Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
Search for:
apoptosis249 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0788 | DB05415 | investigational | small molecule | OSI-461 | Therapeutic strategy associated | Details |
| R0795 | DB05428 | investigational | small molecule | Motexafin gadolinium | Therapeutic strategy associated | Details |
| R0798 | DB05433 | investigational | small molecule | rGLP-1 | Therapeutic strategy associated | Details |
| R0802 | DB05448 | investigational | small molecule | PX-12 | Therapeutic strategy associated | Details |
| R0814 | DB05485 | investigational | biotech | ADH-1 | Therapeutic strategy associated | Details |
| R0815 | DB05487 | investigational | small molecule | Custirsen | Therapeutic strategy associated | Details |
| R0819 | DB05500 | investigational | biotech | AVN-944 | Therapeutic strategy associated | Details |
| R0822 | DB05507 | investigational | small molecule | VX-765 | Therapeutic strategy associated | Details |
| R0843 | DB05660 | investigational | small molecule | D-JNKI-1 | Therapeutic strategy associated | Details |
| R0852 | DB05719 | investigational | small molecule | Elesclomol | Therapeutic strategy associated | Details |
| R0869 | DB05773 | approved; investigational | biotech | Trastuzumab emtansine | Therapeutic strategy associated | Details |
| R0893 | DB05889 | approved; investigational | biotech | Inotuzumab ozogamicin | Therapeutic strategy associated | Details |
| R0896 | DB05895 | investigational | biotech | HGS-TR2J | Therapeutic strategy associated | Details |
| R0900 | DB05913 | investigational | small molecule | OSI-930 | Therapeutic strategy associated | Details |
| R0904 | DB05959 | investigational | small molecule | ENMD-1198 | Therapeutic strategy associated | Details |
| R0906 | DB05968 | investigational | small molecule | PR-104 | Therapeutic strategy associated | Details |
| R0907 | DB05969 | investigational | small molecule | SNS-032 | Therapeutic strategy associated | Details |
| R0908 | DB05971 | investigational | small molecule | Archexin | Therapeutic strategy associated | Details |
| R0915 | DB06040 | investigational | small molecule | Filanesib | Therapeutic strategy associated | Details |
| R0916 | DB06042 | investigational | small molecule | ZEN-012 | Therapeutic strategy associated | Details |
| R0917 | DB06045 | investigational | small molecule | Trofinetide | Therapeutic strategy associated | Details |
| R0919 | DB06075 | investigational | small molecule | Linsitinib | Therapeutic strategy associated | Details |
| R0920 | DB06080 | investigational | small molecule | Linifanib | Therapeutic strategy associated | Details |
| R0922 | DB06082 | investigational | small molecule | PX-478 | Therapeutic strategy associated | Details |
| R0924 | DB06094 | investigational | small molecule | Apatorsen | Therapeutic strategy associated | Details |
| R0925 | DB06097 | investigational | small molecule | GSK-923295 | Therapeutic strategy associated | Details |
| R0926 | DB06101 | investigational | biotech | IMC-1C11 | Therapeutic strategy associated | Details |
| R0929 | DB06137 | approved; investigational | small molecule | Tirbanibulin | Therapeutic strategy associated | Details |
| R0937 | DB06176 | approved; investigational | small molecule | Romidepsin | Therapeutic strategy associated | Details |
| R0939 | DB06193 | approved; investigational | small molecule | Pixantrone | Therapeutic strategy associated | Details |
| R0944 | DB06207 | approved | small molecule | Silodosin | Therapeutic strategy associated | Details |
| R0955 | DB06246 | investigational | small molecule | Exisulind | Therapeutic strategy associated | Details |
| R0960 | DB06255 | experimental | small molecule | Incadronic acid | Therapeutic strategy associated | Details |
| R0963 | DB06263 | investigational | small molecule | Amrubicin | Therapeutic strategy associated | Details |
| R0964 | DB06266 | investigational | small molecule | Lonidamine | Therapeutic strategy associated | Details |
| R0976 | DB06307 | investigational | small molecule | Apoptone | Therapeutic strategy associated | Details |
| R0979 | DB06314 | investigational | small molecule | SGX-523 | Therapeutic strategy associated | Details |
| R0983 | DB06329 | investigational | small molecule | RG-7795 | Therapeutic strategy associated | Details |
| R0989 | DB06347 | investigational | small molecule | Cenisertib | Therapeutic strategy associated | Details |
| R0993 | DB06362 | investigational | small molecule | Becatecarin | Therapeutic strategy associated | Details |
| R0994 | DB06366 | approved | biotech | Pertuzumab | Therapeutic strategy associated | Details |
| R1008 | DB06421 | investigational | small molecule | Declopramide | Therapeutic strategy associated | Details |
| R1009 | DB06423 | investigational | biotech | Endostatin | Therapeutic strategy associated | Details |
| R1012 | DB06433 | investigational | small molecule | Tezacitabine | Therapeutic strategy associated | Details |
| R1022 | DB06467 | investigational | biotech | Apolizumab | Therapeutic strategy associated | Details |
| R1023 | DB06469 | investigational | small molecule | Lestaurtinib | Therapeutic strategy associated | Details |
| R1026 | DB06479 | investigational | small molecule | Propentofylline | Therapeutic strategy associated | Details |
| R1028 | DB06486 | investigational | small molecule | Enzastaurin | Therapeutic strategy associated | Details |
| R1051 | DB06589 | approved | small molecule | Pazopanib | Therapeutic strategy associated | Details |
| R1052 | DB06595 | approved; investigational | small molecule | Midostaurin | Therapeutic strategy associated | Details |
