Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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1608 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0501 | DB01356 | experimental | small molecule | Lithium cation | Indication associated | Details |
| R0502 | DB01359 | approved; investigational | small molecule | Penbutolol | Indication associated | Details |
| R0503 | DB01369 | approved | small molecule | Quinupristin | Indication associated | Details |
| R0504 | DB01377 | approved | small molecule | Magnesium oxide | Therapeutic strategy associated | Details |
| R0505 | DB01380 | approved; investigational | small molecule | Cortisone acetate | Therapeutic strategy associated | Details |
| R0506 | DB01381 | approved; investigational; nutraceutical | biotech | Ginkgo biloba | Therapeutic strategy associated | Details |
| R0507 | DB01382 | approved; investigational | small molecule | Glymidine | Indication associated | Details |
| R0508 | DB01384 | experimental | small molecule | Paramethasone | Therapeutic strategy associated | Details |
| R0509 | DB01390 | approved | small molecule | Sodium bicarbonate | Indication associated | Details |
| R0510 | DB01392 | approved; investigational; vet_approved | small molecule | Yohimbine | Indication associated | Details |
| R0511 | DB01394 | approved | small molecule | Colchicine | Therapeutic strategy associated | Details |
| R0512 | DB01395 | approved | small molecule | Drospirenone | Indication associated | Details |
| R0513 | DB01401 | approved | small molecule | Choline magnesium trisalicylate | Therapeutic strategy associated | Details |
| R0514 | DB01407 | approved; investigational; vet_approved | small molecule | Clenbuterol | Target associated | Details |
| R0515 | DB01410 | approved; investigational | small molecule | Ciclesonide | Therapeutic strategy associated | Details |
| R0516 | DB01411 | investigational | small molecule | Pranlukast | Target associated | Details |
| R0517 | DB01413 | approved; investigational | small molecule | Cefepime | Indication associated | Details |
| R0518 | DB01414 | experimental; vet_approved | small molecule | Cefacetrile | Indication associated | Details |
| R0519 | DB01418 | approved; investigational | small molecule | Acenocoumarol | Indication associated | Details |
| R0520 | DB01419 | approved | small molecule | Antrafenine | Therapeutic strategy associated | Details |
| R0521 | DB01424 | approved; withdrawn | small molecule | Aminophenazone | Therapeutic strategy associated | Details |
| R0522 | DB01427 | approved | small molecule | Amrinone | Target associated | Details |
| R0523 | DB01436 | approved; nutraceutical | small molecule | Alfacalcidol | Indication associated | Details |
| R0524 | DB01440 | approved; illicit; investigational | small molecule | gamma-Hydroxybutyric acid | Indication associated | Details |
| R0525 | DB01452 | approved; illicit; investigational | small molecule | Diamorphine | Therapeutic strategy associated | Details |
| R0526 | DB01489 | experimental; illicit | small molecule | Camazepam | Indication associated | Details |
| R0527 | DB01550 | experimental; illicit; withdrawn | small molecule | Fenproporex | Indication associated | Details |
| R0528 | DB01556 | illicit; withdrawn | small molecule | Chlorphentermine | Therapeutic strategy associated | Details |
| R0529 | DB01563 | approved; illicit; investigational; vet_approved | small molecule | Chloral hydrate | Indication associated | Details |
| R0530 | DB01577 | approved; illicit | small molecule | Metamfetamine | Indication associated | Details |
| R0531 | DB01579 | approved; illicit | small molecule | Phendimetrazine | Therapeutic strategy associated | Details |
| R0532 | DB01580 | approved | small molecule | Oxprenolol | Indication associated | Details |
| R0533 | DB01582 | approved; investigational; vet_approved | small molecule | Sulfamethazine | Indication associated | Details |
| R0534 | DB01583 | approved | small molecule | Liotrix | Target associated | Details |
| R0535 | DB01584 | approved; withdrawn | biotech | Thyroglobulin | Indication associated | Details |
| R0536 | DB01590 | approved | small molecule | Everolimus | Therapeutic strategy associated | Details |
| R0537 | DB01597 | approved; investigational | small molecule | Cilastatin | Indication associated | Details |
| R0538 | DB01598 | approved | small molecule | Imipenem | Indication associated | Details |
| R0539 | DB01600 | approved | small molecule | Tiaprofenic acid | Therapeutic strategy associated | Details |
| R0540 | DB01602 | approved; investigational | small molecule | Bacampicillin | Indication associated | Details |
| R0541 | DB01604 | approved | small molecule | Pivampicillin | Indication associated | Details |
| R0542 | DB01606 | approved | small molecule | Tazobactam | Indication associated | Details |
| R0543 | DB01607 | approved; investigational; vet_approved | small molecule | Ticarcillin | Indication associated | Details |
| R0544 | DB01611 | approved | small molecule | Hydroxychloroquine | Therapeutic strategy associated | Details |
| R0545 | DB01612 | approved | small molecule | Amyl Nitrite | Indication associated | Details |
| R0546 | DB01616 | approved; investigational | small molecule | Alverine | Therapeutic strategy associated | Details |
| R0547 | DB01625 | approved; vet_approved | small molecule | Isopropamide | Indication associated | Details |
| R0548 | DB01626 | approved | small molecule | Pargyline | Therapeutic strategy associated | Details |
| R0549 | DB01627 | approved; vet_approved | small molecule | Lincomycin | Indication associated | Details |
| R0550 | DB01628 | approved; investigational | small molecule | Etoricoxib | Indication associated | Details |
