CMap Candidates
CMap (Connectivity Map) candidates are extracted from CLUE (CMap and LINCS Unified Environment), with detailed information, e.g., perturbagen time and dose, compound structure, targets, SMILES, mechanism of action. Two publicly available gene expression profiles of NAFLD are used to calculate individual connectivity scores and corresponding statistical significances for these candidates.
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34330 records.
| CMap ID | Pert ID | Compound Name | Targets | MoA | Compound Aliases | |
|---|---|---|---|---|---|---|
| C00304 | BRD-A11968133 | BRD-A11968133 | -- | -- | -- | Details |
| C00305 | BRD-A11990600 | lorazepam | GABRA1; GABRA2; GABRA3; GABRA4; GABRA5; GABRA6; GABRB1; GABRB2; GABRB3; GABRD; GABRE; GABRG1; GABRG2; GABRG3; GABRP; GABRQ | Benzodiazepine receptor agonist | -- | Details |
| C00306 | BRD-A12016240 | LY-278584 | -- | -- | -- | Details |
| C00307 | BRD-A12077521 | cefepime | -- | -- | -- | Details |
| C00308 | BRD-A12083771 | BRD-A12083771 | -- | -- | -- | Details |
| C00309 | BRD-A12166214 | BRD-A12166214 | -- | -- | -- | Details |
| C00310 | BRD-A12230535 | nutlin-3 | MDM2 | MDM inhibitor | NUTLIN-3A | Details |
| C00311 | BRD-A12237696 | L-citrulline | -- | -- | l-citrulline | Details |
| C00312 | BRD-A12372458 | BRD-A12372458 | -- | -- | -- | Details |
| C00313 | BRD-A12409803 | orteronel | CYP17A1 | Cytochrome P450 inhibitor; Androgen receptor antagonist; Androgen biosynthesis inhibitor | -- | Details |
| C00314 | BRD-A12426960 | BRD-A12426960 | -- | -- | -- | Details |
| C00315 | BRD-A12560204 | nitrendipine | CACNA1C; CACNA1D; CACNA2D1 | Calcium channel blocker | -- | Details |
| C00316 | BRD-A12633378 | ML-213 | -- | -- | -- | Details |
| C00317 | BRD-A12643502 | BRD-A12643502 | -- | -- | -- | Details |
| C00318 | BRD-A12725272 | BRD-A12725272 | -- | -- | 2-Oxo-1-oxa-spiro[4.4]nonane-4-carboxylic acid 2,4-dimethyl-benzylamide | Details |
| C00319 | BRD-A12822115 | BRD-A12822115 | -- | -- | -- | Details |
| C00320 | BRD-A12830281 | BRD-A12830281 | -- | -- | -- | Details |
| C00321 | BRD-A12832192 | streptozotocin | -- | -- | -- | Details |
| C00322 | BRD-A12881497 | serotonin | HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C; HTR3A; HTR4; HTR5A; HTR6; HTR7; HTR3B | Growth factor receptor activator | -- | Details |
| C00323 | BRD-A12894472 | BRD-A12894472 | -- | -- | -- | Details |
| C00324 | BRD-A12896037 | cisapride | HTR4; KCNH2 | Serotonin receptor agonist | -- | Details |
| C00325 | BRD-A12994259 | pomalidomide | CRBN; TNF | Angiogenesis inhibitor; Tumor necrosis factor production inhibitor | -- | Details |
| C00326 | BRD-A13005505 | BRD-A13005505 | -- | -- | -- | Details |
| C00327 | BRD-A13020530 | BRD-A13020530 | -- | -- | -- | Details |
| C00328 | BRD-A13021932 | BMS-509744 | -- | -- | -- | Details |
| C00329 | BRD-A13082766 | BRD-A13082766 | -- | -- | -- | Details |
| C00330 | BRD-A13084692 | troglitazone | PPARG | Insulin sensitizer; PPAR receptor agonist | -- | Details |
