated | Details |
| R0877 | DB05810 | investigational | small molecule | 99mTc-glucarate | Indication associated | Details |
| R0878 | DB05819 | investigational | biotech | NBI-6024 | Indication associated | Details |
| R0879 | DB05820 | investigational | small molecule | DP-b99 | Indication associated | Details |
| R0880 | DB05825 | investigational | small molecule | NCX 1015 | Therapeutic strategy associated | Details |
| R0881 | DB05829 | approved; investigational | biotech | Parathyroid hormone | Indication associated | Details |
| R0882 | DB05839 | investigational | small molecule | BG-777 | Indication associated | Details |
| R0883 | DB05840 | investigational | small molecule | AGI-1096 | Therapeutic strategy associated | Details |
| R0884 | DB05843 | investigational | small molecule | trans NV-04 | Indication associated | Details |
| R0885 | DB05849 | investigational | small molecule | NCX 950 | Therapeutic strategy associated | Details |
| R0886 | DB05854 | investigational | small molecule | CLX-0921 | Target associated | Details |
| R0887 | DB05865 | investigational | small molecule | VIT-100 | Indication associated | Details |
| R0888 | DB05866 | investigational | small molecule | ETC-1001 | Indication associated | Details |
| R0889 | DB05869 | investigational | small molecule | Ethyl pyruvate | Therapeutic strategy associated | Details |
| R0890 | DB05879 | investigational | biotech | AME-527 | Therapeutic strategy associated | Details |
| R0891 | DB05882 | investigational | small molecule | CHF 4227 | Indication associated | Details |
| R0892 | DB05888 | investigational | small molecule | MEM 1414 | Indication associated | Details |
| R0893 | DB05889 | approved; investigational | biotech | Inotuzumab ozogamicin | Therapeutic strategy associated | Details |
| R0894 | DB05892 | investigational | biotech | RI 624 | Therapeutic strategy associated | Details |
| R0895 | DB05894 | investigational | small molecule | GT 389-255 | Therapeutic strategy associated | Details |
| R0896 | DB05895 | investigational | biotech | HGS-TR2J | Therapeutic strategy associated | Details |
| R0897 | DB05905 | investigational | small molecule | TD-2749 | Indication associated | Details |
| R0898 | DB05906 | investigational | biotech | CCR5 mAb | Target associated | Details |
| R0899 | DB05911 | investigational | small molecule | RUS 3108 | Indication associated | Details |
| R0900 | DB05913 | investigational | small molecule | OSI-930 | Therapeutic strategy associated | Details |