CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C01304 | BRD-A54632525 | BRD-A54632525 | ALOX12 | Lipoxygenase inhibitor | -- | Details |
| C01305 | BRD-A54635441 | levopropoxyphene | -- | -- | -- | Details |
| C01306 | BRD-A54769817 | BRD-A54769817 | -- | -- | -- | Details |
| C01307 | BRD-A54845972 | BRD-A54845972 | -- | -- | dihydroergotamine | Details |
| C01308 | BRD-A54880345 | etomidate | GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ | GABA receptor modulator; Membrane integrity inhibitor; Membrane permeability inhibitor | -- | Details |
| C01309 | BRD-A54927599 | KF-38789 | SELP | P selectin inhibitor | -- | Details |
| C01310 | BRD-A55020151 | BRD-A55020151 | -- | -- | -- | Details |
| C01311 | BRD-A55025683 | BRD-A55025683 | -- | -- | -- | Details |
| C01312 | BRD-A55063801 | BRD-A55063801 | -- | -- | -- | Details |
| C01313 | BRD-A55142378 | STK-674938 | -- | -- | -- | Details |
| C01314 | BRD-A55153871 | BRD-A55153871 | -- | -- | -- | Details |
| C01315 | BRD-A55236942 | BRD-A55236942 | -- | -- | -- | Details |
| C01316 | BRD-A55272860 | sulpiride | DRD2; DRD3; CA7 | Dopamine receptor antagonist | -- | Details |
| C01317 | BRD-A55317422 | BRD-A55317422 | -- | -- | -- | Details |
| C01318 | BRD-A55369275 | CGP-54626 | GABBR1; GABBR2 | GABA receptor antagonist | -- | Details |
| C01319 | BRD-A55393291 | testosterone | -- | -- | -- | Details |
| C01320 | BRD-A55408860 | BRD-A55408860 | -- | -- | -- | Details |
| C01321 | BRD-A55411938 | BRD-A55411938 | -- | -- | -- | Details |
| C01322 | BRD-A55416093 | colforsin | ADCY2; ADCY5 | Adenylyl cyclase activator | -- | Details |
| C01323 | BRD-A55424491 | methotrexate | DHFR | Dihydrofolate reductase inhibitor | methrotrexate | Details |
| C01324 | BRD-A55453956 | compound-e | -- | -- | -- | Details |
| C01325 | BRD-A55469827 | mephenesin | -- | -- | -- | Details |
| C01326 | BRD-A55484088 | BNTX | OPRD1 | Opioid receptor antagonist | bntx | Details |
| C01327 | BRD-A55521341 | BRD-A55521341 | -- | -- | -- | Details |
| C01328 | BRD-A55554369 | BRD-A55554369 | -- | -- | -- | Details |
| C01329 | BRD-A55565369 | BRD-A55565369 | -- | -- | -- | Details |
| C01330 | BRD-A55574211 | BRD-A55574211 | -- | -- | -- | Details |
| C01331 | BRD-A55579717 | cytisine | CHRNA2; CHRNA3; CHRNA4; CHRNA7; CHRNB2 | Acetylcholine receptor agonist | -- | Details |
| C01332 | BRD-A55594068 | vinblastine | TUBB | Tubulin inhibitor; Microtubule inhibitor | -- | Details |
| C01333 | BRD-A55609290 | BRD-A55609290 | -- | -- | -- | Details |
| C01334 | BRD-A55639867 | BRD-A55639867 | -- | -- | -- | Details |
| C01335 | BRD-A55722685 | BRD-A55722685 | -- | -- | -- | Details |
| C01336 | BRD-A55748233 | benzoin | -- | -- | -- | Details |
| C01337 | BRD-A55756846 | H-7 | -- | -- | -- | Details |
| C01338 | BRD-A55815733 | phylloquinone | -- | -- | -- | Details |
| C01339 | BRD-A55913614 | primaquine | -- | -- | -- | Details |
| C01340 | BRD-A55946879 | BW-B70C | ALOX5 | Lipoxygenase inhibitor | -- | Details |
| C01341 | BRD-A55962179 | omeprazole | ATP4A | ATPase inhibitor | -- | Details |
| C01342 | BRD-A56001686 | BRD-A56001686 | -- | -- | -- | Details |
| C01343 | BRD-A56012032 | thiorphan | MME | Membrane metalloendopeptidase inhibitor | -- | Details |
| C01344 | BRD-A56020723 | CA-074-Me | CTSB | Cathepsin inhibitor | -- | Details |
| C01345 | BRD-A56085258 | LGX-818 | -- | -- | -- | Details |
| C01346 | BRD-A56245458 | reichstein | AR | Androgen receptor antagonist | -- | Details |
| C01347 | BRD-A56332531 | BRD-A56332531 | -- | -- | -- | Details |
| C01348 | BRD-A56345662 | BRD-A56345662 | -- | -- | -- | Details |
| C01349 | BRD-A56359832 | zileuton | ALOX5 | Leukotriene inhibitor; Lipoxygenase inhibitor | -- | Details |
| C01350 | BRD-A56371469 | AGI-5198 | IDH1 | Isocitrate dehydrogenase inhibitor | -- | Details |
| C01351 | BRD-A56427952 | BRD-A56427952 | -- | -- | -- | Details |
| C01352 | BRD-A56470328 | BRD-A56470328 | -- | -- | fludrocortisone | Details |
| C01353 | BRD-A56498687 | dcv-gsh | -- | -- | -- | Details |