| C00331 | BRD-A13122391 | triptolide | -- | -- | -- | Details |
| C00332 | BRD-A13133631 | BRD-A13133631 | -- | -- | fluorometholone | Details |
| C00333 | BRD-A13188892 | doxazosin | ADRA1D; ADRA1B; ADRA1A | Adrenergic receptor antagonist | -- | Details |
| C00334 | BRD-A13195221 | STK-064652 | -- | -- | -- | Details |
| C00335 | BRD-A13210451 | BRD-A13210451 | -- | -- | -- | Details |
| C00336 | BRD-A13254067 | okadaic-acid | -- | -- | -- | Details |
| C00337 | BRD-A13323580 | perillyl-alcohol | FNTA | Apoptosis stimulant; Cell cycle inhibitor; Farnesyltransferase inhibitor | -- | Details |
| C00338 | BRD-A13346522 | BRD-A13346522 | -- | -- | -- | Details |
| C00339 | BRD-A13367427 | BRD-A13367427 | -- | -- | -- | Details |
| C00340 | BRD-A13461302 | BRD-A13461302 | -- | -- | -- | Details |
| C00341 | BRD-A13548575 | BRD-A13548575 | -- | -- | -- | Details |
| C00342 | BRD-A13592825 | BRD-A13592825 | -- | -- | -- | Details |
| C00343 | BRD-A13650332 | flucloxacillin | -- | -- | -- | Details |
| C00344 | BRD-A13689093 | ONO-4059 | -- | -- | -- | Details |
| C00345 | BRD-A13711138 | alcuronium | -- | -- | -- | Details |
| C00346 | BRD-A13806944 | BRD-A13806944 | -- | -- | -- | Details |
| C00347 | BRD-A13807286 | HA-14-1 | BCL2 | BCL inhibitor | -- | Details |
| C00348 | BRD-A13914662 | BRD-A13914662 | -- | -- | -- | Details |
| C00349 | BRD-A13946108 | sulindac | AKR1B1; PTGS1; PTGS2 | Cyclooxygenase inhibitor | -- | Details |
| C00350 | BRD-A13964793 | TC-1 | -- | -- | -- | Details |
| C00351 | BRD-A13982089 | ephedrine | -- | -- | -- | Details |
| C00352 | BRD-A13983189 | BRD-A13983189 | -- | -- | -- | Details |
| C00353 | BRD-A14014306 | BRD-A14014306 | -- | -- | -- | Details |
| C00354 | BRD-A14098586 | BRD-A14098586 | -- | -- | -- | Details |
| C00355 | BRD-A14149633 | BRD-A14149633 | -- | -- | -- | Details |
| C00356 | BRD-A14178283 | BRD-A14178283 | -- | -- | -- | Details |
| C00357 | BRD-A14183911 | BRD-A14183911 | -- | -- | -- | Details |
| C00358 | BRD-A14208071 | oxyphenonium | CHRM1 | Cholinergic receptor antagonist | -- | Details |
| C00359 | BRD-A14233223 | BRD-A14233223 | -- | -- | -- | Details |
| C00360 | BRD-A14240607 | octopamine | -- | -- | -- | Details |
| C00361 | BRD-A14262390 | guanadrel | SLC6A2 | Adrenergic inhibitor | -- | Details |
| C00362 | BRD-A14331394 | BRD-A14331394 | -- | -- | -- | Details |
| C00363 | BRD-A14344385 | IDRA-21 | -- | -- | -- | Details |
| C00364 | BRD-A14395271 | mesoridazine | DRD2; HTR2A | Dopamine receptor antagonist | -- | Details |
| C00365 | BRD-A14424697 | BRD-A14424697 | -- | -- | -- | Details |
| C00366 | BRD-A14484404 | BRD-A14484404 | -- | -- | -- | Details |
| C00367 | BRD-A14564019 | 620_7033_4267 | -- | -- | -- | Details |
| C00368 | BRD-A14566392 | scopolamine | CHRM1; CHRM2; CHRM3; CHRM4 | Acetylcholine receptor antagonist | -- | Details |
| C00369 | BRD-A14574269 | UB-165 | CHRNA3; CHRNA4; CHRNB2 | Acetylcholine receptor agonist | -- | Details |
