Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0601 | DB04348 | approved; experimental | small molecule | Taurocholic acid | Target associated | Details |
| R0602 | DB04377 | experimental | small molecule | Meglutol | Target associated | Details |
| R0603 | DB04447 | experimental | small molecule | 1,4-Dithiothreitol | Target associated | Details |
| R0604 | DB04465 | approved; experimental; investigational | small molecule | Lactose | Target associated | Details |
| R0605 | DB04519 | investigational | small molecule | Caprylic acid | Target associated | Details |
| R0606 | DB04552 | experimental | small molecule | Niflumic acid | Therapeutic strategy associated | Details |
| R0607 | DB04557 | experimental | small molecule | Arachidonic Acid | Target associated | Details |
| R0608 | DB04570 | approved; investigational | small molecule | Latamoxef | Indication associated | Details |
| R0609 | DB04574 | approved | small molecule | Estrone sulfate | Indication associated | Details |
| R0610 | DB04626 | experimental; vet_approved | small molecule | Apramycin | Indication associated | Details |
| R0611 | DB04689 | experimental | small molecule | 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID | Target associated | Details |
| R0612 | DB04690 | experimental | small molecule | Camptothecin | Therapeutic strategy associated | Details |
| R0613 | DB04701 | experimental | small molecule | S-Methyl glutathione | Target associated | Details |
| R0614 | DB04725 | investigational | small molecule | Licofelone | Therapeutic strategy associated | Details |
| R0615 | DB04743 | approved; investigational; withdrawn | small molecule | Nimesulide | Therapeutic strategy associated | Details |
| R0616 | DB04801 | experimental | small molecule | cis-Vaccenic acid | Target associated | Details |
| R0617 | DB04817 | approved; investigational; withdrawn | small molecule | Metamizole | Therapeutic strategy associated | Details |
| R0618 | DB04818 | withdrawn | small molecule | Iproniazid | Indication associated | Details |
| R0619 | DB04831 | withdrawn | small molecule | Tienilic acid | Indication associated | Details |
| R0620 | DB04832 | approved; withdrawn | small molecule | Zimelidine | Indication associated | Details |
| R0621 | DB04836 | illicit; withdrawn | small molecule | Amineptine | Indication associated | Details |
| R0622 | DB04838 | approved | small molecule | Cyclandelate | Indication associated | Details |
| R0623 | DB04840 | approved; investigational | small molecule | Debrisoquine | Indication associated | Details |
| R0624 | DB04846 | approved; investigational | small molecule | Celiprolol | Therapeutic strategy associated | Details |
| R0625 | DB04852 | investigational | small molecule | Implitapide | Indication associated | Details |
| R0626 | DB04854 | approved | small molecule | Febuxostat | Therapeutic strategy associated | Details |
| R0627 | DB04855 | approved | small molecule | Dronedarone | Therapeutic strategy associated | Details |
| R0628 | DB04856 | investigational | small molecule | Dexloxiglumide | Indication associated | Details |
| R0629 | DB04861 | approved; investigational | small molecule | Nebivolol | Therapeutic strategy associated | Details |
| R0630 | DB04863 | investigational | small molecule | Lefradafiban | Therapeutic strategy associated | Details |
| R0631 | DB04870 | investigational | small molecule | Oleoyl-estrone | Indication associated | Details |
| R0632 | DB04871 | approved | small molecule | Lorcaserin | Therapeutic strategy associated | Details |
| R0633 | DB04872 | investigational | small molecule | Osanetant | Indication associated | Details |
| R0634 | DB04873 | investigational | small molecule | Piboserod | Indication associated | Details |
| R0635 | DB04874 | investigational | small molecule | Picoplatin | Therapeutic strategy associated | Details |
| R0636 | DB04875 | investigational | small molecule | Pralnacasan | Therapeutic strategy associated | Details |
| R0637 | DB04878 | investigational | small molecule | Voglibose | Indication associated | Details |
| R0638 | DB04883 | investigational | small molecule | Darusentan | Indication associated | Details |
| R0639 | DB04885 | investigational | small molecule | Cilansetron | Indication associated | Details |
| R0640 | DB04889 | investigational | small molecule | Bicifadine | Therapeutic strategy associated | Details |
| R0641 | DB04897 | approved; investigational | biotech | Lucinactant | Therapeutic strategy associated | Details |
| R0642 | DB04900 | investigational | biotech | Thymalfasin | Therapeutic strategy associated | Details |
| R0643 | DB04901 | investigational | biotech | Galiximab | Indication associated | Details |
| R0644 | DB04915 | investigational | small molecule | Idronoxil | Therapeutic strategy associated | Details |
| R0645 | DB04917 | investigational | small molecule | Renzapride | Indication associated | Details |
| R0646 | DB04918 | approved; investigational | small molecule | Ceftobiprole | Indication associated | Details |
| R0647 | DB04919 | investigational | biotech | Alfimeprase | Indication associated | Details |
| R0648 | DB04920 | approved; investigational | small molecule | Clevidipine | Indication associated | Details |
| R0649 | DB04924 | investigational | small molecule | Itopride | Therapeutic strategy associated | Details |
