Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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Hypertension170 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0528 | DB01556 | illicit; withdrawn | small molecule | Chlorphentermine | Therapeutic strategy associated | Details |
| R0532 | DB01580 | approved | small molecule | Oxprenolol | Indication associated | Details |
| R0548 | DB01626 | approved | small molecule | Pargyline | Therapeutic strategy associated | Details |
| R0619 | DB04831 | withdrawn | small molecule | Tienilic acid | Indication associated | Details |
| R0623 | DB04840 | approved; investigational | small molecule | Debrisoquine | Indication associated | Details |
| R0624 | DB04846 | approved; investigational | small molecule | Celiprolol | Therapeutic strategy associated | Details |
| R0629 | DB04861 | approved; investigational | small molecule | Nebivolol | Therapeutic strategy associated | Details |
| R0638 | DB04883 | investigational | small molecule | Darusentan | Indication associated | Details |
| R0689 | DB05061 | investigational | small molecule | GFT14 | Indication associated | Details |
| R0701 | DB05099 | approved; investigational | biotech | Ancrod | Therapeutic strategy associated | Details |
| R0735 | DB05203 | investigational | small molecule | SPP1148 | Indication associated | Details |
| R0746 | DB05229 | investigational | small molecule | Beraprost | Indication associated | Details |
| R0777 | DB05367 | investigational | small molecule | Actelion-1 | Indication associated | Details |
| R0784 | DB05407 | investigational | small molecule | TBC-3711 | Indication associated | Details |
| R0793 | DB05423 | investigational | small molecule | ORG-34517 | Indication associated | Details |
| R0836 | DB05607 | investigational | small molecule | PRX-08066 | Indication associated | Details |
| R0858 | DB05739 | investigational | biotech | CYT006-AngQb | Therapeutic strategy associated | Details |
| R0860 | DB05746 | investigational | small molecule | PF-03187207 | Indication associated | Details |
| R0863 | DB05757 | investigational | small molecule | DNB-001 | Indication associated | Details |
| R0874 | DB05796 | investigational | small molecule | Daglutril | Indication associated | Details |
| R0884 | DB05843 | investigational | small molecule | trans NV-04 | Indication associated | Details |
| R0944 | DB06207 | approved | small molecule | Silodosin | Therapeutic strategy associated | Details |
| R0965 | DB06267 | approved; investigational | small molecule | Udenafil | Indication associated | Details |
| R0966 | DB06268 | approved; investigational; withdrawn | small molecule | Sitaxentan | Indication associated | Details |
| R0987 | DB06345 | investigational | small molecule | AR-9281 | Therapeutic strategy associated | Details |
| R1004 | DB06403 | approved; investigational | small molecule | Ambrisentan | Indication associated | Details |
| R1056 | DB06604 | investigational | small molecule | Ilepatril | Indication associated | Details |
| R1085 | DB06709 | approved; investigational | small molecule | Methacholine | Therapeutic strategy associated | Details |
| R1086 | DB06712 | approved; investigational | small molecule | Nilvadipine | Indication associated | Details |
| R1108 | DB06826 | approved; investigational | small molecule | Unoprostone | Indication associated | Details |
| R1153 | DB08807 | experimental | small molecule | Bopindolol | Indication associated | Details |
| R1154 | DB08808 | experimental | small molecule | Bupranolol | Indication associated | Details |
| R1159 | DB08819 | approved | small molecule | Tafluprost | Indication associated | Details |
| R1161 | DB08822 | approved; investigational | small molecule | Azilsartan medoxomil | Target associated | Details |
| R1166 | DB08836 | experimental; investigational | small molecule | Temocapril | Indication associated | Details |
| R1188 | DB08931 | approved | small molecule | Riociguat | Therapeutic strategy associated | Details |
| R1189 | DB08932 | approved | small molecule | Macitentan | Indication associated | Details |
| R1195 | DB09026 | approved; investigational | small molecule | Aliskiren | Indication associated | Details |
| R1241 | DB09204 | investigational | small molecule | Arotinolol | Therapeutic strategy associated | Details |
| R1252 | DB09227 | experimental | small molecule | Barnidipine | Therapeutic strategy associated | Details |
| R1253 | DB09229 | experimental | small molecule | Aranidipine | Indication associated | Details |
| R1254 | DB09230 | investigational | small molecule | Azelnidipine | Therapeutic strategy associated | Details |
| R1255 | DB09231 | experimental | small molecule | Benidipine | Indication associated | Details |
| R1256 | DB09232 | investigational | small molecule | Cilnidipine | Indication associated | Details |
| R1257 | DB09235 | experimental | small molecule | Efonidipine | Therapeutic strategy associated | Details |
| R1258 | DB09236 | approved; investigational | small molecule | Lacidipine | Therapeutic strategy associated | Details |
| R1259 | DB09237 | approved; investigational | small molecule | Levamlodipine | Indication associated | Details |
| R1260 | DB09238 | approved; investigational | small molecule | Manidipine | Therapeutic strategy associated | Details |
| R1262 | DB09243 | experimental | small molecule | Hydracarbazine | Indication associated | Details |
| R1263 | DB09244 | experimental | small molecule | Pirlindole | Indication associated | Details |
| R1280 | DB09279 | investigational | small molecule | Fimasartan | Therapeutic strategy associated | Details |
| R1281 | DB09282 | approved; investigational | small molecule | Molsidomine | Therapeutic strategy associated | Details |
| R1303 | DB09351 | approved; investigational | small molecule | Levobetaxolol | Indication associated | Details |
| R1305 | DB09363 | investigational | small molecule | Rauwolfia serpentina root | Therapeutic strategy associated | Details |
| R1308 | DB09409 | approved | small molecule | Magnesium acetate tetrahydrate | Indication associated | Details |
| R1313 | DB09477 | approved | small molecule | Enalaprilat | Indication associated | Details |
| R1370 | DB11362 | approved | small molecule | Selexipag | Therapeutic strategy associated | Details |
| R1380 | DB11588 | approved; investigational | small molecule | Carbon monoxide | Therapeutic strategy associated | Details |
| R1389 | DB11660 | approved; investigational | small molecule | Latanoprostene bunod | Indication associated | Details |
| R1413 | DB11842 | approved; investigational | small molecule | Angiotensin II | Target associated | Details |
| R1428 | DB12010 | approved; investigational | small molecule | Fostamatinib | Target associated | Details |
| R1481 | DB13165 | experimental | small molecule | Ripasudil | Indication associated | Details |
| R1493 | DB13749 | approved; investigational | small molecule | Magnesium gluconate | Indication associated | Details |
| R1502 | DB13919 | experimental | small molecule | Candesartan | Target associated | Details |
| R1503 | DB13931 | approved | small molecule | Netarsudil | Therapeutic strategy associated | Details |
| R1544 | DB14811 | approved; investigational | biotech | Isatuximab | Therapeutic strategy associated | Details |
| R1553 | DB15044 | approved; investigational | biotech | Tafasitamab | Therapeutic strategy associated | Details |
| R1562 | DB15456 | approved; investigational | small molecule | Vericiguat | Indication associated | Details |
| R1590 | DB16165 | approved; investigational | small molecule | Finerenone | Therapeutic strategy associated | Details |
| R1608 | DB16703 | approved; investigational | small molecule | Belumosudil | Therapeutic strategy associated | Details |