| C00370 | BRD-A14634327 | GSK-126 | -- | -- | -- | Details |
| C00371 | BRD-A14652656 | bucladesine | PRKACA | CAMP stimulant; Adenosine receptor agonist | -- | Details |
| C00372 | BRD-A14792000 | valsartan | AGTR1 | Angiotensin receptor antagonist | -- | Details |
| C00373 | BRD-A14795281 | BRD-A14795281 | -- | -- | -- | Details |
| C00374 | BRD-A14798026 | mestranol | ESR1 | Estrogen receptor agonist | -- | Details |
| C00375 | BRD-A14803952 | BRD-A14803952 | -- | -- | -- | Details |
| C00376 | BRD-A14842104 | BRD-A14842104 | -- | -- | -- | Details |
| C00377 | BRD-A14878925 | BRD-A14878925 | -- | -- | -- | Details |
| C00378 | BRD-A14886633 | norgestrel | -- | -- | -- | Details |
| C00379 | BRD-A14941520 | dofequidar | ABCC1; ABCB1 | MRP inhibitor; P-glycoprotein inhibitor | -- | Details |
| C00380 | BRD-A14966924 | alaproclate | SLC6A4 | Serotonin receptor antagonist | -- | Details |
| C00381 | BRD-A14969012 | SKF-83822 | -- | -- | -- | Details |
| C00382 | BRD-A14985772 | L-ascorbyl-6-palmitate | -- | -- | -- | Details |
| C00383 | BRD-A14999564 | BRD-A14999564 | -- | -- | geranyl-geranyl-pyrophosphate | Details |
| C00384 | BRD-A15010982 | HU-211 | CNR1; CNR2; GRIN1 | Glutamate receptor antagonist | -- | Details |
| C00385 | BRD-A15034104 | bergenin | IL1B; TNF | Interleukin inhibitor | -- | Details |
| C00386 | BRD-A15070535 | bucladesine | PRKACA | CAMP stimulant; Adenosine receptor agonist | -- | Details |
| C00387 | BRD-A15079084 | BRD-A15079084 | -- | -- | phorbol-12-myristate-13-acetate | Details |
| C00388 | BRD-A15086915 | BRD-A15086915 | -- | -- | -- | Details |
| C00389 | BRD-A15100685 | avicin-d | -- | -- | -- | Details |
| C00390 | BRD-A15113563 | BRD-A15113563 | -- | -- | -- | Details |
| C00391 | BRD-A15131297 | benazepril | ACE | Angiotensin converting enzyme inhibitor | -- | Details |
| C00392 | BRD-A15202882 | milnacipran | SLC6A2; SLC6A4 | Serotonin reuptake inhibitor | -- | Details |
| C00393 | BRD-A15297126 | fluocinolone-acetonide | NR3C1 | Corticosteroid agonist; Glucocorticoid receptor agonist | -- | Details |
| C00394 | BRD-A15330900 | BRD-A15330900 | -- | -- | -- | Details |
| C00395 | BRD-A15415227 | GW-1929 | PPARG | Insulin sensitizer; PPAR receptor agonist | -- | Details |
| C00396 | BRD-A15435692 | BMY-14802 | HTR1A | Sigma receptor antagonist | -- | Details |
| C00397 | BRD-A15454510 | BRD-A15454510 | -- | -- | -- | Details |
| C00398 | BRD-A15493168 | tetracycline | -- | -- | -- | Details |
| C00399 | BRD-A15501135 | BRD-A15501135 | -- | -- | -- | Details |
| C00400 | BRD-A15530910 | SDZ-21009 | HTR1A; HTR1B | Serotonin receptor antagonist; Adrenergic receptor antagonist | carpindolol | Details |
| C00401 | BRD-A15597386 | picrotoxin | GABRA1; GABRR1; GLRA2; GLRA3 | GABA receptor antagonist | -- | Details |
| C00402 | BRD-A15798299 | BRD-A15798299 | -- | -- | -- | Details |
| C00403 | BRD-A15909516 | rebamipide | -- | -- | -- | Details |