| R1053 | DB06599 | investigational | biotech | Lexatumumab | Therapeutic strategy associated | Details |
| R1067 | DB06641 | investigational | small molecule | Perifosine | Therapeutic strategy associated | Details |
| R1072 | DB06656 | investigational | small molecule | TAS-106 | Therapeutic strategy associated | Details |
| R1091 | DB06755 | approved; nutraceutical | small molecule | Beta carotene | Therapeutic strategy associated | Details |
| R1094 | DB06772 | approved | small molecule | Cabazitaxel | Therapeutic strategy associated | Details |
| R1102 | DB06791 | approved | small molecule | Lanreotide | Therapeutic strategy associated | Details |
| R1106 | DB06813 | approved; investigational | small molecule | Pralatrexate | Therapeutic strategy associated | Details |
| R1107 | DB06824 | approved; investigational | small molecule | Triethylenetetramine | Therapeutic strategy associated | Details |
| R1158 | DB08818 | approved; vet_approved | small molecule | Hyaluronic acid | Therapeutic strategy associated | Details |
| R1168 | DB08842 | approved; investigational | small molecule | Acetylcarnitine | Therapeutic strategy associated | Details |
| R1171 | DB08867 | approved | small molecule | Ulipristal | Therapeutic strategy associated | Details |
| R1172 | DB08870 | approved; investigational | biotech | Brentuximab vedotin | Target associated | Details |
| R1174 | DB08877 | approved | small molecule | Ruxolitinib | Therapeutic strategy associated | Details |
| R1177 | DB08881 | approved | small molecule | Vemurafenib | Therapeutic strategy associated | Details |
| R1179 | DB08889 | approved; investigational | small molecule | Carfilzomib | Therapeutic strategy associated | Details |
| R1182 | DB08899 | approved | small molecule | Enzalutamide | Therapeutic strategy associated | Details |
| R1183 | DB08904 | approved | biotech | Certolizumab pegol | Therapeutic strategy associated | Details |
| R1185 | DB08910 | approved | small molecule | Pomalidomide | Therapeutic strategy associated | Details |
| R1186 | DB08911 | approved | small molecule | Trametinib | Therapeutic strategy associated | Details |
| R1197 | DB09031 | approved; investigational | small molecule | Miltefosine | Therapeutic strategy associated | Details |
| R1204 | DB09053 | approved | small molecule | Ibrutinib | Therapeutic strategy associated | Details |
| R1205 | DB09054 | approved | small molecule | Idelalisib | Therapeutic strategy associated | Details |
| R1211 | DB09070 | approved; investigational | small molecule | Tibolone | Therapeutic strategy associated | Details |
| R1213 | DB09077 | approved; investigational | biotech | Dinutuximab | Therapeutic strategy associated | Details |
| R1214 | DB09079 | approved | small molecule | Nintedanib | Therapeutic strategy associated | Details |
| R1223 | DB09099 | approved; investigational | small molecule | Somatostatin | Therapeutic strategy associated | Details |
| R1234 | DB09140 | approved; vet_approved | small molecule | Oxygen | Therapeutic strategy associated | Details |
| R1244 | DB09213 | approved; investigational | small molecule | Dexibuprofen | Therapeutic strategy associated | Details |
| R1276 | DB09267 | approved; withdrawn | small molecule | Strontium ranelate | Therapeutic strategy associated | Details |
| R1301 | DB09331 | approved | biotech | Daratumumab | Therapeutic strategy associated | Details |
| R1314 | DB09496 | approved; investigational | small molecule | Octinoxate | Therapeutic strategy associated | Details |
| R1320 | DB09570 | approved; investigational | small molecule | Ixazomib | Therapeutic strategy associated | Details |
| R1340 | DB11125 | approved | small molecule | Benzethonium | Therapeutic strategy associated | Details |
| R1358 | DB11254 | approved | small molecule | Hexylresorcinol | Therapeutic strategy associated | Details |
| R1360 | DB11265 | nutraceutical | biotech | Curcuma xanthorrhiza oil | Therapeutic strategy associated | Details |
| R1368 | DB11338 | approved; nutraceutical | biotech | Clove oil | Therapeutic strategy associated | Details |
| R1377 | DB11581 | approved; investigational | small molecule | Venetoclax | Therapeutic strategy associated | Details |
| R1381 | DB11590 | approved | small molecule | Thimerosal | Therapeutic strategy associated | Details |
| R1383 | DB11605 | approved | small molecule | Myrrh | Therapeutic strategy associated | Details |
| R1385 | DB11626 | approved | biotech | Tasonermin | Therapeutic strategy associated | Details |
| R1388 | DB11641 | approved; investigational | small molecule | Vinflunine | Therapeutic strategy associated | Details |
| R1390 | DB11689 | approved; investigational | small molecule | Selumetinib | Therapeutic strategy associated | Details |
| R1403 | DB11772 | investigational | small molecule | Pilaralisib | Therapeutic strategy associated | Details |
| R1405 | DB11781 | investigational | small molecule | Tosedostat | Therapeutic strategy associated | Details |
| R1406 | DB11793 | approved; investigational | small molecule | Niraparib | Therapeutic strategy associated | Details |
| R1411 | DB11830 | investigational | small molecule | Mocetinostat | Therapeutic strategy associated | Details |
| R1420 | DB11942 | approved; investigational | small molecule | Selinexor | Therapeutic strategy associated | Details |
| R1424 | DB11976 | approved; investigational | biotech | Anifrolumab | Therapeutic strategy associated | Details |
| R1425 | DB11986 | approved; investigational | small molecule | Entrectinib | Therapeutic strategy associated | Details |
| R1426 | DB11988 | approved; investigational | biotech | Ocrelizumab | Therapeutic strategy associated | Details |