Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
Search for:
depression115 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0036 | DB00120 | approved; investigational; nutraceutical | small molecule | Phenylalanine | Indication associated | Details |
| R0037 | DB00121 | approved; investigational; nutraceutical | small molecule | Biotin | Target associated | Details |
| R0052 | DB00150 | approved; nutraceutical; withdrawn | small molecule | Tryptophan | Indication associated | Details |
| R0055 | DB00157 | approved; nutraceutical | small molecule | NADH | Target associated | Details |
| R0063 | DB00176 | approved; investigational | small molecule | Fluvoxamine | Indication associated | Details |
| R0068 | DB00182 | approved; illicit; investigational | small molecule | Amphetamine | Indication associated | Details |
| R0071 | DB00193 | approved; investigational | small molecule | Tramadol | Therapeutic strategy associated | Details |
| R0074 | DB00201 | approved | small molecule | Caffeine | Indication associated | Details |
| R0082 | DB00215 | approved | small molecule | Citalopram | Indication associated | Details |
| R0091 | DB00234 | approved; experimental | small molecule | Reboxetine | Indication associated | Details |
| R0103 | DB00281 | approved; vet_approved | small molecule | Lidocaine | Therapeutic strategy associated | Details |
| R0112 | DB00313 | approved; investigational | small molecule | Valproic acid | Therapeutic strategy associated | Details |
| R0113 | DB00321 | approved | small molecule | Amitriptyline | Indication associated | Details |
| R0118 | DB00333 | approved | small molecule | Methadone | Therapeutic strategy associated | Details |
| R0119 | DB00334 | approved; investigational | small molecule | Olanzapine | Indication associated | Details |
| R0120 | DB00335 | approved | small molecule | Atenolol | Therapeutic strategy associated | Details |
| R0124 | DB00344 | approved | small molecule | Protriptyline | Indication associated | Details |
| R0137 | DB00381 | approved | small molecule | Amlodipine | Therapeutic strategy associated | Details |
| R0143 | DB00404 | approved; illicit; investigational | small molecule | Alprazolam | Indication associated | Details |
| R0153 | DB00458 | approved | small molecule | Imipramine | Indication associated | Details |
| R0160 | DB00472 | approved; vet_approved | small molecule | Fluoxetine | Indication associated | Details |
| R0161 | DB00476 | approved | small molecule | Duloxetine | Therapeutic strategy associated | Details |
| R0171 | DB00498 | approved; investigational | small molecule | Phenindione | Indication associated | Details |
| R0173 | DB00504 | approved | small molecule | Levallorphan | Indication associated | Details |
| R0183 | DB00540 | approved | small molecule | Nortriptyline | Indication associated | Details |
| R0185 | DB00543 | approved | small molecule | Amoxapine | Indication associated | Details |
| R0189 | DB00555 | approved; investigational | small molecule | Lamotrigine | Indication associated | Details |
| R0245 | DB00696 | approved | small molecule | Ergotamine | Therapeutic strategy associated | Details |
| R0251 | DB00715 | approved; investigational | small molecule | Paroxetine | Indication associated | Details |
| R0255 | DB00726 | approved | small molecule | Trimipramine | Indication associated | Details |
| R0258 | DB00734 | approved; investigational | small molecule | Risperidone | Indication associated | Details |
| R0278 | DB00780 | approved | small molecule | Phenelzine | Indication associated | Details |
| R0287 | DB00805 | approved | small molecule | Minaprine | Indication associated | Details |
| R0300 | DB00834 | approved; investigational | small molecule | Mifepristone | Indication associated | Details |
| R0310 | DB00859 | approved | small molecule | Penicillamine | Indication associated | Details |
| R0319 | DB00875 | approved; investigational; withdrawn | small molecule | Flupentixol | Indication associated | Details |
| R0337 | DB00934 | approved; investigational | small molecule | Maprotiline | Indication associated | Details |
| R0342 | DB00946 | approved; investigational | small molecule | Phenprocoumon | Indication associated | Details |
| R0381 | DB01037 | approved; investigational; vet_approved | small molecule | Selegiline | Indication associated | Details |
| R0405 | DB01104 | approved | small molecule | Sertraline | Indication associated | Details |
| R0423 | DB01142 | approved; investigational | small molecule | Doxepin | Indication associated | Details |
| R0425 | DB01149 | approved; withdrawn | small molecule | Nefazodone | Indication associated | Details |
| R0427 | DB01151 | approved; investigational | small molecule | Desipramine | Indication associated | Details |
| R0429 | DB01156 | approved | small molecule | Bupropion | Indication associated | Details |
| R0437 | DB01183 | approved; vet_approved | small molecule | Naloxone | Target associated | Details |
| R0452 | DB01221 | approved; vet_approved | small molecule | Ketamine | Indication associated | Details |
| R0455 | DB01224 | approved | small molecule | Quetiapine | Indication associated | Details |
| R0462 | DB01242 | approved; investigational; vet_approved | small molecule | Clomipramine | Indication associated | Details |
