CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01904 | BRD-A77722753 | hydralazine | -- | -- | -- | Details |
| C01905 | BRD-A77824596 | fluocinolone-acetonide | NR3C1 | Corticosteroid agonist; Glucocorticoid receptor agonist | -- | Details |
| C01906 | BRD-A77864279 | BRD-A77864279 | -- | -- | -- | Details |
| C01907 | BRD-A77907596 | BRD-A77907596 | -- | -- | -- | Details |
| C01908 | BRD-A77941182 | BRD-A77941182 | -- | -- | -- | Details |
| C01909 | BRD-A78042852 | BRD-A78042852 | -- | -- | -- | Details |
| C01910 | BRD-A78085235 | BRD-A78085235 | -- | -- | -- | Details |
| C01911 | BRD-A78125048 | BRD-A78125048 | -- | -- | -- | Details |
| C01912 | BRD-A78195072 | imexon | -- | -- | -- | Details |
| C01913 | BRD-A78210457 | RG7112 | -- | -- | RG-7112 | Details |
| C01914 | BRD-A78236793 | BRD-A78236793 | -- | -- | -- | Details |
| C01915 | BRD-A78253580 | tetracycline | -- | -- | -- | Details |
| C01916 | BRD-A78295502 | hydroquinine | -- | -- | -- | Details |
| C01917 | BRD-A78303415 | hyoscyamine | -- | -- | -- | Details |
| C01918 | BRD-A78322124 | dobutamine | ADRB1; ADRB2 | Adrenergic receptor agonist | -- | Details |
| C01919 | BRD-A78341343 | regadenoson | ADORA2A | Adenosine receptor agonist | -- | Details |
| C01920 | BRD-A78355490 | BRD-A78355490 | -- | -- | -- | Details |
| C01921 | BRD-A78360835 | cercosporin | -- | -- | -- | Details |
| C01922 | BRD-A78377521 | monastrol | KIF11 | Kinesin inhibitor | -- | Details |
| C01923 | BRD-A78391468 | prednisolone-hemisuccinate | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C01924 | BRD-A78723049 | cefotetan | -- | -- | -- | Details |
| C01925 | BRD-A78877355 | nefopam | -- | -- | -- | Details |
| C01926 | BRD-A78909648 | PATI-1-2-3 | -- | -- | -- | Details |
| C01927 | BRD-A78942461 | ICI-118551 | ADRB2 | Adrenergic receptor antagonist | -- | Details |
| C01928 | BRD-A78952587 | A-740003 | -- | -- | -- | Details |
| C01929 | BRD-A78971512 | calcifediol | VDR | Vitamin D receptor agonist | -- | Details |
| C01930 | BRD-A78982410 | BRD-A78982410 | -- | -- | -- | Details |
| C01931 | BRD-A79038507 | AGN-192403 | NISCH | Imidazoline receptor ligand | -- | Details |
| C01932 | BRD-A79052425 | SIB-1553A | -- | -- | -- | Details |
| C01933 | BRD-A79058669 | BRD-A79058669 | -- | -- | -- | Details |
| C01934 | BRD-A79067928 | etoposide | TOP2A; TOP2B | Topoisomerase inhibitor | -- | Details |
| C01935 | BRD-A79097167 | BRD-A79097167 | -- | -- | -- | Details |
| C01936 | BRD-A79226577 | tropisetron | HTR3A | Serotonin receptor antagonist | -- | Details |
| C01937 | BRD-A79237180 | ascorbic-acid | SLC23A1 | Antioxidant | -- | Details |
| C01938 | BRD-A79248021 | BRD-A79248021 | -- | -- | -- | Details |
| C01939 | BRD-A79314293 | BRD-A79314293 | -- | -- | cephalosporanic-acid | Details |
| C01940 | BRD-A79316179 | BRD-A79316179 | -- | -- | -- | Details |
| C01941 | BRD-A79431551 | 3-deazaadenosine | AHCY | Adenosylhomocysteinase inhibitor | 3-DEAZAADENOSINE | Details |
| C01942 | BRD-A79465854 | auranofin | -- | -- | -- | Details |
| C01943 | BRD-A79479878 | testosterone | -- | -- | -- | Details |
| C01944 | BRD-A79545933 | BRD-A79545933 | -- | -- | -- | Details |
| C01945 | BRD-A79672927 | tropicamide | CHRM3; CHRM4 | Acetylcholine receptor antagonist | -- | Details |
| C01946 | BRD-A79766688 | PF-3644022 | -- | -- | -- | Details |
| C01947 | BRD-A79768653 | sirolimus | FKBP1A; MTOR | MTOR inhibitor | -- | Details |
| C01948 | BRD-A79803969 | memantine | GRIN1 | Glutamate receptor antagonist | -- | Details |
| C01949 | BRD-A79884839 | BRD-A79884839 | -- | -- | -- | Details |
| C01950 | BRD-A79903587 | tegafur | TYMS | Thymidylate synthase inhibitor | -- | Details |
| C01951 | BRD-A79981887 | midodrine | ADRA1D; ADRA1B; ADRA1A | Adrenergic receptor agonist | -- | Details |
| C01952 | BRD-A80010944 | BRD-A80010944 | -- | -- | -- | Details |
| C01953 | BRD-A80017228 | bendroflumethiazide | SLC12A3 | Sodium/potassium/chloride transporter inhibitor | -- | Details |
| C01954 | BRD-A80035237 | BRD-A80035237 | -- | -- | -- | Details |
| C01955 | BRD-A80057650 | BRD-A80057650 | -- | -- | -- | Details |
| C01956 | BRD-A80081229 | BRD-A80081229 | -- | -- | -- | Details |