| C01354 | BRD-A56518012 | epirubicin | TOP2A | Topoisomerase inhibitor | -- | Details |
| C01355 | BRD-A56592690 | PX-12 | TXN; TXNRD1 | Thioredoxin inhibitor | -- | Details |
| C01356 | BRD-A56621826 | oxytetracycline | -- | -- | oxytetracycline.hcl | Details |
| C01357 | BRD-A56675431 | altizide | -- | -- | -- | Details |
| C01358 | BRD-A56702968 | nystatin | -- | -- | -- | Details |
| C01359 | BRD-A56798952 | bafilomycin | -- | -- | -- | Details |
| C01360 | BRD-A56800788 | BRD-A56800788 | -- | -- | -- | Details |
| C01361 | BRD-A56831909 | BRD-A56831909 | -- | -- | -- | Details |
| C01362 | BRD-A56858165 | cefadroxil | SLC15A1; SLC15A2; SLC22A6; SLC22A8 | Bacterial cell wall synthesis inhibitor | -- | Details |
| C01363 | BRD-A56884981 | BRD-A56884981 | -- | -- | -- | Details |
| C01364 | BRD-A56892734 | esomeprazole | ATP4A | ATPase inhibitor | -- | Details |
| C01365 | BRD-A56909893 | BRD-A56909893 | -- | -- | -- | Details |
| C01366 | BRD-A56987319 | SQ-22536 | ADCY1 | Adenylyl cyclase inhibitor | -- | Details |
| C01367 | BRD-A57089740 | peruvoside | -- | -- | -- | Details |
| C01368 | BRD-A57107094 | BRD-A57107094 | -- | -- | -- | Details |
| C01369 | BRD-A57133233 | chlorcyclizine | HRH1 | Histamine receptor antagonist | -- | Details |
| C01370 | BRD-A57152259 | CGS-21680 | ADORA1; ADORA2A | Adenosine receptor agonist | -- | Details |
| C01371 | BRD-A57174914 | BRD-A57174914 | -- | -- | -- | Details |
| C01372 | BRD-A57226833 | farnesylpyrophosphate | -- | -- | -- | Details |
| C01373 | BRD-A57285050 | BRD-A57285050 | -- | -- | -- | Details |
| C01374 | BRD-A57300602 | BRD-A57300602 | -- | -- | -- | Details |
| C01375 | BRD-A57353172 | BRD-A57353172 | -- | -- | -- | Details |
| C01376 | BRD-A57382968 | piroxicam | PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C01377 | BRD-A57457122 | VU-0400071-3 | GRM4 | Glutamate receptor modulator | -- | Details |
| C01378 | BRD-A57457448 | BRD-A57457448 | -- | -- | -- | Details |
| C01379 | BRD-A57474391 | BRD-A57474391 | -- | -- | -- | Details |
| C01380 | BRD-A57536034 | BRD-A57536034 | -- | -- | -- | Details |
| C01381 | BRD-A57581879 | myclobutanil | -- | -- | -- | Details |
| C01382 | BRD-A57594599 | BRD-A57594599 | -- | -- | 5-(3,5-dimethyl-1-piperidinyl)-2-(2-furyl)-1,3-oxazole-4-carbonitrile | Details |
| C01383 | BRD-A57762296 | BRD-A57762296 | -- | -- | -- | Details |
| C01384 | BRD-A57798559 | BRD-A57798559 | -- | -- | bicuculline-methochloride-(-) | Details |
| C01385 | BRD-A57905915 | norcitalopram | -- | -- | -- | Details |
| C01386 | BRD-A57957888 | citiolone | -- | -- | -- | Details |
| C01387 | BRD-A57982699 | BRD-A57982699 | -- | -- | -- | Details |
| C01388 | BRD-A58013617 | BRD-A58013617 | -- | -- | -- | Details |
| C01389 | BRD-A58048407 | nimodipine | NR3C2; CACNA1C; CACNA1D; CACNA1F; CACNA1S | Calcium channel blocker | -- | Details |
| C01390 | BRD-A58157837 | butabindide | TPP2 | Tripeptidyl peptidase inhibitor | -- | Details |
| C01391 | BRD-A58207013 | pinacidil | ABCC9; ABCC8 | ATP channel activator; Potassium channel activator | -- | Details |
| C01392 | BRD-A58269583 | deoxyandirobin | -- | -- | -- | Details |
| C01393 | BRD-A58280226 | Y-27632 | ROCK1; ROCK2 | Rho associated kinase inhibitor | -- | Details |
| C01394 | BRD-A58482795 | BRD-A58482795 | -- | -- | -- | Details |
| C01395 | BRD-A58564983 | selamectin | -- | -- | -- | Details |
| C01396 | BRD-A58712619 | BRD-A58712619 | -- | -- | -- | Details |
| C01397 | BRD-A58753560 | budesonide | NR3C1 | Glucocorticoid receptor agonist | -- | Details |
| C01398 | BRD-A58767537 | afatinib | EGFR; ERBB2; ERBB4 | EGFR inhibitor | -- | Details |
| C01399 | BRD-A58781082 | BRD-A58781082 | -- | -- | -- | Details |
| C01400 | BRD-A58803929 | BRD-A58803929 | -- | -- | -- | Details |
| C01401 | BRD-A58837096 | ribostamycin | -- | -- | -- | Details |
| C01402 | BRD-A58897152 | BRD-A58897152 | -- | -- | -- | Details |
| C01403 | BRD-A58924247 | BRD-A58924247 | -- | -- | -- | Details |