| R0464 | DB01247 | approved | small molecule | Isocarboxazid | Indication associated | Details |
| R0501 | DB01356 | experimental | small molecule | Lithium cation | Indication associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0524 | DB01440 | approved; illicit; investigational | small molecule | gamma-Hydroxybutyric acid | Indication associated | Details |
| R0526 | DB01489 | experimental; illicit | small molecule | Camazepam | Indication associated | Details |
| R0529 | DB01563 | approved; illicit; investigational; vet_approved | small molecule | Chloral hydrate | Indication associated | Details |
| R0574 | DB03017 | approved; experimental | small molecule | Lauric acid | Target associated | Details |
| R0618 | DB04818 | withdrawn | small molecule | Iproniazid | Indication associated | Details |
| R0620 | DB04832 | approved; withdrawn | small molecule | Zimelidine | Indication associated | Details |
| R0621 | DB04836 | illicit; withdrawn | small molecule | Amineptine | Indication associated | Details |
| R0633 | DB04872 | investigational | small molecule | Osanetant | Indication associated | Details |
| R0699 | DB05095 | investigational | small molecule | Cimicoxib | Therapeutic strategy associated | Details |
| R0705 | DB05118 | investigational | small molecule | R1204 | Indication associated | Details |
| R0712 | DB05132 | investigational | small molecule | ND1251 | Indication associated | Details |
| R0717 | DB05142 | investigational | small molecule | ND7001 | Indication associated | Details |
| R0737 | DB05205 | investigational | small molecule | CX157 | Indication associated | Details |
| R0763 | DB05301 | investigational | small molecule | LAX-101 | Target associated | Details |
| R0774 | DB05339 | investigational | small molecule | MN-305 | Indication associated | Details |
| R0782 | DB05395 | investigational | small molecule | Amibegron | Indication associated | Details |
| R0790 | DB05418 | investigational | small molecule | GW 597599 | Indication associated | Details |
| R0791 | DB05421 | investigational | small molecule | CP-122721 | Indication associated | Details |
| R0792 | DB05422 | investigational | small molecule | OPC-14523 | Indication associated | Details |
| R0793 | DB05423 | investigational | small molecule | ORG-34517 | Indication associated | Details |
| R0808 | DB05466 | investigational | small molecule | R673 | Indication associated | Details |
| R0834 | DB05562 | investigational | small molecule | Naluzotan | Indication associated | Details |
| R0839 | DB05642 | investigational | small molecule | DDP-225 | Indication associated | Details |
| R0846 | DB05676 | approved; investigational | small molecule | Apremilast | Therapeutic strategy associated | Details |
| R0876 | DB05805 | investigational | small molecule | NS-2359 | Indication associated | Details |
| R0892 | DB05888 | investigational | small molecule | MEM 1414 | Indication associated | Details |
| R0905 | DB05964 | investigational | small molecule | Amitifadine | Indication associated | Details |
| R0930 | DB06148 | approved; investigational | small molecule | Mianserin | Indication associated | Details |
| R0934 | DB06156 | investigational | small molecule | Tesofensine | Indication associated | Details |
| R1007 | DB06413 | approved; investigational | small molecule | Armodafinil | Indication associated | Details |
| R1020 | DB06455 | investigational | small molecule | Meclinertant | Indication associated | Details |
| R1033 | DB06506 | investigational | small molecule | Repinotan | Indication associated | Details |
| R1043 | DB06538 | investigational | small molecule | Robalzotan | Indication associated | Details |
| R1064 | DB06618 | investigational | small molecule | Cutamesine | Indication associated | Details |
| R1073 | DB06660 | investigational | small molecule | Saredutant | Indication associated | Details |
| R1167 | DB08838 | experimental | small molecule | Agmatine | Therapeutic strategy associated | Details |
| R1168 | DB08842 | approved; investigational | small molecule | Acetylcarnitine | Therapeutic strategy associated | Details |
| R1181 | DB08895 | approved; investigational | small molecule | Tofacitinib | Therapeutic strategy associated | Details |
| R1237 | DB09166 | experimental | small molecule | Etizolam | Therapeutic strategy associated | Details |
| R1238 | DB09185 | approved; investigational; withdrawn | small molecule | Viloxazine | Indication associated | Details |
| R1239 | DB09194 | withdrawn | small molecule | Etoperidone | Indication associated | Details |
| R1263 | DB09244 | experimental | small molecule | Pirlindole | Indication associated | Details |
| R1264 | DB09246 | withdrawn | small molecule | Benmoxin | Indication associated | Details |
| R1265 | DB09247 | withdrawn | small molecule | Iproclozide | Indication associated | Details |
| R1266 | DB09248 | withdrawn | small molecule | Mebanazine | Indication associated | Details |
| R1267 | DB09249 | withdrawn | small molecule | Octamoxin | Indication associated | Details |
| R1268 | DB09250 | withdrawn | small molecule | Pheniprazine | Indication associated | Details |
| R1269 | DB09251 | withdrawn | small molecule | Phenoxypropazine | Indication associated | Details |
| R1270 | DB09252 | withdrawn | small molecule | Pivhydrazine | Indication associated | Details |