| C01957 | BRD-A80151636 | bromocriptine | ADRA2A; ADRA2B; ADRA2C; DRD1; DRD2; DRD3; DRD4; DRD5; HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C | Dopamine receptor agonist | -- | Details |
| C01958 | BRD-A80213327 | NSC-23766 | -- | -- | -- | Details |
| C01959 | BRD-A80280426 | AD-5467 | AKR1B1 | Aldose reductase inhibitor | -- | Details |
| C01960 | BRD-A80383043 | BRD-A80383043 | -- | -- | 4-carboxy-3-hydroxyphenylglycine-(RS) | Details |
| C01961 | BRD-A80386041 | KUC103423N | -- | -- | KUC-103423N | Details |
| C01962 | BRD-A80502530 | cinobufagin | ATP1A1 | ATPase inhibitor | -- | Details |
| C01963 | BRD-A80536908 | BRD-A80536908 | -- | -- | -- | Details |
| C01964 | BRD-A80567352 | aceclidine | CHRM1; CHRM2; CHRM3; CHRM4; CHRM5 | Acetylcholine receptor agonist | -- | Details |
| C01965 | BRD-A80574334 | oxalomalic-acid | IDH1; ACO1 | Isocitrate dehydrogenase inhibitor | -- | Details |
| C01966 | BRD-A80594172 | betamethasone-valerate | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C01967 | BRD-A80638690 | floxuridine | -- | -- | -- | Details |
| C01968 | BRD-A80641450 | FR-139317 | EDNRA | Endothelin receptor antagonist | -- | Details |
| C01969 | BRD-A80705936 | BRD-A80705936 | -- | -- | -- | Details |
| C01970 | BRD-A80723361 | BRD-A80723361 | -- | -- | -- | Details |
| C01971 | BRD-A80775386 | hyperforin | ALOX5; PTGS1; NR1I2 | Lipoxygenase inhibitor; Cyclooxygenase inhibitor; Dopamine uptake inhibitor; Serotonin reuptake inhibitor; Interleukin receptor antagonist | -- | Details |
| C01972 | BRD-A80788753 | EMF-sumo1-10 | -- | -- | -- | Details |
| C01973 | BRD-A80793822 | pemoline | -- | -- | -- | Details |
| C01974 | BRD-A80869209 | ticarcillin | -- | -- | -- | Details |
| C01975 | BRD-A80871782 | hydroxyamphetamine | TAAR1 | Trace amine associated receptor agonist | -- | Details |
| C01976 | BRD-A80908310 | cloperastine | -- | -- | -- | Details |
| C01977 | BRD-A80928489 | 1-monopalmitin | ABCB1 | P-glycoprotein inhibitor | 1-MONOPALMITIN | Details |
| C01978 | BRD-A80960055 | celastrol | -- | -- | -- | Details |
| C01979 | BRD-A80968824 | BRD-A80968824 | -- | -- | -- | Details |
| C01980 | BRD-A81045722 | BRD-A81045722 | -- | -- | -- | Details |
| C01981 | BRD-A81129465 | fenoprofen | PTGS1 | Prostagladin inhibitor | -- | Details |
| C01982 | BRD-A81177136 | KN-62 | P2RX7; CAMK2A | Purinergic receptor antagonist; Calcium/calmodulin dependent protein kinase inhibitor | -- | Details |
| C01983 | BRD-A81233518 | glycopyrrolate | CHRM1; CHRM2; CHRM3 | Acetylcholine receptor antagonist | -- | Details |
| C01984 | BRD-A81260764 | BRD-A81260764 | -- | -- | -- | Details |
| C01985 | BRD-A81282034 | BRD-A81282034 | -- | -- | -- | Details |
| C01986 | BRD-A81370665 | BI-D1870 | RPS6KA1; RPS6KA2; RPS6KA3 | Ribosomal protein inhibitor | -- | Details |
| C01987 | BRD-A81372523 | BRD-A81372523 | -- | -- | -- | Details |
| C01988 | BRD-A81377415 | BRD-A81377415 | CLK1; DYRK1A; CLK4; DYRK1B | CLK inhibitor; DYRK inhibitor | -- | Details |
| C01989 | BRD-A81389811 | BRD-A81389811 | -- | -- | -- | Details |
| C01990 | BRD-A81392774 | BRD-A81392774 | -- | -- | -- | Details |
| C01991 | BRD-A81402010 | KU-C103443N | -- | -- | -- | Details |
| C01992 | BRD-A81407814 | BRD-A81407814 | -- | -- | -- | Details |
| C01993 | BRD-A81416315 | BRD-A81416315 | -- | -- | -- | Details |
| C01994 | BRD-A81472640 | BRD-A81472640 | -- | -- | -- | Details |
| C01995 | BRD-A81513827 | saxagliptin | DPP4 | Dipeptidyl peptidase inhibitor | -- | Details |
| C01996 | BRD-A81530502 | BRD-A81530502 | -- | -- | -- | Details |
| C01997 | BRD-A81541225 | oligomycin-a | ATP5F1A | ATPase inhibitor; ATP synthase inhibitor | -- | Details |
| C01998 | BRD-A81552806 | BRD-A81552806 | -- | -- | -- | Details |
| C01999 | BRD-A81585303 | acadesine | -- | -- | -- | Details |
| C02000 | BRD-A81615860 | BRD-A81615860 | -- | -- | fenclonine-(+/-) | Details |
| C02001 | BRD-A81772229 | simvastatin | HMGCR | HMGCR inhibitor | -- | Details |
| C02002 | BRD-A81795050 | U-18666A | -- | -- | -- | Details |
| C02003 | BRD-A81866333 | CGS-21680 | ADORA1; ADORA2A | Adenosine receptor agonist | -- | Details |