| R0551 | DB01669 | experimental | small molecule | Virginiamycin M1 | Indication associated | Details |
| R0552 | DB01708 | approved; investigational; nutraceutical | small molecule | Prasterone | Target associated | Details |
| R0553 | DB01764 | approved | small molecule | Dalfopristin | Indication associated | Details |
| R0554 | DB01783 | approved; nutraceutical; vet_approved | small molecule | Pantothenic acid | Indication associated | Details |
| R0555 | DB01827 | experimental | small molecule | 2,3,5,6-Tetrafluoro-4-Methoxy-Benzamide | Target associated | Details |
| R0556 | DB01890 | experimental | small molecule | N,N-Bis(3-(D-gluconamido)propyl)deoxycholamide | Target associated | Details |
| R0557 | DB01992 | investigational; nutraceutical | small molecule | Coenzyme A | Target associated | Details |
| R0558 | DB02106 | experimental | small molecule | [3,5-Dibromo-4-(4-Hydroxy-3-Phenethylcarbamoyl-Phenoxy)-Phenyl]-Acetic Acid | Target associated | Details |
| R0559 | DB02187 | experimental | small molecule | Equilin | Indication associated | Details |
| R0560 | DB02266 | approved | small molecule | Flufenamic acid | Target associated | Details |
| R0561 | DB02342 | investigational | small molecule | 2-Methoxyestradiol | Indication associated | Details |
| R0562 | DB02383 | withdrawn | small molecule | Tolrestat | Indication associated | Details |
| R0563 | DB02458 | experimental | small molecule | S-(2,4-dinitrophenyl)glutathione | Target associated | Details |
| R0564 | DB02509 | experimental | small molecule | Farnesol | Target associated | Details |
| R0565 | DB02545 | experimental | small molecule | Fexaramine | Target associated | Details |
| R0566 | DB02546 | approved; investigational | small molecule | Vorinostat | Therapeutic strategy associated | Details |
| R0567 | DB02638 | approved; investigational | small molecule | Terlipressin | Therapeutic strategy associated | Details |
| R0568 | DB02659 | approved | small molecule | Cholic Acid | Target associated | Details |
| R0569 | DB02703 | approved; investigational | small molecule | Fusidic acid | Indication associated | Details |
| R0570 | DB02746 | experimental | small molecule | Phthalic Acid | Target associated | Details |
| R0571 | DB02767 | experimental | small molecule | (R)-3-hydroxytetradecanoic acid | Target associated | Details |
| R0572 | DB02859 | experimental | small molecule | Soraphen A | Target associated | Details |
| R0573 | DB03010 | experimental; investigational | small molecule | Patupilone | Therapeutic strategy associated | Details |
| R0574 | DB03017 | approved; experimental | small molecule | Lauric acid | Target associated | Details |
| R0575 | DB03124 | experimental | small molecule | 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid | Target associated | Details |
| R0576 | DB03169 | experimental | small molecule | (S)-Hmg-Coa | Target associated | Details |
| R0577 | DB03176 | experimental | small molecule | KB-141 | Target associated | Details |
| R0578 | DB03181 | experimental | small molecule | 2-[4-(4-Hydroxy-3-Isopropyl-Phenoxy)-3,5-Dimethyl-Phenyl]-2h-[1,2,4]Triazine-3,5-Dione | Target associated | Details |
| R0579 | DB03193 | approved; experimental | small molecule | Stearic acid | Target associated | Details |
| R0580 | DB03310 | approved; experimental; investigational | small molecule | Glutathione disulfide | Target associated | Details |
| R0581 | DB03316 | experimental | small molecule | 1,4-Dioxane | Target associated | Details |
| R0582 | DB03338 | experimental | small molecule | Heptyl glucoside | Target associated | Details |
| R0583 | DB03384 | experimental | small molecule | Fica | Target associated | Details |
| R0584 | DB03461 | experimental | small molecule | Nicotinamide adenine dinucleotide phosphate | Target associated | Details |
| R0585 | DB03496 | experimental; investigational | small molecule | Alvocidib | Therapeutic strategy associated | Details |
| R0586 | DB03507 | experimental | small molecule | 6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One | Target associated | Details |
| R0587 | DB03518 | experimental | small molecule | Mevalonic acid | Target associated | Details |
| R0588 | DB03600 | experimental | small molecule | Capric acid | Target associated | Details |
| R0589 | DB03604 | investigational | small molecule | Tiratricol | Target associated | Details |
| R0590 | DB03619 | approved | small molecule | Deoxycholic acid | Therapeutic strategy associated | Details |
| R0591 | DB03781 | experimental | small molecule | 2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid | Target associated | Details |
| R0592 | DB03785 | experimental | small molecule | Mevinolinic acid | Target associated | Details |
| R0593 | DB03788 | experimental | small molecule | GC-24 | Target associated | Details |
| R0594 | DB03796 | approved | small molecule | Palmitic Acid | Target associated | Details |
| R0595 | DB03849 | investigational | small molecule | Cilomilast | Therapeutic strategy associated | Details |
| R0596 | DB04209 | approved; investigational | small molecule | Dequalinium | Therapeutic strategy associated | Details |
| R0597 | DB04224 | approved; investigational; vet_approved | small molecule | Oleic Acid | Target associated | Details |
| R0598 | DB04270 | experimental | small molecule | (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid | Target associated | Details |
| R0599 | DB04335 | experimental; investigational | small molecule | Inosine | Therapeutic strategy associated | Details |
| R0600 | DB04339 | approved; investigational | small molecule | Carbocisteine | Therapeutic strategy associated | Details |