| R0650 | DB04925 | investigational | biotech | Desmoteplase | Indication associated | Details |
| R0651 | DB04929 | investigational | small molecule | DG031 | Indication associated | Details |
| R0652 | DB04932 | approved; investigational | biotech | Defibrotide | Therapeutic strategy associated | Details |
| R0653 | DB04933 | investigational | small molecule | Eritoran | Target associated | Details |
| R0654 | DB04934 | investigational | small molecule | Rifalazil | Therapeutic strategy associated | Details |
| R0655 | DB04936 | investigational | small molecule | Tagatose | Indication associated | Details |
| R0656 | DB04944 | investigational | small molecule | Acadesine | Therapeutic strategy associated | Details |
| R0657 | DB04949 | investigational | biotech | Pexelizumab | Therapeutic strategy associated | Details |
| R0658 | DB04951 | approved; investigational | small molecule | Pirfenidone | Therapeutic strategy associated | Details |
| R0659 | DB04952 | investigational | small molecule | Ramoplanin | Indication associated | Details |
| R0660 | DB04954 | investigational | small molecule | Tecadenoson | Indication associated | Details |
| R0661 | DB04956 | investigational | biotech | Afelimomab | Target associated | Details |
| R0662 | DB04957 | investigational | small molecule | Azimilide | Indication associated | Details |
| R0663 | DB04963 | investigational | biotech | rhGAD65 | Indication associated | Details |
| R0664 | DB04971 | investigational | small molecule | Reglitazar | Target associated | Details |
| R0665 | DB04974 | investigational | small molecule | Rimiducid | Therapeutic strategy associated | Details |
| R0666 | DB04977 | investigational | small molecule | Plitidepsin | Therapeutic strategy associated | Details |
| R0667 | DB04979 | investigational | biotech | AVR118 | Therapeutic strategy associated | Details |
| R0668 | DB04980 | investigational | small molecule | Lemuteporfin | Therapeutic strategy associated | Details |
| R0669 | DB04985 | investigational | biotech | Tigapotide | Therapeutic strategy associated | Details |
| R0670 | DB04987 | investigational | biotech | P113D | Indication associated | Details |
| R0671 | DB04991 | investigational | small molecule | XL784 | Therapeutic strategy associated | Details |
| R0672 | DB04999 | investigational | small molecule | MBO7133 | Therapeutic strategy associated | Details |
| R0673 | DB05001 | investigational | small molecule | PSN9301 | Therapeutic strategy associated | Details |
| R0674 | DB05003 | investigational | small molecule | Imexon | Therapeutic strategy associated | Details |
| R0675 | DB05004 | investigational | small molecule | Peptide YY (3-36) | Indication associated | Details |
| R0676 | DB05015 | approved; investigational | small molecule | Belinostat | Therapeutic strategy associated | Details |
| R0677 | DB05017 | investigational | small molecule | YSIL6 | Target associated | Details |
| R0678 | DB05025 | investigational | small molecule | Arimoclomol | Indication associated | Details |
| R0679 | DB05027 | investigational | small molecule | DG041 | Therapeutic strategy associated | Details |
| R0680 | DB05032 | investigational | small molecule | REV131 | Therapeutic strategy associated | Details |
| R0681 | DB05035 | investigational | small molecule | Eprotirome | Target associated | Details |
| R0682 | DB05044 | investigational | small molecule | PSN357 | Indication associated | Details |
| R0683 | DB05045 | investigational | small molecule | Obinepitide | Indication associated | Details |
| R0684 | DB05048 | investigational | small molecule | Cannabinor | Therapeutic strategy associated | Details |
| R0685 | DB05049 | investigational | small molecule | DDP733 | Indication associated | Details |
| R0686 | DB05051 | investigational | small molecule | BZL101 | Therapeutic strategy associated | Details |
| R0687 | DB05053 | investigational | small molecule | MB-07803 | Indication associated | Details |
| R0688 | DB05054 | investigational | small molecule | AN0128 | Therapeutic strategy associated | Details |
| R0689 | DB05061 | investigational | small molecule | GFT14 | Indication associated | Details |
| R0690 | DB05064 | investigational | small molecule | INCB13739 | Therapeutic strategy associated | Details |
| R0691 | DB05068 | investigational | small molecule | ATG002 | Indication associated | Details |
| R0692 | DB05072 | investigational | small molecule | AV608 | Therapeutic strategy associated | Details |
| R0693 | DB05075 | investigational | small molecule | TG-100801 | Therapeutic strategy associated | Details |
| R0694 | DB05077 | investigational | small molecule | SLV319 | Indication associated | Details |
| R0695 | DB05080 | investigational | small molecule | OBE101 | Indication associated | Details |
| R0696 | DB05084 | approved; investigational | biotech | Abaloparatide | Indication associated | Details |
| R0697 | DB05088 | investigational | small molecule | Tetrathiomolybdate | Therapeutic strategy associated | Details |
| R0698 | DB05093 | investigational | small molecule | AX200 | Indication associated | Details |
| R0699 | DB05095 | investigational | small molecule | Cimicoxib | Therapeutic strategy associated | Details |
| R0700 | DB05098 | investigational | small molecule | Leptin | Therapeutic strategy associated | Details |